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| 1 | Signature motif-guided identification of receptors for peptide hormones essential for root meristem growth显示文摘发信号的调停肽的 cell-to-cell 在植物在细胞的功能的协作和定义有关键角色。肽受体匹配为理解位于调停肽的发信号下面的机制是重要的。这里,我们报导根分裂组织生长的指导结构的鉴定为植物开发重要的因素(RGF ) 受体。基于签名 ligand 识别,主题(Arg-x-Arg ) 在充满白氨酸的重复受体 kinases (LRR-RKs ) 的一个亚科保存了的试金识别了机能上地 uncharacterized LRR-RK At4g26540 作为 RGF1 (RGFR1 ) 的受体。我们进一步在 2.6 Å 的一个决定与 RGFR1 的 LRR 领域在建筑群解决了 RGF1 的水晶结构;,它表明 Arg-x-Gly-Gly (RxGG ) 主题为由 RGFR1 的 RGF1 的硫酸盐组的特定的识别负责。基于 RxGG 主题,我们识别了另外四 RGFR。在导致 RGF 的发信号的五 RGFR 的参予被生物化学、基因的数据支持。我们也提供证明 SERK 为 RGF 作为合作受体工作的证据。一起拿,我们的学习识别 RGF 受体,能连接 RGF 的合作受体与他们的下游的部件发信号并且为与他们的肽 ligands 的 LRR-RKs 的基于结构的匹配提供原则的一个证明。 | Wen Song Li Liu Jizong Wang Zhen Wu Heqiao Zhang Jiao Tang Guangzhong Lin Yichuan Wang Xing Wen Wenyang Li Zhifu Han Hongwei Guo Jijie Chai | 2016 | Cell Research2016，26，6： | 20 |
| 2 | Robust Multiclass Classification for Learning from Imbalanced Biomedical Data显示文摘Imbalanced data is a common and serious problem in many biomedical classification tasks. It causes a bias on the training of classifiers and results in lower accuracy of minority classes prediction. This problem has attracted a lot of research interests in the past decade. Unfortunately, most research efforts only concentrate on 2-class problems. In this paper, we study a new method of formulating a multiclass Support Vector Machine (SVM) problem for imbalanced biomedical data to improve the classification performance. The proposed method applies cost-sensitive approach and ramp loss function to the Crammer and Singer multiclass SVM formulation. Experimental results on multiple biomedical datasets show that the proposed solution can effectively cure the problem when the datasets are noisy and highly imbalanced. | Piyaphol Phoungphol Yanqing Zhang Yichuan Zhao | 2012 | Tsinghua Science and Technology2012，17，6： | 6 |
| 3 | SnO2-based electron transporting layer materials for perovskite solar cells: A review of recent progress显示文摘In recent years, due to their high photo-to-electric power conversion efficiency(PCE)(up to 23%(certified)) and low cost, perovskite solar cells(PSCs) have attracted a great deal of attention in photovoltaics field. The high PCE can be attributed to the excellent physical properties of organic–inorganic hybrid perovskite materials, such as a long charge diffusion length and a high absorption coefficient in the visible range. There are different diffusion lengths of holes in electrons in a PSC device, and thus the electron transporting layer(ETL) plays a critical role in the performance of PSCs. An alternative for TiO2, to the most common ETL material is SnO2, which has similar physical properties to TiO2 but with much higher electron mobility, which is beneficial for electron extraction. In addition, there are many facile methods to fabricate SnO2 nanomaterials with low cost and low energy consumption. In this review paper, we focus on recent developments in SnO2 as the ETL of PSCs. The fabrication methods of SnO2 materials are briefly introduced. The influence of multiple Sn O2 types in the ETL on the performance of PSCs is then reviewed. Different methods for improving the PCE and long-term stability of PSCs based on SnO2 ETL are also summarized. The review provides a systematic and comprehensive understanding of the influence of different Sn O2 ETL types on PSC performance and potentially motivates further development of PSCs with an extension to SnO2-based PSCs. | Yichuan Chen Qi Meng Linrui Zhang Changbao Han Hongli Gao Yongzhe Zhang Hui Yan | 2019 | Journal of Energy Chemistry2019，28，8： | 6 |
| 4 | The landscape of aging显示文摘Aging is characterized by a progressive deterioration of physiological integrity,leading to impaired functional ability and ultimately increased susceptibility to death.It is a major risk factor for chronic human diseases,including cardiovascular disease,diabetes,neurological degeneration,and cancer.Therefore,the growing emphasis on “healthy aging” raises a series of important questions in life and social sciences.In recent years,there has been unprecedented progress in aging research,particularly the discovery that the rate of aging is at least partly controlled by evolutionarily conserved genetic pathways and biological processes.In an attempt to bring full-fledged understanding to both the aging process and age-associated diseases,we review the descriptive,conceptual,and interventive aspects of the landscape of aging composed of a number of layers at the cellular,tissue,organ,organ system,and organismal levels. | Yusheng Cai Wei Song Jiaming Li Ying Jing Chuqian Liang Liyuan Zhang Xia Zhang Wenhui Zhang Beibei Liu Yongpan An Jingyi Li Baixue Tang Siyu Pei Xueying Wu Yuxuan Liu Cheng-Le Zhuang Yilin Ying Xuefeng Dou Yu Chen Fu-Hui Xiao Dingfeng Li Ruici Yang Ya Zhao Yang Wang Lihui Wang Yujing Li Shuai Ma Si Wang Xiaoyuan Song Jie Ren Liang Zhang Jun Wang Weiqi Zhang Zhengwei Xie Jing Qu Jianwei Wang Yichuan Xiao Ye Tian Gelin Wang Ping Hu Jing Ye Yu Sun Zhiyong Mao Qing-Peng Kong Qiang Liu Weiguo Zou Xiao-Li Tian Zhi-Xiong Xiao Yong Liu Jun-Ping Liu Moshi Song Jing-Dong J.Han Guang-Hui Liu | 2022 | Science China(Life Sciences)2022，65，12： | 4 |
| 5 | Evaluation of urban river landscape design rationality based on AHP显示文摘An evaluation model for the rationality of the landscape design of urban rivers was established with the analytic hierarchy process (AHP) method so as to provide a foundation for updating the landscape design of urban rivers. The evaluation system was divided into four layers, including the target layer, the comprehensive layer, the element layer, and the index layer. Each layer was made of different indices. The evaluation standards for each index were also given in this paper. This evaluation model was proved tenable through its application to the landscape design rationality evaluation of the Weihe River in Xinxiang City of Henan Province. The results show that the water quality, space, activity, facility, community, width of vegetation, sense of beauty and water content are among the most influential factors and should be considered the main basis for evaluating the rationality of the landscape design of urban rivers. | Qiao Lifang Zhang Yichuan Cao Wei | 2008 | Water Science and Engineering2008，1，4： | 4 |
| 6 | Carbon and carbon composites for thermoelectric applications显示文摘The urgent need for consistent,reliable,ecofriendly,and stable power sources drives the development of new green energy materials.Thermoelectric(TE)materials receive increasing attention due to their unique capability of realizing the direct energy conversion between heat and electricity,showing diverse applications in harvesting waste heat and low-grade heat.Carbon materials such as carbon nanotubes(CNTs)and graphene have experienced a rapid development as TE materials because of their intrinsic ultrahigh electrical conductivity and light weight.Besides,polymer-based carbon composites are particularly fascinating as the combination of the merits of polymers and filler materials leads to high TE performance and superior flexibility.Herein,the recent TE advances are systematically summarized in the studied popularity of carbon materials(ie,CNTs and graphene)and the category of polymers.The conducting polymer-based carbon materials are particularly highlighted.Finally,the remaining challenges and some tentative suggestions possibly guiding future developments are proposed,which may pave a way for a bright future of carbon and carbon composites in the energy market. | Yichuan Zhang Qichun Zhang Guangming Chen | 2020 | Carbon Energy2020，2，3： | 4 |
| 7 | Toward improved trade-off between thermoelectric and mechanical performances in polycarbonate/single-walled carbon nanotube composite films显示文摘Polymer thermoelectric(TE)composites have witnessed explosive developments in recent years,arising from their promising prospect for lightweight flexible electronics and capability of harvesting waste-heat.In sharp contrast with intrinsically conducting polymers(CPs),the insulating thermoplastics have seldom been employed as the matrices for flexible TE composites despite their advantages of low costs,controllable melt-flowing behaviors and excellent mechanical properties.Here,we report flexible films of polycarbonate/single-walled carbon nanotube(PC/SWCNT)composites with improved trade-off between TE and mechanical performances.The SWCNTs with 1D nanostructure were dramatically aligned by PC melt-flowing under hot-pressing in the radial direction.The composite maximum power factor reaches 4.8±0.8μW m^(−1) K^(−2) at 10 wt%SWCNTs in the aligned direction,which is higher than most previously reported thermoplastics-based TE composites at the same SWCNT loading and even comparable to some intrinsically CPs and their composites.In addition,these composites display significantly higher tensile modulus and strength than CPs and their composites.This study paves an effective way to fabricate flexible films of polymer composites with simultaneously high TE and mechanical performances via judicious alignment of SWCNTs in thermoplastic polymers. | Yichuan Zhang Liang Deng Haicai Lv Guangming Chen | 2020 | npj Flexible Electronics2020，4，1： | 3 |
| 8 | Flexible and biocompatible nanopaper-based electrode arrays for neural activity recording显示文摘 | Yichuan Guo Zhiqiang Fang Mingde Du Long Yang Leihou Shao Xiaorui Zhang Li Li Jidong Shi Jinsong Tao Jinfen Wang Hongbian Li Ying Fang | 2018 | Nano Research2018，11，10： | 3 |
| 9 | A model of suitability evaluation of tourism development for the suburban mining wasteland and its empirical research显示文摘The model of suitability evaluation of tourism development for suburban mining wasteland was established in Fengquan District of Xinxiang City, with measurable methods to provide the basis for its tourism development and landscape planning. The construction and evaluation of the model was conducted with AHP method from the follow-ing four aspects: ecological importance, landscape importance, economic importance and social importance, vali-dated with the case. In the established evaluation system, weight values of six indexes are higher than 0.05, among which the weight of industrial characteristics is the highest, and the weight of area, pollution conditions, air quality conditions, landscape diversity and topography were also higher. There are still seven indicators with weight values of higher than 0.02, including land price, transportation accessibility, geological conditions, water conditions, finan-cial security, distance to cities and similar competition. Weight values of five indexes are lower than 0.02, including government function, vegetation conditions, soil conditions, urban economic level and major tourism environment. We have tried to set a weighting set by AHP to avoid the shortcomings in ordinary weighting process, to perform the tourism evaluation with a maturely-developed method and solve the multi-indicator evaluation problems which in-volve the fuzziness and variability of scaling effectively. Our calculating method is a simple, reasonable, quantitative and feasible one, with general signif icance to non-structuralized project as development of wasteland. | Qiao Lifang Zhang Yichuan Feng Lei | 2008 | Ecological Economy2008，4，3： | 2 |
| 10 | Inhibition of furin by bone targeting superparamagnetic iron oxide nanoparticles alleviated breast cancer bone metastasis显示文摘Breast cancer bone metastasis poses significant challenge for therapeutic strategies.Inside the metastatic environment,osteoclasts and tumor cells interact synergistically to promote cancer progression.In this study,the proprotein convertase furin is targeted due to its critical roles in both tumor cell invasion and osteoclast function.Importantly,the furin inhibitor is specifically delivered by bone targeting superparamagnetic iron oxide(SPIO)nanoparticles.Our in vitro and in vivo data demonstrate that this system can effectively inhibit both osteoclastic bone resorption and breast cancer invastion,leading to alleviated osteolysis.Therefore,the bone targeting&furin inhibition nanoparticle system is a promising therapeutic and diagnostic strategy for breast cancer bone metastasis. | Yichuan Pang Li Su Yao Fu Fan Jia Chenxi Zhang Xiankun Cao Wenxin He Xueqian Kong Jiake Xu Jie Zhao An Qin | 2021 | Bioactive Materials2021，6，3： | 2 |
| 11 | Biomarkers of aging显示文摘Aging biomarkers are a combination of biological parameters to(i)assess age-related changes,(ii)track the physiological aging process,and(iii)predict the transition into a pathological status.Although a broad spectrum of aging biomarkers has been developed,their potential uses and limitations remain poorly characterized.An immediate goal of biomarkers is to help us answer the following three fundamental questions in aging research:How old are we?Why do we get old?And how can we age slower?This review aims to address this need.Here,we summarize our current knowledge of biomarkers developed for cellular,organ,and organismal levels of aging,comprising six pillars:physiological characteristics,medical imaging,histological features,cellular alterations,molecular changes,and secretory factors.To fulfill all these requisites,we propose that aging biomarkers should qualify for being specific,systemic,and clinically relevant. | Aging Biomarker Consortium Hainan Bao Jiani Cao Mengting Chen Min Chen Wei Chen Xiao Chen Yanhao Chen Yu Chen Yutian Chen Zhiyang Chen Jagadish K Chhetri Yingjie Ding Junlin Feng Jun Guo Mengmeng Guo Chuting He Yujuan Jia Haiping Jiang Ying Jing Dingfeng Li Jiaming Li Jingyi Li Qinhao Liang Rui Liang Feng Liu Xiaoqian Liu Zuojun Liu Oscar Junhong Luo Jianwei Lv Jingyi Ma Kehang Mao Jiawei Nie Xinhua Qiao Xinpei Sun Xiaoqiang Tang Jianfang Wang Qiaoran Wang Siyuan Wang Xuan Wang Yaning Wang Yuhan Wang Rimo Wu Kai Xia Fu-Hui Xiao Lingyan Xu Yingying Xu Haoteng Yan Liang Yang Ruici Yang Yuanxin Yang Yilin Ying Le Zhang Weiwei Zhang Wenwan Zhang Xing Zhang Zhuo Zhang Min Zhou Rui Zhou Qingchen Zhu Zhengmao Zhu Feng Cao Zhongwei Cao Piu Chan Chang Chen Guobing Chen Hou-Zao Chen Jun Chen Weimin Ci Bi-Sen Ding Qiurong Ding Feng Gao Jing-Dong JHan Kai Huang Zhenyu Ju Qing-Peng Kong Ji Li Jian Li Xin Li Baohua Liu Feng Liu Lin Liu Qiang Liu Qiang Liu Xingguo Liu Yong Liu Xianghang Luo Shuai Ma Xinran Ma Zhiyong Mao Jing Nie Yaojin Peng Jing Qu Jie Ren Ruibao Ren Moshi Song Zhou Songyang Yi Eve Sun Yu Sun Mei Tian Shusen Wang Si Wang Xia Wang Xiaoning Wang Yan-Jiang Wang Yunfang Wang Catherine CL Wong Andy Peng Xiang Yichuan Xiao Zhengwei Xie Daichao Xu Jing Ye Rui Yue Cuntai Zhang Hongbo Zhang Liang Zhang Weiqi Zhang Yong Zhang Yun-Wu Zhang Zhuohua Zhang Tongbiao Zhao Yuzheng Zhao Dahai Zhu Weiguo Zou Gang Pei Guang-Hui Liu | 2023 | Science China(Life Sciences)2023，66，5： | 2 |
| 12 | Growth asymmetry precedes differential auxin response during apical hook initiation in Arabidopsis显示文摘The development of a hook-like structure at the apical part of the soil-emerging organs has fascinated botanists for centuries,but how it is initiated remains unclear.Here,we demonstrate with highthroughput infrared imaging and 2-D clinostat treatment that,when gravity-induced root bending is absent,apical hook formation still takes place.In such scenarios,hook formation begins with a de novo growth asymmetry at the apical part of a straightly elongating hypocotyl.Remarkably,suchde novo asymmetric growth,but not the following hook enlargement,precedes the establishment of a detectable auxin response asymmetry,and is largely independent of auxin biosynthesis,transport and signaling.Moreover,we found that functional cortical microtubule array is essential for the following enlargement of hook curvature.When microtubule array was disrupted by oryzalin,the polar localization of PIN proteins and the formation of an auxin maximum became impaired at the to-be-hook region.Taken together,we propose a more comprehensive model for apical hook initiation,in which the microtubuledependent polar localization of PINs may mediate the instruction of growth asymmetry that is either stochastically taking place,induced by gravitropic response,or both,to generate a significant auxin gradient that drives the full development of the apical hook. | Yang Peng Dan Zhang Yuping Qiu Zhina Xiao Yusi Ji Wenyang Li Yiji Xia Yichuan Wang Hongwei Guo | 2022 | Journal of Integrative Plant Biology2022，64，1： | 1 |
| 13 | Toward green cloud computing:an attribute clustering based collaborative fileering method for virtual machine migration显示文摘 | Zhang Liumei Ma Jianfeng Wang Yichuan | 2013 | Information Technology Journal2013，12，23： | 1 |
| 14 | Experimental study on the thermal performance of tunnel lining ground heat exchangers显示文摘 | Guozhu Zhang Caichu Xia Yong Yang Meng Sun Yichuan Zou | 2014 | Energy & Buildings2014，，： | 1 |
| 15 | A new model and analytical solution for the heat conduction of tunnel lining ground heat exchangers显示文摘 | Guozhu Zhang Caichu Xia Meng Sun Yichuan Zou Suguang Xiao | 2013 | Cold Regions Science and Technology2013，，： | 1 |
| 16 | An Evaluation Method of Wasteland Landscape Restoration Plan Based on BP Neural Net- work Model显示文摘 | Zhang Yichuan Qiao Lifang Qi Anguo Etc | 2012 | Journal of Food Agriculture & Environmen2012，10，34： | 1 |
| 17 | Polynomial regression interval-valued fuzzy systems显示文摘 | Yu Qiu Hong Yang Yan-Qing Zhang Yichuan Zhao | 2008 | Soft Computing2008，，2： | 1 |
| 18 | An evaluation method of wasteland landscape restoration plan based on BP neural network model显示文摘 | Zhang Yichuan Qiao Lifang Qi Anguo | 2012 | Journal of Food Agriculture & Environment2012，，10： | 1 |
| 19 | Does elevated asymmetrical dimethylarginine predict major adverse cardiac events and mortality in patients after percutaneous coronary intervention?显示文摘 | Yang Shao Yichuan Fan Jun Li Hui Cao Bing Liu Junpeng Wang Jun Yang Qiang Zhang Xinhua Hu | 2014 | International Journal of Cardiology2014，，： | 1 |
| 20 | Towards energy efficient cloud:an optimized ant colony model for virtual machine placement显示文摘A virtual machine placement optimization model based on optimized ant colony algorithm is proposed.The model is able to determine the physical machines suitable for hosting migrated virtual machines.Thus,it solves the problem of redundant power consumption resulting from idle resource waste of physical machines.First,based on the utilization parameters of the virtual machine,idle resources and energy consumption models are proposed.The models are dedicated to quantifying the features of virtual resource utilization and energy consumption of physical machines.Next,a multi-objective optimization strategy is derived for virtual machine placement in cloud environments.Finally,an optimal virtual machines placement scheme is determined based on feature metrics,multi-objective optimization,and the ant colony algorithm.Experimental results indicate that compared with the traditional genetic algorithms-based MGGA model,the convergence rate is increased by 16%,and the optimized highest average energy consumption is reduced by 18%.The model exhibits advantages in terms of algorithm efficiency and efficacy. | ZHANG Liumei WANG Yichuan ZHU Lei JI Wenjiang | 2016 | Journal of Communications and Information Networks2016，1，4： | 1 |
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