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| 1 | Preoperative diagnosis of malignant pulmonary nodules in lung cancer screening with a radiomics nomogram显示文摘Background:Lung cancer is the most commonly diagnosed cancer worldwide.Its survival rate can be significantly improved by early screening.Biomarkers based on radiomics features have been found to provide important physiological information on tumors and considered as having the potential to be used in the early screening of lung cancer.In this study,we aim to establish a radiomics model and develop a tool to improve the discrimination between benign and malignant pulmonary nodules.Methods:A retrospective study was conducted on 875 patients with benign or malignant pulmonary nodules who underwent computed tomography(CT)examinations between June 2013 and June 2018.We assigned 612 patients to a training cohort and 263 patients to a validation cohort.Radiomics features were extracted from the CT images of each patient.Least absolute shrinkage and selection operator(LASSO)was used for radiomics feature selection and radiomics score calculation.Multivariate logistic regression analysis was used to develop a classification model and radiomics nomogram.Radiomics score and clinical variables were used to distinguish benign and malignant pulmonary nodules in logistic model.The performance of the radiomics nomogram was evaluated by the area under the curve(AUC),calibration curve and Hosmer-Lemeshow test in both the training and validation cohorts.Results:A radiomics score was built and consisted of 20 features selected by LASSO from 1288 radiomics features in the training cohort.The multivariate logistic model and radiomics nomogram were constructed using the radiomics score and patients’age.Good discrimination of benign and malignant pulmonary nodules was obtained from the training cohort(AUC,0.836;95%confidence interval[CI]:0.793-0.879)and validation cohort(AUC,0.809;95%CI:0.745-0.872).The Hosmer-Lemeshow test also showed good performance for the logistic regression model in the training cohort(P=0.765)and validation cohort(P=0.064).Good alignment with the calibration curve indicated the good performance of the nomogram.Conclusions:The established radiomics nomogram is a noninvasive preoperative prediction tool for malignant pulmonary nodule diagnosis.Validation revealed that this nomogram exhibited excellent discrimination and calibration capacities,suggesting its clinical utility in the early screening of lung cancer. | Ailing Liu Zhiheng Wang Yachao Yang Jingtao Wang Xiaoyu Dai Lijie Wang Yuan Lu Fuzhong Xue | 2020 | Cancer Communications2020，40，1： | 22 |
| 2 | Generation of arbitrary vector vortex beams on hybrid-order Poincaré sphere显示文摘We propose theoretically and verify experimentally a method of combining a q-plate and a spiral phase plate to generate arbitrary vector vortex beams on a hybrid-order Poincaré sphere. We demonstrate that a vector vortex beam can be decomposed into a vector beam and a vortex, whereby the generation can be realized by sequentially using a q-plate and a spiral phase plate. The generated vector beam, vortex, and vector vortex beam are verified and show good agreement with the prediction. Another advantage that should be pointed out is that the spiral phase plate and q-plate are both fabricated on silica substrates, suggesting the potential possibility to integrate the two structures on a single plate. Based on a compact method of transmissive-type transformation, our scheme may have potential applications in future integrated optical devices. | Zhenxing Liu Yuanyuan Liu Yougang Ke Yachao Liu Weixing Shu Hailu Luo Shuangchun Wen | 2017 | Photonics Research2017，5，1： | 18 |
| 3 | Giant photonic spin Hall effect in momentum space in a structured metamaterial with spatially varying birefringence显示文摘The photonic spin Hall effect(SHE)in the reflection and refraction at an interface is very weak because of the weak spin-orbit interaction.Here,we report the observation of a giant photonic SHE in a dielectric-based metamaterial.The metamaterial is structured to create a coordinate-dependent,geometric Pancharatnam–Berry phase that results in an SHE with a spin-dependent splitting in momentum space.It is unlike the SHE that occurs in real space in the reflection and refraction at an interface,which results from the momentum-dependent gradient of the geometric Rytov–Vladimirskii–Berry phase.We theorize a unified description of the photonic SHE based on the two types of geometric phase gradient,and we experimentally measure the giant spin-dependent shift of the beam centroid produced by the metamaterial at a visible wavelength.Our results suggest that the structured metamaterial offers a potential method of manipulating spin-polarized photons and the orbital angular momentum of light and thus enables applications in spin-controlled nanophotonics. | Xiaohui Ling Xinxing Zhou Xunong Yi Weixing Shu Yachao Liu Shizhen Chen Hailu Luo Shuangchun Wen Dianyuan Fan | 2015 | Light(Science & Applications)2015，4，1： | 15 |
| 4 | Time-frequency characteristics based motion estimation and imaging for high speed spinning targets via narrowband waveforms显示文摘This paper focuses on the motion parameters estimation and inversed synthetic aperture radar (ISAR) imaging for the high-speed spinning targets via the time-frequency characteristics. Assuming that the translational motion is compensated with the available motion compensation techniques, then the residual part of translational motion and the spinning motion are estimated with high precision based on the timefrequency characteristics. Combining with the procedure of the motion estimation, a novel coherent timefrequency spectrum intensity redistribution method, coherent single range Doppler interferometry (CSRDI), is proposed, which provides higher resolution and sustain lower signal to noise rate (SNR) than the current approach. Numerical simulation confirms the validity and high precision of the proposed approaches. | ZHANG Lei , LI YaChao, LIU Yan, XING MengDao & BAO Zheng National Lab for Radar Signal Processing, Xidian University, Xi’an 710071, China | 2010 | Science China(Information Sciences)2010，53，8： | 9 |
| 5 | Five-wavelength optical-resolution photoacoustic microscopy of blood and lymphatic vessels显示文摘Optical-resolution photoacoustic microscopy(OR-PAM)has been developed for anatomical,functional,and molecular imaging but usually requires multiple scanning for different contrasts.We present five-wavelength OR-PAM for simultaneous imaging of hemoglobin concentration,oxygen saturation,blood flow speed,and lymphatic vessels in single raster scanning.We develop a five-wavelength pulsed laser via stimulated Raman scattering.The five pulsed wavelengths,i.e.,532,545,558,570,and 620∕640 nm,are temporally separated by several hundreds of nanoseconds via different optical delays in fiber.Five photoacoustic images at these wavelengths are simultaneously acquired in a single scanning.The 532-and 620∕640-nm wavelengths are used to image the blood vessels and dye-labeled lymphatic vessels.The blood flow speed is measured by a dual-pulse method.The oxygen saturation is calculated and compensated for by the Grüneisen-relaxation effect.In vivo imaging of hemoglobin concentration,oxygen saturation,blood flow speed,and lymphatic vessels is demonstrated in preclinical applications of cancer detection,lymphatic clearance monitoring,and functional brain imaging. | Chao Liu Jiangbo Chen Yachao Zhang Jingyi Zhu Lidai Wang | 2021 | Advanced Photonics2021，3，1： | 7 |
| 6 | Polarization evolution of vector beams generated by q-plates显示文摘The polarization evolution of vector beams(VBs) generated by q-plates is investigated theoretically and experimentally.An analytical model is developed for the VB created by a general quarter-wave q-plate based on vector diffraction theory.It is found that the polarization distribution of VBs varies with position and the value q.In particular,for the incidence of circular polarization,the exit vector vortex beam has polarization states that cover the whole surface of the Poincarésphere,thereby constituting a full Poincarébeam.For the incidence of linear polarization,the VB is not cylindrical but specularly symmetric,and exhibits an azimuthal spin splitting.These results are in sharp contrast with those derived by the commonly used model,i.e.,regarding the incident light as a plane wave.By implementing q-plates with dielectric metasurfaces,further experiments validate the theoretical results. | WEIXING SHU XIAOHUI LING XIQUAN FU YACHAO LIU YOUGANG KE HAILU LUO | 2017 | Photonics Research2017，5，2： | 7 |
| 7 | Investigation of β-Ga2O3 films and β-Ga2O3/GaN heterostructures grown by metal organic chemical vapor deposition显示文摘In this work,(-201)β-Ga2O3 films are grown on GaN substrate by metal organic chemical vapor deposition(MOCVD).It is revealed that theβ-Ga2O3 film grown on GaN possesses superior crystal quality,material homogeneity and surface morphology than the results of common heteroepitaxialβ-Ga2O3 film based on sapphire substrate.Further,the relevance between the crystal quality of epitaxialβ-Ga2O3 film and theβ-Ga2O3/GaN interface behavior is investigated.Transmission electron microscopy result indicates that the interface atom refactoring phenomenon is beneficial to relieve the mismatch strain and improve the crystal quality of subsequentβ-Ga2O3 film.Moreover,the energy band structure ofβ-Ga2O3/GaN heterostructure grown by MOCVD is investigated by X-ray photoelectron spectroscopy and a large conduction band offset of 0.89 eV is obtained.The results in this work not only convincingly demonstrate the advantages ofβ-Ga2O3 films grown on GaN substrate,but also show the great application potential of MOCVDβ-Ga2O3/GaN heterostructures in microelectronic applications. | YaChao Zhang YiFan Li ZhiZhe Wang Rui Guo ShengRui Xu ChuanYang Liu ShengLei Zhao JinCheng Zhang Yue Hao | 2020 | Science China(Physics,Mechanics & Astronomy)2020，63，11： | 2 |
| 8 | Devel- opment of a new skeletal mechanism for n-decane oxida- tion under engine-relevant conditions based on a decoup- ling methodology显示文摘 | Chang Yachao Jia Ming Liu Yaodong | 2013 | Combustion and Flame2013，160，8： | 1 |
| 9 | A clinical assessment of the Glidescope videolaryngoscope in nasotracheal intubation with general anesthesia显示文摘 | Fushan Xue Guohua Zhang Jin Liu Xuanying Li Haitao Sun Xiao Wang Chengwen Li Kunpeng Liu Yachao Xu Yi Liu | 2006 | Journal of Clinical Anesthesia2006，，8： | 1 |
| 10 | Photonic Hall effect and helical Zitterbewegung in a synthetic Weyl system显示文摘Systems supporting Weyl points have gained increasing attention in condensed physics,photonics and acoustics due to their rich physics,such as Fermi arcs and chiral anomalies.Acting as sources or drains of Berry curvature,Weyl points exhibit a singularity of the Berry curvature at their core.It is,therefore,expected that the induced effect of the Berry curvature can be dramatically enhanced in systems supporting Weyl points.In this work,we construct synthetic Weyl points in a photonic crystal that consists of a honeycomb array of coupled rods with slowly varying radii along the direction of propagation.The system possesses photonic Weyl points in the synthetic space of two momenta plus an additional physical parameter with an enhanced Hall effect resulting from the large Berry curvature in the vicinity of the Weyl point.Interestingly,a helical Zitterbewegung(ZB)is observed when the wave packet traverses very close to a Weyl point,which is attributed to the contribution of the non-Abelian Berry connection arising from the near degenerate eigenstates. | Weimin Ye Yachao Liu Jianlong Liu Simon A.R.Horsley Shuangchun Wen Shuang Zhang | 2019 | Light(Science & Applications)2019，8，1： | 1 |
| 11 | Regulating electronic structure of porous nickel nitride nanosheet arrays by cerium doping for energy-saving hydrogen production显示文摘Water electrolysis for energy-efficient H_(2)production coupled with hydrazine oxidation reaction(HzOR)is prevailing,while the sluggish electrocatalysts are strongly hindering its scalable application.Herein,we schemed a novel porous Ce-doped Ni3N nanosheet arrays grown on nickel foam(Ce-Ni3N/NF)as a remarkable bifunctional catalyst for both hydrogen evolution reaction and HzOR.Significantly,the overall hydrazine splitting system can achieve low cell voltages of 0.156 and 0.671 V at 10 and 400 mA·cm^(−2),and the system is remarkably stable to operate over 100 h continuous test at the high-current-density of 400 mA·cm^(−2).Various characterizations prove that the porous nanosheet arrays expose more active sites,and more excellent diffusion kinetics and lower charge-transfer resistance,therefore boosting catalytic performance.Furthermore,density functional theory calculation reveals that the incorporation of Ce can effectively optimize the free energy of hydrogen adsorption and promote intrinsic catalytic activity of Ni_(3)N. | Rui-Qing Li Suyuan Zeng Bin Sang Chaozhuang Xue Konggang Qu Yu Zhang Wei Zhang Guangyu Zhang Xinghui Liu Jie Deng Olivier Fontaine Yachao Zhu | 2023 | Nano Research2023，16，2： | 1 |
| 12 | A neural network-based production process modeling and variable importance analysis approach in corn to sugar factory显示文摘Corn to sugar process has long faced the risks of high energy consumption and thin profits.However,it’s hard to upgrade or optimize the process based on mechanism unit operation models due to the high complexity of the related processes.Big data technology provides a promising solution as its ability to turn huge amounts of data into insights for operational decisions.In this paper,a neural network-based production process modeling and variable importance analysis approach is proposed for corn to sugar processes,which contains data preprocessing,dimensionality reduction,multilayer perceptron/convolutional neural network/recurrent neural network based modeling and extended weights connection method.In the established model,dextrose equivalent value is selected as the output,and 654 sites from the DCS system are selected as the inputs.LASSO analysis is first applied to reduce the data dimension to 155,then the inputs are dimensionalized to 50 by means of genetic algorithm optimization.Ultimately,variable importance analysis is carried out by the extended weight connection method,and 20 of the most important sites are selected for each neural network.The results indicate that the multilayer perceptron and recurrent neural network models have a relative error of less than 0.1%,which have a better prediction result than other models,and the 20 most important sites selected have better explicable performance.The major contributions derived from this work are of significant aid in process simulation model with high accuracy and process optimization based on the selected most important sites to maintain high quality and stable production for corn to sugar processes. | Yi Tong Mou Shu Mingxin Li Yingwei Liu Ran Tao Congcong Zhou You Zhao Guoxing Zhao Yi Li Yachao Dong Lei Zhang Linlin Liu Jian Du | 2023 | Frontiers of Chemical Science and Engineering2023，17，3： | 1 |
| 13 | 1.7 kV normally-off p-GaN gate high-electron-mobility transistors on a semi-insulating SiC substrate显示文摘A study of 1.7 kV normally-off p-GaN gate high-electron-mobility transistors(HEMTs)on SiC substrates is presented.The fabricated p-GaN HEMT with a gate-drain spacing LGD=5μm exhibited a threshold voltage of 1.10 V,a maximum drain current of 235 mA/mm,an ON/OFF ratio of 10^(8),and a breakdown voltage of 440 V.Benefiting from the semi-insulating and high-critical-electric-field substrate,the p-GaN HEMT with LGD=23μm achieved the remarkably high breakdown voltage of 1740 V with substrate grounded.This breakdown voltage is very high compared with the reported values for p-GaN HEMTs on silicon substrates with substrate grounded.The vertical breakdown voltage for the p-GaN-on-SiC material exceeded 3 kV with substrate grounded.In addition,the maximum drain current at 500 K was 48%of that at 300 K with a negligible threshold voltage shift.These results indicate the substantial potential of p-GaN gate HEMTs on SiC substrates for high-voltage power applications. | Shenglei ZHAO Jincheng ZHANG Yachao ZHANG Lansheng FENG Shuang LIU Xiufeng SONG Yixin YAO Jun LUO Zhihong LIU Shengrui XU Yue HAO | 2023 | Science China(Information Sciences)2023，66，2： | 1 |
| 14 | Asterosaponin 1 induces endoplasmic reticulum stress-associated apoptosisin A549 human lung cancer cells显示文摘 | Yachao Zhao Changliang Zhu Xiaofei Li Zhipei Zhang Yuan Yuan Yunfeng Ni Tonggang Liu Sanming Deng Jinbo Zhao Yunjie Wang | 2011 | Oncology Reports2011，，4： | 1 |
| 15 | Effect of magnetic layer thickness on magnetic properties of Ce-Fe-B thin films显示文摘The Ce_2 Fe_(14)B thin films with a notable out-of-plane c-axis texture were prepared by DC magnetron sputtering on a Ta buffer layer. The morphological and magnetic properties were investigated. The thickness of the magnetic layer had a dramatic effect on the formation of Ce_2 Fe_(14)B phase,and excellent magnetic properties(H_(ci)≈4.25 kOe, M_r/M_s≈0.81) were observed for the Ce-Fe-B film with the thickness d_m = 200 nm. The results of the hysteresis loops for Ce-Fe-B film(d_m = 200 nm) at various measured temperatures show that a decoupling between the hard and the soft phases is observed at low temperatures, which is due to the regions with quite low anisotropy provided by the a-Fe. Moreover. it is clear that significantly various magnetization behaviors between the films with d_m = 200 and 300 nm were observed with a similar trend due to the existence of the a-Fe soft phase. | Yachao Sun Minggang Zhu Wei Liu Rui Han Wei Li | 2018 | Journal of Rare Earths2018，36，6： | 1 |
| 16 | All-angle reflectionless negative refraction with ideal photonic Weyl metamaterials显示文摘Negative refraction,an unnatural optical phenomenon in which the incident and the refracted waves reside on the same side of the surface normal,has been demonstrated with the invention of negative index media based on artificially engineered photonic structures called metamaterials.It has received wide attention due to its potential applications in imaging,nonlinear optics,and electromagnetic cloaking.However,it is highly challenging to realize negative refraction operating at all angles and with the perfect transmission.In this work,leveraging the recent development in topological photonics,we propose to realize reflection less negative refraction for all incident angles with a topological metamaterial.The proposed metamaterial possesses two Weyl points of opposite topological charges.By interfacing the metamaterial with a perfect electric conductor(PEC)or a perfect magnetic conductor(PMC),the Fermi arc connecting the two Weyl points can take the form of a half-circle possessing a positive or a negative refractive index.Importantly,due to the topological protection,there is no reflection at the interface between the PEC and PMC covered areas,leading to the observation of all-angle negative refraction without reflection at the boundary.Our work provides a new platform for manipulating the propagation of surface waves,which may find applications in the construction of integrated photonic devices. | Yachao Liu Guo Ping Wang John B.Pendry Shuang Zhang | 2022 | Light(Science & Applications)2022，11，10： | 0 |
| 17 | Synthesis, properties, and applications of large-scale two-dimensional materials by polymer-assisted deposition显示文摘Two-dimensional(2D) materials have attracted considerable attention because of their novel and tunable electronic,optical, ferromagnetic, and chemical properties. Compared to mechanical exfoliation and chemical vapor deposition, polymer-assisted deposition(PAD) is more suitable for mass production of 2D materials owing to its good reproducibility and reliability. In this review, we summarize the recent development of PAD on syntheses of 2D materials. First, we introduce principles and processing steps of PAD. Second, 2D materials, including graphene, MoS2, and MoS2/glassy-graphene heterostructures, are presented to illustrate the power of PAD and provide readers with the opportunity to assess the method. Last, we discuss the future prospects and challenges in this research field. This review provides a novel technique for preparing 2D layered materials and may inspire new applications of 2D layered materials. | Hongtao Ren Yachao Liu Lei Zhang Kai Liu | 2019 | Journal of Semiconductors2019，40，6： | 0 |
| 18 | Alkaline hydrogen production promoted by small-molecule modification on flowerlike Co_(2)(OH)_(2)CO_(3)显示文摘Developing a low-cost and high-efficiency nonprecious metal-based catalyst for hydrogen evolution reaction(HER) is of great significance for the utilization of hydrogen energy.In this work,we report a molecular-modification strategy to fabricate a self-supported hydrogen evolution electrode,specially by grafting the macrocyclic molecules(HHTP=2,3,6,7,10,11-hexahydroxytriphenylene) on the surface of a cobaltous dihydroxy carbonate(COC) seed layer.The HHTP-COC electrode is endowed with a rodlike structure,which provides favorable access for charge transportation and mass exchange.The macrocyclic molecule structure in HHTP can be grafted on COC and improve the electrical conductivity,while the interaction between HHTP and COC induces the rearrangement of charge configuration on the surface.Due to the combination effects of several aspects,the HHTP-COC electrode achieves astonishing HER activity,with a low overpotential of 61.0 mV(η_(10),at the current density of 10 mA cm^(-2)) and excellent stability in alkaline condition.This kind of interface engineering based on the organic molecules can be applied to the design and manufacture of electrocatalysts in the field of energy conversion and storage. | Yue Liu Huan Zhang Chen Yang Ziyang Xu Yiyang Shi Xukun Zhu Xinde Duan Ling Qin Yachao Jin Li Song Mingdao Zhang Hegen Zheng | 2023 | Journal of Energy Chemistry2023，，9： | 0 |
| 19 | Current collapse suppressed GaN diodes with 38 Watts high RF power rectifier capability显示文摘Microwave power transmission(MPT)could realize the point-to-point long-distance transfer of energy without any wires,which makes it attractive for solar-powered satellites,drones,and implantable medical devices,and has aroused enormous attention[1].Microwave rectifiers could convert RF(radio frequency)energy into DC(direct current)power,which is the essential element of the receiving end of the MPT system[2,3]. | Kui DANG Zhilin QIU Shudong HUO Peng ZHAN Huining LIU Yachao ZHANG Jing NING Hong ZHOU Jincheng ZHANG | 2024 | Science China(Information Sciences)2024，67，2： | 0 |
| 20 | Thermodynamic Evaluation of Transcritical CO_(2) Heat Pump Considering Temperature Matching under the Constraint of Heat Transfer Pinch Point显示文摘The non-linear temperature glide in the supercritical CO_(2) cooling process makes the heat transfer pinch point of heat exchanger show multiplicity,like size,location distribution and quantity,which makes the thermodynamic performance of the CO_(2) transcritical cycle more complex and eventually affects the evaluation of the optimal operating state of the system.Based on the second law of thermodynamics and the constraints of heat transfer pinch,a thermodynamic evaluation method of CO_(2) transcritical heat pump system was proposed according to the degree of temperature matching.The influence mechanism of multi-characteristic change of heat transfer pinch point on temperature matching degree and the effect of temperature matching degree on thermodynamic performance of CO_(2) transcritical heat pump system were discussed.The relationship between temperature matching degree,COP and exergy efficiency of the system was analyzed.It is considered that the change of temperature matching index value can clearly characterize the change trends of COP and exergy efficiency.That is,the smaller the temperature matching degree is,the closer the temperature distribution of heat transfer fluids on both sides of the heat exchanger is to Lorenz cycle,and the greater the COP and exergy efficiency are.Furthermore,by monitoring the outlet temperature of the CO_(2) cooler,which has an essential relationship with the temperature matching degree during the heat exchange process,the deviation between actual and optimal working condition can be judged online,which is beneficial to real-time evaluation of the working state of the system. | LIU Ruijian GAO Fengling LIANG Kunfeng WANG Lin WANG Moran MI Guoqiang LI Yachao | 2021 | Journal of Thermal Science2021，30，3： | 0 |
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