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| 1 | Fra-1 protooncogene regulates IL-6 expression in macrophages and promotes the generation of M2d macrophages显示文摘肿瘤微型环境(TME ) 在肿瘤房间的生长起一个突出的作用。作为 TME 的主要煽动性的部件, M2d 巨噬细胞被 TME 教育以便他们采用支持肿瘤转移和前进的一个抑制免疫力的角色。有 6 月的 Fra-1 形式使活跃之物 protein-1 heterodimers 合伙并且驾驶基因抄写。Fra-1 被认为急速地导致 tumorigenesis 和前进。然而,在 M2d 巨噬细胞的产生的 Fra-1 的功能的角色糟糕迄今为止被理解。这里,我们表明那 4T1 乳房的癌房间与 RAW264.7 巨噬细胞房间 co 有教养,扭曲 RAW264.7 巨噬细胞房间区别进 M2d 巨噬细胞。4T1 房间在 RAW264.7 房间,然后 Fra-1 刺激 Fra-1 的 de novo overexpression 绑在 interleukin 6 (IL-6 ) 在 RAW264.7 房间增加 cytokine IL-6 的生产的倡导者。在 autocrine 的 IL-6 幕塑造扭曲 RAW264.7 巨噬细胞房间区别进 M2d 巨噬细胞。这些调查结果开的新卓见进怎么颠倒 M2d 导致巨噬细胞的有免疫力的忍耐改进 immunotherapeutic 途径的功效。 | Qingshan Wang Hong Ni Lan Lan Xiaoli Wei Rong Xiang Yue Wang | 2010 | Cell Research2010，20，6： | 12 |
| 2 | Three Cases of COVID-19 Variant Delta With and Without Vaccination——Chengdu City,Sichuan Province,April-May,2021显示文摘On April 26,2021,a 33-year-old male Chinese sailor returning from India via Kathmandu,Nepal,tested positive for the coronavirus disease 2019(COVID-19)by Chengdu Customs and was confirmed positive by Chengdu CDC(Case A).On May 2,2021,a housewife in the same flight tested positive for COVID-19 by Pengzhou CDC in Sichuan Province during her quarantine period and was confirmed positive by Chengdu CDC the next day(Case B). | Heng Chen Yi Mao Zhenhua Duan Liang Wang Yue Cheng Yingxue Dai Haixia Luo Wenjun Xie Shuangfeng Fan Yuzhen Zhou Jingpei Xu Lan Feng Liwen Hu Zhu Liu Xian Liang Liangshuang Jiang Xiaoli Tuo | 2021 | China CDC weekly2021，3，25： | 5 |
| 3 | Research on Testing Technology of Relay Protection for Intelligent Substations显示文摘Intelligent substations adopt various kinds of new technologies, including information sharing technology based on IEC61850, digital sampling technology, synchronization technology, and network transmission technology. Relay protection equipment faces all the challenges brought by the application of these new technologies. After analyzing the demand for test, the authors propose testing methods and technical requirements targeting the test items in great need, including ICD model file test, digital interface performance test, coordination performance test with merging unit and smart terminal, network pressure test. And the problems occurring during the tests are summarized. | Zhan Rongrong Li Yanjun Zhang Xiaoli Zhan Zhihua Yu Yue Chen Zhengguang | 2014 | Electricity2014，25，5： | 5 |
| 4 | Impact of STAT4 gene silencing on the expression profile of proteins in EL-4 cells显示文摘The signal transducers and activators of transcription (STATs) have diverse biological functions and are involved in cell differentiation, proliferation, development, apoptosis and inflammation. Several constitutively activated STATs have been observed in a wide variety of human cancer cell lines and primary tumor cells, including blood malignancies and solid neoplasias. Although regulatory T (Treg) cells induce immune tolerance by suppressing host immune responses against selfor nonself-antigens, thus playing critical roles in preventing autoimmune diseases, they might inhibit antitumor im-munity and promote tumor growth. Our previous findings suggest that the supernatant from STAT4silenced tumor cell culture can significantly increase the ratio of CD4+ CD25+ Foxp3+ regulatory T cells among splenic cells in vitro, when compared to that from normal tumor cell culture. In the present study, we identified that the mouse lymphoma cell line EL-4 expressed a high level of STAT4, and silencing of STAT4 by siRNA did not change the expression levels of TGF-β and IL-10 in EL-4 cells. Two-dimensional electrophoresis was conducted to examine the difference of expression profiles of proteins between normal and STAT4-silenced EL4 cells. Some of the protein which has been changed may induce CD4+ CD25+ Foxp3+ regulatory T cells in vitro. | WEI XiaoLi NI Hong WANG QingShan XIANG Rong WANG Yue | 2009 | Chinese Science Bulletin2009，54，18： | 4 |
| 5 | Effects of different aperture-sized type I collagen/silk fibroin scaffolds on the proliferation and differentiation of human dental pulp cells显示文摘This study aimed at evaluate the effects of different aperture-sized type I collagen/silk fibroin(CSF)scaffolds on the proliferation and differentiation of human dental pulp cells(HDPCs).The CSF scaffolds were designed with 3D mapping software Solidworks.Three different aperture-sized scaffolds(CSF1-CSF3)were prepared by low-temperature deposition 3D printing technology.The morphology was observed by scanning electron microscope(SEM)and optical coherence tomography.The porosity,hydrophilicity and mechanical capacity of the scaffold were detected,respectively.HDPCs(third passage,1105 cells)were seeded into each scaffold and investigated by SEM,CCK-8,alkaline phosphatase(ALP)activity and HE staining.The CSF scaffolds had porous structures with macropores and micropores.The macropore size of CSF1 to CSF3 was 421627 lm,579636 lm and 707643 lm,respectively.The porosity was 69.862.2%,80.162.8%and 86.563.3%,respectively.All these scaffolds enhanced the adhesion and proliferation of HDPCs.The ALP activity in the CSF1 group was higher than that in the CSF3 groups(P<0.01).HE staining showed HDPCs grew in multilayer within the scaffolds.CSF scaffolds significantly improved the adhesion and ALP activity of HDPCs.CSF scaffolds were promising candidates in dentine-pulp complex regeneration. | Shihui Jiang Zhaoxia Yu Lanrui Zhang Guanhua Wang Xiaohua Dai Xiaoli Lian Yan Yan Linpu Zhang Yue Wang Ruixin Li Huiru Zou | 2021 | Regenerative Biomaterials2021，8，4： | 2 |
| 6 | Engineering and modification of microbial chassis for systems and synthetic biology显示文摘Engineering and modifying synthetic microbial chassis is one of the best ways not only to unravel the fundamental principles of life but also to enhance applications in the health,medicine,agricultural,veterinary,and food industries.The two primary strategies for constructing a microbial chassis are the top-down approach(genome reduction)and the bottom-up approach(genome synthesis).Research programs on this topic have been funded in several countries.The‘Minimum genome factory’(MGF)project was launched in 2001 in Japan with the goal of constructing microorganisms with smaller genomes for industrial use.One of the best examples of the results of this project is E.coli MGF-01,which has a reduced-genome size and exhibits better growth and higher threonine production characteristics than the parental strain[1].The‘cell factory’project was carried out from 1998 to 2002 in the Fifth Framework Program of the EU(European Union),which tried to comprehensively understand microorganisms used in the application field.One of the outstanding results of this project was the elucidation of proteins secreted by Bacillus subtilis,which was summarized as the‘secretome’[2].The GTL(Genomes to Life)program began in 2002 in the United States.In this program,researchers aimed to create artificial cells both in silico and in vitro,such as the successful design and synthesis of a minimal bacterial genome by John Craig Venter's group[3].This review provides an update on recent advances in engineering,modification and application of synthetic microbial chassis,with particular emphasis on the value of learning about chassis as a way to better understand life and improve applications. | Haotian Chi Xiaoli Wang Yue Shao Ying Qin Zixin Deng Lianrong Wang Shi Chen | 2019 | Synthetic and Systems Biotechnology2019，4，1： | 2 |
| 7 | Gold nanoparticles based digital color analysis for quinidine detection显示文摘In this contribution,we developed a novel digital color analysis of gold nanoparticles(AuNPs) for pharmaceutical detection by choosing quinidine as an example.It was found that the color of AuNPs colloid solution changed from red to blue in the presence of different concentrations of quinidine,and the color information of each solution could be digitalized with tricolor(RGB) system.Under the optimum conditions,the R value of the solution was found to be linear with the natural logarithm of concentration of quinidine in the range of 112 384 nmol/L.This method has the advantages of rapid,economical and simple,and can serve as a potential alternative to traditional spectrophotometry for practical use. | ZOU BoZhou LIU Yue YAN XiaoLi HUANG ChengZhi | 2013 | Chinese Science Bulletin2013，58，18： | 2 |
| 8 | Amperometric biosensor for NADH and ethanol based on electroreduced graphene oxide–polythionine nanocomposite film显示文摘 | Zou Li Yi Huang Li Chen Xiaoli Qin Zhao Huang Yaping Zhou Yue Meng Jing Li Siyu Huang Yan Liu Wen Wang Qingji Xie Shouzhuo Yao | 2013 | Sensors & Actuators: B Chemical2013，，： | 1 |
| 9 | 4SCAR-GD2-modified T-cell therapy in neuroblastoma withamplification: A case report with over 4-year follow-up data显示文摘Introduction: Neuroblastoma (NB) is the most common extracranial solid tumor among children. The 5-year event-free survival rate for high-risk (HR) NB is still poor, especially for patients with advanced NB withMYCN gene amplification. Chimeric antigen receptor T (CAR-T) cell therapy is a new treatment for HR-NB.Case presentation: A 55-month-old boy with stage IV HR-NB received 4th-generation CAR-T cells that target disialoganglioside GD2, as consolidation maintenance treatment after intensive chemotherapy, surgery, and autologous stem-cell transplantation. As of February 2019, his CAR-T follow-up time was 37.5 months, indicating prolonged survival. Cranial MRI and ultrasound showed no mass;123I-metaiodobenzylguanidine (123I-MIBG) scan was negative.Conclusion: GD2-CAR-T cells may be an effective treatment option for NB patients withMYCN amplification. | Xiao Xu Wen Zhao Zhixia Yue Maoquan Qin Mei Jin Lung-Ji Chang Xiaoli Ma | 2020 | Pediatric Investigation2020，4，1： | 1 |
| 10 | Pressure-induced changes in the magnetic properties of the single crystal of Mn_3 single-molecule magnet显示文摘The magnetic measurements of the single crystal of Mn3 single-molecule magnet under high pressure at T=2 K have been performed.We find both the antiferromagnetic intermolecular coupling parameter J and the effective energy barrier to vary compared with the measurements at low pressure.The increase of|J|is estimated to be 12%at 0.7 GPa when compared with that of0 GPa,whereas the effective energy barrier becomes smaller with increasing pressure.Our results demonstrate that the intermolecular interaction of single-molecule magnet can be changed by pressure.Compared with the normal magnetic alloy,the effect of pressure on the magnetic properties of Mn3 is much more prominent,which implies that Mn3 may have great potential in magnetic multifunctional material. | CUI Yan WU Yue LI YanRong LIU RuiYuan DONG XiaoLi WANG YunPing | 2014 | Science China(Physics,Mechanics & Astronomy)2014，57，7： | 1 |
| 11 | Dynamic Changes of Sediment Load in the Middle Reaches of the Yellow River Basin,China and Implications for Eco-Restoration显示文摘 | Yue Xiaoli Mu Xingmin Zhao Guangju | 2014 | Ecological Engineering2014，73，： | 1 |
| 12 | Cu_(2)Sb decorated Cu nanowire arrays for selective electrocatalytic CO_(2)to CO conversion显示文摘The advancement of cost-effective and selective electrocatalyst towards CO_(2) to CO conversion is crucial for renewable energy conversion and storage,thus to achieve carbon-neutral cycle in a sustainable manner.In this communication,we report that CujSb decorated Cu nanowire arrays on Cu foil act as a highly active and selective electrocatalyst for CO_(2) to CO conversion.In CO_(2)-saturated 0.1 M KHCO_(3),it achieves a high Faraday efficiency(FE)of 86.5%for CO,at-0.90 V vs.reversible hydrogen electrode(RHE).The H_(2)/CO ratio is tunable from 0.08:1 to 5.9:1 by adjusting the potential.It is worth noting that HCOO-product was totally suppressed on such catalyst,compared with Sb counterpart.The improving selectivity for CO could be attributed to the bimetallic effect and nanowire arrays structure. | Shiyong Mou Yonghao Li Luchao Yue Jie Liang Yonglan Luo Qian Liu Tingshuai Li Siyu Lu Abdullah M.Asiri Xiaoli Xiong Dongwei Ma Xuping Sun | 2021 | Nano Research2021，14，8： | 1 |
| 13 | Facile hydrothermal and sol-gel synthesis of novel Sn-Co/C composite as superior anodes for Li-ion batteries显示文摘As an anode material in lithium ion battery,the Sn-Co/C composite electrode materials have been successfully synthesized by hydrothermal and sol-gel methods,respectively.The resultant composites were mainly composed of Sn-based oxides,nanometer Sn-Co alloy and carbon.Carbon and Co,acting as buffer materials,can accommodate to the large volume change of active Sn during the discharge-charge process,thus improving the cycling stability.Although charge/discharge curves revealed the excellent cycle performance for samples synthesized by both methods,composites obtained by the sol-gel showed a better dispersion effect of nanoparticles on the carbon matrix and possessed much more improved stable capacity with*624.9 mAh g-1over 100 cycles and that by hydrothermal method only exhibited*299.3 mAh g-1.Therefore,the Sn-Co/C composites obtained by sol-gel synthesis method could be a perfect candidate for anode material of Li-ion storage battery. | Xiaoli Zou Xianhua Hou Zhibo Cheng Yanling Huang Min Yue Shejun Hu | 2014 | Chinese Science Bulletin2014，59，23： | 1 |
| 14 | A new multi-objective bi-level programming model for energy and locality aware multi-job scheduling in cloud computing显示文摘 | Xiaoli Wang Yuping Wang Yue Cui | 2013 | Future Generation Computer Systems2013，，： | 1 |
| 15 | Temperature stable Pb(Zn1/3Nb2/3)O3-based composite ceramics prepared by particle-coating method显示文摘 | Zhenxing Yue Xiaoli Wang Liangying Zhang Xi Yao | 1997 | Journal of Materials Science Letters1997，，16： | 1 |
| 16 | Cyclic strain promotes migra- tion and proliferation of human periodontal ligament cell via PI3K signaling pathway显示文摘 | Yue H Jinsong P Xiaoli W | 2010 | Cell Mol Bioeng2010，3，4： | 1 |
| 17 | Amperometric biosensor for NADH and ethanol based on electroreduced graphene oxide–polythionine nanocomposite film显示文摘 | Zou Li Yi Huang Li Chen Xiaoli Qin Zhao Huang Yaping Zhou Yue Meng Jing Li Siyu Huang Yan Liu Wen Wang Qingji Xie Shouzhuo Yao | 2013 | Sensors & Actuators: B Chemical2013，，： | 1 |
| 18 | Dopamine receptor D 1 mediates the inhibition of dopamine on the distal colonic motility显示文摘 | Xiaohui Zhang Hua Guo Jindong Xu Yun Li Lisheng Li Xiaoli Zhang Xiaofeng Li Ruifang Fan Yue Zhang Zhongping Duan Jinxia Zhu | 2012 | Translational Research2012，，5： | 1 |
| 19 | Image reconstruction for the coded aperture system in nuclear safety and security using a Monte Carlo-based system matrix显示文摘Purpose Accurate localization of radioactive materials is critical to nuclear safety and nuclear security.A coded aperture imaging system provides a visualization solution.However,the correlation method has poor reconstruction performance for sources with low counts and for extended sources.Methods In this study,a Monte Carlo optimization-based MLEM algorithm(MC-MLEM)is proposed.The system matrix was obtained by accurate Monte Carlo simulation,so the physical effects such as mask penetration that affect the imaging process were taken into account in the MLEM algorithm.In the simulation process,the normalization of the system matrix was realized by controlling the source at different position of the source plane to have the same activity and emission angle.Results The experimental results showed that compared with the correlation method,the MC-MLEM algorithm could improve the signal-to-noise ratio and angular resolution and locate the source position quickly and accurately under low count conditions.Furthermore,the MC-MLEM algorithm could reconstruct the shape of the extended source and the expected activity ratio of cold-hot sources with large activity differences.Conclusion The MC-MLEM algorithm improved the imaging results and enhanced the reconstruction performance. | Yue Yu Xiaoli Sun Zhiming Zhang Shuangquan Liu Xiuzuo Liang Daowu Li Lei Shuai Tingting Hu Long Wei | 2023 | Radiation Detection Technology and Methods2023，7，2： | 0 |
| 20 | Linear dichroism and polarization controllable persistent spin helix in two-dimensional ferroelectric ZrOI_(2) monolayer显示文摘Two-dimensional ferroelectric(2D-FE)materials that characterize the spontaneous ferroelectricity down to monolayer limit and rich ferroic properties arising from FE orderings,have been extensively explored as low-dimensional sensor,electric and memory devices.In current work,group-IV transition metal oxide dihalide MOX_(2)(M=Zr and Hf,X=Cl,Br and I)monolayers have been identified as a new group of 2D-FE materials.Using the comprehensive first-principles calculations combined with finite temperature Monte Carlo(MC)and ab initio molecular dynamics(MD)simulations,we investigate the temperature stability of FE polarization and further uncover the unique properties associated with spontaneous ferroelectricity of MOX_(2) monolayers.In particular,ZrOI_(2) monolayer,a promising 2D-FE material with room temperature stable ferroelectricity,semiconducting electronic structure and optoelectronic response under visible light,offers an ideal material platform to investigate the coupling of intrinsic anisotropy,optical absorption selectivity and spin degree of freedom with 2D ferroelectricity.Typically,significant optical absorption anisotropy and giant linear dichroism effect are predicted for a 2D optical polarizer device based on ZrOI_(2) monolayer,where the adsorption of incident monochromatic linearly polarized light(hv=3.23 eV)along two planar directions with a nearly 100%optical selectivity can be achieved.Moreover,the spin–orbit coupling(SOC)induced spin splitting of valence band edges and out-of-plane textured spin configuration occur in ZrOI_(2) monolayer.In the meanwhile,the unidirectional spin–orbit field protected by C2v wave-vector point group can further create the persistent spin helix(PSH)state,leading to the extraordinarily long spin carrier lifetime.More importantly,the nonvolatile control of PSH state via the electric field induced polarization reversal has also been demonstrated for FE-ZrOI_(2) monolayer,which manifests as a great advantage for applications of ZrOI_(2) as the lowdimensional spin-field effect transistor and all-electric spintronics devices. | Niuzhuang Yang Gaoyang Gou Xiaoli Lu Yue Hao | 2022 | Nano Research2022，15，7： | 0 |
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