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| 1 | Regional assessment of cadmium pollution in agricultural lands and the potential health risk related to intensive mining activities: A case study in Chenzhou City, China显示文摘The purpose of this study was to assess the extent of cadmium (Cd) contamination in agricultural soil and its potential risk for people. Soils, rice, and vegetables from Chenzhou City, Southern China were sampled and analyzed. In the surface soils, the 95% confidence interval for the mean concentration of Cd varied between 2.72 and 4.83 mg/kg (P < 0.05) in the survey, with a geometric mean concentration of 1.45 mg/kg. Based on the GIS map, two hot spot areas of Cd in agricultural soils with high Cd concentrations were identified to be located around the Shizhuyuan, Jinshiling, and Yaogangxian mines, and the Baoshan and Huangshaping mines, in the center of the city. About 60% of the total investigated area, where the agricultural soil Cd concentration is above 1 mg/kg, is distributed in a central belt across the region. The critical distances, at which the soil Cd concentration were increased by the mining activities, from the mines of the soils were 23 km for the Baoshan mine, 46 km for the Huangshaping mine, and 63 km for the Shizhuyuan mine, respectively. These are distances calculated from models. The Cd concentrations in rice samples ranged from 0.01 to 4.43 mg/kg and the mean dietary Cd intake from rice for an adult was 191 μg/d. Results of risk indexes showed that soil Cd concentrations possessed risks to local residents whose intake of Cd from rice and vegetables grown in soils in the vicinity of the mine was 596 μg/d. | ZHAI Limei LIAO Xiaoyong CHEN Tongbin YAN Xiulan XIE Hua WU Bin WANG Lixia | 2008 | Journal of Environmental Sciences2008，20，6： | 35 |
| 2 | Identification and fine mapping of quantitative trait loci for seed vigor in germination and seedling establishment in rice显示文摘Seed vigor is an index of seed quality that is used to describe the rapid and uniform germination and the establishment of strong seedlings in any environmental conditions.Strong seed vigor in low-temperature germination conditions is particularly important in direct-sowing rice production systems. However, seed vigor has not been selected as an important breeding trait in traditional breeding programs due to its quantitative inherence. In this study, we identified and mapped eight quantitative trait loci(QTLs) for seed vigor by using a recombinant inbred population from a cross between rice(Oryza sativa L. ssp. indica) cultivars ZS97 and MH63.Conditional QTL analysis identified qSV-1, qSV-5b, qSV-6a, qSV-6b, and qSV-11 influenced seedling establishment and that qSV-5a, qSV-5c, and qSV-8 influenced only germination. Of these,qSV-1, qSV-5b, qSV-6a, qSV-6b, and qSV-8 were low-temperature-specific QTLs. Two major-effective QTLs, qSV-1, and qSV-5c were narrowed down to 1.13-Mbp and 400-kbp genomic regions, respectively. The results provide tightly linked DNA markers for the marker-assistant pyramiding of multiple positive alleles for increased seed vigor in both normal and low-temperature germination environments. | Lixia Xie Zhengwei Tan Yuan Zhou Rongbao Xu Laibao Feng Yongzhong Xing Xiaoquan Qi | 2014 | Journal of Integrative Plant Biology2014，56，8： | 17 |
| 3 | Chinese Stroke Association guidelines for clinical management of cerebrovascular disorders:executive summary and 2019 update of the management of high-risk population显示文摘Aim Cerebrovascular disease is the leading cause of death and disability in China,causing a huge burden among patients and their families.Hence,stroke prevention is critical,especially in the high-risk population.Here,we present the evidence-based guideline suitable for the Chinese population.Methods Literature search of PubMed and Cochrane library(from January 1964 to June 2019)was done.After thorough discussion among the writing group members,recommendations were listed and summarised.This guideline was reviewed and discussed by the fellow writing committees of the Chinese Stroke Association’s Stroke.Results This evidence-based guideline was written in three parts:controlling the risk factors of stroke,utilisation of antiplatelet agents and assessing the risks of first-ever stroke.All recommendations were listed along with the recommending classes and levels of evidence.Conclusions This guideline provides recommendations for primary prevention of cerebrovascular disease among high-risk population in China.Controlling related risk factors,appropriately using antiplatelet agents,assessing the risk of developing first-ever stroke should help reduce the rate of cerebrovascular disease in China. | Yilong Wang Shangrong Han Haiqiang Qin Huaguang Zheng Bin Jiang Yong Cao Yuan Gao Ling Guan Qian Jia Yong Jiang Yuming Jiao Shuya Li Yapeng Li Zixiao Li Wei Liu Xiaojuan Ru Dongling Sun Haixin Sun Penglian Wang Tingting Wang Lixia Zong Lei Guo Xuewei Xie Yuming Xu Yuyuan Xu Xiaomeng Yang Yingying Yang Mengyuan Zhou Wenzhi Wang Chinese Stroke Association Stroke Council Guideline Writing Committee | 2020 | Stroke & Vascular Neurology2020，5，3： | 11 |
| 4 | Synthesis, insecticidal activities and SAR studies of novel anthranilic diamides containing trifluoroethoxyl substituent and chiral amino acid moieties显示文摘Ryanodine receptors(RyRs) activator has become one class of popular insecticide because of its unique mode of action. In order to find more new RyRs activators as insecticidal agents, a series of 18 novel chiral anthranilic diamides were designed by introducing the D-alanine acid and D-serine acid esters as well as trifluoroethoxyl group into the anthranilic diamide skeleton and synthesized successfully based on anthranilic diamide and FKI-1033 structures. The structures of the title compounds Ia–i and IIa–i were confirmed by melting points,~1H NMR,^(13)C NMR, elemental analysis and specific optical rotation analysis.The preliminary bioassay results indicated that most of the title compounds exhibited considerable larvicidal activities against oriental armyworm at 10 mg/L, especially Ib, Ie and IIh showed remarkable insecticidal activities at 0.5 mg/L. The larvicidal activity against diamondback moth of Ia and IId were 80%and 90% respectively at 0.0001 mg/L, which was similar to that of chlorantraniliprole. The relationship between structure and insecticidal activity was analyzed to reveal a possible co-regulated effect of the chiral amino acid ester, halogen atom or cyano group, and trifluoroethyloxyl group of the skeleton structures of the title compounds, which will provide useful information for guiding the design and discovery of new RyRs activators and insecticidal agrochemicals. | Shaa Zhou Sha Zhou Yongtao Xie Xiangde Meng Baolei Wang Lixia Xiong Na Yang Zhengming Li | 2018 | Chinese Chemical Letters2018，29，8： | 3 |
| 5 | Anti-VEGF therapy prevents Müller intracellular edema by decreasing VEGF-A in diabetic retinopathy显示文摘Background:Although vascular endothelial growth factor A(VEGF-A)is known to play a key role in causing retinal edema,whether and how VEGF-A induces intracellular edema in the retina still remains unclear.Methods:Sprague-Dawley rats were rendered diabetic with intraperitoneal injection of streptozotocin.Intravitreal injection of ranibizumab was performed 8 weeks after diabetes onset.rMC-1 cells(rat Müller cell line)were treated with glyoxal for 24 h with or without ranibizumab.The expression levels of inwardly rectifying K^(+)channel 4.1(Kir4.1),aquaporin 4(AQP4),Dystrophin 71(Dp71),VEGF-A,glutamine synthetase(GS)and sodium-potassium-ATPase(Na^(+)-K^(+)-ATPase)were examined using Western blot.VEGF-A in the supernatant of the cell culture was detected with ELISA.The intracellular potassium and sodium levels were detected with specific indicators.Results:Compared with normal control,protein expressions of Kir4.1 and AQP4 were down-regulated significantly in diabetic rat retinas,which were prevented by ranibizumab.The above changes were recapitulated in vitro.Similarly,the intracellular potassium level in glyoxal-treated rMC-1 cells was increased,while the intracellular sodium level and Na^(+)-K^(+)-ATPase protein level remained unchanged,compared with control.However,ranibizumab treatment decreased intracellular sodium,but not potassium.Conclusion:Ranibizumab protected Müller cells from diabetic intracellular edema through the up-regulation of Kir4.1 and AQP4 by directly binding VEGF-A.It also caused a reduction in intracellular osmotic pressure. | Tianqin Wang Chaoyang Zhang Hai Xie Mengmeng Jiang Haibin Tian Lixia Lu Guo-Tong Xu Lin Liu Jingfa Zhang | 2021 | Eye and Vision2021，8，1： | 3 |
| 6 | Patch-Based Dark Channel Prior Dehazing for RS Multi-spectral Image显示文摘Remote sensing(RS) multi-spectral images are usually suffered from cloud and fog cover, which can lead to analysis troubles and application limitations. A novel patch-based dark channel prior dehaze method is proposed for solving this problem. An Atmospheric light(AL) curved surface hypothesis, instead of globally invariable plane, is applied to describe AL distribution, and a patch-based approach is given to estimate curved surface.By using AL curved surface estimation, a new recovering model for RS multi-spectral images is given to obtain dehaze-free images. Comparative experiments are conducted, those results illustrate that the proposed method can produces visually impressive restored images, and the proposed method is superior to other relative methods in terms of image quality evaluations. | WANG Lixia XIE Weixin PEI Jihong | 2015 | Chinese Journal of Electronics2015，24，3： | 2 |
| 7 | Design, Synthesis and Insecticidal Evaluation of Anthranilic Diamides Containing Optically Pure Amino Acid Moiety显示文摘N-pyridylpyrazolecarboxamide 衍生物的二个系列被介绍 D 丙氨酸酸酉旨和 D 丝氨酸酸酉旨进 chlorantraniliprole 的骨骼设计并且综合。获得的结构被 1 H NMR, 13 C NMR,元素的分析和特定的光旋转分析。初步的生物鉴定显示一些混合物与 chlorantraniliprole 比较对分开的 Mythimna 和 Plutella xylostella 显示了优秀杀虫的活动。特别地, IIq 在 0.01 mg·L −1 与 90% 的死亡率对 Plutella xylostella 显示出优秀杀虫的活动。A 3D-QSAR (CoMSIA ) 学习被执行以便揭示杀虫的结构活动关系并且显示未来工作。CoMSIA 学习证明在 pyrazole 的 3 位置的缺乏的组打电话找的大候补选手和电子是有利的,与氨基酸的酉旨组附近的一个小组一样。 | Shaa Zhou Sha Zhou Xuewen Hua Wei Wei Yongtao Xie Minggui Chen Xiangde Meng Ming Liu Lixia Xiong Na Yang Baolei Wang Zhengming Li | 2016 | Chinese Journal of Chemistry2016，34，12： | 2 |
| 8 | Large Room-Temperature Magnetoresistance in van der Waals Ferromagnet/Semiconductor Junctions显示文摘A magnetic tunnel junction(MTJ)is the core component in memory technologies,such as the magnetic random-access memory,magnetic sensors and programmable logic devices.In particular,MTJs based on twodimensional van der Waals(vd W)heterostructures offer unprecedented opportunities for low power consumption and miniaturization of spintronic devices.However,their operation at room temperature remains a challenge.Here,we report a large tunnel magnetoresistance(TMR)of up to 85%at room temperature(T=300 K)in vdW MTJs based on a thin(<10 nm)semiconductor spacer WSe_(2)layer embedded between two Fe_(3)GaTe_(2e)lectrodes with intrinsic above-room-temperature ferromagnetism.The TMR in the MTJ increases with decreasing temperature up to 164%at T=10 K.The demonstration of TMR in ultra-thin MTJs at room temperature opens a realistic and promising route for next-generation spintronic applications beyond the current state of the art. | Wenkai Zhu Shihong Xie Hailong Lin Gaojie Zhang Hao Wu Tiangui Hu Ziao Wang Xiaomin Zhang Jiahan Xu Yujing Wang Yuanhui Zheng Faguang Yan Jing Zhang Lixia Zhao Amalia Patanè Jia Zhang Haixin Chang Kaiyou Wang | 2022 | Chinese Physics Letters2022，39，12： | 2 |
| 9 | Design, Synthesis, Biological Evaluation and SARs of Novel Anthranilic Diamides Derivatives Containing Amide, Carbamate, Urea, and Thiourea Moieties显示文摘In order to discover potential ryanodine receptor insecticides, 21 novel anthranilic diamides analogues (C, D, E,and F) containing amide, carbamate, urea, and thiourea moieties were designed and synthesized based on bioiso-steric approach. The biological assays against oriental armyworm (Mythirnna separata) and diamondback moth(Plutella xylostella) indicated that these compounds displayed moderate to excellent activities. Especially, com-pound D1 showed 100% larvicidal activities against oriental armyworm at 1.0 mg.L^-1, equivalent to the standardchlorantraniliprole (100%, 1.0 mg·L^-1). Moreover, the larvicidal activity of D1 against diamondback moth was100% at 0.1 mg·L^-1, more effective than that of chlorantraniliprole (90%, 0.1 mg·L^-1). Therefore, D1 can be used asa new lead structure for the development of insecticidal agents. The preliminary structure-activity relationshipshowed that the introduction od carbamate groups into 4-position on the benzene ring of the N-phenylpyrazole moi-ety has a positive effect on the larvicidal activities. | Jingbo Liu Yuxin Li Xiulan Zhang Dandan Cheng Wei Wei Changchun Wu Yongtao Xie Lixia Xiong Zhengming Li | 2017 | Chinese Journal of Chemistry2017，35，3： | 2 |
| 10 | Design, Synthesis and Pharmacological Evaluation of Novel 4-Phenoxyquinoline Derivatives as Potential Antitumor Agents显示文摘 | HU Hao JIANG Mingyan XIE Lijun HU Gang ZHANG Cuirong ZHANG Lixia ZHOU Shunguang ZHANG Meihui GONG Ping | 2015 | Chemical Research in Chinese Universities2015，31，5： | 1 |
| 11 | Facile synthesis of Li2S@C composites as cathode for Li–S batteries显示文摘Lithium sulfide (Li2S) provides a promising route for lithium storage due to high theoretical specific capacity (1166 mAh g-1). The electrochemical performance of Li2S can be significantly enhanced by forming Li2S-carbon composites with the introduction of carbon. However, the complex synthesis method of Li2S-carbon composites restrains the large-scale productivity. Herein, we propose a facile route to prepare carbon coated Li2S-carbon nanotube composites (Li2S@C-CNT) via spray drying and heat treatment, which is a low-cost and large-scale method for facile synthesis of Li2S-carbon composites. For the Li2S@C-CNT composites, Li2S nanoparticles are contacted with surrounding particles due to the 3D CNTs framework. The novel construction not only suppresses the diffusion of polysulfides during cycling, but also remarkably accelerates the transport of electron and ion, resulting in a high specific capacity (1100 mAh g^-1) and good cycling performance. The rational designed architecture and good electrochemical performance of Li2S@C-CNT will pave the avenue for realizing high energy density of Li2S-based batteries. | Xin Chen Linfeng Peng Lixia Yuan Rui Zeng Jingwei Xiang Weilun Chen Kai Yuan Jie Chen Yunhui Huang Jia Xie | 2019 | Journal of Energy Chemistry2019，28，10： | 1 |
| 12 | Study of Bandgap Characteristics of 2D Magnetoplasma Photonic Crystal by Using M-FDTD Method显示文摘 | Yang Lixia Xie Yingtao Yu Pingping | 2011 | Microwave and Optical Technology Letters2011，53，8： | 1 |
| 13 | Rhizoma Paridis ethanol extract selectively inhibits the proliferation of HUVECs comparing to Lovo cells and shows anti-angiogenesis effects in a mouse model显示文摘 | Xiaoping Qian Lijing Zhu Jing Hu Min Li Li Xie Lifeng Wang Lixia Yu Baorui Liu | 2012 | Journal of Ethnopharmacology2012，，1： | 1 |
| 14 | Current status and future perspective of waste printed circuit boards recycling显示文摘 | ZENG Xianlai ZHENG Lixia XIE Henghua | 2012 | Proeedia Environmental Sciences2012，16，： | 1 |
| 15 | MicroRNA-146a is down-regulated in gastric cancer and regulates cell proliferation and apoptosis显示文摘 | Zhibo Hou Li Xie Lixia Yu Xiaoping Qian Baorui Liu | 2012 | Medical Oncology2012，，2： | 1 |
| 16 | Preparation of antimicrobial polyacrylonitrile fibers:Blending with polyacrylonitrile-co-3-allyl-5,5-dimethylhydantoin显示文摘 | Liuyang Wang Juan Xie Lixia Gu | 2006 | Polymer Bulletin2006，56，23： | 1 |
| 17 | Study ofbandgap characteristics of 2D magnetoplasma photon-ic crystal by using M-FDTD method 显示文摘 | YANG Lixia XIE Yingtao YU Pingping | 2011 | Microwaveand Optical Technology Letters2011，53，8： | 1 |
| 18 | Current status and future perspective of waste printed circuit boards recy- cling显示文摘 | Zeng Xianlai Zheng Lixia Xie Henghua | 2012 | Procedia Environmental Sci2012，16，596： | 1 |
| 19 | Salvianolic acid B inhibits Aβ fibril formation and disaggregates preformed fibrils and protects against Aβ-induced cytotoxicty显示文摘 | Siva Sundara Kumar Durairajan Qiuju Yuan Lixia Xie Wing-Sai Chan Wan-Fung Kum Irene Koo Chenli Liu Youqiang Song Jian-Dong Huang William L. Klein Min Li | 2007 | Neurochemistry International2007，，4： | 1 |
| 20 | Cell-free miR-24 and miR-30d, potential diagnostic biomarkers in malignant effusions显示文摘 | Li Xie Tingting Wang Shaorong Yu Xi Chen Lifeng Wang Xiaoping Qian Lixia Yu Yitao Ding Chenyu Zhang Baorui Liu | 2010 | Clinical Biochemistry2010，，2： | 1 |
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