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| 1 | Assessing the numbers of SNPs needed to establish molecular IDs and characterize the genetic diversityof soybean cultivars derived from Tokachi nagaha显示文摘The development of a core set of SNP molecular markers that could be widely used in soybean genetic research would greatly facilitate research into the genetic diversity of soybean.We conducted an analysis of Tokachi nagaha and 137 of its descendant soybean cultivars using 4044 SNP markers with the goal of determining the appropriate number of single-nucleotide polymorphisms(SNPs)needed to construct unambiguous molecular IDs and characterize genetic diversity based on a genetic distance matrix correlation method.When the number of SNPs was held constant,the number of accession pairs that could be distinguished increased as the polymorphism informative content(PIC)value of the SNPs increased.A core panel of 20 selected SNPs from 11 linkage groups with a mean PIC value of 0.3703 and a range of 0.3640–0.3749 was able to identify almost all of the accession pairs in our study[9445 pairs(99.92%)].The eight accession pairs that could not be identified with this core SNP set all originated from the same province and some of them had the same parental cultivars.The molecular IDs of the 138 accessions were constructed using the core 20 SNPs.It is known that both the number of SNPs and PIC values should be considered when SNPs are selected for use in the analysis of genetic diversity.In this study,when the PIC value was 0.3460,the correlation coefficient between the genetic distance matrices associated with a panel of 200 SNPs and the total population was>0.800,indicating satisfactory correlation.Our high-accuracy,high-resolution core SNP panel for germplasm fingerprinting and our findings about assessing genetic diversity will likely markedly improve the management and utilization efficiency of soybean germplasm resources. | Zhangxiong Liu Jun Li Xuhong Fan Nang Myint Phyu Sin Htwe Shuming Wang Wen Huang Jiyu Yang Lili Xing Lijun Chen Yinghui Li Rongxia Guan Ruzhen Chang Dechun Wang Lijuan Qiu | 2017 | The Crop Journal2017，5，4： | 10 |
| 2 | Self-Powered Implantable Skin-Like Glucometer for Real-Time Detection of Blood Glucose Level In Vivo显示文摘Implantable bioelectronics for analyzing physiological biomarkers has recently been recognized as a promising technique in medical treatment or diagnostics. In this study, we developed a self-powered implantable skinlike glucometer for real-time detection of blood glucose level in vivo. Based on the piezo-enzymatic-reaction coupling effect of GOx@ZnO nanowire, the device under an applied deformation can actively output piezoelectric signal containing the glucose-detecting information. No external electricity power source or battery is needed for this device, and the outputting piezoelectric voltage acts as both the biosensing signal and electricity power. A practical application of the skin-like glucometer implanted in mouse body for detecting blood glucose level has been simply demonstrated. These results provide a new technique path for diabetes prophylaxis and treatment. | Wanglinhan Zhang Linlin Zhang Huiling Gao Wenyan Yang Shuai Wang Lili Xing Xinyu Xue | 2018 | Nano-Micro Letters2018，10，2： | 9 |
| 3 | Relationship with spatial memory in diabetic rats and protein kinase Cγ,caveolin-1 in the hippocampus and neuroprotective effect of catalpol显示文摘 | Zhou Haicheng Liu Jing Ren Liyuan Liu Wei Xing Qian Men Lili Song Guirong Du Jianling | 2014 | Chinese Medical Journal2014，，5： | 7 |
| 4 | Efficacy and safety of Xinglouchengqi decoction for acute ischemic stroke with constipation:study protocol for a randomized con-trolled trial显示文摘OBJECTIVE: To investigate the efficacy and safety of Xinglouchengqi(XLCQ) decoction in treatment of acute ischemic stroke with constipation.METHODS: In this prospective, multicenter, assessor-blinded, randomized controlled trial, 360 eligible participants will be randomized to the XLCQ group or the control group. Participants in the XLCQ group will receive XLCQ decoction, while those in the control group will undergo clysis therapy using glycerin enemas or oral administration of lactulose solution. Both groups will undergo a treatment period of(5 ± 2) d and a 1-month follow-up.The primary outcome measure will be the Constipation Scale score. The secondary outcome measures will include scores on the National Institutes of Health Stroke Scale, the Traditional Chinese Medicine(TCM) Stroke Scale, the Diagnostic Scale for TCM Syndromes of Ischemic Stroke and TCM Scale for Syndrome of Phlegm-heat and Fu-organ Excess.Therapeutic mechanism outcomes and safety outcomes will also be assessed. Assessments will be conducted at baseline, at the end of the treatment period, and at the follow-up. Moreover, daily visits will be scheduled to grade the status of constipation during the treatment period.DISCUSSION: The results of this study will provide scientific and objective data with which to assess the efficacy and safety of XLCQ decoction for patients with acute ischemic stroke and constipation. | Chen Pei Zhang Yong Ling Lili Chen Xing Ren Yi Jiang Lan Wu Shuang Wang Wenting Wang Yuguang Zou Yihuai | 2017 | Journal of Traditional Chinese Medicine2017，37，6： | 7 |
| 5 | A water-evaporation-induced self-charging hybrid power unit for application in the Internet of Things显示文摘A self-charging hybrid power unit has been developed by integrating a water-evaporation-induced nano- generator with a flexible nano-patterned supercapacitor. The nanogenerator can harvest environmental thermal energy and mechanical energy through the water evaporation process, and the supercapacitor can be charged simultaneously. The former offers stable electrical power as output, whereas the Ppy- based supercapacitor shows a capacitance of 12.497 m F/cm^2 with 96.42% retention after 4,000 cycles. After filling the power unit with water as the fuel, it can be fully charged in about 20 min. The power unit can be flexibly integrated with electronic devices such as sensor nodes and wireless transmitters employ- ing the Internet of Things. This new approach can offer new possibilities in continuous future operation of randomly distributed electronic devices incorporated in the Internet of Things. | Haoxuan He Tianming Zhao Hongye Guan Tianyan Zhong Hui Zeng Lili Xing Yan Zhang Xinyu Xue | 2019 | Science Bulletin2019，64，19： | 5 |
| 6 | A Compound Algorithm of Denoising Using Second-Order and Fourth-Order Partial Differential Equations显示文摘In this paper,we propose a compound algorithm for the image restoration. The algorithm is a convex combination of the ROF model and the LET model with a parameter functionθ.The numerical experiments demonstrate that our compound algorithm is efficient and preserves the main advantages of the two models.In particular, the errors of the compound algorithm in L2 norm between the exact images and corresponding restored images are the smallest among the three models.For images with strong noises,the restored images of the compound algorithm are the best in the corresponding restored images.The proposed algorithm combines the fixed point method, an improved AMG method and the Krylov acceleration.It is found that the combination of these methods is efficient and robust in the image restoration. | Qianshun Chang Xuecheng Tai Lily Xing | 2009 | Numerical Mathematics(Theory,Methods and Applications)2009，2，4： | 5 |
| 7 | Wearable Battery-Free Perspiration Analyzing Sites Based on Sweat Flowing on ZnO Nanoarrays显示文摘We fabricated wearable perspiration analyzing sites for actively monitoring physiological status during exercises without any batteries or other power supply.The device mainly consists of ZnO nanowire(NW)arrays and flexible polydimethylsiloxane substrate.Sweat on the skin can flow into the flow channels of the device through capillary action and flow along the channels to ZnO NWs.The sweat flowing on the NWs(with lactate oxidase modification)can output a DC electrical signal,and the outputting voltage is dependent on the lactate concentration in the sweat as the biosensing signal.ZnO NWs generate electric double layer(EDL)in sweat,which causes a potential difference between the upper and lower ends(hydrovoltaic effect).The product of the enzymatic reaction can adjust the EDL and influence the output.This device can be integrated with wireless transmitter and may have potential application in constructing sports big data.This work promotes the development of next generation of biosensors and expands the scope of self-powered physiological monitoring system. | Wanglinhan Zhang Hongye Guan Tianyan Zhong Tianming Zhao Lili Xing Xinyu Xue | 2020 | Nano-Micro Letters2020，12，8： | 5 |
| 8 | SnO_2-CuO/graphene nanocomposites for high performance Li-ion battery anodes显示文摘The nanocomposites of SnO2-CuO/graphene are synthesized via a two-step method.CuO nanorods are firstly uniformly loaded on the graphene nanosheets,and then SnO2 nanoparticles are coated on CuO nanorods.SnO2-CuO/graphene nanocomposites exhibit high cyclability and capacity as anode of Li-ion battery.After 30 cycles,the capacity can maintain at 584 mAh g-1 at0.1C rate(10 h per half cycle).The high performance can be ascribed to the synergistic effect among SnO2 nanoparticles,CuO nanorods and graphene nanosheets.The results manifest that the nanocomposites of SnO2-CuO/graphene are very suitable for Li-ion battery anodes. | ZHAO Jun SHAN WanFei XIA XinBei WANG Qi XING LiLi | 2014 | Science China(Technological Sciences)2014，57，6： | 4 |
| 9 | A Self-Powered Breath Analyzer Based on PANI/PVDF Piezo-Gas-Sensing Arrays for Potential Diagnostics Application显示文摘The increasing morbidity of internal diseases poses serious threats to human health and quality of life.Exhaled breath analysis is a noninvasive and convenient diagnostic method to improve the cure rate of patients. In this study, a self-powered breath analyzer based on polyaniline/polyvinylidene fluoride(PANI/PVDF) piezogas-sensing arrays has been developed for potential detection of several internal diseases. The device works by converting exhaled breath energy into piezoelectric gassensing signals without any external power sources. The five sensing units in the device have different sensitivities to various gas markers with concentrations ranging from 0 to 600 ppm. The working principle can be attributed to the coupling of the in-pipe gas-flow-induced piezoelectric effect of PVDF and gas-sensing properties of PANI electrodes. In addition, the device demonstrates its use as an ethanol analyzer to roughly mimic fatty liver diagnosis.This new approach can be applied to fabricating new exhaled breath analyzers and promoting the development of self-powered systems. | Yongming Fu Haoxuan He Tianming Zhao Yitong Dai Wuxiao Han Jie Ma Lili Xing Yan Zhang Xinyu Xue | 2018 | Nano-Micro Letters2018，10，4： | 4 |
| 10 | Effects on Growth Performance and Feed Digestibility of Hainan Black Pigs by Adding Lysine in Low Protein Diet显示文摘[Objective] The paper was to study the effects on growth performance and feed digestibility of Hainan black pigs by adding lysine in low protein diet.[Method] A total of 36 Hainan black pigs with the body weight of(46.34 ±3.06) kg were randomly divided into three groups:control group(protein level 15%,lysine level 0.83%),experimental group I(protein level 13%,0.83%),and experimental group II(protein level 13%,lysine level 1.03),each group had three replicates of four pigs.The trial lasted 35 d.[Result] The growth performance of Hainan black pig in group II had no significant difference with that in control group(P>0.05).The apparent digestibility of crude protein and phosphorus of Hainan black pigs in Group II increased significantly(P<0.05),which were increased by 10.08% and 11.85% respectively compared to the control group;the apparent digestibility of calcium was increased,but the difference was not significant(P>0.05).[Conclusion] It will not reduce the growth performance of Hainan black pig when the protein level of diet is reduced by 2% and the lysine level is increased to 1.03%.It is recommended that the diet can be used in the production of Hainan black pig. | Wei Limin Liu Quanwei Sun Ruiping Zheng Xinli Wang Feng Tan Shuyi Huang Lili Xing Manping | 2018 | Animal Husbandry and Feed Science2018，10，2： | 4 |
| 11 | Effect of Pelleted Total Mixed Ration on Production Performance and Serum Biochemical Index of Growing Hainan Black Goats显示文摘[Objective] The paper was to investigate effects of pelleted total mixed ration on production performance and serum biochemical index of growing Hainan black goats.[Method] Twenty-four growing Hainan black goats with the same genetic backgrounds and similar initial weight of(10.05±0.049) kg were randomly assigned into two treatments, and supplied with Juncao + concentrate(control group), pelleted total mixed ration(experimental group), respectively. The trial lasted 50 d.[Result] The final weight, daily gain and feed intake of experimental group were significantly higher than those of control group(P<0.05), but the feed/gain ratio of experimental group was markedly lower than that of control group(P<0.05). Compared with the control group, the gross profit of experimental group significantly increased( P <0.05).[Conclusion] Pelleted total mixed ration led to better production performance of growing Hainan black goat. | Liu Quanwei Wang Feng Wei Limin Huang Lili Sun Ruiping Xing Manping Zheng Xinli | 2019 | Animal Husbandry and Feed Science2019，11，1： | 4 |
| 12 | Comparison of pigment composition and melanin content among white,light-green,dark-green,and purple morphs of sea cucumber,Apostichopus japonicus显示文摘Sea cucumber, Apostichopus japonicus(Selenka), is a commercially important marine species in China. Among the differently colored varieties sold in China, white and purple sea cucumbers have the greatest appeal to consumers. Identification of the pigments that may contribute to the formation of different color morphs of sea cucumbers will provide a scientific basis for improving the cultivability of desirable color morphs. In this study,sea cucumbers were divided into four categories according to their body color: white, light green, dark green, and purple. The pigment composition and contents in the four groups were analyzed by high performance liquid chromatography(HPLC). The results show that the pigment contents differed significantly among the white, lightgreen, dark-green, and purple sea cucumbers, and there were fewer types of pigments in white sea cucumber than in the other color morphs. The only pigments detected in white sea cucumbers were guanine and pteroic acid.Guanine and pteroic acid are structural colors, and they were also detected in light-green, dark-green, and purple sea cucumbers. Every pigment detected, except for pteroic acid, was present at a higher concentration in purple morphs than in the other color morphs. The biological color pigments melanin, astaxanthin, β-carotene, and lutein were detected in light-green, dark-green, and purple sea cucumbers. While progesterone and lycopene,which are also biological color pigments, were not detected in any of the color morphs. Melanin was the major pigment contributing to body color, and its concentration increased with deepening color of the sea cucumber body. Transmission electron microscopy analyses revealed that white sea cucumbers had the fewest epidermal melanocytes in the body wall, and their melanocytes contained fewer melanosomes as well as non-pigmented pre-melanosomes. Sea cucumbers with deeper body colors contained more melanin granules. In the body wall of dark-green and purple sea cucumbers, melanin granules were secreted out of the cell. The results of this study provide evidence for the main factors responsible for differences in coloration among white, light-green, darkgreen, and purple sea cucumbers, and also provide the foundation for further research on the formation of body color in sea cucumber, A. japonicus. | XING Lili SUN Lina LIU Shilin LI Xiaoni MIAO Ting ZHANG Libin YANG Hongsheng | 2017 | Acta Oceanologica Sinica2017，36，12： | 3 |
| 13 | Analysis of characteristics of time-frequency correlations between runoff,tidal range and salinity in the Changjiang Estuary显示文摘Power spectrum and cross-wavelet transform analysis was adopted to study the time-frequency characteristics and multiscale correlations between runoff,tidal range and salinity in the Changjiang Estuary based on the runoff data collected at the Datong Station,the tidal range measured at the Baozhen Station,and the salinity at the Baogang Station from 2008 to 2009.The variations of the salinity showed significant periodicity at scales of 2-3,7-8,14-15 and 26-30 d.The correlation between the salinity and the runoff and the tidal range were found to be significantly related to shock at scales of 5-7,14-15,26-30 d and 0.5 a.The correlation between the runoff and the salinity was mainly in the same phase,while the correlation between the tidal range and the salinity was in the antiphase.Different frequency bands were related to different degrees,and their relevance increased as the resonance frequency decreased.In addition,changes of the seasonal runoff were obvious.Specifically,a point of discontinuity was reached in early June with a cycle of 7-8 d,which coincided with the periodicity of plum rains in the Changjiang-Huaihe region.High-frequency changes (8-16 d period) of the salinity corresponded to the time domain in January-April 2008,February-April 2009 and October-December 2009 and exhibited an approximately 0.5 a (184 d) long frequency oscillation.Short-period changes were found to be stronger than long-period changes.Cross-wavelet transforms for the salinity,the runoff and the tidal range revealed local features in the time domain,while the significant levels of different periodic oscillations were observed in the frequency domain.The correlation characteristics of the salinity and the runoff were significant in the 80-90 d frequency domain,indicating that the major impact of the runoff on the salinity was reflected in seasonal changes.The tidal range on the small scale of 14-15 and 30-32 d was more obvious than the runoff. | FEI Yuejun XU Lili DU Panjun GUAN Qinle KANG Xing XIAO Wenjun | 2011 | Acta Oceanologica Sinica2011，30，5： | 3 |
| 14 | Comparison of lateral episiotomy,traditional midwifery without episiotomy,and hands-off techniques delivery on pelvic floor function显示文摘Background Prolonged vaginal delivery times and episiotomy are associated with damage to the muscles of the pelvic floor,and with complications that include postpartum sexual dysfunction and urinary stress incontinence.This study was to compare the pelvic floor function among postpartum women who underwent three midwifery practices during labor:lateral episiotomy,traditional midwifery without episiotomy,and hands-off techniques delivery.Methods We included 320 primipara who were full-term pregnancy and underwent vaginal delivery in Department of Obstetrics,Peking University People’s Hospital,China.117 women had episiotomy during labor and were classified into the lateral episiotomy group;103 had traditional midwifery without episiotomy and were classified into the traditional midwifery practice group;and 100 experienced hands-off techniques during labor and were classified into the hands-off techniques delivery group.The duration of the second stage of labor,and postpartum pelvic floor muscle strength were compared between the three study groups.Results There were no significant differences between the three groups for the duration of the second stage of labor and postpartum pelvic floor muscle strength(P>0.05).However,the incidence of postpartum urinary stress incontinence and sexual dysfunction in the hands-off techniques delivery group was significantly lower than in the lateral episiotomy groups and the traditional midwifery practice group(P<0.01).Conclusions Hands-off techniques delivery could reduce damage to the pelvic floor and improve the quality of life for women after delivery. | Jingjing Gong Lili Xing Xiaodan Li Xiaona Wang Huijuan Chen | 2021 | Gynecology and Obstetrics Clinical Medicine2021，1，1： | 2 |
| 15 | Slaughtering Performance and Meat Quality of Hainan Black Goat and Its Hybrid Offsprings with Nubian Black Goat显示文摘In order to compare the slaughter performance and meat quality of Hainan black goats and hybrid offsprings of Nubian Black Goat and Hainan Black Goat, six 7-month-old Hainan black goats and six hybrid offsprings were selected to determine slaughter performance and muscle quality. The results showed that hybridization of Nubian black goat and Hainan black goat significantly improved the production performance and slaughter performance of hybrid offsprings (P>0.05). The meat quality of F1 hybrid black goat had no significant difference with that of Hainan black goat except for the hardness and elasticity (P<0.05). Therefore, the crossbred progenies of Nubian black goat and Hainan black goat have advantages in meat yield and meat performance, and the main meat quality indexes are not significantly different, which meets the market requirements for high-yield and high-quality hybrid combinations, and can be used for cross promotion. | Wei Limin Sun Ruiping Liu Yan Liu Ruina Liu Quanwei Zheng Xinli Wang Feng Huang Lili Xing Manping | 2019 | Animal Husbandry and Feed Science2019，11，2： | 2 |
| 16 | Chemotherapy initiation with single-course methotrexate alone or combined with dactinomycin versus multi-course methotrexate for low-risk gestational trophoblastic neoplasia: a multi-centric randomized clinical trial显示文摘We aimed to evaluate the effectiveness and safety of single-course initial regimens in patients with low-risk gestational trophoblastic neoplasia(GTN).In this trial (NCT01823315),276 patients were analyzed.Patients were allocated to three initiated regimens:single-course methotrexate(MTX),single-course MTX+dactinomycin(ACTD),and multi-course MTX(control arm).The primary endpoint was the complete remission(CR)rate by initial drug(s).The primary CR rate was 64.4%with multi-course MTX in the control arm.For the single-course MTX arm,the CR rate was 35.8%by one course;it increased to 59.3%after subsequent multi-course MTX,with non-inferiority to the control(difference-5.1%,95%confidence interval(CI)-19.4%to 9.2%,P=0.014).After further treatment with multi-course ACTD,the CR rate(93.3%)was similar to that of the control(95.2%,P=0.577).For the single-course MTX+ACTD arm,the CR rate was 46.7%by one course,which increased to 89.1%after subsequent multi-course,with non-inferiority(difference 24.7%,95%CI 12.8%-36.6%,P<0.001)to the control.It was similar to the CR rate by MTX and further ACTD in the control arm(89.1%vs.95.2%,P=0.135).Four patients experienced recurrence,with no death,during the 2-year follow-up.We demonstrated that chemotherapy initiation with single-course MTX may be an alternative regimen for patients with low-risk GTN. | Lili Chen Ling Xi Jie Jiang Rutie Yin Pengpeng Qu Xiuqin Li Xiaoyun Wan Yaxia Chen Dongxiao Hu Yuyan Mao Zimin Pan Xiaodong Cheng Xinyu Wang Qingli Li Danhui Weng Xi Zhang Hong Zhang Quanhong Ping Xiaomei Liu Xing Xie Beihua Kong Ding Ma Weiguo Lu | 2022 | Frontiers of Medicine2022，16，2： | 2 |
| 17 | Energy Management Strategy Considering Multi-time-scale Operational Modes of Batteries for the Grid-connected Microgrids Community显示文摘The advantages and promoting applications of the microgrids community(MGC)allows for a critical step being taken toward a smart grid.An energy management strategy(EMS)is essential to intelligently coordinate the operations of the MGC.This paper presents a multi-time-scale EMS consid-ering battery operational modes for grid-connected MGCs.The proposed strategy consists of two modules:day-ahead integrated optimization and realtime distributed compensation.The first module aims to minimize the operational cost of the MGC considering battery free-overcharging protecting.This problem is solved by the mixed integer linear programming(MILP)sim-ulating two charging/discharging modes:limited-current mode and constant-voltage mode.The second module is installed in local MGs to correct the optimizing deviations of the day-ahead static scheduling,which are caused by predicting errors of renewable energy and loads.The main contribution of this work is integrating the advantages of global optimization of the centralized method and the fast computing speed of the distributed method.Experimental results prove the proposed EMS is feasible and effective.The computing time at each updating step is reduced by 75%on average,which has the potential to be adopted in engineering. | Xiaowen Xing Lili Xie Hongmin Meng Xin Guo Lei Yue Josep M.Guerrero | 2020 | CSEE Journal of Power and Energy Systems2020，6，1： | 1 |
| 18 | Interferon-Induced Guanylate Binding Protein-1 (GBP-1) Mediates an Antiviral Effect against Vesicular Stomatitis Virus and Encephalomyocarditis Virus显示文摘 | Sylvia L. Anderson Jill M. Carton Jing Lou Lily Xing Berish Y. Rubin | 1999 | Virology1999，，1： | 1 |
| 19 | Predictably synthesizing a library of white-light-emitting perovskites显示文摘The low-dimensional organic-inorganic halide perovskites with self-trapped exciton emission have promising prospects for single-phase white-light emitters. However, so far, these broadband white-light-emitting(BWLE) perovskites were synthesized by trial-and-error testing spacing molecules. Here, we developed a steric hindrance regulation strategy to predictably synthesize BWLE perovskites. The molecules containing C–C(–NH_(2))–C groups were introduced into low-dimensional perovskites, which brings a large steric hindrance in-plane orientation. The bigger C–C(–NH_(2))–C bond angle would induce larger structural distortion in perovskites, which leads to the higher rate of self-trapping of excitons and the deeper self-trapping depth. The photoluminescence spectra of the synthesized perovskites can cover the cool-to-warm white light region. Overall, we fabricated a material library consisting of 40 kinds of BWLE compounds according to this strategy. Our findings develop a general strategy to synthesize BWLE perovskites and offer a material platform for optoelectronic applications. | Ludan Niu Lili Zhao Deyu Li Qian Chen Mingming Zhang Jing Luan Lei Wang Weigao Xu Jun Xing | 2023 | Science China Chemistry2023，66，3： | 1 |
| 20 | Experimental and kinetic modeling study of the low- and intermediate-temperature oxidation of dimethyl ether显示文摘 | Zhandong Wang Xiaoyuan Zhang Lili Xing Lidong Zhang Friederike Herrmann Kai Moshammer Fei Qi Katharina Kohse-H?inghaus | 2014 | Combustion and Flame2014，，： | 1 |
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