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| 1 | Effects of process parameters on pore structure of semi-coke prepared by solid heat carrier with dry distillation显示文摘The semi-coke was prepared by solid heat carrier with dry distillation in single factor method. The pore structures of raw coal and semi-coke were characterized by Brunauer-Emmett-Teller (BET) and scanning electron microscope (SEM). The results show that the adsorption and desorption isotherm of semi-coke are not coincident. There was a wide pore distribution on the semi-coke, in which mesopores and micropores account for a considerable proportion. Also there are many more secondary pores. With the increase of the final temperature of heat carrier and constant temperature, as well as the decrease of volume ratio of coal and hot carrier reactor, specific surface area and pore volume of semi-coke increased rapidly first and then decreased and finally increased, along with the rapidly reduction of average pore size. SEM photos show that the surface of semi-coke becomes increasingly rough and glossy. | Zhou, Guoli Wu, Jianjun Miao, Zhenyong Hu, Xuelian Li, Xia Shi, Xin Cai, Zhidan Shang, Yukun | 2013 | International Journal of Mining Science and Technology2013，23，3： | 20 |
| 2 | Postoperative chemotherapy with S-1 plus oxaliplatin versus S-1alone in locally advanced gastric cancer(RESCUE-GC study): a protocol for a phase Ⅲ randomized controlled trial显示文摘Background:The ACTS-GC study had shown postoperative adjuvant therapy with S-1 improved survival of patients with locally advanced gastric cancer.Addition of oxaliplatin to S-1 is considered to be acceptable as one of the treatment options for gastric cancer patients after radical gastrectomy with D2 lymph node excision.Methods:We have commenced a randomized phase III trial in December 2016 to evaluate S-1 plus oxaliplatin compared with S-1 alone in the adjuvant setting for locally advanced gastric cancer.A total of 564 patients will be accrued from 13 Chinese institutions in two years.The primary endpoint is 3-year relapse-free survival.The secondary endpoints are 5-year overall survival,proportion of patients who complete the postoperative chemotherapy and incidence of adverse events.Ethic and dissemination:The trial has been approved by the institutional review board of each participating institution and it was activated on December,2016.The enrollment will be finished in December,2018.Patient’s follow-up will be ended until December,2023.Trial registration:Clinical Trials.gov,identifier:NCT02867839.Registered on August 4,2016. | Xiang Hu Lin Chen Yian Du Biao Fan Zhaode Bu Xin Wang Yingjiang Ye Zhongtao Zhang Gang Xiao Fei Li Qingsi He Guoli Li Xian Shen Bin Xiong Liming Zhu Jiwei Liui Lian Liu Tao Wu Jing Zhou Jun Zhang Gang Zhao Xulin Wang Pin Liang Xinxin Wang Yan Zhang Xiaojiang Wu Ji Zhang Xin Ji Xianglong Zong Tao Fu Ziyu Jia Jiafu Ji | 2017 | Chinese Journal of Cancer Research2017，29，2： | 5 |
| 3 | PIP5k1β controls bone homeostasis through modulating both osteoclast and osteoblast differentiation显示文摘PIP5k1βis crucial to the generation of phosphotidylinosotol(4,5)P2.PIP5k1βparticipates in numerous cellular activities,such as B cell and platelet activation,cell phagocytosis and endocytosis,cell apoptosis,and cytoskeletal organization.In the present work,we aimed to examine the function of PIP5k1βin osteoclastogenesis and osteogenesis to provide promising strategies for osteoporosis prevention and treatment.We discovered that PIP5k1β deletion in mice resulted in obvious bone loss and that PIP5k1β was highly expressed during both osteoclast and osteoblast differentiation.Deletion of the gene was found to enhance the proliferation and migration of bone marrow-derived macrophage-like cells to promote osteoclast differentiation.PIP5k1β-/-osteoclasts exhibited normal cytoskeleton architecture but stronger resorption activity.PIP5kip deficiency also promoted activation of mitogen-activated kinase and Akt signaling,enhanced TRAF6 and c-Fos expression,facilitated the expression and nuclear translocation of NFATC1,and upregulated Grb2 expression,thereby accelerating osteoclast differentiation and function.Finally,PIP5k1β enhanced osteoblast differentiation by upregulating master gene expression through triggering smad1/5/8 signaling.Therefore,PIP5k1βmodulates bone homeostasis and remodeling. | Xiaoying Zhao Penglei Cui Guoli Hu Chuandong Wang Lei Jiang Jingyu Zhao Jiake Xu Xiaoling Zhang | 2020 | Journal of Molecular Cell Biology2020，12，1： | 4 |
| 4 | Extraction,Isolation and Structural Characterization of Polysaccharides from a Red Alga Gloiopeltis furcata显示文摘Three kinds of polysaccharides:GFW,GFH and GFA,were sequentially extracted from a red alga Gloiopeltis furcatawith 25℃and 85℃water,and 60℃ 4%NaOHwater solution.Based on the defatted alga,the yields of the polysaccharide were57.9%,2.5%and 2.6%,respectively.Their monosaccharide compositions,average molecular weights and structural characters weredetermined by gas chromatography(GC),high performance liquid chromatography(HPLC),fourier transform infrared spectroscopy(FTIR)or13C-NMR spectroscopy.The results showed that GFW,GFH and GFA were all composed of D-galactose(Gal)and3,6-anhydro-L-galactose(AnG),and particularly GFA also contained xylose(Xyl).The average molecular weights of GFW,GFHand GFA were 22.6 kD,26.5 kD and 49.8 kD,respectively,with the respective sulfate content 31.2%,25.1%and 22.7%.The data ofFTIR and13C-NMR confirmed the sulfate ester location at C6 of galactose.It is concluded that all the three polysaccharides extractedfrom Gloiopeltis furcata were sulfated galactans,two being sulfated-agarose,and one being xylose-containing sulfated galactan. | YU Guangli HU Yannan YANG Bo ZHAO Xia WANG Peipei JI Guoli WU Jiandong GUAN Huashi | 2010 | Journal of Ocean University of China2010，9，2： | 3 |
| 5 | The cellular niche for intestinal stem cells: ateam effort显示文摘The rapidly self-renewing epithelium in the mammalian intestine is maintained by multipotent intestinal stem cells(ISCs) located at the bottom of the intestinal crypt that are interspersed with Paneth cells in the small intestine andPaneth-like cells in the colon. The ISC compartment is also closely associated with a sub-epithelial compartmentthat contains multiple types of mesenchymal stromal cells. With the advances in single cell and gene editingtechnologies, rapid progress has been made for the identification and characterization of the cellular componentsof the niche microenvironment that is essential for self-renewal and differentiation of ISCs. It has becomeincreasingly clear that a heterogeneous population of mesenchymal cells as well as the Paneth cells collectivelyprovide multiple secreted niche signals to promote ISC self-renewal. Here we review and summarize recentadvances in the regulation of ISCs with a main focus on the definition of niche cells that sustain ISCs. | Guoli Zhu Jiulong Hu Rongwen Xi | 2021 | Cell Regeneration2021，10，1： | 3 |
| 6 | Early Mesozoic structural deformation in the Chuandian N-S Tectonic Belt,China显示文摘The Helan-Chuandian N-S Tectonic Belt is a mantle transitional belt in China.The southern part,forming the Chuandian N-S Tectonic Belt,comprises several tectonic systems,each displaying different characteristics.The Chuandian N-S Tectonic Belt along the western margin of Yangtze Block is a strike-slip tectonic belt with a series of echelon left-lateral slip faults.The strike-slip fault systems experienced two stages of structural deformation:early NW-SE striking thrust faults formed under a NE-SW compression stress field,and later sinistral strike-slip structures formed along thrust faults under a NW-SE compression stress field.Mesozoic basins developed between the left-lateral slip faults.Sedimentary facies and paleocurrent directions indicate that basin development was controlled by the strike-slip faults.The oldest strata in the Chuandian N-S Tectonic Belt constrain its formation to early Mesozoic.In fact,The slip tectonic belt formed by clockwise rotation and north-directed subduction-collision of the Yangtze Block in Late Triassic-Jurassic.The strike-slip faults that developed within the belt also formed at this time. | CHEN Hong HU JianMin QU HongJie WU GuoLi | 2011 | Science China Earth Sciences2011，54，11： | 2 |
| 7 | Progress in octahedral spherical hohlraum study显示文摘In this paper,we give a review of our theoretical and experimental progress in octahedral spherical hohlraum study.From our theoretical study,the octahedral spherical hohlraums with 6 Laser Entrance Holes(LEHs)of octahedral symmetry have robust high symmetry during the capsule implosion at hohlraum-to-capsule radius ratio larger than 3.7.In addition,the octahedral spherical hohlraums also have potential superiority on low backscattering without supplementary technology.We studied the laser arrangement and constraints of the octahedral spherical hohlraums,and gave a design on the laser arrangement for ignition octahedral hohlraums.As a result,the injection angle of laser beams of 50°-60°was proposed as the optimum candidate range for the octahedral spherical hohlraums.We proposed a novel octahedral spherical hohlraum with cylindrical LEHs and LEH shields,in order to increase the laser coupling efficiency and improve the capsule symmetry and to mitigate the influence of the wall blowoff on laser transport.We studied on the sensitivity of the octahedral spherical hohlraums to random errors and compared the sensitivity among the octahedral spherical hohlraums,the rugby hohlraums and the cylindrical hohlraums,and the results show that the octahedral spherical hohlraums are robust to these random errors while the cylindrical hohlraums are the most sensitive.Up till to now,we have carried out three experiments on the spherical hohlraum with 2 LEHs on Shenguang(SG)laser facilities,including demonstration of improving laser transport by using the cylindrical LEHs in the spherical hohlraums,spherical hohlraum energetics on the SGIII prototype laser facility,and comparisons of laser plasma instabilities between the spherical hohlraums and the cylindrical hohlraums on the SGIII laser facility. | Ke Lan Jie Liu Zhichao Li Xufei Xie Wenyi Huo Yaohua Chen Guoli Ren Chunyang Zheng Dong Yang Sanwei Li Zhiwen Yang Liang Guo Shu Li Mingyu Zhang Xiaoying Han Chuanlei Zhai Lifei Hou Yukun Li Keli Deng Zheng Yuan Xiayu Zhan Feng Wang Guanghui Yuan Haijun Zhang Bobin Jiang Lizhen Huang Wei Zhang Kai Du Runchang Zhao Ping Li Wei Wang Jingqin Su Xuewei Deng Dongxia Hu Wei Zhou Huaiting Jia Yongkun Ding Wanguo Zheng Xiantu He | 2016 | Matter and Radiation at Extremes2016，1，1： | 2 |
| 8 | Aluminum-doped zirconia-sup-ported copper nanocatalysts: surface synergistic catalytic effects inthe gas-phase hydrogenation of esters显示文摘 | Hu Qi Fan Guoli Yang Lan | 2014 | Chem Cat Chem2014，6，： | 1 |
| 9 | Technologies and practice of CO2 flooding and sequestration in China显示文摘The latest advancement of CO2 flooding and sequestration theory and technology in China is systematically described, and the future development direction is put forward. Based on the geological characteristics of continental reservoirs, five theories and key technologies have been developed:(1) Enriched the understandings about the mass transfer characteristics of components between CO2 and crude oil in continental reservoirs, micro-flooding mechanism and sequestration mechanism of different geological bodies.(2) Established the design method of reservoir engineering parameters, injection-production control technology and development effect evaluation technology of CO2 flooding, etc.(3) Developed a series of production engineering technologies such as separated layer CO2 injection technology, high efficiency lifting technology, on-line wellbore corrosion monitoring and protection technology.(4) Innovated a series of surface engineering technology including CO2 capture technology, pipeline CO2 transportation, CO2 surface injection, and production gas circulation injection, etc.(5) Formed a series of supporting technologies including monitoring, and safety and environmental protection evaluation of CO2 flooding reservoir. On this basis, the technological development directions in the future have been put forward:(1) Breakthrough in low-cost CO2 capture technology to provide cheap CO2 gas source;(2) Improve the miscibility technology between CO2 and crude oil to enhance oil displacement efficiency;(3) Improve CO2 sweeping volume;(4) Develop more effective lifting tools and technologies;(5) Strengthen the research of basic theory and key technology of CO2 storage monitoring. CO2 flooding and sequestration in the Jilin Oilfield shows that this technology has broad application prospects in China. | HU Yongle HAO Mingqiang CHEN Guoli SUN Ruiyan LI Shi | 2019 | Petroleum Exploration and Development2019，46，4： | 1 |
| 10 | The Risk Factors and Environm ental Risk Prediction during the Production of Yellow Phosphorus显示文摘Phosphorus is an important chemical raw material of economy. There are several risk factors in the entire production process of yellow phosphorus. The health of the production staff was greatly endangered by the toxic and harmful substances. The generation of risk factors was analyzed during the yellow phosphorus production and its harm was discussed,and several toxic and harmful substances were tested for a number of phosphorus manufacturing enterprises. The environmental risks of P2O5 in phosphorus pollution sources were scientifically predicted on the first time. | Gao Ye Dong Guoli Zhang Jie Gao Huaping Hu Xuewei Shi Jianwu | 2014 | Meteorological and Environmental Research2014，5，10： | 1 |
| 11 | Effects of Macroparticle Sizes on Two-phase Mixture Discharge Under DC Voltage显示文摘随着放电等离子体在各个领域应用的不断扩大,两相体放电问题越来越重要,需要解决的基础问题之一即是两相体中放电发生、发展的特点和规律及影响因素。采用21种不同的介质材料研究直流电压下两相体放电的效应,由实验结果可知介质的介电常数对放电路径基本无影响,而介质颗粒的粒径大小对两相体放电路径的选择起决定作用,即粒径效应。此外,对颗粒介电常数、电场畸变、光电离作用和颗粒荷电等几个方面进行研究,可知两相体放电的粒径效应与颗粒粒径大小紧密相关。 | YAO Wenjun HE Zhenghao DENG Heming WANG Guoli ZHANG Man MA Jun LI Jin YE Qizheng HU Hui | 2012 | 中国电机工程学报2012，32，13： | 1 |
| 12 | Recent research progress of master mold manufacturing by nanoimprint technique for the novel microoptics devices显示文摘The consumer demand for emerging technologies such as augmented reality(AR),autopilot,and three-dimensional(3D)internet has rapidly promoted the application of novel optical display devices in innovative industries.However,the micro/nanomanufacturing of high-resolution optical display devices is the primary issue restricting their development.The manufacturing technology of micro/nanostructures,methods of display mechanisms,display materials,and mass production of display devices are major technical obstacles.To comprehensively understand the latest state-of-the-art and trigger new technological breakthroughs,this study reviews the recent research progress of master molds produced using nanoimprint technology for new optical devices,particularly AR glasses,new-generation light-emitting diode car lighting,and naked-eye 3D display mechanisms,and their manufacturing techniques of master molds.The focus is on the relationships among the manufacturing process,microstructure,and display of a new optical device.Nanoimprint master molds are reviewed for the manufacturing and application of new optical devices,and the challenges and prospects of the new optical device diffraction grating nanoimprint technology are discussed. | Yuhang LIU Jianjun LIN Zuohuan HU Guoli GAO Bingyang WANG Liuyi WANG Zhiyuan PAN Jianfei JIA Qinwei YIN Dengji GUO Xujin WANG | 2022 | Frontiers of Materials Science2022，16，3： | 0 |
| 13 | Overexpression of mechanical sensitive miR-337-3p alleviates ectopic ossification in rat tendinopathy model via targeting IRS1 and Nox4 of tendon-derived stem cells显示文摘Tendinopathy,which is characterized by the ectopic ossification of tendon,is a common disease occurring in certain population,such as athletes that suffer from repetitive tendon strains.However,the molecular mechanism underlying the pathogenesis of tendinopathy caused by the overuse of tendon is still lacking.Here,we found that the mechanosensitive miRNA,miR-337-3p,had lower expression under uniaxial cyclical mechanical loading in tendon-derived stem cells(TDSCs)and negatively controlled chondro-osteogenic differentiation of TDSCs.Importantly,downregulation of miR-337-3p expression was also observed in both rat and human calcified tendons,and overexpressing miR-337-3p in patellar tendons of rat tendinopathy model displayed a robust therapeutic efficiency.Mechanistically,we found that the proinflammatory cytokine interleukin-1^was the upstream factor of miR-337-3p that bridges the mechanical loading with its downregulation.Furthermore,the target genes of miR-337-3p,NADPH oxidase 4,and insulin receptor substrate 1,activated chondro-osteogenic differentiation of TDSCs through JNK and ERK signaling,respectively.Thus,these findings not only provide novel insight into the molecular mechanisms underlying ectopic ossification in tendinopathy but also highlight the significance of miR-337-3p as a putative therapeutic target for clinic treatment of tendinopathy. | Yiyun Geng Xiaoying Zhao Jiajia Xu Xudong Zhang Guoli Hu Sai-Chuen Fu Kerong Dai Xiaodong Chen Yung shu-huang Patrick Xiaoling Zhang | 2020 | Journal of Molecular Cell Biology2020，12，4： | 0 |
| 14 | Feasibility and physics potential of detecting ^(8)B solar neutrinos at JUNO显示文摘The Jiangmen Underground Neutrino Observatory(JUNO)features a 20 kt multi-purpose underground liquid scintillator sphere as its main detector.Some of JUNO's features make it an excellent location for^8B solar neutrino measurements,such as its low-energy threshold,high energy resolution compared with water Cherenkov detectors,and much larger target mass compared with previous liquid scintillator detectors.In this paper,we present a comprehensive assessment of JUNO's potential for detecting^8B solar neutrinos via the neutrino-electron elastic scattering process.A reduced 2 MeV threshold for the recoil electron energy is found to be achievable,assuming that the intrinsic radioactive background^(238)U and^(232)Th in the liquid scintillator can be controlled to 10^(-17)g/g.With ten years of data acquisition,approximately 60,000 signal and 30,000 background events are expected.This large sample will enable an examination of the distortion of the recoil electron spectrum that is dominated by the neutrino flavor transformation in the dense solar matter,which will shed new light on the inconsistency between the measured electron spectra and the predictions of the standard three-flavor neutrino oscillation framework.IfDelta m^(2)_(21)=4.8times10^(-5);(7.5times10^(-5))eV^(2),JUNO can provide evidence of neutrino oscillation in the Earth at approximately the 3sigma(2sigma)level by measuring the non-zero signal rate variation with respect to the solar zenith angle.Moreover,JUNO can simultaneously measureDelta m^2_(21)using^8B solar neutrinos to a precision of 20% or better,depending on the central value,and to sub-percent precision using reactor antineutrinos.A comparison of these two measurements from the same detector will help understand the current mild inconsistency between the value of Delta m^2_(21)reported by solar neutrino experiments and the KamLAND experiment. | Angel Abusleme Thomas Adam Shakeel Ahmad Sebastiano Aiello Muhammad Akram Nawab Ali Fengpeng An Guangpeng An Qi An Giuseppe Andronico Nikolay Anfimov Vito Antonelli Tatiana Antoshkina Burin Asavapibhop João Pedro Athayde Marcondes de André Didier Auguste Andrej Babic Wander Baldini Andrea Barresi Eric Baussan Marco Bellato Antonio Bergnoli Enrico Bernieri David Biare Thilo Birkenfeld Sylvie Blin David Blum Simon Blyth Anastasia Bolshakova Mathieu Bongrand Clément Bordereau Dominique Breton Augusto Brigatti Riccardo Brugnera Riccardo Bruno Antonio Budano Max Buesken Mario Buscemi Jose Busto Ilya Butorov Anatael Cabrera Hao Cai Xiao Cai Yanke Cai Zhiyan Cai Antonio Cammi Agustin Campeny Chuanya Cao Guofu Cao Jun Cao Rossella Caruso Cédric Cerna Jinfan Chang Yun Chang Pingping Chen Po-An Chen Shaomin Chen Shenjian Chen Xurong Chen Yi-Wen Chen Yixue Chen Yu Chen Zhang Chen Jie Cheng Yaping Cheng Alexander Chepurnov Davide Chiesa Pietro Chimenti Artem Chukanov Anna Chuvashova Gérard Claverie Catia Clementi Barbara Clerbaux Selma Conforti Di Lorenzo Daniele Corti Salvatore Costa Flavio Dal Corso Christophe De La Taille Jiawei Deng Zhi Deng Ziyan Deng Wilfried Depnering Marco Diaz Xuefeng Ding Yayun Ding Bayu Dirgantara Sergey Dmitrievsky Tadeas Dohnal Georgy Donchenko Jianmeng Dong Damien Dornic Evgeny Doroshkevich Marcos Dracos Frédéric Druillole Shuxian Du Stefano Dusini Martin Dvorak Timo Enqvist Heike Enzmann Andrea Fabbri Lukas Fajt Donghua Fan Lei Fan Can Fang Jian Fang Marco Fargetta Anna Fatkina Dmitry Fedoseev Vladko Fekete Li-Cheng Feng Qichun Feng Richard Ford Andrey Formozov Amélie Fournier Haonan Gan Feng Gao Alberto Garfagnini Alexandre Göttel Christoph Genster Marco Giammarchi Agnese Giaz Nunzio Giudice Franco Giuliani Maxim Gonchar Guanghua Gong Hui Gong Oleg Gorchakov Yuri Gornushkin Marco Grassi Christian Grewing Maxim Gromov Vasily Gromov Minghao Gu Xiaofei Gu Yu Gu Mengyun Guan Nunzio Guardone Maria Gul Cong Guo Jingyuan Guo Wanlei Guo Xinheng Guo Yuhang Guo Paul Hackspacher Caren Hagner Ran Han Yang Han Miao He Wei He Tobias Heinz Patrick Hellmuth Yuekun Heng Rafael Herrera Daojin Hong YuenKeung Hor Shaojing Hou Yee Hsiung Bei-Zhen Hu Hang Hu Jianrun Hu Jun Hu Shouyang Hu Tao Hu Zhuojun Hu Chunhao Huang Guihong Huang Hanxiong Huang Qinhua Huang Wenhao Huang Xingtao Huang Yongbo Huang Jiaqi Hui Wenju Huo Cédric Huss Safeer Hussain Antonio Insolia Ara Ioannisian Daniel Ioannisyan Roberto Isocrate Kuo-Lun Jen Xiaolu Ji Xingzhao Ji Huihui Jia Junji Jia Siyu Jian Di Jiang Xiaoshan Jiang Ruyi Jin Xiaoping Jing Cécile Jollet Jari Joutsenvaara Sirichok Jungthawan Leonidas Kalousis Philipp Kampmann Li Kang Michael Karagounis Narine Kazarian Amir Khan Waseem Khan Khanchai Khosonthongkee Patrick Kinz Denis Korablev Konstantin Kouzakov Alexey Krasnoperov Svetlana Krokhaleva Zinovy Krumshteyn Andre Kruth Nikolay Kutovskiy Pasi Kuusiniemi Tobias Lachenmaier Cecilia Landini Sébastien Leblanc Frederic Lefevre Liping Lei Ruiting Lei Rupert Leitner Jason Leung Demin Li Fei Li Fule Li Haitao Li Huiling Li Jiaqi Li Jin Li Kaijie Li Mengzhao Li Nan Li Nan Li Qingjiang Li Ruhui Li Shanfeng Li Shuaijie Li Tao Li Weidong Li Weiguo Li Xiaomei Li Xiaonan Li Xinglong Li Yi Li Yufeng Li Zhibing Li Ziyuan Li Hao Liang Hao Liang Jingjing Liang Jiajun Liao Daniel Liebau Ayut Limphirat Sukit Limpijumnong Guey-Lin Lin Shengxin Lin Tao Lin Jiajie Ling Ivano Lippi Fang Liu Haidong Liu Hongbang Liu Hongjuan Liu Hongtao Liu Hu Liu Hui Liu Jianglai Liu Jinchang Liu Min Liu Qian Liu Qin Liu Runxuan Liu Shuangyu Liu Shubin Liu Shulin Liu Xiaowei Liu Yan Liu Alexey Lokhov Paolo Lombardi Claudio Lombardo Kai Loo Chuan Lu Haoqi Lu Jingbin Lu Junguang Lu Shuxiang Lu Xiaoxu Lu Bayarto Lubsandorzhiev Sultim Lubsandorzhiev Livia Ludhova Fengjiao Luo Guang Luo Pengwei Luo Shu Luo Wuming Luo Vladimir Lyashuk Qiumei Ma Si Ma Xiaoyan Ma Xubo Ma Jihane Maalmi Yury Malyshkin Fabio Mantovani Francesco Manzali Xin Mao Yajun Mao Stefano MMari Filippo Marini Sadia Marium Cristina Martellini Gisele Martin-Chassard Agnese Martini Davit Mayilyan Axel Müller Ints Mednieks Yue Meng Anselmo Meregaglia Emanuela Meroni David Meyhöfer Mauro Mezzetto Jonathan Miller Lino Miramonti Salvatore Monforte Paolo Montini Michele Montuschi Nikolay Morozov Pavithra Muralidharan Massimiliano Nastasi Dmitry VNaumov Elena Naumova Igor Nemchenok Alexey Nikolaev Feipeng Ning Zhe Ning Hiroshi Nunokawa Lothar Oberauer Juan Pedro Ochoa-Ricoux Alexander Olshevskiy Domizia Orestano Fausto Ortica Hsiao-Ru Pan Alessandro Paoloni Nina Parkalian Sergio Parmeggiano Teerapat Payupol Yatian Pei Nicomede Pelliccia Anguo Peng Haiping Peng Frédéric Perrot Pierre-Alexandre Petitjean Fabrizio Petrucci Luis Felipe Piñeres Rico Oliver Pilarczyk Artyom Popov Pascal Poussot Wathan Pratumwan Ezio Previtali Fazhi Qi Ming Qi Sen Qian Xiaohui Qian Hao Qiao Zhonghua Qin Shoukang Qiu Muhammad Rajput Gioacchino Ranucci Neill Raper Alessandra Re Henning Rebber Abdel Rebii Bin Ren Jie Ren Taras Rezinko Barbara Ricci Markus Robens Mathieu Roche Narongkiat Rodphai Aldo Romani Bedřich Roskovec Christian Roth Xiangdong Ruan Xichao Ruan Saroj Rujirawat Arseniy Rybnikov Andrey Sadovsky Paolo Saggese Giuseppe Salamanna Simone Sanfilippo Anut Sangka Nuanwan Sanguansak Utane Sawangwit Julia Sawatzki Fatma Sawy Michaela Schever Jacky Schuler Cédric Schwab Konstantin Schweizer Dmitry Selivanov Alexandr Selyunin Andrea Serafini Giulio Settanta Mariangela Settimo Muhammad Shahzad Vladislav Sharov Gang Shi Jingyan Shi Yongjiu Shi Vitaly Shutov Andrey Sidorenkov FedorŠimkovic Chiara Sirignano Jaruchit Siripak Monica Sisti Maciej Slupecki Mikhail Smirnov Oleg Smirnov Thiago Sogo-Bezerra Julanan Songwadhana Boonrucksar Soonthornthum Albert Sotnikov Ondrej Sramek Warintorn Sreethawong Achim Stahl Luca Stanco Konstantin Stankevich DušanŠtefánik Hans Steiger Jochen Steinmann Tobias Sterr Matthias Raphael Stock Virginia Strati Alexander Studenikin Gongxing Sun Shifeng Sun Xilei Sun Yongjie Sun Yongzhao Sun Narumon Suwonjandee Michal Szelezniak Jian Tang Qiang Tang Quan Tang Xiao Tang Alexander Tietzsch Igor Tkachev Tomas Tmej Konstantin Treskov Andrea Triossi Giancarlo Troni Wladyslaw Trzaska Cristina Tuve Stefan van Waasen Johannes van den Boom Guillaume Vanroyen Nikolaos Vassilopoulos Vadim Vedin Giuseppe Verde Maxim Vialkov Benoit Viaud Cristina Volpe Vit Vorobel Lucia Votano Pablo Walker Caishen Wang Chung-Hsiang Wang En Wang Guoli Wang Jian Wang Jun Wang Kunyu Wang Lu Wang Meifen Wang Meng Wang Ruiguang Wang Siguang Wang Wei Wang Wenshuai Wang Xi Wang Xiangyue Wang Yangfu Wang Yaoguang Wang Yi Wang Yifang Wang Yuanqing Wang Yuman Wang Zhe Wang Zheng Wang Zhimin Wang Zongyi Wang Apimook Watcharangkool Lianghong Wei Wei Wei Yadong Wei Liangjian Wen Christopher Wiebusch Steven Chan-Fai Wong Bjoern Wonsak Diru Wu Fangliang Wu Qun Wu Wenjie Wu Zhi Wu Michael Wurm Jacques Wurtz Christian Wysotzki Yufei Xi Dongmei Xia Yuguang Xie Zhangquan Xie Zhizhong Xing Benda Xu Donglian Xu Fanrong Xu Jilei Xu Jing Xu Meihang Xu Yin Xu Yu Xu Baojun Yan Xiongbo Yan Yupeng Yan Anbo Yang Changgen Yang Huan Yang Jie Yang Lei Yang Xiaoyu Yang Yifan Yang Haifeng Yao Zafar Yasin Jiaxuan Ye Mei Ye Ugur Yegin Frédéric Yermia Peihuai Yi Xiangwei Yin Zhengyun You Boxiang Yu Chiye Yu Chunxu Yu Hongzhao Yu Miao Yu Xianghui Yu Zeyuan Yu Chengzhuo Yuan Ying Yuan Zhenxiong Yuan Ziyi Yuan Baobiao Yue Noman Zafar Andre Zambanini Pan Zeng Shan Zeng Tingxuan Zeng Yuda Zeng Liang Zhan Feiyang Zhang Guoqing Zhang Haiqiong Zhang Honghao Zhang Jiawen Zhang Jie Zhang Jingbo Zhang Peng Zhang Qingmin Zhang Shiqi Zhang Tao Zhang Xiaomei Zhang Xuantong Zhang Yan Zhang Yinhong Zhang Yiyu Zhang Yongpeng Zhang Yuanyuan Zhang Yumei Zhang Zhenyu Zhang Zhijian Zhang Fengyi Zhao Jie Zhao Rong Zhao Shujun Zhao Tianchi Zhao Dongqin Zheng Hua Zheng Minshan Zheng Yangheng Zheng Weirong Zhong Jing Zhou Li Zhou Nan Zhou Shun Zhou Xiang Zhou Jiang Zhu Kejun Zhu Honglin Zhuang Liang Zong Jiaheng Zou | 2021 | Chinese Physics C2021，45，2： | 0 |
| 15 | Application of silk fibroin coatings for biomaterial surface modification:a silk road for biomedicine显示文摘Silk fibroin(SF)as a natural biopolymer has become a popular material for biomedical applications due to its minimal immunogenicity,tunable biodegradability,and high biocompatibility.Nowadays,various techniques have been developed for the applications of SF in bioengineering.Most of the literature reviews focus on the SF-based biomaterials and their different forms of applications such as films,hydrogels,and scaffolds.SF is also valuable as a coating on other substrate materials for biomedicine;however,there are few reviews related to SF-coated biomaterials.Thus,in this review,we focused on the surface modification of biomaterials using SF coatings,demonstrated their various preparation methods on substrate materials,and introduced the latest procedures.The diverse applications of SF coatings for biomedicine are discussed,including bone,ligament,skin,mucosa,and nerve regeneration,and dental implant surface modification.SF coating is conducive to inducing cell adhesion and migration,promoting hydroxyapatite(HA)deposition and matrix mineralization,and inhibiting the Notch signaling pathway,making it a promising strategy for bone regeneration.In addition,SF-coated composite scaffolds can be considered prospective candidates for ligament regeneration after injury.SF coating has been proven to enhance the mechanical properties of the substrate material,and render integral stability to the dressing material during the regeneration of skin and mucosa.Moreover,SF coating is a potential strategy to accelerate nerve regeneration due to its dielectric properties,mechanical flexibility,and angiogenesis promotion effect.In addition,SF coating is an effective and popular means for dental implant surface modification to promote osteogenesis around implants made of different materials.Thus,this review can be of great benefit for further improvements in SF-coated biomaterials,and will undoubtedly contribute to clinical transformation in the future. | Jinxing HU Zhiwei JIANG Jing ZHANG Guoli YANG | 2023 | Journal of Zhejiang University-Science B(Biomedicine & Biotechnology)2023，24，11： | 0 |
| 16 | Screening and Assessing 11 Mycobacterium tuberculosis Proteins as Potential Serodiagnostical Markers for Discriminating TB Patients from BCG Vaccinees显示文摘Purified protein derivative (PPD) skin tests often yield poor specificity, so that to develop new serological antigens for distinguishing between Mycobacterium tuberculosis infection and Bacille Calmette-Guerin (BCG) vaccination is a priority, especially for developing countries like China. We predicted the antigenicity for selected open reading frames (ORFs) based on the genome sequences of M. tuberculosis H37Rv and M. bovis BCG, as well as their functions and differences of expression under different stimulus. The candidate ORFs were cloned from H37Rv sequences and expressed as recombinant proteins in Escherichia coli. We studied the serodiagnostic potential of 11 purified recombinants by using enzyme-linked immunosorbent assay (ELISA) and involving a cohort composed of 58 TB patients (34 males and 24 females), 8 healthy volunteers and 50 PPD-negative individuals before and after BCG vaccination. For all the 11 antigens, the median OD values for the sera from TB patients were statistically significantly higher than those for PPD-negative individuals before or after BCG vaccination (P<0.01). They had at least 92% specificity in healthy controls and six seroantigens (Rv0251c, Rv1973, Rv2376c, Rv2537c, Rv2785c and Rv3873A) were never reported with seroantigenicities previously. Thus the approach combining comparative genomics, bioinformatics and ELISA techniques can be employed to identify new seroantigens distinguishing M. tuberculosis infection from BCG vaccination. | Guoqiang Zhang Lingxia Zhang Mingcheng Zhang Linlin Pan Fengyu Wang Jun Huang Guoli Li Jun Yu Songnian Hu | 2009 | Genomics, Proteomics & Bioinformatics2009，7，3： | 0 |
| 17 | Human-pose estimation based on weak supervision显示文摘Background In computer vision,simultaneously estimating human pose,shape,and clothing is a practical issue in real life,but remains a challenging task owing to the variety of clothing,complexity of de-formation,shortage of large-scale datasets,and difficulty in estimating clothing style.Methods We propose a multistage weakly supervised method that makes full use of data with less labeled information for learning to estimate human body shape,pose,and clothing deformation.In the first stage,the SMPL human-body model parameters were regressed using the multi-view 2D key points of the human body.Using multi-view information as weakly supervised information can avoid the deep ambiguity problem of a single view,obtain a more accurate human posture,and access supervisory information easily.In the second stage,clothing is represented by a PCA-based model that uses two-dimensional key points of clothing as supervised information to regress the parameters.In the third stage,we predefine an embedding graph for each type of clothing to describe the deformation.Then,the mask information of the clothing is used to further adjust the deformation of the clothing.To facilitate training,we constructed a multi-view synthetic dataset that included BCNet and SURREAL.Results The Experiments show that the accuracy of our method reaches the same level as that of SOTA methods using strong supervision information while only using weakly supervised information.Because this study uses only weakly supervised information,which is much easier to obtain,it has the advantage of utilizing existing data as training data.Experiments on the DeepFashion2 dataset show that our method can make full use of the existing weak supervision information for fine-tuning on a dataset with little supervision information,compared with the strong supervision information that cannot be trained or adjusted owing to the lack of exact annotation information.Conclusions Our weak supervision method can accurately estimate human body size,pose,and several common types of clothing and overcome the issues of the current shortage of clothing data. | Xiaoyan HU Xizhao BAO Guoli WEI Zhaoyu LI | 2023 | Virtual Reality & Intelligent Hardware2023，5，4： | 0 |
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