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| 1 | Effect of thermal exposure on the microstructure and creep properties of a fourth-generation Ni-based single crystal superalloy显示文摘The effect of thermal exposure on microstructure and creep properties of a fourth-generation nickelbased single crystal superalloy was investigated.The thermal exposure of samples after the full heat treatment was carried out at 1000℃,1100℃ and 1140℃ for 100 h and 200 h.The γ’ coarsening,γ’ rafting and γ channel widening were observed in samples after thermal exposure.When the thermal exposure time was constant,the morphology of γ’ phase in the alloy evolved significantly with increasing aging temperature.The interracial dislocation networks in aged samples after creep ruptured gradually became irregular and sparse with the increase of exposure temperature.When the higher exposure temperature was used,enla rgement of the defect pores was observed in samples,the microcracks were more likely to initiate and propagate at the corner of these pores.After aging at 1000℃ for 100 h,the creep life at 1140℃/137 MPa was slightly longer than that of heat-treated sample,which could be attributed to the slightly coarsened γ’ phase,homogenization of refractor elements.In contrast,the creep life of sample exposed at 1140℃ for 100 h was greatly decreased.The decrease of creep life was dominated by the rafting of γ’phase,the irregular interfacial dislocation networks as well as the enlargement of homogenization pores. | Yeshun Huang Xinguang Wang Chuanyong Cui Zihao Tan Jinguo Li Yanhong Yang Jinlai Liu Yizhou Zhou Xiaofeng Sun | 2021 | Journal of Materials Science & Technology2021，，10： | 4 |
| 2 | Effect of Plaque Composition on Biomechanical Performance of a Carotid Stent: Computational Study显示文摘Clinical application of bare metal stents is constrained by the occurrence of instent restenosis,mainly due to the complex biomechanical environment in the body.Numerical simulation method was used to evaluate the effect of plaque composition on stent performance in a carotid artery.CT angiography(CTA)data were used as a reference,and zero-load state of the carotid artery was used to establish a 3D stenotic artery model.Different plaque compositions,calcified and hypo-cellular were defined in Model 1 and Model 2,respectively.Interactions between the stents and arterial tissues within the stent crimping-expansion process were analyzed to explore the effects of plaque composition on the mechanical parameters of carotid stents.Goodman diagram and fatigue safety factor(FSF)were analyzed to explore the effects of plaque composition on fatigue performance of a carotid stent in the stent service process.In the stent crimping-expansion process,the von Mises stress in the stent and the dog-boning ratio in Model 1 were higher than that in Model 2.The calcified plaque prevented the stent from expanding the stenotic vessel to a pre-set diameter.Thus,the risk of rupture in the calcified plaque was higher than that in the hypo-cellular plaque.Plaque also affected the stress/strain in the vessel wall,which was observed to be lower in Model 1 than in Model 2.This indicated that calcified plaque could decrease the stress-induced injury of arterial tissues.Within the stent service process,the stents used in these two models were predicted to not fail under fatigue rupture as calculated by the Goodman diagram.Additionally,the points closer to the fatigue limit were generally observed at the inner bend of the stent crowns.The FSF of the stent in Model 1 was lower than that in Model 2.The stent operating in the presence of calcified plaques suffered high risk of fractures.Reliability and fatigue performance of the stent were found to be associated with plaque composition.Hence,this study may provide stent designers an approach toward enhancing the mechanical reliability of a stent. | Xinyang Cui Qingshuai Ren Zihao Li Kun Peng Gaoyang Li ZhaoyongGu Aike Qiao | 2018 | Computer Modeling in Engineering & Sciences2018，，9： | 3 |
| 3 | Multiscale Nonlinear Thermo-Mechanical Coupling Analysis of Composite Structures with Quasi-Periodic Properties显示文摘This paper reports a multiscale analysis method to predict the thermomechanical coupling performance of composite structures with quasi-periodic properties.In these material structures,the configurations are periodic,and the material coefficients are quasi-periodic,i.e.,they depend not only on the microscale information but also on the macro location.Also,a mutual interaction between displacement and temperature fields is considered in the problem,which is our particular interest in this study.The multiscale asymptotic expansions of the temperature and displacement fields are constructed and associated error estimation in nearly pointwise sense is presented.Then,a finite element-difference algorithm based on the multiscale analysis method is brought forward in detail.Finally,some numerical examples are given.And the numerical results show that the multiscale method presented in this paper is effective and reliable to study the nonlinear thermo-mechanical coupling problem of composite structures with quasiperiodic properties. | Zihao Yang Liang Ma Qiang Ma Junzhi Cui Yufeng Nie Hao Dong Xiaohong An | 2017 | Computers, Materials & Continua2017，，3： | 2 |
| 4 | Novel neutrophil extracellular trap-related mechanisms in diabetic wounds inspire a promising treatment strategy with hypoxia-challenged small extracellular vesicles显示文摘Neutrophil extracellular traps(NETs)have been considered a significant unfavorable factor for wound healing in diabetes,but the mechanisms remain unclear.The therapeutic application of small extracellular vesicles(sEVs)derived from mesenchymal stem cells(MSCs)has received considerable attention for their properties.Hypoxic preconditioning is reported to enhance the therapeutic potential of MSC-derived sEVs in regenerative medicine.Therefore,the aim of this study is to illustrate the detailed mechanism of NETs in impairment of diabetic wound healing and develop a promising NET-targeting treatment based on hypoxic pretreated MSC-derived sEVs(Hypo-sEVs).Excessive NETs were found in diabetic wounds and in high glucose(HG)-induced neutrophils.Further research showed that high concentration of NETs impaired the function of fibroblasts through activating endoplasmic reticulum(ER)stress.Hypo-sEVs efficiently promoted diabetic wound healing and reduced the excessive NET formation by transferring miR-17-5p.Bioinformatic analysis and RNA interference experiment revealed that miR-17-5p in Hypo-sEVs obstructed the NET formation by targeting TLR4/ROS/MAPK pathway.Additionally,miR-17-5p overexpression decreased NET formation and overcame NET-induced impairment in fibroblasts,similar to the effects of Hypo-sEVs.Overall,we identify a previously unrecognized NET-related mechanism in diabetic wounds and provide a promising NET-targeting strategy for wound treatment. | Ziqiang Chu Qilin Huang Kui Ma Xi Liu Wenhua Zhang Shengnan Cui Qian Wei Huanhuan Gao Wenzhi Hu Zihao Wang Sheng Meng Lige Tian Haihong Li Xiaobing Fu Cuiping Zhang | 2023 | Bioactive Materials2023，，9： | 1 |
| 5 | An outbreak of Mycobacterium marinum infection associated with handling seabass in China显示文摘To the Editor:Mycobacterium marinum is a nontuberculous mycobacterium that can cause opportunistic infections in humans,ranging from a single cutaneous lesion to disseminated disease.[1]It was first isolated from a fish in 1926 and identified as a cause of human infection in 1951.[1]The estimated annual incidence ranges from 0.04 to 0.27 per 100,000 persons in different countries.Outbreaks of M.marinum infections related to handling fish are not common,but have also been reported. | Qing Zhao Fangfang Bao Zihao Mi Zhenzhen Wang Pengcheng Huai Qing Pan Zheng Pang Yaoming Li Nan Cao Xiaotong Xue Buyan Li Xuechao Chen Jinliang Wang Yanxia Cui Wenqian Chang Yuan Zhang Zhenhua Yue Yongxia Liu Zhenhua Wang Weiguo Yan Jinyong Li Hongqing Tian Xianmei Lu Guizhi Zhou Jianjun Liu Hong Liu Furen Zhang | 2022 | Chinese Medical Journal2022，135，21： | 1 |
| 6 | Cubic H_(3)S stabilized by halogens:High-temperature superconductors at mild pressure显示文摘Superconductivity in compressed sulfur hydride(H_(3)S)at above 200 K has attracted great interest in the study of hydrogen-based superconductors.However,the pressure required to stabilize H_(3)S is 150 GPa,posing significant challenges for experiments.Therefore,it is essential to find a strategy to reduce this pressure.In this study,by introducing halogen atoms into the H-S system,we discovered that hydrogen-based superconductors of H_(6)SX(X=Cl and Br)can be dynamically stable at mild pressures(5 GPa for H_(6)SCl and H_(6)SBr),as confirmed by first-principles calculations.Through the analysis of the bond properties,we revealed that introducing halogen elements would strengthen the H–S covalent bonds to reduce the dynamically stable pressure of H_(3)S.Our study provides a scheme to reduce the superconducting pressure of hydrogen-based superconductors. | Zihao Huo Defang Duan Qiwen Jiang Zihan Zhang Tian Cui | 2023 | Science China(Physics,Mechanics & Astronomy)2023，66，11： | 0 |
| 7 | LDL receptor-related protein 1 (LRP1),a novel target for opening the blood-labyrinth barrier(BLB)显示文摘Inner ear disorders are a cluster of diseases that cause hearing loss in more than 1.5 billion people worldwide.However,the presence of the blood-labyrinth barrier(BLB)on the surface of the inner ear capillaries greatly hinders the effectiveness of systemic drugs for prevention and intervention due to the low permeability,which restricts the entry of most drug compounds from the bloodstream into the inner ear tissue.Here,we report the finding of a novel receptor,low-density lipoprotein receptor-related protein 1(LRP1),that is expressed on the BLB,as a potential target for shuttling therapeutics across this barrier.As a proof-ofconcept,we developed an LRP1-binding peptide,IETP2,and covalently conjugated a series of model small-molecule compounds to it,including potential drugs and imaging agents.All compounds were successfully delivered into the inner ear and inner ear lymph,indicating that targeting the receptor LRP1 is a promising strategy to enhance the permeability of the BLB.The discovery of the receptor LRP1 will illuminate developing strategies for crossing the BLB and for improving systemic drug delivery for inner ear disorders. | Xi Shi Zihao Wang Wei Ren Long Chen Cong Xu Menghua Li Shiyong Fan Yuru Xu Mengbing Chen Fanjun Zheng Wenyuan Zhang Xinbo Zhou Yue Zhang Shiwei Qiu Liyuan Wu Peng Zhou Xinze Lv Tianyu Cui Yuehua Qiao Hui Zhao Weiwei Guo Wei Chen Song Li Wu Zhong Jian Lin Shiming Yang | 2022 | Signal Transduction and Targeted Therapy2022，7，7： | 0 |
| 8 | Common Transceiver LIF⁃Lidar Based on Y⁃Type Optical Fiber for Marine Oil Spill Detection显示文摘This paper presents a novel laser⁃induced fluorescence(LIF)Lidar system for marine oil spilling detection.A bifurcated Y⁃type optical fiber and an optical collimating lens compose a coaxial configuration transceiver for this LIF⁃Lidar system.This LIF⁃Lidar system was further applied to measure the excitation spectra from floating oil slicks with different thicknesses on top of seawater at different distances.The system presents several advantages such as compact structure,stable optical path,and convenient operation,which offers a wide application prospect in ocean exploration. | Zongjie Bi Songlin Yin Yanchao Zhang Zihao Cui Zhaoshuo Tian Shiyou Fu | 2021 | Journal of Harbin Institute of Technology(New Series)2021，28，5： | 0 |
| 9 | Weighting Function Modification Used for Phase Transform-Based Time Delay Estimation显示文摘Generalized cross-correlation is considered as the most straightforward time delay estimation algorithm.Depending on various weighting function,different methods were derived and a straightforward method,named phase transform(PHAT)has been widely used.PHAT is well-known for its robustness to reverberation and its sensitivity to noise,which is partly due to the fact that PHAT distributes same weights to the frequencies dominated by signal or noise.To alleviate this problem,two weighting functions are proposed in this paper.By taking a posteriori signal-to-noise ratio(SNR)into account to classify reliable and unreliable frequencies,different weights could be assigned.The first proposed weighting function borrows the idea of binary mask and distributes same weights to frequencies in same set,whereas,the second one assigns weights based on coherence function.Experiments showed the robustness of proposed methods to reverberation and noise for improving the performance of time delay estimation through various criteria. | Xue Yang Changchun Bao Zihao Cui | 2022 | China Communications2022，19，11： | 0 |
| 10 | Determination of Double Beta Decay Half-Life of 136Xe with the PandaX-4T Natural Xenon Detector显示文摘Precise measurement of two-neutrino double beta decay(DBD)half-life is an important step for the searches of Majorana neutrinos with neutrinoless double beta decay.We report the measurement of DBD half-life of 136xe using the Pandax-4T dual-phase Time Projection Chamber(TPC)with 3.7-tonne natural xenon and the first 94.9-day physics data release. | Lin Si Zhaokan Cheng Abdusalam Abdukerim Zihao Bo Wei Chen Xun Chen Yunhua Chen Chen Cheng Yunshan Cheng Xiangyi Cui Yingjie Fan Deqing Fang Changbo Fu Mengting Fu Lisheng Geng Karl Giboni Linhui Gu Xuyuan Guo Ke Han Changda He Jinrong He Di Huang Yanlin Huang Zhou Huang Ruquan Hou Xiangdong Ji Yonglin Ju Chenxiang Li Jiafu Li Mingchuan Li Shu Li Shuaijie Li Qing Lin Jianglai Liu Xiaoying Lu Lingyin Luo Yunyang Luo Wenbo Ma Yugang Ma Yujun Mao Yue Meng Nasir Shaheed Xiaofeng Shang Xuyang Ning Ningchun Qi Zhicheng Qian Xiangxiang Ren Changsong Shang Guofang Shen Wenliang Sun Andi Tan Yi Tao Anqing Wang Meng Wang Qiuhong Wang Shaobo Wang Siguang Wang Wei Wang Xiuli Wang Zhou Wang Yuehuan Wei Mengmeng Wu Weihao Wu Jingkai Xia Mengjiao Xiao Xiang Xiao Pengwei Xie Binbin Yan Xiyu Yan Yong Yang Chunxu Yu Jumin Yuan Ying Yuan Zhe Yuan Dan Zhang Minzhen Zhang Peng Zhang Shibo Zhang Shu Zhang Tao Zhang Li Zhao Qibin Zheng Jifang Zhou Ning Zhou Xiaopeng Zhou Yong Zhou | 2023 | Research2023，，2： | 0 |
| 11 | Intrinsic emission and tunable phosphorescence of perfluorosulfonate ionomers with evolved ionic clusters显示文摘Intrinsic emission from unorthodox luminogens without traditional conjugated building blocks is drawing increasing attention.However,the emission mechanism is still controversial.Herein,we demonstrate the intriguing emission from perfluorosulfonate ionomers(PFSIs),which can be explained by the clustering triggered emission(CTE)mechanism.Despite being free of any conventional chromophores,PFSIs exhibit bright emission and multi-color phosphorescence(77 K)in concentrated solutions,powders and membranes with obvious aggregation-induced emission(AIE)characteristics.Clustered sulfonic acids are responsible for the light emission,and their connection and evolution are deeply explored via X-ray diffraction(XRD)and small angel X-ray scattering(SAXS),in which the electron overlap determined by the clustered status results in the extended conjugation and simultaneously rigidified conformations.These results demonstrate that it is feasible to use fluorescence analysis to explore the ionic cluster structure and evolution of PFSI,and it can be applied in the pure organic luminescent field as well. | Qing Zhou Jia Cui Tianjia Yang Changlu Hu Zihao Zhong Zhenhua Sun Yongyang Gong Supeng Pei Yongming Zhang | 2020 | Science China Chemistry2020，63，6： | 0 |
| 12 | An Efficient Multilevel Threshold Image Segmentation Method for COVID-19 Imaging Using Q-Learning Based Golden Jackal Optimization显示文摘From the end of 2019 until now,the Coronavirus Disease 2019(COVID-19)has been rampaging around the world,posing a great threat to people's lives and health,as well as a serious impact on economic development.Considering the severely infectious nature of COVID-19,the diagnosis of COVID-19 has become crucial.Identification through the use of Computed Tomography(CT)images is an efficient and quick means.Therefore,scientific researchers have proposed numerous segmentation methods to improve the diagnosis of CT images.In this paper,we propose a reinforcement learning-based golden jackal optimization algorithm,which is named QLGJO,to segment CT images in furtherance of the diagnosis of COVID-19.Reinforcement learning is combined for the first time with meta-heuristics in segmentation problem.This strategy can effectively overcome the disadvantage that the original algorithm tends to fall into local optimum.In addition,one hybrid model and three different mutation strategies were applied to the update part of the algorithm in order to enrich the diversity of the population.Two experiments were carried out to test the performance of the proposed algorithm.First,compare QLGJO with other advanced meta-heuristics using the IEEE CEC2022 benchmark functions.Secondly,QLGJO was experimentally evaluated on CT images of COVID-19 using the Otsu method and compared with several well-known meta-heuristics.It is shown that QLGJO is very competitive in benchmark function and image segmentation experiments compared with other advanced meta-heuristics.Furthermore,the source code of the QLGJO is publicly available at https://github.com/Vang-z/QLGJO. | Zihao Wang Yuanbin Mo Mingyue Cui | 2023 | Journal of Bionic Engineering2023，20，5： | 0 |
| 13 | Insights into interfacial speciation and deposition morphology evolution at Mg-electrolyte interfaces under practical conditions显示文摘Rechargeable magnesium(Mg)battery technologies show the promise of low cost,less safety concerns and relatively higher energy density.Interrogating the critical issues on the Mg stripping/plating performance as well as the Mg metal anode-electrolyte interfacial chemistry is one great importance under the practical areal capacity and rate conditions.In this work,we systematically investigate the electrochemistry of Mg stripping/plating processes within four distinctive Mg-ion electrolytes and the Mg anodeelectrolyte interfacial chemistry under practical conditions.Electrochemical results show that the cycle life of Mg//Cu asymmetric cells using these above electrolytes is significantly shortened(less than 10 cycles)when tested at a practical areal capacity of 10 mAh cm^-2.Further optical and electron microscopic analyses reveal that the gradual growth of the Mg deposits is susceptible to detachment from the copper substrate,where the initial nucleation process might occur.In spite of showing an interconnected particle-like morphology,the Mg deposits could easily penetrate the porous separator,leading to cell failure.The co-deposition of metallic Al is revealed from surface region to bulk,while the Cl-containing species exist in the near surface of Mg deposits.Our work not only highlights the critical impacts of areal capacity on the performances of Mg stripping/plating process,but calls for further efforts to eliminating the safety concerns of Mg anode under practical conditions. | Zihao Song Zhonghua Zhang Aobing Du Shamu Dong Guicun Li Guanglei Cui | 2020 | Journal of Energy Chemistry2020，29，9： | 0 |
| 14 | Dynamic thermo-mechanical coupled simulation of statistically inhomogeneous materials by statistical second-order two-scale method显示文摘In this paper,a statistical second-order twoscale(SSOTS) method is developed to simulate the dynamic thcrmo-mechanical performances of the statistically inhomogeneous materials.For this kind of composite material,the random distribution characteristics of particles,including the shape,size,orientation,spatial location,and volume fractions,are all considered.Firstly,the repre.sentation for the microscopic configuration of the statistically inhomogeneous materials is described.Secondly,the SSOTS formulation for the dynamic thermo-mechanical coupled problem is proposed in a constructive way,including the cell problems,effective thermal and mechanical parameters,homogenized problems,and the SSOTS formulas of the temperatures,displacements,heat flux densities and stresses.And then the algorithm procedure corresponding to the SSOTS method is brought forward.The numerical results obtained by using the SSOTS algorithm are compared with those by classical methods.In addition,the thermo-mechanical coupling effect is studied by comparing the results of coupled case with those of uncoupled case.It demonstrates that the coupling effect on the temperatures,heat flux densities,displacements,and stresses is very distinct.The results show that the SSOTS method is valid to predict the dynamic thermo-mechanical coupled performances of statistically inhomogeneous materials. | Zihao Yang Junzhi Cui Yufeng Nie Zhiqiang Huang Meizhen Xiang | 2015 | Acta Mechanica Sinica2015，31，5： | 0 |
| 15 | Controllable Polymerization of N-Substituted β-Alanine N-Thiocarboxyanhydrides for Convenient Synthesis of Functional Poly(β-peptoid)s显示文摘Poly(β-peptoid)is a class of polypeptide mimics that possesses excellent biocompatibility and resistance to proteolysis.However,the synthesis of poly(β-peptoid)s with functionalities is a long-standing challenge that greatly hinders the functional study and application of poly(β-peptoid)s.We report a controllable and easy synthesis of poly(β-peptoid)s bearing diverse functionalities via the ring-opening polymerization on N-substitutedβ-alanine N-thiocarboxyanhydrides(β-NNTAs).The polymerization can be carried out in openvesselsundermildconditions usingaminesas the initiators to provide poly(β-peptoid)s with targeted molecular weights,narrow dispersities,and diverse functionalities in the side chains and termini.Theβ-NNTAs polymerization is even compatible with initiators bearing unprotected hydroxyl groups.The amphiphilic/cationic poly(β-peptoid)s exhibit a broad spectrum and potent antibacterial activities against multidrug-resistant bacteria.In addition,the highly favored stability ofβ-NNTAmonomers for purification and storage highlights the advantages of thisβ-NNTA polymerization strategy for poly(β-peptoid)s synthesis,functional study,and application as a synthetic mimic of polypeptides. | Ximian Xiao Min Zhou Zihao Cong Longqiang Liu Jingcheng Zou Zhemin Ji Ruxin Cui Yueming Wu Haodong Zhang Sheng Chen Maoquan Li Runhui Liu | 2023 | CCS Chemistry2023，5，4： | 0 |
| 16 | First-principles study on the conventional superconductivity of N-doped fcc-LuH_(3)显示文摘Recently,room-temperature superconductivity has been reported in a nitrogen-doped lutetium hydride at near-ambient pressure[Dasenbrock-Gammon et al.,Nature 615,244(2023)].The superconducting properties might arise from Fm3m-LuH_(3)−δNε.Here,we systematically study the phase diagram of Lu–N–H at 1 GPa using first-principles calculations,and we do not find any thermodynamically stable ternary compounds.In addition,we calculate the dynamic stability and superconducting properties of N-doped Fm3m-LuH_(3) using the virtual crystal approximation(VCA)and the supercell method.The R3m-Lu_(2)H_(5)N predicted using the supercell method could be dynamically stable at 50 GPa,with a T_(c) of 27 K.According to the VCA method,the highest T_(c) is 22 K,obtained with 1%N-doping at 30 GPa.Moreover,the doping of nitrogen atoms into Fm3m-LuH_(3) slightly enhances T_(c),but raises the dynamically stable pressure.Our theoretical results show that the T_(c) values of N-doped LuH_(3) estimated using the Allen–Dynes-modified McMillan equation are much lower than room temperature. | Zihao Huo Defang Duan Tiancheng Ma Zihan Zhang Qiwen Jiang Decheng An Hao Song Fubo Tian Tian Cui | 2023 | Matter and Radiation at Extremes2023，8，3： | 0 |
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