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| 1 | Active phase compensation of quantum key distribution system显示文摘Quantum key distribution (QKD) system must be robust enough in practical communication. Besides birefringence of fiber, system performance is notably affected by phase drift. The Faraday-Michelson QKD system can auto-compensate the birefringence of fiber, but phase shift is still a serious problem in its practical operation. In this paper, the major reason of phase drift and its effect on Faraday- Michel- son QKD system is analyzed and an effective active phase compensation scheme is proposed. By this means, we demonstrate a quantum key distribution system which can stably run over 37-km fiber in practical working condition with the long-time averaged quantum bit error rate of 1.59% and the stan- dard derivation of 0.46%. This result shows that the active phase compensation scheme is suitable to be used in practical QKD systems based on double asymmetric interferometers without additional de- vices and thermal controller. | CHEN Wei HAN ZhengFu MO XiaoFan XU FangXing WEI Guo GUO GuangCan | 2008 | Chinese Science Bulletin2008,53,9: | 24 |
| 2 | Insight-HXMT observations of the first binary neutron star merger GW170817显示文摘Finding the electromagnetic(EM) counterpart of binary compact star merger, especially the binary neutron star(BNS) merger,is critically important for gravitational wave(GW) astronomy, cosmology and fundamental physics. On Aug. 17, 2017,Advanced LIGO and Fermi/GBM independently triggered the first BNS merger, GW170817, and its high energy EM counterpart,GRB 170817 A, respectively, resulting in a global observation campaign covering gamma-ray, X-ray, UV, optical, IR, radio as well as neutrinos. The High Energy X-ray telescope(HE) onboard Insight-HXMT(Hard X-ray Modulation Telescope) is the unique high-energy gamma-ray telescope that monitored the entire GW localization area and especially the optical counterpart(SSS17 a/AT2017 gfo) with very large collection area(~1000 cm^2) and microsecond time resolution in 0.2-5 MeV. In addition,Insight-HXMT quickly implemented a Target of Opportunity(ToO) observation to scan the GW localization area for potential X-ray emission from the GW source. Although Insight-HXMT did not detect any significant high energy(0.2-5 MeV) radiation from GW170817, its observation helped to confirm the unexpected weak and soft nature of GRB 170817 A. Meanwhile,Insight-HXMT/HE provides one of the most stringent constraints(~10^(-7) to 10^(-6) erg/cm^2/s) for both GRB170817 A and any other possible precursor or extended emissions in 0.2-5 MeV, which help us to better understand the properties of EM radiation from this BNS merger. Therefore the observation of Insight-HXMT constitutes an important chapter in the full context of multi-wavelength and multi-messenger observation of this historical GW event. | TiPei Li ShaoLin Xiong ShuangNan Zhang FangJun Lu LiMing Song XueLei Cao Zhi Chang Gang Chen Li Chen TianXiang Chen Yong Chen YiBao Chen YuPeng Chen Wei Cui WeiWei Cui JingKang Deng YongWei Dong YuanYuan Du MinXue Fu GuanHua Gao He Gao Min Gao MingYu Ge YuDong Gu Ju Guan ChengCheng Guo DaWei Han Wei Hu Yue Huang Jia Huo ShuMei Jia LuHua Jiang WeiChun Jiang Jing Jin YongJie Jin Bing Li ChengKui Li Gang Li MaoShun Li Wei Li Xian Li XiaoBo Li XuFang Li YanGuo Li ZiJian Li ZhengWei Li XiaoHua Liang JinYuan Liao CongZhan Liu GuoQing Liu HongWei Liu ShaoZhen Liu XiaoJing Liu Yuan Liu YiNong Liu Bo Lu XueFeng Lu Tao Luo Xiang Ma Bin Meng Yi Nang JianYin Nie Ge OU JinLu Qu Na Sai Liang Sun Yin Tan Lian Tao WenHui Tao YouLi Tuo GuoFeng Wang HuanYu Wang Juan Wang WenShuai Wang YuSa Wang XiangYang Wen BoBing WU Mei Wu GuangCheng Xiao He Xu YuPeng Xu LinLi Yan JiaWei Yang Sheng Yang YanJi Yang AiMei Zhang ChunLei Zhang ChengMo Zhang Fan Zhang HongMei Zhang Juan Zhang Qiang Zhang Shu Zhang Tong Zhang Wei Zhang WanChang Zhang WenZhao Zhang Yi Zhang Yue Zhang YiFei Zhang YongJie Zhang Zhao Zhang ZiLiang Zhang HaiSheng Zhao JianLing Zhao XiaoFan Zhao ShiJie Zheng Yue Zhu YuXuan Zhu ChangLin Zou | 2018 | Science China(Physics,Mechanics & Astronomy)2018,61,3: | 12 |
| 3 | The Low Energy X-ray telescope (LE) onboard the Insight-HXMT astronomy satellite显示文摘The Low Energy X-ray telescope(LE) is one of the three main instruments of the Insight-Hard X-ray Modulation Telescope(Insight-HXMT). It is equipped with Swept Charge Device(SCD) sensor arrays with a total geometrical area of 384 cm^2 and an energy band from 0.7 to 13 ke V. In order to evaluate the particle induced X-ray background and the cosmic X-ray background simultaneously, LE adopts collimators to define four types of Field Of Views(FOVs), i.e., 1.6°×6°, 4°×6°, 50°-60°×2°-6 oand the blocked ones which block the X-ray by an aluminum cover. LE is constituted of three detector boxes(LEDs) and an electric control box(LEB) and achieves a good energy resolution of 140 e V@5.9 ke V, an excellent time resolution of 0.98 ms, as well as an extremely low pileup(<1%@18000 cts/s). Detailed performance tests and calibration on the ground have been performed,including energy-channel relation, energy response, detection efficiency and time response. | Yong Chen WeiWei Cui Wei Li Juan Wang YuPeng Xu FangJun Lul YuSa Wang TianXiang Chen DaWei Han Wei Hu Yi Zhang Jia Huo YanJi Yang MaoShun Li Bo Lu ZiLiang Zhang TiPei Li ShuangNan Zhang ShaoLin Xiong Shu Zhang RongFeng Xue XiaoFan Zhao Yue Zhu YuXuan Zhu HongWei Liu YiJung Yang Fan Zhang | 2020 | Science China(Physics,Mechanics & Astronomy)2020,63,4: | 8 |
| 4 | The critical rate of horizontal wells in bottom-water reservoirs with an impermeable barrier显示文摘Barrier impacts on water cut and critical rate of horizontal wells in bottom water-drive reservoirs have been recognized but not investigated quantitatively. Considering the existence of impermeable barriers in oil formations, this paper developed a horizontal well flow model and obtained mathematical equations for the critical rate when water cresting forms in bottom-water reservoirs. The result shows that the barrier increases the critical rate and delays water breakthrough. Further study of the barrier size and location shows that increases in the barrier size and the distance between the barrier and oil-water contact lead to higher critical rates. The critical rate gradually approaches a constant as the barrier size increases. The case study shows the method presented here can be used to predict the critical rate in a bottom-water reservoir and applied to investigate the water cresting behavior of horizontal wells. | Yue Ping Du Zhimin Chen Xiaofan Liang Baosheng | 2012 | Petroleum Science2012,9,2: | 6 |
| 5 | A novel lineage of osteoprogenitor cells with dual epithelial and mesenchymal properties govern maxillofacial bone homeostasis and regeneration after MSFL显示文摘Bone regeneration originates from proliferation and differentiation of osteoprogenitors via either endochondral or intramembranous ossifcation;and the regeneration capacities decline with age and estrogen loss.Maillary sinus floor lifting(MSFL)is a commonly used surgical procedure for guiding bone regeneration in mailla.Radiographic analysis of 1210 clinical cases of maxilla bone regeneration after MSFL revealed that the intrasinus osteogenic eficacy was independent of age and gender,however;and this might be related to the Schneiderian membrane that lines the sinus cavity.In view of the particularity of this biological process,our present study aimed to elucidate the underlying mechanism of MSFL-induced bone regeneration.We frst established a murine model to simulate the clinical MSFL.By single cell RNA-sequencing and flow cytometry-based bulk RNA-sequencing,we identifed a novel Krt14^(+)Ctsk^(+)subset of cells that display both epithelial and mesenchymal properties and the transcriptomic feature of osteoprogenitors.Dual recombinases-mediated lineage tracing and oss-offunction analyses showed that these Krt14^(+)Ctsk^(+)progenitors contribute to both MSFL-induced osteogenesis and physiological bone homeostasis by differentiating into Krt14 Ctsk^(+)descendants which show robust osteogenic capacity.In addition,we detected a similar population of Kt14^(+)Ctsk^(+)cells in human samples of Schneiderian membrane,which show a highly similar osteogenic potential and transcriptomic feature to the corresponding cells in mice.The identifcation of this Krt14^(+)Ctsk^(+)population,featured by osteoprogenitor charateristics and dual epithelial-mesenchymal properties,provides new insight into the understanding of bone regeneration and may open more possibilities for clinical applications. | Yuteng Weng Haicheng Wang Di Wu Shuyu Xu Xiaofan Chen Jie Huang Yanhuizhi Feng Lin Li Zuolin Wang | 2022 | Cell Research2022,32,9: | 5 |
| 6 | Chaiqin Chengqi decoction inhibits inflammatory mediators and attenuates acute pancreatitis through deactivation of janus kinase/signal transducer and activator of transcription signaling pathway显示文摘OBJECTIVE: To investigate the effect of Chaiqin Chengqi decoction(CQCQD) on acute pancreatitis(AP) by janus kinase/signal transducer and activator of transcription(JAK/STAT) signaling pathway in vitro and in vivo.METHODS: AP was induced by caerulein both in AR42J cells and in mice. AR42J cells were divided into five groups: the control group, the AP group, the CQCQD group, JAK/STAT signaling pathway inhibitor AG490 group, and the CQCQD and AG490 group.After induction, cellular supernatant of five groups were collected for measuring the concentrations of inflammatory cytokine amylase, interleukin 6(IL-6),tumor necrosis factor α(TNF-α), interleukin 1β(IL-1β), nuclear factor κB(NF-κB) by enzyme-linked immunosorbent assay and the expression of JAK-2,STAT-3 signaling transduction proteins by Western blot, respectively. Experiments in mice were performed similar to that of in AR42J cells.RESULTS: Treatment of AR42J cells with CQCQD reduced the pancreatic injury and negatively regulated the activities of amylase, as well as inhibited expression of several inflammatory cytokines such as IL-6, TNF-α, IL-1β, NF-κB. Administration of CQCQD significantly inhibited JAK-2 activation and down-regulated phosphorylation of downstream substrate STAT-3 the same as AG490, resulting in inhibition of inflammatory mediators and amelioration of pancreatitis.CONCLUSION: The results suggested that CQCQD exerted anti-inflammatory effects on AP via reducing expression and phosphorylation of JAK and STAT. | Dong Jianxia Chen Xiaoshuang Song Yi Fei Xiaofan | 2019 | Journal of Traditional Chinese Medicine2019,39,2: | 5 |
| 7 | Anti-PD-L1/TGF-BR fusion protein (SHR-1701) overcomes disrupted lymphocyte recovery-induced resistance to PD-1/PD-L1 inhibitors in lung cancer显示文摘Background:Second-generation programmed cell death-protein 1/pro-grammed death-ligand 1(PD-1/PD-L1)inhibitors,such as bintrafusp alfa(M7824),SHR-1701,and YM101,have been developed to simultaneously block PD-1/PD-L1 and transforming growth factor-beta/transforming growth factor-beta receptor(TGF-P/TGF-βR).Consequently,it is necessary to identify predictive factors of lung cancer patients who are not only resistant to PD-1/PD-LI inhibitors but also sensitive to bifunctional drugs.The purpose of this study was to search for such predictors.Methods:Multivariable Cox regression was used to study the association between the clinical outcome of treatment with PD-1/PD-L1 inhibitors and lym-phocyte recovery after lymphopenia in lung cancer patients.Murine CMT167 lung cancer cells were engineered to express the firefly luciferase gene and implanted orthotopically in the lung of syngeneic mice.Bioluminescence imag-ing,flow cytometry,and immunohistochemistry were employed to detrmine response to immunotherapy and function of tumor-infiltrating immune cells.Results:For lung cancer patients treated with anti-PD-1/PD-LI antibodies,poor lymphocyte recovery was associated with a shorter progression-free survival(PFS;P<0.001),an accumulation of regulatory T cells(Tregs),and an elimi-nation of CD8+T cells in the peripheral blood.Levels of CD8+T cells and Treg cells were also imbalanced in the tumors and peripheral immune organs of mice with poor lymphocyte recovery after chemotherapy.Moreover,these mice failed to respond to anti-PD-1 antibodies but remained sensitive to the anti-PD-LI/TGF-βR fusion protein(SHR-1701).Consistently,SHR-1701 but not anti-PD-1 antibod-ies,markedly enhanced IFN-γproduction and Ki-67 expression in peripheral CD8+T cells from patients with impaired lymphocyte recovery.Conclusions:Lung cancer patients with poor lymphocyte recovery and suffer-ing from persistent lymphopenia after previous chemotherapy are resistant to anti-PD-1/PD-L1 antibodies but might be sensitive to second-generation agents such as SHR-1701. | Bo Cheng Kaikai Ding Pengxiang Chen Jianxiong Ji Tao Luo Xiaofan Guo Wei Qiu Chunhong Ma Xue Meng Jian Wang Jinming Yu Yuan Liu | 2022 | Cancer Communications2022,42,1: | 5 |
| 8 | Flame-retardant quasi-solid polymer electrolyte enabling sodium metal batteries with highly safe characteristic and superior cycling stability显示文摘Con ventio nal liquid electrolytes based sodium metal batteries suffer from severe safety hazards owing to electrolyte leakage,in flammability and dendritic sodium deposit!on.Herein,we report a flame-retardant quasi-solid polymer electrolyte with poly(methyl vinyl ether-alt-maleic an hydride)(P(MVE-alt-MA))as host,bacterial cellulose(BC)as reinforceme nt,and triethyl phosphate/vinyle ne carb on ate/sodium perchlorate(TEP/VC/NaClO4)as plasticizer for highly safe sodium metal batteries.The as-obtained quasi-solid polymer electrolyte exhibits superior flame retardancy(self-extinguish within 1 s),complete non-leakage property and wide electrochemical windows(4.4 V).More importantly,Na3V2(PO4)3/Na metal batteries using such polymer electrolyte delivers superior I on g-term cycli ng stability(84.4%capacity rete ntion after 1000 cycles)which is significantly better than that(only 2%after 240 cycles)of liquid electrolyte.In addition,this flame-retardant quasi-solid polymer electrolyte provides favorable cycle performance(80.2%capacity retention after 70 cycles at 50°C and 84.8%capacity retention after 50 cycles at-10°C)for Na3V2(PO4)3/Na metal batteries.And this battery also displayed a normal charge/discharge property even at-15°C.These fascinating cycle properties are mainly ascribed to the effective pro怕ctive layers formed on Na3V2(PC>4)3 cathode and sodium metal ano de.More thorough in vestigati on elucidates that such flame-retardant quasi-solid polymer electrolyte plays a multif unctional role in the adva need sodium metal batteries:(1)being in volved in the formatio n of a favorable cathode electrolyte in terface(CEI)to inhibit the dissolutio n of van adium and maintai n the structure integrity of the Na3V2(PO4)3;(2)participati ng in building a stable solid electrolyte in terface(SEI)to suppress the growth of Na dendrites;(3)integrating flame-retardanee into polymer sodium batteries to enhance flame-resistanee,eliminate electrolyte leakage,and thus improve safety of sodium batteries.Based on these results,we further assembled Na3V2(PO4)3/MoS2 pouch cell which can withsta nd harsh conditions(be nded or cut off a corn er),confirming the obtai ned polymer electrolyte with superior non-leakage property.In all,these outstanding characteristics would endow this flame-retardant quasi-solid polymer electrolyte a very promising can didate for highly-safe sodium metal batteries. | Jinfeng Yang Min Zhang Zheng Chen Xiaofan Du Suqi Huang Ben Tang Tiantian Dong Han Wu Zhe Yu Jianjun Zhang Guanglei Cui | 2019 | Nano Research2019,12,9: | 4 |
| 9 | Active tension optimal control for WT wheelchair robot by using a novel control law for holonomic or nonholonomic systems显示文摘The characteristics of interaction between WT wheelchair robot and stair environments is analyzed and possible patterns of WT wheelchair robot during the stair-climbing process are summarized, with criteria to determine the pattern of the wheelchair robot proposed. Aiming at the complicated mechanism of WT wheelchair robot with holonomic constraints and combining it with the dynamic programming, namely the Hamilton-Jacobi equation, a new control law called active tension optimal control is presented for holonomic or nonholonomic robotic systems, based on which one can make the wheelchair robot with a holonomic or nonholonomic mechanism track the expected reference input of constraint forces of holonomic or nonholinomic constraints as well as track the expected reference input of the generalized coordinate of each joint. The module STATEFLOW in MATLAB is used to simulate the entire stair-climbing process of WT wheelchair robot, and comparison is made between the output curves of each joint and the tension of the track and the expected reference input curves, which verifies the effectiveness of the proposed control law. | WANG Jian WANG Ting YAO Chen LI XiaoFan WU ChengDong | 2014 | Science China(Information Sciences)2014,57,11: | 3 |
| 10 | Overview to the Hard X-ray Modulation Telescope (Insight-HXMT) Satellite显示文摘As China’s first X-ray astronomical satellite, the Hard X-ray Modulation Telescope (HXMT), which was dubbed as Insight-HXMT after the launch on June 15, 2017, is a wide-band(1-250 ke V) slat-collimator-based X-ray astronomy satellite with the capability of all-sky monitoring in 0.2-3 Me V. It was designed to perform pointing, scanning and gamma-ray burst(GRB)observations and, based on the Direct Demodulation Method (DDM), the image of the scanned sky region can be reconstructed.Here we give an overview of the mission and its progresses, including payload, core sciences, ground calibration/facility, ground segment, data archive, software, in-orbit performance, calibration, background model, observations and some preliminary results. | Shuang-Nan Zhang TiPei Li FangJun Lu LiMing Song YuPeng X u CongZhan Liu Yong Chen XueLei Cao QingCui Bu Zhi Chang Gang Chen Li Chen TianXiang Chen YiBao Chen YuPeng Chen Wei Cui WeiWei Cui JingKang Deng YongWei Dong Yuan Yuan Du MinXue Fu GuanHua Gao He Gao Min Gao MingYu Ge YuDong Gu Ju Guan Can Gungor ChengCheng Guo DaWei Han Wei Hu Yue Huang Jia Huo ShuMei Jia LuHua Jiang WeiChun Jiang Jing Jin YongJie Jin Bing Li ChengKui Li Gang Li MaoShun Li Wei Li Xian Li XiaoBo Li XuFang Li YanGuo Li ZiJian Li ZhengWei Li XiaoHua Liang JinYuan Liao GuoQing Liu HongWei Liu ShaoZhen Liu XiaoJing Liu Yuan Liu YiNong Liu Bo Lu XueFeng Lu Tao Luo Xiang Ma Bin Meng Yi Nang JianYin Nie Ge Ou JinLu Qu Na Sai RenCheng Shang GuoHong Shen Liang Sun Ying Tan Lian Tao YouLi Tuo Chen Wang ChunQin Wang GuoFeng Wang HuanYu Wang Juan Wang WenShuai Wang YuSa Wang XiangYang Wen BaiYang Wu BoBing Wu Mei Wu GuangCheng Xiao ShaoLin Xiong LinLi Yan JiaWei Yang Sheng Yang YanJi Yang QiBin Yi Bin Yuan AiMei Zhang ChunLei Zhang ChengMo Zhang Fan Zhang HongMei Zhang Juan Zhang Qiang Zhang ShenYi Zhangs Shu Zhang Tong Zhang WanChang Zhang Wei Zhang WenZhao Zhang Yi Zhang YiFei Zhang YongJie Zhang Yue Zhang Zhao Zhang Zhi Zhang ZiLiang Zhang HaiSheng Zhao XiaoFan Zhao ShiJie Zheng JianFeng Zhou YuXuan Zhu Yue Zhu RenLin Zhuang | 2020 | Science China(Physics,Mechanics & Astronomy)2020,63,4: | 2 |
| 11 | Towards carbon neutrality:A study on China's long-term low-carbon transition pathways and strategies显示文摘As the world's biggest carbon dioxide(CO_(2))emitter and the largest developing country,China faces daunting challenges to peak its emissions before 2030 and achieve carbon neutrality within 40 years.This study fully considered the carbon-neutrality goal and the temperature rise constraints required by the Paris Agreement,by developing six long-term development scenarios,and conducting a quantitative evaluation on the carbon emissions pathways,energy transformation,technology,policy and investment demand for each scenario.This study combined both bottom-up and top-down methodologies,including simulations and analyses of energy consumption of end-use and power sectors(bottom-up),as well as scenario analysis,investment demand and technology evaluation at the macro level(top-down).This study demonstrates that achieving carbon neutrality before 2060 translates to significant efforts and overwhelming challenges for China.To comply with the target,a high rate of an average annual reduction of CO_(2) emissions by 9.3%from 2030 to 2050 is a necessity,which requires a huge investment demand.For example,in the 1.5℃ scenario,an investment in energy infrastructure alone equivalent to 2.6%of that year's GDP will be necessary.The technological pathway towards carbon neutrality will rely highly on both conventional emission reduction technologies and breakthrough technologies.China needs to balance a long-term development strategy of lower greenhouse gas emissions that meets both the Paris Agreement and the long-term goals for domestic economic and social development,with a phased implementation for both its five-year and long-term plans. | Jiankun He Zheng Li Xiliang Zhang Hailin Wang Wenjuan Dong Ershun Du Shiyan Chang Xunmin Ou Siyue Guo Zhiyu Tian Alun Gu Fei Teng Bin Hu Xiu Yang Siyuan Chen Mingtao Yao Zhiyi Yuan Li Zhou Xiaofan Zhao Ying Li Danwei Zhang | 2022 | Environmental Science and Ecotechnology2022,,1: | 2 |
| 12 | Complex Networks: Small-world, Scale-free and Beyond显示文摘 | Wang Xiaofan Chen Guanrong | 2003 | IEEE Circuits and Systems Magazine2003,3,1: | 1 |
| 13 | Complex networks small-world scale-free and beyond显示文摘 | Wang Xiaofan Chen Guanrong | 2003 | IEEE Circuits and Systems Magaxine2003,3,1: | 1 |
| 14 | An information-centric energy infrastructure: The Berkeley view显示文摘 | Randy H. Katz David E. Culler Seth Sanders Sara Alspaugh Yanpei Chen Stephen Dawson-Haggerty Prabal Dutta Mike He Xiaofan Jiang Laura Keys Andrew Krioukov Ken Lutz Jorge Ortiz Prashanth Mohan Evan Reutzel Jay Taneja Jeff Hsu Sushant Shankar | 2010 | Sustainable Computing: Informatics and Systems2010,,1: | 1 |
| 15 | Synchronization in small-world dynamical networks 显示文摘 | Wang Xiaofan Chen Guanrong | 2002 | Int J Bifurcation and Chaos2002,12,1: | 1 |
| 16 | Synchronization in scale-free dynamical networks:robustness and fragility 显示文摘 | Wang Xiaofan Chen Guanrong | 2002 | IEEE Transactions on Circuits and Systems I:Fundamental Theory and Applications2002,49,1: | 1 |
| 17 | Comparative pharmacokinetics of baicalin and wogonoside by liquid chromatography–mass spectrometry after oral administration of Xiaochaihu Tang and Radix scutellariae extract to rats显示文摘 | Zhenyu Zhu Liang Zhao Xiaofan Liu Jun Chen Hai Zhang Guoqing Zhang Yifeng Chai | 2010 | Journal of Chromatography B2010,,24: | 1 |
| 18 | Pinning control of scale-free dynamical networks 显示文摘 | Wang Xiaofan Chen Guanrong | 2002 | Physica A : Statistical Mechanics and its Applications2002,310,34: | 1 |
| 19 | Propagation of computer virus under the influnce of external computers: A dynamical model 显示文摘 | Chen Jingyun Yang Xiaofan Gan Chenquan | 2013 | Journal of Information & Computational Science2013,10,16: | 1 |
| 20 | Complex networks: small-world, scale-free, and beyond显示文摘 | Chen Guanrong | 2003 | IEEE Circuits and Systems Magazine2003,3,2: | 1 |