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| 1 | Structure and coalbed methane occurrence in tectonically deformed coals显示文摘Research on structure of tectonically deformed coals(TDC) is a key issue in coal and gas outburst prevention and coalbed methane(CBM) exploitation.This paper presents a summary on the research progress in TDC's structural-genetic classification,tectonic strain influence on coal microstructure,coal porosity system,coal chemical structure and constituents,and their relationship with the excess coalbed methane.Previous studies suggested that tectonic deformation had significant influence on coal microstructure,coal super microstructure,and even chemical macromolecular structure.The main mechanisms of coal deformation are the tectonic stress degradation and polycondensation metamorphism(dynamical metamorphism).Besides,under different deformation mechanisms,the ultra-and micro-structure and chemical constituents of TDC presented distinct characteristics.Based on these achievements,we propose one possible evolutionary trend of TDC with different deformation mechanisms,and suggest that the coal and gas outburst in the TDC,especially in the mylonitic coals,may be not only controlled by geological structure,but also influenced by the tectonic stress degradation of ductile deformation.Therefore,further study on TDC should be focused on the controlling mechanism of deformation on structure and composition of coal,generation conditions and occurrence state of excess coalbed methane from deformation mechanism of coal. | HOU QuanLin LI HuiJun FAN JunJia JU YiWen WANG TianKai LI XiaoShi WU YuDong | 2012 | Science China Earth Sciences2012，55，11： | 49 |
| 2 | Chronic hepatitis B virus infection: epidemiology, prevention, and treatment in China显示文摘长期的肝炎 B 是在中国的一个主要健康问题。自从 1992,通用种痘节目在中国改变了肝炎 B 病毒感染的传染病学从高度到中等地方性。在中国的最流行的肝炎 B 病毒种类是遗传型 B 和 C,而在西方的省的那些是遗传型 D 和 C/D 混血儿。长期的肝炎 B 在中国提出重担到社会。不同治疗策略被探索了以一种划算的方式改进耐心的结果。然而,因为通常低的收入和有限资源,有对抵抗的一个低基因障碍的抗病毒的药仍然广泛地在中国被使用。个性化的抗病毒的治疗仔细与翻译的药被联系,它在 genomics,有免疫力的 biomarkers,和纤维变性上从研究利用信息。这些研究的结果在进一步改进治疗结果是关键的。 | Rui Yu Rong Fan Jinlin Hou | 2014 | Frontiers of Medicine2014，8，2： | 43 |
| 3 | Comparative Study between Robotic Total Thyroidectomy with Central Lymph Node Dissection via Bilateral Axillo-breast Approach and Conventional Open Procedure for Papillary Thyroid Microcarcinoma显示文摘 | Qing-Qing He Jian Zhu Da-Yong Zhuang Zi-Yi Fan Lu-Ming Zheng Peng Zhou Lei Hou Fang Yu Yan-Ning Li Lei Xiao Xue-Feng Dong Gao-Feng Ni | 2016 | Chinese Medical Journal2016，，18： | 42 |
| 4 | Cardiomyocyte overexpression of miR-27b induces cardiac hypertrophy and dysfunction in mice显示文摘最近的研究开始在心脏的肥大和机能障碍的致病揭示了 microRNAs (miRNAs ) 的关键角色。在这研究,我们测试了是否转变生长 factor-β(TGF-β) 调整 miRNA 在心脏的肥大和心失败(HF ) 的发展起了一个枢轴的作用。我们观察到 miR-27b 是在 cardiomyocyte 特定的 Smad4 猛烈老鼠的心的 upregulated,它开发了心脏的肥大。在 vitro,实验证明 miR-27b 表示能被 TGF-β 禁止; 1 并且它的 overexpression 支持了 hypertrophic 房间生长,当 miR-27b 抑制导致了 hypertrophic 房间的抑制时,生长由 phenylephrine (PE ) 引起了处理。而且,有 miR-27b 的 cardiomyocyte 特定的 overexpression 的转基因的老鼠的分析表明 miR-27b overexpression 是足够的导致心脏的肥大和机能障碍。我们验证了 peroxisome 激活 proliferator 的 receptor-γ(PPAR-γ) 作为在 cardiomyocyte 的 miR-27b 的一个直接目标。一致地, miR-27b 转基因的老鼠显著地显示了 PPAR-γ 的底层;比控制鼠标。而且,在用在一只 pressure-overload-induced 老鼠的特定的 antagomir 的 miR-27b 的 vivo silencing, HF 的模型增加了心脏的 PPAR-γ表示,稀释心脏的肥大和机能障碍。我们的学习的结果表明那 TGF-β 1-regulated miR-27b 涉及心脏的肥大的规定,并且为心脏病作为一个有效治疗学的目标验证 miR-27b。 | Jian Wang Yao Song Yan Zhang Han Xiao Qiang Sun Ning Hou Shuilong Guo Youliang Wang Kaiji Fan Dawei Zhan Lagabaiyila Zha Yang Cao Zhenhua Li Xuan Cheng Youyi Zhang Xiao Yang | 2012 | Cell Research2012，22，3： | 36 |
| 5 | Analyzing the Flavor Compounds in Chinese Traditional Fermented Shrimp Pastes by HS-SPME-GC/MS and Electronic Nose显示文摘Shrimp paste is a type of condiments with high nutritional value.However,the flavors of shrimp paste,particularly the non-uniformity flavors,have limited its application in food processing.In order to identify the characteristic flavor compounds in Chinese traditional shrimp pastes,five kinds of typical commercial products were evaluated in this study.The differences in the volatile composition of the five products were investigated.Solid phase micro-extraction method was employed to extract the volatile compounds.GC-MS and electronic nose were applied to identify the compounds,and the data were analyzed using principal component analysis(PCA).A total of 62 volatile compounds were identified,including 8 alcohols,7 aldehydes,3 ketones,7 ethers,7 acids,3 esters,6 hydrocarbons,12 pyrazines,2 phenols,and 7 other compounds.The typical volatile compounds contributing to the flavor of shrimp paste were found as follows:dimethyl disulfide,dimethyl tetrasulfide,dimethyl trisulfide,2,3,5-trimethyl-6-ethyl pyrazine,ethyl-2,5-dimethyl-pyrazine,phenol and indole.Propanoic acid,butanoic acid,furans,and 2-hydroxy-3-pentanone caused unpleasant odors,such as pungent and rancid odors.Principal component analysis showed that the content of volatile compounds varied depending on the processing conditions and shrimp species.These results indicated that the combinations of multiple analysis and identification methods could make up the limitations of a single method,enhance the accuracy of identification,and provide useful information for sensory research and product development. | FAN Yan YIN Li-ang XUE Yong LI Zhaojie HOU Hu XUE Changhu | 2017 | Journal of Ocean University of China2017，16，2： | 25 |
| 6 | Pre-treatment with IL-1β enhances the efficacy of MSC transplantation in DSS-induced colitis显示文摘间充质的干细胞(MSC ) 试验性地被使用了对待煽动性的混乱,部分由于他们的抑制免疫力的性质。尽管 interleukin-1β(IL-1β) 是最重要的煽动性的调停人之一,成长证据显示那 IL-1β发信号得到 MSC 的抑制免疫力的性质。然而,它仍然保持不清楚怎么 IL-1β发信号完成这项活动。这里,我们集中于 IL-1β 的治疗学的功效;在葡聚糖硫酸盐钠(决策支持系统) 的告知的 MSC 劝诱了大肠炎模型,除了加重的机制。我们首先发现了那 IL-1β没有在 vitro 的任何看得见的显型变化,告知的 MSC 显著地稀释了导致决策支持系统的鼠科的大肠炎的发展。而且, IL-1β告知的 MSC 通过提高 cyclooxygenase-2 (COX-2 ) 在怒气和 mesenteric 淋巴节点(MLN ) 调制了有免疫力的房间的平衡, IL-6 和 IL-8 表示并且影响腹巨噬细胞的极化。重要地, IL-1β告知的 MSC 拥有了一个提高的能力经由 chemokine 受体类型 4 的 upregulation (CXCR4 ) 移居到内脏的煽动性的地点表示。在摘要, IL-1β告知的 MSC 在对待导致决策支持系统的大肠炎改进了功效,它部分至少取决于他们的增加的抑制免疫力的能力和提高的迁居能力。 | Hongye Fan Guangfeng Zhao Liu Liu Fei Liu Wei Gong Xianqin Liu Liu Yang Jianjun Wang Yayi Hou | 2012 | Cellular & Molecular Immunology2012，9，6： | 21 |
| 7 | Proteomic analysis of human ovaries from normal and polycystic ovarian syndrome显示文摘 | Ma,X Fan,L Meng,Y Hou,Z Mao,YDL Wang,W Ding,W Liu,JY | 2007 | 南京医科大学学报(自然科学版)2007，27，11： | 20 |
| 8 | Genome-scale profiling of circulating cell-free DNA signatures for early detection of hepatocellular carcinoma in cirrhotic patients显示文摘Dear Editor,Hepatocellular carcinoma(HCC)is the second most deadly cancer worldwide.1 Cirrhosis of different causes predisposes patients to HCC,increasing the annual HCC incidence by 2%–4%.1 The development of cirrhosis facilitates a series of genetic or epigenetic changes,resulting in the formation of dysplastic nodules,a premalignant stage in HCC.1 HCC diagnosis at an early stage contributes to an improved prognosis with the possibility of curative treatment.Due to the low accuracy of current diagnostic methods,it is urgently needed to explore new non-invasive strategies for early HCC diagnosis in cirrhotic patients. | Lei Chen Ghassan K.Abou-Alfa Bo Zheng Jing-Feng Liu Jian Bai Lu-Tao Du Yun-Song Qian Rong Fan Xiao-Long Liu Lin Wu Jin-Lin Hou Hong-Yang Wang The PreCar Team | 2021 | Cell Research2021，31，5： | 20 |
| 9 | Precise nanomedicine for intelligent therapy of cancer显示文摘Precise nanomedicine has been extensively explored for efficient cancer imaging and targeted cancer therapy, as evidenced by a few breakthroughs in their preclinical and clinical explorations. Here, we demonstrate the recent advances of intelligent cancer nanomedicine, and discuss the comprehensive understanding of their structure-function relationship for smart and efficient cancer nanomedicine including various imaging and therapeutic applications, as well as nanotoxicity. In particular, a few emerging strategies that have advanced cancer nanomedicine are also highlighted as the emerging focus such as tumor imprisonment, supramolecular chemotherapy, and DNA nanorobot. The challenge and outlook of some scientific and engineering issues are also discussed in future development. We wish to highlight these new progress of precise nanomedicine with the ultimate goal to inspire more successful explorations of intelligent nanoparticles for future clinical translations. | Huabing Chen Zhanjun Gu Hongwei An Chunying Chen Jie Chen Ran Cui Siqin Chen Weihai Chen Xuesi Chen Xiaoyuan Chen Zhuo Chen Baoquan Ding Qian Dong Qin Fan Ting Fu Dayong Hou Qiao Jiang Hengte Ke Xiqun Jiang Gang Liu Suping Li Tianyu Li Zhuang Liu Guangjun Nie Muhammad Ovais Daiwen Pang Nasha Qiu Youqing Shen Huayu Tian Chao Wang Hao Wang Ziqi Wang Huaping Xu Jiang-Fei Xu Xiangliang Yang Shuang Zhu Xianchuang Zheng Xianzheng Zhang Yanbing Zhao Weihong Tan Xi Zhang Yuliang Zhao | 2018 | Science China Chemistry2018，61，12： | 19 |
| 10 | B, ntiviral and anti-inflammatory activity of arbidol hydrochloride in influenza A (HIN1) virus infection显示文摘 | Qiang LIU Hai-rong XIONG Li LU Yuan-yuan LIU Fan LUO Wei HOU Zhan-qiu YANG | 2013 | Acta Pharmacologica Sinica2013，34，8： | 18 |
| 11 | Evaluation of Antibody-Dependent Enhancement of SARS-CoV Infection in Rhesus Macaques Immunized with an Inactivated SARS-CoV Vaccine显示文摘Dear Editor,In 2003,severe acute respiratory syndrome coronavirus(SARS-CoV)emerged in Guangdong Province,China,infected more than 8000 individuals,and resulted in a 10%mortality rate(Rota et al.2003).Later,in 2012,a novel CoV,Middle East respiratory syndrome coronavirus(MERS-CoV),was isolated from the sputum of a man in Saudi Arabia(Perl et al.2014).Notably。 | Fan Luo Fan-Lu Liao Hui Wang Hong-Bin Tang Zhan-Qiu Yang Wei Hou | 2018 | Virologica Sinica2018，33，2： | 17 |
| 12 | Efficacy and safety of Shexiang Baoxin pill(MUSKARDIA)in patients with stable coronary artery disease:a multicenter,double-blind,placebo-controlled phase IV randomized clinical trial显示文摘Background:The Shexiang Baoxin Pill(MUSKARDIA)has been used for treating coronary artery disease(CAD)and angina for more than 30 years in China.Nevertheless,methodologically sound trials on the use of MUSKARDIA in CAD patients are scarce.The aim of the study is to determine the effects of MUSKARDIA as an add-on to optimal medical therapy(OMT)in patients with stable CAD.Methods:A total of 2674 participants with stable CAD from 97 hospitals in China were randomized 1:1 to a MUSKARDIA or placebo group for 24 months.Both groups received OMT according to local tertiary hospital protocols.The primary outcome was the occurrence of a major adverse cardiovascular event(MACE),defined as a composite of cardiovascular death,non-fatal myocardial infarction(MI),or non-fatal stroke.Secondary outcomes included all-cause mortality,non-fatal MI,non-fatal stroke,hospitalization for unstable angina or heart failure,peripheral revascularization,angina stability and angina frequency.Results:In all,99.7%of the patients were treated with aspirin and 93.0%with statin.After 2 years of treatment,the occurrence of MACEs was reduced by 26.9%in the MUSKARDIA group(MUSKARDIA:1.9%vs.placebo:2.6%;odds ratio=0.80;95%confidence interval:0.45-1.07;P=0.2869).Angina frequency was significantly reduced in the MUSKARDIA group at 18 months(P=0.0362).Other secondary endpoints were similar between the two groups.The rates of adverse events were also similar between the two groups(MUSKARDIA:17.7%vs.placebo:17.4%,P=0.8785).Conclusions:As an add-on to OMT,MUSKARDIA is safe and significantly reduces angina frequency in patients with stable CAD.Moreover,the use of MUSKARDIA is associated with a trend toward reduced MACEs in patients with stable CAD.The results suggest that MUSKARDIA can be used to manage patients with CAD.Trial registration:chictr.org.cn,No.ChiCTR-TRC-12003513. | Jun-Bo Ge Wei-Hu Fan Jing-Min Zhou Hai-Ming Shi Fu-Sui Ji Yang Wu Yu-Lan Zhao Jun Qian Yuan-Zhe Jin Ying-Wu Liu Sheng-Huang Wang Sheng-Hu He Ping Yang Jie Wu Feng Lu Zi-Shan Hou | 2021 | Chinese Medical Journal2021，，2： | 17 |
| 13 | A study of internal solitary waves observed on the continental shelf in the northwestern South China Sea显示文摘Based on in-situ time series data from the acoustic Doppler current profiler (ADCP) and thermistor chain in Wenchang area, a sequence of internal solitary wave (ISW) packets was observed in September 2005, propagating northwest on the continental shelf of the northwestern South China Sea (SCS). Corresponding to different stratification of the water column and tidal condition, both elevation and depression ISWs were observed at the same mooring location with amplitude of 35 m and 25 m respectively in different days. Regular arrival of the remarkable ISW packets at approximately the diurnal tidal period and the dominance of diurnal internal waves in the study area, strongly suggest that the main energy source of the waves is the diurnal tide. Notice that the wave packets were all riding on the troughs and shoulders of the internal tides, they were probably generated locally from the shelf break by the evolution of the internal tides due to nonlinear and dispersive effects. | XU Zhenhua YIN Baoshu HOU Yijun FAN Zhisong Antony K LIU | 2010 | Acta Oceanologica Sinica2010，29，3： | 17 |
| 14 | Discovery of biclonal origin and a novel oncogene SLC12A5 in colon cancer by single-cell sequencing显示文摘单个房间的定序是为描出的一个强大的工具为个性化的癌症管理的同种细胞的关系和识别关键司机基因。这里,我们执行了结肠癌的一个盒子的单个房间的定序的分析。人口遗传分析在肿瘤房间人口识别了二独立克隆。主要肿瘤克隆作为早 oncogenic 事件怀有 APC 和 TP53 变化,而次要的克隆包含了优势的 CDC27 和 PABPC1 变化。在这二克隆的次要的克隆支持的 APC 和 TP53 变化的缺席从二细胞的起源被导出。体的变化等位基因频率系列的检查另外 21 个整个织物的定序 exome 的盒子在结肠癌揭示了同种细胞的起源的异质。下次,我们识别了在单个房间的水平显示出变化的高频率,但是在人口水平展出了低流行的变异的基因 SLC12A5。变异的 SLC12A5 的功能的描述在结肠癌揭示了它的潜在的 oncogenic 效果。我们的学习在单个房间的水平支持提供第一条 exome 宽的证据那结肠癌能具有 biclonal 起源,并且建议在一个队的低流行的变化可以也在单个水平起重要 protumorigenic 作用。 | Chang Yu Jun Yu Xlaotlan Yao Wllham KK Wu Youyong Lu Senwel Tang Xiangchun Li Li Bao Xiaoxing Li Yong Hou Renhua Wu Min Jian Ruoyan Chen Fan Zhang Lixia Xu Fan Fan Jun He Qiaoyi Liang Hongyi Wang Xueda Hu Minghui He Xiang Zhang Hancheng Zheng Qibin Li Hanjie Wu Yan Chen Xu Yang Shida Zhu Xun Xu Huanming Yang Jian Wang Xiuqing Zhang Joseph JY Sung Yingrui Li Jun Wang | 2014 | Cell Research2014，，6： | 16 |
| 15 | Western medication plus Traditional Chinese Medicine preparations in patients with chronic heart failure:a prospective,single-blind,randomized,controlled,and multicenter clinical trial显示文摘OBJECTIVE: To assess the efficacy and safety in patients with chronic heart failure(CHF) of Western medication plus Traditional Chinese Medicine(TCM) preparations.METHODS: This prospective, single-blind, randomized, controlled, and multicenter clinical trial began on September 17, 2008, and was completed on June 25, 2011. A total of 340 inpatients, aged 40-79 years, with exacerbating CHF from 10 hospitals were enrolled and randomly allocated within 24 h of admission. The trial included three intervention periods. During hospitalization, the control group received western medication for CHF and the treatment group received Danhong injection with Shenfu injection or Shenmai injection. After discharge,all patients were treated with Qiliqiangxin capsules and Buyiqiangxin tablets or a placebo for 6 months. After the 6-month intervention, both groups received only continuous western medication. The primary endpoint was all-cause mortality.The efficacy assessments were as follows: B-type natriuretic peptide(BNP), Lee's HF score, the 6-minute walking test(6 MWT), left ventricular ejection fraction(LVEF), and the Minnesota Living with Heart Failure Questionnaire(MLHFQ). The safety assessments were as follows: blood and urine routine examination, hepatic and renal function, electrolytes in blood and adverse events.RESULTS: Compared with the control group, the treatment group showed a 30.99% reduction in all-cause mortality and an improved survival rate.The treatment group showed greater improvement in 6 MWT(P = 0.02) than the control group on discharge, after 12-month follow-up, there was a time-group interaction for MLHFQ(P = 0.03). Incidence rate of adverse events and other relevant safety indexes were not statistically significant between the two groups.CONCLUSION: Western medication plus TCM treatment can increase 6-minute walking distance(improve exercise tolerance) and quality of life with heart failure patients. | Wang Xianliang Hou Yazhu Mao Jingyuan Zhao Yingqiang Niu Tianfu Yuan Ruyu Wang Yonggang Cui Jin-rong Shi Le Jia Xiuli Fan Ruihong Lin Qian Zhang Yan Li Zhijun Shang Hongcai Wang Baohe Wang Hongwu Wang Henghe Cui Xiaolei Soh Shanbin Ruan Jishou Zhang Boli | 2017 | Journal of Traditional Chinese Medicine2017，37，6： | 15 |
| 16 | Biofunctional magnesium coated Ti6Al4V scaffold enhances osteogenesis and angiogenesis in vitro and in vivo for orthopedic application显示文摘The insufficient osteogenesis and osseointegration of porous titanium based scaffold limit its further application.Early angiogenesis is important for scaffold survival.It is necessary to develop a multifunctional surface on titanium scaffold with both osteogenic and angiogenic properties.In this study,a biofunctional magnesium coating is deposited on porous Ti6Al4V scaffold.For osseointegration and osteogenesis analysis,in vitro studies reveal that magnesium-coated Ti6Al4V co-culture with MC3T3-E1 cells can improve cell proliferation,adhesion,extracellular matrix(ECM)mineralization and ALP activity compared with bare Ti6Al4V cocultivation.Additionally,MC3T3-E1 cells cultured with magnesium-coated Ti6Al4V show significantly higher osteogenesisrelated genes expression.In vivo studies including fluorochrome labeling,micro-computerized tomography and histological examination of magnesium-coated Ti6Al4V scaffold reveal that new bone regeneration is significantly increased in rabbits after implantation.For angiogenesis studies,magnesium-coated Ti6Al4V improve HUVECs proliferation,adhesion,tube formation,wound-healing and Transwell abilities.HUVECs cultured with magnesium-coated Ti6Al4V display significantly higher angiogenesis-related genes(HIF-1αand VEGF)expression.Microangiography analysis reveal that magnesium-coated Ti6Al4V scaffold can significantly enhance the blood vessel formation.This study enlarges the application scope of magnesium and provides an optional choice to the conventional porous Ti6Al4V scaffold with enhanced osteogenesis and angiogenesis for further orthopedic applications. | Peng Gao Bo Fan Xiaoming Yu Wenwen Liu Jie Wu Lei Shi Di Yang Lili Tan Peng Wan Yulin Hao Shujun Li Wentao Hou Ke Yang Xiaokang Li Zheng Guo | 2020 | Bioactive Materials2020，5，3： | 15 |
| 17 | Magnolol additive as a replacer of antibiotic enhances the growth performance of Linwu ducks显示文摘Magnolol rich in Magnolia officinalis is a bioactive polyphenolic compound. The aim of this study was to examine the effects of magnolol additive(MA) on growth performance, expression levels of antioxidantrelated genes, and intestinal mucosal morphology of Linwu ducks aged from 49 to 70 days, comparing with that of an antibiotic additive(colistin sulfate [CS]). A total of 275,49-day-old ducks were assigned to5 groups with 5 cages of 11 ducks each and fed diets supplemented with 0,100, 200 and 300 mg of MA/kg and 300 mg of CS/kg for 3 weeks, respectively. The results showed that the average daily body weight gain(ADG) was increased significantly in MA-fed groups(200 and 300 mg/kg), compared with the basal diet(BD) group(P < 0.05). The mRNA levels of superoxide dismutase-1(SOD1), manganese superoxide dismutase-2(MnSOD2) and catalase(CAT) were also increased significantly in MA groups(P < 0.05). In addition, hematoxylin and eosin staining revealed that Linwu ducks fed the diets with MA had more intact intestinal mucosa than those fed the BD and CS diets. In addition, ileal villus height, ileal villus height/crypt depth ratio(V/C) and duodenal V/C were also improved significantly(P < 0.05). Taken together, these data demonstrated that MA is an effective feed additive to enhance the growth performance of the Linwu ducks by improving the antioxidant and intestinal mucosal status, suggesting that MA will be a potential additive to replace antibiotic(CS). | Qian Lin Jianfei Zhao Kun Xie Yushi Wang Guili Hu Guitao Jiang Qiuzhong Dai Zhiyong Fan Jianhua He Xi He De-Xing Hou | 2017 | Animal Nutrition2017，，2： | 14 |
| 18 | The Deep-Time Digital Earth program:data-driven discovery in geosciences显示文摘Current barriers hindering data-driven discoveries in deep-time Earth(DE)include:substantial volumes of DE data are not digitized;many DE databases do not adhere to FAIR(findable,accessible,interoperable and reusable)principles;we lack a systematic knowledge graph for DE;existing DE databases are geographically heterogeneous;a significant fraction of DE data is not in open-access formats;tailored tools are needed.These challenges motivate the Deep-Time Digital Earth(DDE)program initiated by the International Union of Geological Sciences and developed in cooperation with national geological surveys,professional associations,academic institutions and scientists around the world.DDE’s mission is to build on previous research to develop a systematic DE knowledge graph,a FAIR data infrastructure that links existing databases and makes dark data visible,and tailored tools for DE data,which are universally accessible.DDE aims to harmonize DE data,share global geoscience knowledge and facilitate data-driven discovery in the understanding of Earth’s evolution. | Chengshan Wang Robert MHazen Qiuming Cheng Michael HStephenson Chenghu Zhou Peter Fox Shu-zhong Shen Roland Oberhansli Zengqian Hou Xiaogang Ma Zhiqiang Feng Junxuan Fan Chao Ma Xiumian Hu Bin Luo Juanle Wang Craig M.Schiffries | 2021 | National Science Review2021，8，9： | 14 |
| 19 | Comparison of coalbed gas generation between Huaibei-Huainan coalfields and Qinshui coal basin based on the tectono-thermal modeling显示文摘The geothermal history and the tectonic subsidence history of the Huaibei-Huainan coalfields were reconstructed by using the vitrinite reflectance data, and their correlative restriction on coalbed gas generation of Huaibei-Huainan coalfields and Qinshui coal basin was discussed. The burial, thermal, and maturity histories of are similar between Huaibei coalfield and Huainan coalfield, obviously different from those of Qinshui coal basin. Based on the tectono-thermal evolution characters of Huaibei-Huainan coalfields and Qinshui basin, the process of coalbed gas generation can be divided into three stages: (1) During Early Mesozoic, both in Huaibei-Huainan and Qinshui, the buried depth of Permian coal seams increased rapidly, which resulted in strong metamorphism and high burial temperature of coal seams. At this stage, the coal rank was mainly fat coal, and locally reached coking coal. These created an environment favoring the generation of thermogenic gas. (2) From Late Jurassic to Cretaceous, in the areas of Huaibei-Huainan, the strata suffered from erosion and the crust became thinning, and the Permian coal-bearing strata were uplifted to surface. At this stage, the thermogenic gas mostly escaped. Conversely, in Qinshui basin, the cover strata of coal seams kept intact during this stage, and the thermogenic gas were mostly preserved. Furthermore, with the interaction of magmatism, the burial temperature of coal seams reached higher peak value, and it was suitable for the secondary generation of thermogenic gas. (3) From Paleogene onward, in area of Huainan-Huaibei, the maturity of coal and burial temperature were propitious to the generation of secondary biogenic gases. However, in Qinshui basin, the maturity of coal went against genesis of second biogenic gas or thermogenic gas. By comparison, Huaibei-Huainan coalfields are dominated by thermogenic gas with a significant biogenic gas and hydrodynamic overprint, whereas Qinshui basin is dominated mainly by thermogenic gas. | WU YuDong JU YiWen HOU QuanLin HU ShengBiao PAN JieNan FAN JunJia | 2011 | Science China Earth Sciences2011，54，7： | 13 |
| 20 | Toward a stepwise Kwangsian Orogeny显示文摘The Kwangsian Orogeny originated along the southeast coast of China and stepwise developed in a northwest direction.It includes two stages,a long locally varying uplift from the Late Ordovician to the early Silurian and a finally tectonic movement near the Silurian and Devonian transition.The Kwangsian uplift event shows a stepwise delay northwestwards from the southeastern coast area in Nemagraptus gracilis Biozone(Sa1)to the south side of the Xuefeng Mountains in or later than Cystograptus vesiculosus Biozone(R3)to Coronograptus cyphus Biozone(R4).In the southern of Yangtze Platform,the Yichang Uplift was droved by the Kwangsian Orogeny forming a diachronous stratigraphical break through Rhuddanian and Aeronian.The distribution of the early Telychian lower marine red beds indicates a northwestward increase of the Cathaysian Oldland.Stratigraphical evidence may explain why the Kwangsian movement was marked by an angular disconformity during the Pridoli to earliest Devonian interval. | CHEN Xu FAN JunXuan CHEN Qing TANG Lan HOU XuDong | 2014 | Science China Earth Sciences2014，57，3： | 13 |
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