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| 1 | Spatial variations of macrozoobenthos and sediment nutrients in Lake Yangcheng: Emphasis on effect of pen culture of Chinese mitten crab显示文摘We determined the effect of Chinese mitten crab(CMC) pen culture on the quantified spatial distribution of the macrozoobenthic community and sediment nutrients in Lake Yangcheng.Redundancy analysis indicated that water temperature, macrophyte occurrence, sediment type, and crab culture were the main environmental factors that influence the spatiotemporal macrozoobenthic distribution. Macrozoobenthic assemblages in the lake were characterized by eutrophic indicator species. In the most polluted estuaries, the abundance and diversity indices of the whole community and abundance of chironomids and oligochaetes were significantly depressed, and sediment carbon(C) and phosphorus(P) were significantly enhanced compared with those in the western, middle(MB), and eastern basin(EB). Crab culture in this lake had significant effects on the species composition of the macrozoobenthic community in one of three CMC culture pens(CP), and generally depressed the abundance of most chironomid and oligochaete species. Significantly increased diversity, evenness, sediment carbon and nitrogen content, and sediment C:P ratio in the CP were found compared with those in the three basins.However, no conspicuous difference in sediment P content between the CP and the two basins of MB and EB was detected. Our results showed that the enhanced diversity and evenness of macrozoobenthos might be associated with the joint effect of macrophyte planting and crab predation, and macrophyte planting may modify the effects of CMC culture by leading to disproportional accumulation of C and N in the sediment relative to P in the CP of the lake. | Liping Chen Ying Zhang Qigen Liu Zhongjun Hu Yuejuan Sun Ziran Peng Lijing Chen | 2015 | Journal of Environmental Sciences2015，27，11： | 15 |
| 2 | Novel synthesis of fly-ash-derived Cu-loaded SAPO-34 catalysts and their use in selective catalytic reduction of NO with NH3显示文摘A combined acid–alkali hydrothermal method was used to prepare fly ash–derived SAPO-34 molecular sieves from a thermal power plant in Inner Mongolia(China).The specific surface area of the prepared fly-ash-derived SAPO-34 molecular sieves was 579 m^2 g^-1,the total pore volume was about 0.27 cm^3 g^-1,and the pore size was 0.56 nm;the molar ratios of Al2O3:P2O5:SiO2 were 1:0.86:0.45.Cu/SAPO-34 catalysts were prepared by impregnation of low-cost fly-ash-derived SAPO-34 molecular sieves as a support and tested in selective catalytic reduction with NH3(NH3-SCR).Powder X-ray diffraction(XRD),N2 adsorption–desorption,X-ray photoelectron spectroscopy(XPS),H2 temperatureprogrammed reduction(H2-TPR),NH3 temperature-programmed desorption(NH3-TPD),electron paramagnetic resonance(EPR),nuclear magnetic resonance(NMR),X-ray fluorescence analysis(XRF)and scanning electron microscopy(SEM)were used for catalyst characterization and investigation of the relationships between the catalyst structure and the catalytic activity.The actual silica:alumina ratio of the molecular sieves did not increase with increasing Cu loading,indicating that increasing the Cu loading does not change the original structure of the SAPO-34 molecular sieves.The XRF and NMR results showed that replacement by Cu results in more Si islands.The molecular sieve acidity decreased because of the increased number of Si islands.The NH3-TPD results showed that for the Cu/SAPO-34 catalysts there was a low correlation between the low-temperature activity and the amount of acidic sites.SCR activity is closely related to the location of Cu.The 4.47 Cu/SAPO-34 catalyst has the highest isolated Cu2+showed the highest NH3-SCR activities(>90%)at 250–350℃.This work opens up new avenues for recycling fly ash formed in coal-fired power plants(reducing environmental pollution)and developing low-cost SCR catalysts for NOx pollution control. | Ge Li Baodong Wang Qi Sun Wayne Qiang Xu Ziran Ma Hongyan Wang Daojun Zhang Jiali Zhou | 2019 | Green Energy & Environment2019，4，4： | 6 |
| 3 | Imbalance of the reciprocally inhibitory loop between the ubiquitin-specific protease USP43 and EGFR/PI3K/AKT drives breast carcinogenesis显示文摘 | Lin He Xinhua Liu Jianguo Yang Wanjin Li Shumeng Liu Xujun Liu Ziran Yang Jie Ren Yue Wang Lin Shan Chengjian Guan Fei Pei Liandi Lei Yu Zhang Xia Yi Xiaohan Yang Jing Liang Rong Liu Luyang Sun Yongfeng Shang | 2018 | Cell Research2018，28，9： | 5 |
| 4 | Liquid-liquid phase separation in human health and diseases显示文摘Emerging evidence suggests that liquid-liquid phase separation(LLPS)represents a vital and ubiquitous phenomenon underlying the formation of membraneless organelles in eukaryotic cells(also known as biomolecular condensates or droplets).Recent studies have revealed evidences that indicate that LLPS plays a vital role in human health and diseases.In this review,we describe our current understanding of LLPS and summarize its physiological functions.We further describe the role of LLPS in the development of human diseases.Additionally,we review the recently developed methods for studying LLPS.Although LLPS research is in its infancy-but is fast-growing-it is clear that LLPS plays an essential role in the development of pathophysiological conditions.This highlights the need for an overview of the recent advances in the field to translate our current knowledge regarding LLPS into therapeutic discoveries. | Bin Wang Lei Zhang Tong Dai Ziran Qin Huasong Lu Long Zhang Fangfang Zhou | 2021 | Signal Transduction and Targeted Therapy2021，6，9： | 4 |
| 5 | Hot deformation behavior of FGH96 superalloys显示文摘The hot deformation behavior of FGH96 superalloys at 1070-1170°C and 5×10?4-2×10?1 s?1 were investigated by means of the isothermal compression tests at a Gleeble-1500 thermal mechanical simulator. The results show that dynamic recovery acts as the main softening mechanism below 2×10?3 s?1, whereas dynamic recrystallization acts as the main softening mechanism above 2×10?3 s?1 during deformation; the temperature increase caused by the deformation and the corresponding softening stress is negligible; the thermal-mechanical constitutive model to describe the hot deformation behavior is given, and the value of the apparent deformation activation energy (Qdef ) is determined to be 354.93 kJ/mol. | Jiantao Liu Guoquan Liu Benfu Hu Yuepeng Song Ziran Qin Yiwen Zhang | 2006 | Journal of University of Science and Technology Beijing2006，13，4： | 4 |
| 6 | Alterations in microbiota of patients with COVID-19:potential mechanisms and therapeutic interventions显示文摘The global coronavirus disease 2019(COVID-19)pandemic is currently ongoing.It is caused by severe acute respiratory syndrome coronavirus 2(SARS-CoV-2).A high proportion of COVID-19 patients exhibit gastrointestinal manifestations such as diarrhea,nausea,or vomiting.Moreover,the respiratory and gastrointestinal tracts are the primary habitats of human microbiota and targets for SARS-CoV-2 infection as they express angiotensin-converting enzyme-2(ACE2)and transmembrane protease serine 2(TMPRSS2)at high levels.There is accumulating evidence that the microbiota are significantly altered in patients with COVID-19 and post-acute COVID-19 syndrome(PACS). | Bin Wang Lei Zhang Yongqiang Wang Tong Dai Ziran Qin Fangfang Zhou Long Zhang | 2022 | Signal Transduction and Targeted Therapy2022，7，5： | 3 |
| 7 | More permutation polynomials with differential uniformity six显示文摘Differential analysis is one of the most important attacks threatening iterated block ciphers.To resist against differential attacks[1],the multioutput Boolean functions used in designing Sboxes should have low differential uniformity.For a positive integer n,the lowest differential uniformity of the functions from the finite field F_(2n)(for a prime power q,F_q denotes the finite field | Ziran TU Xiangyong ZENG Zhiyong ZHANG | 2018 | Science China(Information Sciences)2018，61，3： | 3 |
| 8 | Molecular analysis of cell-free DNA identifies distinct molecular features in patients with chemosensitive and chemorefractory small cell lung cancer显示文摘Dear Editor,Lung cancer is the predominant cause of cancer-related death worldwide[1].Non-small cell lung cancer accounts for 80%-85%and small cell lung cancer(SCLC)accounts for 15%-20%of all lung cancer cases[2].Patients with SCLC,a highly aggressive and poorly differentiated malignancy,have an alarming average 5-year overall sur-vival rate of less than 10%[3].Most patients with SCLC already show clinically detectable metastases at diag-nosis and have extremely poor prognoses,even when treated with multimodality therapy[4].Before the addi-tion of atezolizumab to chemotherapy became the first-line treatment of extensive-stage SCLC,chemotherapy is the primary treatment of SCLC[5]. | Jie Zhang Chen Tian Fang Lv Jianfei Wang Wenbo Han Jun Nie Ling Dai Weiheng Hu Xiaoling Chen Xiangjuan Ma Guangming Tian Di Wu Sen Han Yang Wang Jieran Long Ziran Zhang Jian Fang Henghui Zhang | 2019 | Cancer Communications2019，39，1： | 2 |
| 9 | Primary murine limb bud mesenchymal cells in long-term culture complete chondrocyte differentiation:TGF-beta delays hypertrophy and PGE2 inhibits terminal differentiation显示文摘 | Zhang X Ziran N Goater JJ | 2004 | Bone2004，34，5： | 1 |
| 10 | Primary murine limb bud mesenchymal cells in long-term culture complete chondrocyte differentiation:TGF-beta delays hypertrophy and PGE2 inhibits terminal differentiation显示文摘 | Zhang X Ziran N Goater JJ Schwarz EM Puzas JE Rosier RN Zuscik M Drissi H O'Keefe RJ | | 0，，： | 1 |
| 11 | Effect of manganese and/or ceria loading on V_2O_5-MoO_3/TiO_2 NH_3 selective catalytic reduction catalyst显示文摘The effect of manganese and/or ceria loading of V2 O5-MoO3/TiO2 catalysts was investigated for selective catalytic reduction(SCR) of NOx by NH3.The manganese and/or ceria loaded V2 O5-MoO3/TiO2 catalysts we re prepared by the wetness impregnation method.The physicochemical characteristics of the catalysts were thoroughly characterized.The catalytic performance of 1.5 wt% V2 O5-3 wt% MoO3/TiO2(V1.5 Mo3/Ti) is greatly enhanced by addition of 2.5 wt% MnOx and 3.0 wt% CeO2(V1.5 Mo3 Mn2.5 Ce3/Ti) below450℃.Compared with the V1.5 Mo3/Ti catalyst with NOx conversion of 75% at 275 ℃,V1.5 Mo3 Mn2.5 Ce3/Ti exhibits higher NOx conversion of 84% with good resistance to SO2 and H2 O at a gas hourly space velocity value of 150000 h-1.The active manganese,cerium,molybdenum,and vanadium oxide species are highly dispersed on the catalyst surface and some synergistic effects exist among these species.Addition of MnOx significantly enhances the redox ability of the cerium,vanadium,and molybdenum species.Addition of Ce increases the acidity of the catalyst.More active oxygen species,including surface chemisorbed oxygen,form with addition of Mn and/or Ce.Because of the synergistic effects,appropriate proportions of manganese in different valence states exist in the catalysts.In summary,the good redox ability and the strong acidity contribute to the high NH3-SCR activity and N2 selectivity of the V1.5 Mo3 Mn2.5 Ce3/Ti catalyst in a wide temperature range.And the V1.5 Mo3 Mn2.5 Ce3/Ti catalyst shows good resistance to H2 O and SO2 in long-time catalytic testing,which can be ascribed to the highly sulfated species adsorbed on the catalyst. | Daojun Zhang Ziran Ma Baodong Wang Tao Zhu Duan Weng Xiaodong Wu Jingyun Chen Hongyan Wang Ge Li Jiali Zhou | 2020 | Journal of Rare Earths2020，38，7： | 1 |
| 12 | Primary murine limb bud mesenchymal cells in long-term culture complete chondrocyte differentiation:TGF-beta delays hypertrophy and PGE2 inhibits terminal differentiation显示文摘 | Zhang X Ziran N Goater JJ | 2004 | Bone2004，34，5： | 1 |
| 13 | Modularly engineered prodrug-nanoassemblies for cancer therapy:Nonpharmacological moiety dominating delivery fates显示文摘Self-engineered small-molecule prodrug-nanoassemblies have emerged as promising nanomedicines for cancer treatment.Modular design of prodrug molecules is crucial to guarantee the favorable assembly stability,tumor-specific prodrug activation,and satisfactory antitumor effect.However,too much attention has been paid to the pharmacophores and chemical linkages in prodrug molecules while neglects the vital roles of nonpharmacological moieties.Herein,we found that iso-carbon fatty acids with different number,position,and cis-trans configuration of double bonds dramatically affect the nanoassembly feature and drug delivery fates of thioether-linked paclitaxel prodrug-nanoassemblies.Particularly,the number and cis-trans configuration of double bonds in fatty acid moieties not only dominate the self-assembly ability and colloidal stability of prodrugs,but also exert significant influences on the pharmacokinetics,prodrug activation,and antitumor activity of prodrug-nanoassemblies.Finally,oleic acid with one cis double bond stands out as the optimal nonpharmacological moiety for thioether-linked paclitaxel prodrugnanoassemblies.This study elucidates the crucial roles of nonpharmacological moieties in prodrugs,and provides new insights into the modular design of prodrug-based nanomedicines for cancer therapy. | Yuequan Wang Qian Qiu Rui Liao Xinhui Wang Ziran Zhou Xuanbo Zhang Haotian Zhang Zhonggui He Shenwu Zhang Cong Luo Jin Sun | 2023 | Nano Research2023，16，1： | 0 |
| 14 | Comparing mineral weathering and elemental transport between earth's critical zone with different parent rocks in Yanshan Mountain,Hebei province,China显示文摘Bedrock weathering performs a significant influence on the evolution of Earth’s critical zone.Carbonate rock(dolostone),metamorphic rock(gneiss),and sedimentary rock(sandstone)geological formations in Yanshan Mountain,Hebei Province,are taken as objects to probe the controlling of geological formations on weathering characteristics,migration,and enrichment of elements as well as structure of Earth’s critical zone under the identical climate conditions through geological field survey,analysis on minerals component,element distribution in the weathering profile.The dolostone geological formation(DGF)is lithologically dominated by dolostone,characterized by the strongest and predominant chemical weathering.During bedrock weathering and pedogenesis,DGF is marked by significant depletion of CaO,Mg O,S,Mn,Mo and enrichment of N,K,Fe_(2)O_(3),and Zn with concentrations of P,Cu,and B keeping stable.Shortage of soil-forming materials and significant loss are driven by soil erosion,which results in thin regolith and soil.The soil thickness is less than 10 cm,and the regolith thickness is less than 30 cm.The vegetation community is predominantly rock arbor or brush,which is calcivorous and tolerant of barrenness.Plagiogneiss is a dominant rock type of gneiss geological formation(GGF),characterized by the weakest weathering and fast chemical and physical weathering rate.GGF is masked by significant depletion of P,K,CaO,MgO,Fe_(2)O_(3),Mn,Cu and enrichment of N,S,Mo,and B,with contents of Zn keeping stable.Both soil and regolith developed in GGF are relatively thick for one of the reasons that biotite expands during weathering.The soil thickness is more than 50 cm,and the regolith thickness ranges from 100 to 200 cm.The vegetation community is predominantly high-quality economic forests and various arbors because of the enrichment of nutrients in GGF.Sandstone is primarily a rock type of sandstone geological formation(SGF),characterized by moderate weathering degree and slow chemical weathering rate.SGF is marked by significant depletion of P,K,CaO,MgO,Fe_(2)O_(3),and enrichment of N,S,Mn,Cu,Zn,and Mo,with fluctuant changes of Zn and B.The thickness of soil developed in SGF varies between that of DGF and GGF.The soil thickness ranges from 30 to 50 cm,and the regolith thickness ranges from 50 to 100 cm.Chinese pines are widely spread on the shady slopes of SGF.Research provides theoretical support for screening dominant ecological resource areas,ecological industry development and ecological protection and restoration for Yanshan Mountain,Hebei Province. | Zijian Sun Zhen Liao Wei Shen Daqing Fu Xiaofeng Wei Huiqiong Zhang Ziran Chen Lianghui Xiong Tianhao An Hao Wei | 2022 | Acta Geochimica2022，41，6： | 0 |
| 15 | Application of MIGP in Phosphate Rock Districts Development Planning and System Economic Evaluation | ZHOU Xuejun, ZHONG Ziran, CHEN Bingyan, ZHOU Qiumo, GUI Jingshe,ZHU Guangshu, ZHANG Xinqiang and CHEN Shaohui Institute of Planning and Design for Chemical Mines, Ministry of Chemical Industry | 1992 | Systems Science and Systems Engineering1992，2，1： | 0 |
| 16 | Establishment of enzyme-linked immunosorbent assay for beef and lamb contents in cooked meat显示文摘In this study,an enzyme 1linked immunosorbent assay(ELISA)was established to detect beef and 1amb components,and its performance was tested.Double-antibody sandwich ELISA was adopted and determined a coating concentration of capture antibody 3G5 of 1:4000,a working concentration of enzyme-labeled antibody 2E7-horseradish peroxidase(HRP)of 1:1000,a sample incubation time of 60 min and a detection antibody reaction time of 60 min.The specificity,sensitivity,repeatability and stability of this assay were detemmined.The limit of detection for beef and 1amb skeleta1 muscle troponin I was 45 mg/kg,the inter-assay and intra-assay recovery rates ranged from 80.4%to 115.7%,the coefficients of variation were below 13.6%,and the cIoss reaction rates of the tissue components of chicken,duck and fish were below 13.4%.The sandwich ELISA method established in this study is stable and has high accuracy.The test results were consistent with the polymerase chain reaction(PCR)method at 50 and 100 g/kg-Therefore,this ELISA method can be used to quantitatively detect beef and 1amb components in meat products. | Yujing Li Jingjing Liu Sufang Fan Li Zhao Jing Zhang Erjing Zhang Ziran Li Yan Zhang Chunsheng Li | 2024 | Journal of Future Foods2024，4，1： | 0 |
| 17 | TFP and labor productivity:empirical facts of China’s macro-economy and issues for long-run economic growth显示文摘The empirical facts of China’s Macro-economy from 2013 to 2014 show the rate of investment and scale of import and export are approaching a maximum and there is an increasing fluctuation in investment and trade;deflation in real economy and the real estate market bubble go hand in hand;and efficiency imbalances between industries and regions become acute.The phase of growth driven by investment and wealth is approaching its end and the economy has entered a crucial period of structural adjustment.The economic growth rate is anticipated to be 7.4%in 2014,and stand between 6.4%and 7.8%over the next five years.Steady growth and high efficiency become the new requirements during the slowing-down of economic growth.In the process of investment-driven growth transforming into efficiency-driven growth,it is well worth paying attention to the establishment of a long-term mechanism for consumption-driven growth.The balance between investment and consumption in the sense of demand management is rendered unhelpful to establishing a path for sustainable growth in China;the report aims to deliver a new perspective by pondering the dynamic efficiency of consumption in the transformation of investment potential into consumption-driven growth. | Research Group of Cutting-edge Study on China’s Economic Growth Yuan Fuhua Zhang Ziran Zhang Ping Liu Xiahui | 2014 | China Finance and Economic Review2014，3，4： | 0 |
| 18 | Parallel Processing Design for LTE PUSCH Demodulation and Decoding Based on Multi-Core Processor显示文摘The Long Term Evolution (LTE) system imposes high requirements for dispatching delay.Moreover,very large air interface rate of LTE requires good processing capability for the devices processing the baseband signals.Consequently,the single-core processor cannot meet the requirements of LTE system.This paper analyzes how to use multi-core processors to achieve parallel processing of uplink demodulation and decoding in LTE systems and designs an approach to parallel processing.The test results prove that this approach works quite well. | Zhang Ziran,Li Jun,Li Changxiao(ZTE Corporation,Shenzhen 518057,P.R.China) | 2009 | ZTE Communications2009，7，1： | 0 |
| 19 | Co_(3)O_(4)-ZnO/rGO catalyst preparation and rhodamine B degradation by sulfate radical photocatalysis显示文摘The development of a combined photocatalytic system with peroxymonosulfate (PMS) has great potential applications in the degradation and treatment of aqueous organic pollutants. Herein, a Co_(3)O_(4)-ZnO/rGO was prepared by a hydrothermal method using cobalt acetate, zinc acetate, and reduced graphene oxide (rGO) as the main raw materials. The physical and chemical characteristics of the obtained catalyst were analyzed using X-ray diffraction (XRD), X-ray photoelectron spectroscopy (XPS),scanning electron microscopy (SEM), and Fourier transform infrared (FT-IR). The photocatalytic features and capacities of the catalytic materials to activate PMS were investigated. Co_(3)O_(4)-ZnO/rGO exhibited stronger photocatalytic activity and ability to activate PMS than Co_(3)O_(4)/rGO or ZnO/rGO, and significantly improved the ability of PMS and photocatalysis to synergistically degrade rhodamine B (RhB), with a degradation rate of 90.40% within 40 min. The mechanism of RhB degradation was proposed based on characterization of materials, evaluation of RhB degradation efficiency, and analysis of the active species involved. The unique particle/sheet structure of Co_(3)O_(4)-ZnO/rGO provides a large number of active sites, and the formation of heterojunctions between Co_(3)O_(4) and ZnO improves carrier separation and transport in the reaction system. Our study offers a reference for designing more effective heterojunction catalysts based on the combination of PMS and photocatalytic technology. | Zhanmei ZHANG Yi ZHANG Xilin CHEN Ziran HUANG Zuqin ZOU Huaili ZHENG | 2023 | Journal of Zhejiang University-Science A(Applied Physics & Engineering)2023，24，8： | 0 |
| 20 | Genome-wide selection and introgression of Chinese rice varieties during breeding显示文摘China is the largest rice-producing country,but the genomic landscape of rice diversity has not yet been clarified.In this study,we re-sequence 1070 rice varieties collected from China(400)and other regions in Asia(670).Among the six major rice groups(aus,indica-I,indica-II,aromatic,temperate japonica,and tropical japonica),almost all Chinese varieties belong to the indica-II or temperate japonica group.Most Chinese indica varieties belong to indica-II,which consists of two subgroups developed during different phases of rice breeding.The genomic segments underlying the differences between these subgroups span36.32 Mb.The Chinese japonica rice varieties fall into the temperate japonica group,consisting of two subgroups based on their geographical distribution.The genomic segments underlying the differences between these subgroups span 27.69 Mb.These differentiated segments in the Chinese indica varieties span 45 genes with nonsynonymous mutations that are closely related to variations in plant height and grain width.Fifty-four genes with nonsynonymous mutations are associated with the differences in heading date between the two Chinese japonica subgroups.These findings provide new insights into rice diversity in China that will facilitate the molecular breeding. | Jinyue Ge Junrui Wang Hongbo Pang Fei Li Danjing Lou Weiya Fan Ziran Liu Jiaqi Li Danting Li Baoxuan Nong Zongqiong Zhang Yanyan Wang Jingfen Huang Meng Xing Yamin Nie Xiaorong Xiao Fan Zhang Wensheng Wang Jianlong Xu Sung Ryul Kim Ajay Kohli Guoyou Ye Weihua Qiao Qingwen Yang Xiaoming Zheng | 2022 | Journal of Genetics and Genomics2022，49，5： | 0 |
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