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| 1 | Quantifying the characteristics of particulate matters captured by urban plants using an automatic approach显示文摘It is widely accepted that urban plant leaves can capture airborne particles. Previous studies on the particle capture capacity of plant leaves have mostly focused on particle mass and/or size distribution. Fewer studies, however, have examined the particle density, and the size and shape characteristics of particles, which may have important implications for evaluating the particle capture efficiency of plants, and identifying the particle sources. In addition, the role of different vegetation types is as yet unclear. Here, we chose three species of different vegetation types, and firstly applied an object-based classification approach to automatically identify the particles from scanning electron microscope(SEM)micrographs. We then quantified the particle capture efficiency, and the major sources of particles were identified. We found(1) Rosa xanthina Lindl(shrub species) had greater retention efficiency than Broussonetia papyrifera(broadleaf species) and Pinus bungeana Zucc.(coniferous species), in terms of particle number and particle area cover.(2) 97.9% of the identified particles had diameter ≤10 μm, and 67.1% of them had diameter ≤2.5 μm. 89.8% of the particles had smooth boundaries, with 23.4% of them being nearly spherical.(3) 32.4%–74.1% of the particles were generated from bare soil and construction activities, and 15.5%–23.0% were mainly from vehicle exhaust and cooking fumes. | Jingli Yan Lin Lin Weiqi Zhou Lijian Han Keming Ma | 2016 | Journal of Environmental Sciences2016，28，1： | 3 |
| 2 | Facile synthesis of hierarchical Na2Fe(SO4)2@rGO/C as high-voltage cathode for energy density-enhanced sodium-ion batteries显示文摘Fe-based sulfates are ideal cathode candidates for sodium-ion batteries(SIBs) owing to their high operating voltage and low cost but suffer from the nature of poor power performance. Herein, a hierarchical porous Na2Fe(SO4)2@reduced graphene oxide/carbon dot(Na2Fe(SO4)2@rGO/C) with low carbon content(4.12 wt%) was synthesized via a facile homogeneous strategy benefiting for engineering application,which delivers excellent sodium storage performance(high voltage plateau of 3.75 V, 85 m Ah g-1 and330 Wh kg-1 at 0.05 C;5805 W kg-1 at 10 C) and high Na+diffusion coefficient(1.19 × 10-12 cm2 s-1).Moreover, the midpoint voltage of assembled full cell could reach 3.0 V. The electron transfer and reaction kinetics are effectively boosted since the nanoscale Na2Fe(SO4)2 is supported by a robust crosslinked carbon matrix with rGO sheets and carbon dots. The slight rGO sheets sufficiently enhance the electron transfer like a current collecter and restrain the aggregation, as well as ensure smooth ion channels. Meanwhile, the carbon dots in the whole space connect with Na2Fe(SO4)2 and help rGO to promote the conductivity of the electrode. Ex-situ X-ray powder diffraction and X-ray photoelectron spectrometry analysis confirm the high reversibility of this sodiation/desodiation process. | Ge Yao Xixue Zhang Yongliang Yan Jiyu Zhang Keming Song Juan Shi Liwei Mi Jinyun Zheng Xiangming Feng Weihua Chen | 2020 | Journal of Energy Chemistry2020，29，11： | 3 |
| 3 | Hydrocarbon Generation and Expulsion of the Upper Triassic T3x5Source Rocks in the Western Sichuan Depression: Assessment for Unconventional Natural Gas显示文摘Tight-sand gas in the Jurassic and shale gas within the fifth member of Xujiahe Formation(T3x5) in the Western Sichuan Basin(WSD) are currently regarded as the most prolific emerging unconventional gas plays in China. This study conducted a conventional evaluation of T3x5 source rocks in the WSD, and investigated their hydrocarbon generation and expulsion characteristics, including intensity, efficiency and amount. The results show that, the T3x5 source rocks are thick(generally >200 m), and have a high total organic content(TOC), ranging from 2.5 to 4.5 wt%. It is thus indivative of a great hydrocarbon generation potential when they underwent high thermal evolution(Ro>1.2%) in the area. In addition, an improved method of hydrocarbon generation potential is applied, indicating that the source rocks reached a hydrocarbon expulsion threshold with vitrinite reflectance(Ro) reaching 1.06%, and that the comprehensive hydrocarbon expulsion efficiency is about 60%. The amount of hydrocarbon generation and expulsion from T3x5 source rocks is 3.14×1010 t and 1.86×1010 t, respectively, with a residual amount of 1.28×1010 t within them. Continuous-type tight-sand gas is predicted to have developed in the Jurassic in the Chengdu Sag of the WSD because of the good source-reservoir configuration; the Jurassic sandstone reservoirs are tight, and the gas expelled from the T3x5 source rocks migrates for very short distances vertically and horizontally. The amount of gas accumulation in the Jurassic reservoirs derived from T3x5 source rocks is up to 9.3×108 t. Geological resources of shale gas are up to 1.05×1010 t. Small differences between the amounts calculated by the volumetric method and those obtained by hydrocarbon generation potential method may be due to other gas accumulations present within interbedded sands associated with gas shales. | GUO Yingchun SONG Yan PANG Xiongqi WANG Youwei YANG Keming LI Boyuan | 2015 | Acta Geologica Sinica(English Edition)2015，89，1： | 2 |
| 4 | An improved procedure for Agrobacterium-mediated transformation of trifoliate orange (Poncirus trifoliata L. Raf.) via indirect organogenesis显示文摘 | Xiuping Zou Demou Li Xiaoying Luo Keming Luo Yan Pei | 2008 | In Vitro Cellular & Developmental Biology - Plant2008，，3： | 1 |
| 5 | Application of BP Network-Based Multi-sensor Fusion Techniques in measurement of the Unburned Carbon in Fly Ash显示文摘 | Gaowei Yan Gang Xie Keming Xie | 2005 | ISNN LNCS2005，34，： | 1 |
| 6 | Existence and global exponential stability of periodic solution for delayed high- order Hopfield-type neural network显示文摘 | XIONG Hong YAN Keming WANG Baiyan | 2006 | Physics Letters A2006，52，： | 1 |
| 7 | Application of BP Network-Based Multi-sensor Fusion Techniques in measurement of the Unburned Carbon in Fly Ash显示文摘 | Gaowei Yan Gang Xie Keming Xie | 2005 | ISNN2005，3498，： | 1 |
| 8 | ERECT PANICLE2 Encodes a Novel Protein That Regulates Panicle Erectness in Indica Rice显示文摘 | Zhu Keming Tang Ding Yan Changjie Chi Zhengchang Yu Hengxiu Chen Jianmin Liang Jiansheng Gu Minghong Cheng Zhukuan | 2010 | Genetics2010，，2： | 1 |
| 9 | Enhancement of CAR-T cell activity against cholangiocarcinoma by simultaneous knockdown of six inhibitory membrane proteins显示文摘Background:Existing treatments for cholangiocarcinoma have poor efficacy.However,chimeric antigen receptor-T(CAR-T)cells are emerging as a potential therapeutic strategy.Solid tumors possess multiple adverse factors in an immunosuppressive microenvironment that impair CAR-T cell infiltration and function.This study aimed to improve the function of CAR-T cells through knock down immune checkpoints and immunosuppressive molecular receptors.Methods:We evaluated the expression of epidermal growth factor receptor(EGFR)and B7 homolog 3 protein(B7H3)antigens in cholangiocarcinoma tissues using immunohistochemistry and screened specific immune checkpoints in the cholangiocarcinoma microenvironment via flow cytometry.Subsequently,we engineered CAR-T cells targeting EGFR and B7H3 antigens.We simultaneously knocked down immune checkpoints and immunosuppressive molecular receptors in CAR-T cells by constructing two clusters of small hairpin RNAs and evaluated the engineered CAR-T cells for antitumor activity both in vitro,using tumor cell lines and cholangiocarcinoma organoid models,and in vivo,using humanized mouse models.Results:We observed high expression of EGFR and B7H3 antigens in cholangiocarcinoma tissues.EGFR-CAR-T and B7H3-CAR-T cells demonstrated specific anti-tumor activity.We found an abundance of programmed cell death protein 1(PD-1),T cell immunoglobulin and mucin domain-containing protein 3(Tim-3),and T cell immunoglobulin and ITIM domain(Tigit)on infiltrated CD8^(+)T cells in the cholangiocarcinoma microenvironment.We then decreased the expression of these 3 proteins on the surface of CAR-T cells,named PTG-scFV-CAR-T cells.Furthermore,we knocked-down the expression of transforming growth factor beta receptor(TGFβR),interleukin-10 receptor(IL-10R),and interleukin-6 receptor(IL-6R)of PTG-scFV-CAR-T cells.Those cells,named PTG-T16R-scFVCAR-T cells,potently killed tumor cells in vitro and promoted apoptosis of tumor cells in a cholangiocarcinoma organoidmodel.Finally,the PTG-T16R-scFv-CART cells showed greater inhibitory effect on tumor growth in vivo,and were superior in prolonging the survival of mice.Conclusions:Our results revealed that PTG-T16R-scFV-CAR-T cells with knockdown of sextuplet inhibitory molecules exhibited strong immunity against cholangiocarcinoma and long-term efficacy both in vitro and in vivo.This strategy provides an effective and personalized immune cell therapy against cholangiocarcinoma. | Yidan Qiao Jie Chen Xuemei Wang Shumei Yan Jizhou Tan Baijin Xia Yongjian Chen Keming Lin Fan Zou Bingfeng Liu Xin He Yiwen Zhang Xu Zhang Hui Zhang Xiangyuan Wu Lijuan Lu | 2023 | Cancer Communications2023，43，7： | 0 |
| 10 | Intermediary roles of prospective memory and retrospective memory in the comorbidity of depression and pain显示文摘Background Patients who suffer comorbidity of major depressive disorder(MDD)and chronic pain(CP)maintain a complex interplay between maladaptive prospective memory(PM)and retrospective memory(RM)with physical pain,and their complications are still unknown.Aims We aimed to focus on the full cognitive performance and memory complaints in patients with MDD and CP,patients with depression without CP,and control subjects,considering the possible influence of depressed affect and chronic pain severity.Methods According to the fifth edition of the Diagnostic and Statistical Manual of Mental Disorders and the criteria given by the International Association of Pain,a total of 124 participants were included in this cross-sectional cohort study.Among them,82 depressed inpatients and outpatients from Anhui Mental Health centre were divided into two groups:a comorbidity group(patients with MDD and CP)(n=40)and a depression group(patients with depression without CP)(n=42).Meanwhile,42 healthy controls were screened from the hospital’s physical examination centre from January 2019 to January 2022.The Hamilton Depression Rating Scale-24(HAMD-24)and Beck Depression Inventory-II(BDI-II)were used to evaluate the severity of depression.The Pain Intensity Numerical Rating Scale(PI-NRS),Short-Form McGill Pain Questionnaire-2 Chinese version(SF-MPQ-2-CN),Montreal Cognitive Assessment-Basic Section(MoCA-BC),and Prospective and Retrospective Memory Questionnaire(PRMQ)were used to assess pain-related features and the global cognitive functioning of study participants.Results The impairments in PM and RM differed remarkably among the three groups(F=7.221,p<0.001;F=7.408,p<0.001)and were severe in the comorbidity group.Spearman correlation analysis revealed the PM and RM were positively correlated with continuous pain and neuropathic pain(r=0.431,p<0.001;r=0.253,p=0.022 and r=0.415,p<0.001;r=0.247,p=0.025),respectively.Regression analysis indicated a significant positive relationship between affective descriptors and total BDI-II score(β=0.594,t=6.600,p<0.001).Examining the mediator pathways revealed the indirect role of PM and RM in patients with comorbid MDD and CP.Conclusions Patients with comorbid MDD and CP presented more PM and RM impairments than patients with MDD without CP.PM and RM are possibly mediating factors that affect the aetiology of comorbid MDD and CP. | Hua Gao Qingrong Xia Xulai Zhang Yuanyuan Chen Junwei Yan Jianliang Gao Loufeng Zhang Jie Zhang Keming Wang Chao Li Peijun Ju Cuizhen Zhu | 2023 | General Psychiatry2023，36，1： | 0 |
| 11 | A Pyrazine-Based 2D Conductive Metal-Organic Framework for Efficient Lithium Storage显示文摘The merits of intrinsic electrical conductivity, high specific surface area, tunable chemical composition and tailor-made properties enable two-dimensional conductive metal-organic frameworks (2D c-MOFs) as promising next-generation electrode materials in the field of energy storage and conversion. Herein, we have designed and synthesized a novel pyrazine-based 2D c-MOF (TPQG-Cu-MOF) bearing extended π-conjugated structure and abundant redox active sites. Thanks to the excellent redox reversibility of pyrazine units and CuO2 units, as well as the insolubility of the rigid framework skeleton, TPQG-Cu-MOF as the cathode material of lithium-ion battery exhibits a reversible specific capacity (150.2 mAh·g–1 at 20 mAh·g–1), good cycling stability (capacity retention of 82.6% after 500 cycles at 1 A·g–1) and excellent rate performance. Comprehensive ex-situ spectroscopic studies revealed the reversible redox activity of pyrazine units and CuO2 units of TPQG-Cu-MOF during the Li+ insertion/extraction process. The deepening fundamental understanding of the structure-property relationship was proposed, which might pave the way for further development of efficient MOF-based energy storage devices. | Xiaoxiao Sun Xiaoli Yan Keming Song Ting Zhang Zongfan Yang Xi Su Weihua Chen Long Chen | 2023 | Chinese Journal of Chemistry2023，41，14： | 0 |
| 12 | Expert Consensus on Nutritional Support for Children with Congenital Heart Disease(2023 Edition)显示文摘The second edition of the expert consensus on pediatric nutrition was formed based on a global update of pedia-tric nutrition guidelines or consensus worldwide,the management of congenital heart disease,and the results of multi-center clinical nutrition research for congenital heart disease following thefirst Chinese consensus edition of 2016.The consensus was also shaped by the results of three discussion sessions and two questionnaires con-ducted by the 13-member collaboration group.This process was informed by both clinical guidelines and expert consensus.The quality of literature,both in English and Chinese,and the level of recommendations were evaluated using the Grading of Recommendations Assessment,Development,and Evaluations(GRADE)system. | Xuming Mo Wei Cai Jirong Qi Zhuoming Xu Ying Wang Weihui Yan Shoujun Li Nianguo Dong Xinxin Chen Jinfen Liu Qiang Shu Jimei Chen Haibo Zhang Hao Zhang Quansheng Xing Qi An Xiaofeng Li Xu Wang Yan He Junwu Su Taibing Fan Teng Ming Weibing Tang Li Hong Jinghao Zheng Ming Ye Guocheng Sun Yiqun Ding Liang Tao Yifeng Yang Zhongshi Wu Hua Cao Qiang Wang Keming Yang Libing Zhang Ping Wen Yanqin Cui Bo Zhai Yong Zou Qingya Tang Rui Chen Chun Wu Zhiyu Feng Caixia Liu Yaping Mi Rufang Zhang Ke Lin Xin Li Mingan Pi Xiangming Fan Shanshan Shi Peng Huang Zhengxia Pan Jiafeng Qi Renwei Chen Shuguang Tao Yaqin Shu Huifeng Zhang Lan Jiang Min Da Nishant Patel Liang Hu Cardiac Surgery Group of Pediatric Surgery Society of Chinese Medical Association and Parenteral Enteral Nutrition Society of Chinese Medical Association | 2023 | Congenital Heart Disease2023，18，6： | 0 |
| 13 | Environmental factors affecting regional differences and decadal variations in the buried flux of marine organic carbon in eastern shelf sea areas of China显示文摘To characterize environmental factors controlling decadal-scale variations in the buried flux of marine organic carbon(BFC_(m))in the eastern shelf sea areas of China(ECSS),four well preserved sediment cores collected from the central Yellow Sea mud(CYSM)area,the Yellow Sea Coastal Current(YSCC)area and the Changjiang River Estuary(CRE)were investigated in this study.In the CYSM,variations in BFC_(m) were found to be dependent on variations in primary productivity and to exhibit a cyclical trend possibly related to fluctuations in the Pacific Decadal Oscillation(PDO)and the East Asian winter monsoon index(EAWM).In the YSCC,BFC_(m) likewise depends on primary productivity.Prior to the 1950s,variations in BFC_(m) were similar to that of the EAWM.After the 1950s,BFC_(m) increased rapidly and exhibited maximum values in the surface layer,consistent with an increase in primary productivity caused by the input of terrestrial nutrients associated with China’s economic development.In the CRE,variations in BFC_(m) were affected by several competing factors making it difficult to identify clear relationships between variations in BFC_(m) and primary productivity.In contrast,long-term variability in BFC_(m) is more similar to changes in the Changjiang River sediment load.Thus,it is speculated that the construction of dams along the Changjiang River may be the main cause of variations in BFC_(m) in this area.Given the disproportionate effects of human activities on marine environments and decadal variations in BFC_(m) in the ECSS,careful attention should be paid to regional differences in organic carbon preservation and environmental changes lest estimates of these values be made imprecise or inaccurate. | Qian Yang Keming Qu Shu Yang Yao Sun Yan Zhang Mingying Zhou | 2021 | Acta Oceanologica Sinica2021，40，6： | 0 |
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