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| 1 | MEKK1, MKK1/MKK2 and MPK4 function together in a mitogen-activated protein kinase cascade to regulate innate immunity in plants显示文摘激活 Mitogen 的蛋白质 kinase (MAPK ) 串联在调整植物起重要作用天生的有免疫力的回答。在到为有组成的防卫回答的异种的搜索的一幅基因屏幕,我们识别了展出房间死亡和组成的防卫回答的 mpk4 和 mekk1 的多重等位基因。双分子的荧光互补(BiFC ) 分析证明 MPK4 和 MEKK1 与 MKK1 和 MKK2 交往,二密切相关的 MAPK kinases。mkk1 和 mkk2 单身者异种植物没有明显的变异的显型。测试 MKK1 和 MKK2 是否冗余地工作, mkk1 mkk2 两倍异种被产生。mkk1 mkk2 两倍变异的植物在幼苗舞台和幼苗致命性显型死是温度依赖者。类似于 mpk4 和 mekk1 异种,两倍变异的幼苗积累的 mkk1 mkk2 H2O2 高级,显示自发的房间死亡,联系的组成地快速的致病(PR ) 基因和展览病原体抵抗。另外,由 flg22 的 MPK4 的激活在 mkk1 mkk2 被损害两倍异种,在地图 kinase 串联和 MPK4 和 MEKK1 建议那 MKK1 和 MKK2 功能否定地在植物调整天生的有免疫力的回答。 | Minghui Gao Jinman Liu Dongling Bi Zhibin Zhang Fang Cheng2, Sanfeng Chen Yuelin Zhang | 2008 | Cell Research2008，18，12： | 37 |
| 2 | Genetic diversity of rice cultivars (Oryza sativa L.) in China and the temporal trends in recent fifty years显示文摘To understand geographical distribution of the genetic diversity of rice cultivars {Oryza sativa L.) and its trends in recent fifty years in China, 453 ’ accessions were analyzed by 36 microsatellites loci and 42 phenotypic traits. Results revealed that the genetic diversity by SSRs is highly consistent with that by phenotypic traits and the genetic diversity of indica cultivars was higher than that of japonica cultivars; the genetic diversity of cultivars declined from 1950s to 1980s and then increased greatly; among the six rice ecological zones (REZs), genetic diversity of REZTl was the highest and those of REZV and REZVT were the lowest at both DNA and phenotypic level. Jiangsu and Jiangxi provinces in the middle and lower reaches of Yangtze River and Sichuan province in southwest of China were the areas with the highest genetic diversity. Breeders in REZV which is an important japonica rice area but with very low genetic diversity should explore more gene resources to widen the genetic backgrounds of cultivars. | QI Yonawen ZHANG Dongling ZHANG Hongliang WANG Meixing SUN Junli WEI Xinghua QIU Zongen TANG Shengxiang CAO Yongsheng WANG Xiangkun LI Zichao | 2006 | Chinese Science Bulletin2006，51，6： | 27 |
| 3 | Identification of quantitative trait loci for the dead leaf rate and the seedling dead rate under alkaline stress in rice显示文摘The quantitative trait loci (QTLs) for the dead leaf rate (DLR) and the dead seedling rate (DSR) at the different rice growing periods after transplanting under alkaline stress were identified using an F2:3 population, which included 200 individuals and lines derived from a cross between two japonica rice cultivars Gaochan 106 and Changbai 9 with microsatellite markers. The DLR detected at 20 days to 62 days after transplanting under alkaline stress showed continuous normal or near normal distributions in F3 lines, which was the quantita- tive trait controlled by multiple genes. The DSR showed a continuous distribution with 3 or 4 peaks and was the quantitative trait con- trolled by main and multiple genes when rice was grown for 62 days after transplanting under alkaline stress. Thirteen QTLs associated with DLR were detected at 20 days to 62 days after transplanting under alkaline stress. Among these, qDLR9-2 located in RM5786?RM160 on chromosome 9 was detected at 34 days, 41 days, 48 days, 55 days, and 62 days, respectively; qDLR4 located in RM3524?RM3866 on chromosome 4 was detected at 34 days, 41 days, and 48 days, respectively; qDLR7-1 located in RM3859?RM320 on chromosome 7 was detected at 20 days and 27 days; and qDLR6-2 in RM1340-RM5957 on chromosome 6 was detected at 55 days and 62 days, respectively. The alleles of both qDLR9-2 and qDLR4 were derived from alkaline sensitive parent 'Gaochan106'. The alleles of both qDLR7-1 and qDLR6-2 were from alkaline tolerant parent Changbai 9. These gene actions showed dominance and over dominance primarily. Six QTLs associated with DSR were detected at 62 days after transplanting under alkaline stress. Among these, qDSR6-2 and qDSR8 were located in RM1340?RM5957 on chromosome 6 and in RM3752?RM404 on chromosome 8, respectively, which were asso- ciated with DSR and accounted for 20.32% and 18.86% of the observed phenotypic variation, respectively; qDSR11-2 and qDSR11-3 were located in RM536?RM479 and RM2596?RM286 on chromosome 11, respectively, which were associated with DSR explaining 25.85% and 15.41% of the observed phenotypic variation, respectively. The marker flanking distances of these QTLs were quite far ex- cept that of qDSR6-2, which should be researched further. | Dongling Qi Guizhen Guo Myung-chul Lee Junguo Zhang Guilan Cao Sanyuan Zhang Seok-cheol Suh Qingyang Zhou Longzhi Han | 2008 | Journal of Genetics and Genomics2008，35，5： | 8 |
| 4 | Geographical genetic diversity and divergence of common wild rice (O. rufipogon Griff.) in China显示文摘Using 36 SSR markers and 889 accessions of common wild rice in China, the genetic diversity and the divergence among different geographical populations are investigated. Guangdong Province has the largest number of alleles, which account for 84% of the total alleles detected in the study, followed by Guangxi Province. The Nei's gene diversity indices, from high to low, are in the sequence of Hainan, Guangdong, Guangxi, Fujian, Hunan, Jiangxi, and Yunnan provinces. Two genetic diversity centers of Chinese common wild rice are detected on the basis of geographic analysis, i.e., the region covering Boluo, Zijin, Lufeng, Haifeng, Huidong and Huiyang counties of Guangdong Province and the region covering Yongning, Longan, Laibin and Guigang counties of Guangxi Province. The common wild rice in Yunnan, Hunan, Jiangxi, and Fujian provinces are diverged into respectively independent populations with relatively large genetic distances, whereas, those in Hainan, Guangdong and Guangxi provinces have relatively low genetic divergence. Under the condition of geographic separation, natural selection is considered as one of the primary forces contributing to the divergence of common wild rice in China. | WANG MeiXing ZHANG HongLiang ZHANG DongLing PAN DaJian LI DaoYuan FAN ZhiLan QI YongWen SUN JunLi YANG QingWen LI Chen LI ZiChao | 2008 | Chinese Science Bulletin2008，53，22： | 8 |
| 5 | Assessing indica-japonica differentiation of improved rice varieties using microsatellite markers显示文摘To assess the indica-japonica differentiation of improved rice varieties, a total of 512 modern varieties including 301 indica and 211 japonica accessions were analyzed using 36 microsatellites. The Fst coefficients ranged from 0.002 to 0.730 among the loci with an average of 0.315. Significant differentiation was detected at 94.4% of the loci studied (P<0.05, pairwise Fst tests), indicating that there was a high level of indica-japonica differentiation within the improved varieties. At 18 loci, about 74%-98% of the alleles of indica and japonica accessions were distributed in two ranges of amplicon length. Linkage disequilibrium analysis showed that the distribution trends were significantly nonrandomly associated. Using the differentiation trends at the 18 loci, microsatellite index (MI) was proposed for discrimination of the two subspecies. When rice accessions with MI value greater than zero were classified as indica, and those with MI value smaller than zero were classified as japonica, about 96.1% of the accessions could be classified. This result agrees with the classification based on morphological-physiological characters, indicating that this method is feasible and effective. | Yongwen Qi Hongliang Zhang Dongling Zhang Meixing Wang Junli Sun Li Ding Fenghua Wang Zichao Li | 2009 | Journal of Genetics and Genomics2009，36，5： | 5 |
| 6 | Genetic structure and diversity of Oryza sativa L. in Guizhou,China显示文摘Preserving many kinds of rice resources and rich variations, Guizhou Province is one of the districts with the highest genetic diversity of cultivated rice (Oryza sativa L.) in China. In the current research, genetic diversity and structure of 537 accessions of cultivated rice from Guizhou were studied using 36 microsatellite markers and 39 phenotypic characters. The results showed that the model-based genetic structure was the same as genetic-distance-based one using SSRs but somewhat different from the documented classification (mainly based on phenotype) of two subspecies. The accessions being classified into indica by phenotype but japonica by genetic structure were much more than that being classified into japonica by phenotype but indica by genetic structure. Like Ding Ying’s taxonomic sys- tem of cultivated rice, the subspecific differentiation was the most distinct differentiation within culti- vated rice. But the differentiation within indica or japonica population was different: japonica presented clearer differentiation between soil-watery ecotypes than indica, and indica presented clearer differen- tiation between seasonal ecotypes than japonica. Cultivated rices in Guizhou revealed high genetic diversity at both DNA and phenotypic levels. Possessing the highest genetic diversity and all the nec- essary conditions as a center of genetic diversity, region Southwestern of Guizhou was suggested as the center of genetic diversity of O. sativa L. from Guizhou. | ZHANG DongLing ZHANG HongLiang WEI XingHua QI YongWen WANG Meixing SUN JunLi DING Li TANG ShengXiang QIU Zong'En CAO YongSheng WANG XiangKun LI ZiChao | 2007 | Chinese Science Bulletin2007，52，3： | 5 |
| 7 | Effect of rotationally accelerated shot peening on the microstructure and mechanical behavior of a metastableβtitanium alloy显示文摘Microstructural evolution and deformation mechanism of a metastableβalloy(Ti-10 V-2 Fe-3 Al)processed by rotationally accelerated shot peening(RASP)were systematically investigated with optical microscopy,X-ray diffraction,electron backscatter diffraction and transmission electron microscopy.Different gradient hierarchical microstructures(gradients inα″martensite andβphase,and hierarchical twins range from the nanoscale to microscale)can be fabricated by RASP via changing the shot peening time.The hardening behavior and tensile mechanical properties of gradient hierarchical microstructure were systematically explored.Novel deformation twinning systems of{112}α″and{130}<310>α″in the kinkedα″martensite were revealed during the tensile deformation.It was found that stress-induced martensitic transformation,twinnedα″martensite and the related dynamic grain refinement contribute to hardness and work hardening ability.Simultaneous improvement of strength and ductility of the metastableα″titanium alloy can be achieved by introducing a gradient hierarchical microstructure. | Xinkai Ma Zhuo Chen Dongling Zhong SNLuo Lei Xiao Wenjie Lu Shanglin Zhang | 2021 | Journal of Materials Science & Technology2021，，16： | 4 |
| 8 | Fine mapping of the awn gene on chromosome 4 in rice by association and linkage analyses显示文摘Awnness is a key trait in rice domestication, yet no studies have been conducted on fine mapping or association mapping of the rice awn gene. In this study, we investigated the awnness and genotype of a core collection of 303 cultivated rice varieties and a BC5F2 segregating population of 200 individuals. Combining association and linkage analyses, we mapped the awnness related genes to chromosome 4. Primary association analysis using 24 SSR markers revealed five loci significantly associated with awnness on chromosome 4. The associated markers cover previously identified regions. Fine association mapping was conducted using another 29 markers within a 4-Mb region, covering the associated marker in34, which is close to the awn gene Awn4.1. Seven associated markers were revealed, distributed over an 870-kb region. Combining the fine association mapping and linkage analysis of awnness in the 200 BC5F2 segregating population, we finally identified a 330-kb region as the candidate region for Awn4.1. The results indicate that combining association mapping and linkage mapping provides an efficient and precise approach to both genome-wide mapping and fine mapping of rice genes. | HU GuangLong ZHANG DongLing PAN HuiQiao LI Ben WU JianTao ZHOU XueYa ZHANG QunYuan ZHOU Lei YAO GuoXin LI JunZhou LI JinJie ZHANG HongLiang LI ZiChao | 2011 | Chinese Science Bulletin2011，56，9： | 4 |
| 9 | Bt protein expression in the transgenic insect-resistant cotton in China显示文摘According to statistics of International Service for the Acquisition of Agri-biotech Applications(ISAAA),18million farmers in 28 countries planted more than 181million hectares of genetically modified(GM)crops in2014,at an annual growth rate of between 3%–4%,with6.3 million ha more than 2013[1].Among these counties,China ranks the sixth with 3.9 million ha.Globally,27kinds of transgenic crops have been approved.The four main food groups for which GM varieties are | Guoqing Sun Dongling Zhang Rui Zhang Yuan Wang Zhigang Meng Tao Zhou Chenzhen Liang Tao Zhu Sandui Guo | 2016 | Science Bulletin2016，61，20： | 3 |
| 10 | Genetic structure and eco-geographical differentiation of cultivated Hsien rice(Oryza sativa L.subsp.indica) in China revealed by microsatellites显示文摘Indica is not only an important rice subspecies widely planted in Asia and the rest of the world,but it is also the genetic background of the majority of hybrid varieties in China.Studies on genetic structure and genetic diversity in indica germplasm resources are important for the classification and utilization of cultivated rice in China.Using a genetically representative core collection comprising 1482 Chinese indica landraces,we analysed the genetic structure,geographic differentiation and diversity.Model-based structure analysis of varieties within three ecotypes revealed nine eco-geographical types partially accordant with certain ecological zones in China.Differentiation of eco-geographical types was attributed to local ecological adaption and physical isolation.These groups may be useful for developing heterotic groups of indica.To facilitate the identification of different ecotypes and eco-geographical types,we identified characteristic SSR alleles of each ecotype and eco-geographical type and a rapid index of discrimination based on characteristic alleles.The characteristic alleles and rapid discrimination index may guide development of heterotic groups,and selection of hybrid parents. | ZHANG DongLing ZHANG HongLiang QI YongWen WANG MeiXing SUN JunLi DING Li LI ZiChao | 2013 | Chinese Science Bulletin2013，58，3： | 3 |
| 11 | Wave packet solutions in a bounded equatorial ocean and its interannual and decadal variabilities显示文摘Linearized shallow water perturbation equations with approximation in an equatorial β plane are used to obtain the analytical solution of wave packet anomalies in the upper bounded equatorial ocean. The main results are as follows. The wave packet is a superposition of eastward travelling Kelvin waves and westward travelling Rossby waves with the slowest speed, and satisfies the boundary conditions of eastern and western coasts, respectively.The decay coefficient of this solution to the north and south sides of the equator is inversely proportional only to the phase velocity of Kelvin waves in the upper water. The oscillation frequency of the wave packet, which is also the natural frequency of the ocean, is proportional to its mode number and the phase velocity of Kelvin waves and is inversely proportional to the length of the equatorial ocean in the east-west direction. The flow anomalies of the wave packet of Mode 1 most of the time appear as zonal flows with the same direction. They reach the maximum at the center of the equatorial ocean and decay rapidly away from the equator, manifested as equatorially trapped waves. The flow anomalies of the wave packet of Mode 2 appear as the zonal flows with the same direction most of the time in half of the ocean, and are always 0 at the center of the entire ocean which indicates stagnation, while decaying away from the equator with the same speed as that of Mode 1. The spatial structure and oscillation period of the wave packet solution of Mode 1 and Mode 2 are consistent with the changing periods of the surface spatial field and time coefficient of the first and second modes of complex empirical orthogonal function(EOF)analysis of flow anomalies in the actual equatorial ocean. This indicates that the solution does exist in the real ocean, and that El Ni?o-Southern Oscillation(ENSO) and Indian Ocean dipole(IOD) are both related to Mode 2.After considering the Indonesian throughflow, we can obtain the length of bounded equatorial ocean by taking the sum of that of the tropical Indian Ocean and the tropical Pacific Ocean, thus this wave packet can also explain the decadal variability(about 20 a) of the equatorial Pacific and Indian Oceans. | Dongling Zhang Juan Zhu Xu Lu Ming Zhang | 2019 | Acta Oceanologica Sinica2019，38，3： | 2 |
| 12 | Product design on the basis of fuzzy quality function deployment显示文摘In the implementation of quality function deployment (QFD),the determination of the target values of engineering characteristics is a complex decision process with multiple variables and multiple objectives that should trade off,and optimize all kinds of conflicts and constraints.A fuzzy linear programming model (FLP) is proposed.On the basis of the inherent fuzziness of QFD system,triangular fuzzy numbers are used to represent all the relationships and correlations,and then,the functional relationships between the customer needs and engineer- ing characteristics and the functional correlations among the engineering characteristics are determined with the information in the house of quality (HoQ) fully used.The fuzzy linear programming (FLP) model aims to find the optimal target values of the engineering characteristics to maximize the customer satisfaction.Finally,the proposed method is illustrated by a numerical example. | Li Zhaoling Gao Qisheng Zhang Dongling | 2008 | Journal of Systems Engineering and Electronics2008，19，6： | 2 |
| 13 | Enterprise WeChat Groups: Their Effect on Work-Life Conflict and Life-Work Enhancement显示文摘社会媒介技术为要连接工作的雇员使它逐渐地可行。WeChat,一个最新新兴的社会媒介平台,广泛地在日常生活被使用,还几乎仍然没有在企业的 WeChat 组的使用的后果的小理解。基于边界理论,我们建议在企业的 WeChat 组的使用为雇员有两利弊。我们从 202 个雇员的联机调查收集了数据。在企业 WeChat 张贴工作相关的内容组织的结果表演为雇员在工作上有有益的影响而且引起了工作生活冲突(WLC ) 。然而,在企业 WeChat 组张贴生活相关的内容贡献雇员一生的工作改进(LWE ) 。贡献和这些调查结果的未来学习方向被讨论。 | Shengming Liu Ye Zhang Lifan Chen Li Guo Dongling Yu | 2015 | Frontiers of Business Research in China2015，9，4： | 2 |
| 14 | Transcriptome Profiling of the Abdominal Skin of Larimichthys crocea in Light Stress显示文摘Large yellow croaker(Larimichthys crocea), one of the most important marine fish species in China, can change its abdominal skin color when it is shifted from light to dark or from dark to light, providing us an opportunity of investigating the molecular responding mechanism of teleost in light stress. The gene expression profile of fish under light stress is rarely documented. In this research, the transcriptome profiles of the abdominal skin of L. crocea exposed to light or dark for 0 h, 0.5 h and 2 h were produced by next-generation sequencing(NGS). The cluster results demonstrated that stress period, rather than light intensity(e.g., light or dark), is the major influencing factor. Differently expressed genes(DEGs) were identified between 0 h and 0.5 h groups, between 0 h and 2 h groups, between 0.5 h light and 0.5 h dark, and between 2 h light and 2 h dark, respectively. The gene ontology(GO) and Kyoto Encyclopedia of Genes and Genomes(KEGG) annotation revealed that the genes relating to immunity, energy metabolism, and cytoskeletal protein binding were significantly enriched. The detailed analysis of transcriptome profiles also revealed regular gene expression trends, indicating that the elaborate gene regulation networks underlined the molecular responses of the fish to light stress. This transcriptome analysis suggested that systematic and complicated regulatory cascades were functionally activated in response to external stress, and coloration change caused by light stress was mainly attributed to the change in the density of chromatophores for L. crocea. This study also provided valuable information for skin coloration or light stress research on other marine fish species. | HAN Zhaofang LV Changhuan XIAO Shijun YE Kun ZHANG Dongling TSAI Huai Jen WANG Zhiyong | 2018 | Journal of Ocean University of China2018，17，2： | 2 |
| 15 | Dynamical framework with blocking topography coordinates for atmospheric GCM and its validation显示文摘The dynamical framework with Blocking To-pography Coordinates (hereafter, BTC), which is suited tohandle the steep topography for the atmospheric generalcirculation models, is presented in this paper, together withits validation results. The integral properties of both the dif-ferential and finite-difference equations for the BTC dy-namical core are: gross mass conservation, quadratic con-servation for advection terms, Coriolis force does not changethe kinetic energy, conservation of total available energy. Theimproved nonlinear iteration scheme is utilized for thetime-integration. The energy conservation for BTC dynami-cal core is validated by using the integration results from9-layer and 21-layer version respectively. Comparison resultsshow that, the changes of the kinetic energy and total avail-able potential energy during the integration are quite closefor both the BTC dynamical framework and the dynamicalframework of IAP 9-level and IAP 21-level AGCM, and thismay suggest that the BTC dynamical core can be used forlong-term integration with good computational stability.Furthermore, the BTC dynamical core has the advantageover the terrain following (sigma) coordinates in its betterrepresentation of the influence of the large-scale topographyon the atmospheric general circulation. Finally, the correct-ness and reasonableness of the BTC dynamical core has beenfurther proved by the numerical simulation of the topogra-phy influence on the quasi-stationary planetary wave with21-layer version of BTC dynamical framework. | LIN Zhaohui~1, ZHANG Ming~(1,2), LIANG Danqing~(1,2) WANG Aihui~1, ZHANG Dongling~1 & ZENG Qingcun~1 1. ICCES, Institute of Atmospheric Physics, Chinese Academy of Sciences. Beijing 100029. China 2. College of Meteorology. PLA University of Science and Technology, Nanjing 211101. China | 2003 | Chinese Science Bulletin2003，48，S2： | 2 |
| 16 | The role of calcium, P38 MAPK in dihydroartemisinin-induced apoptosis of lung cancer PC-14 cells显示文摘 | Deguang Mu Wei Zhang Dongling Chu Tonggang Liu Yonghong Xie Enqing Fu Faguang Jin | 2008 | Cancer Chemotherapy and Pharmacology2008，，4： | 1 |
| 17 | Therapeutic potential of C1632 by inhibition of SARS-CoV-2 replication and viral-induced inflammation through upregulating let-7显示文摘Dear Editor,The COVID-19 pandemic caused by SARS-CoV-2 has led to acute respiratory distress syndrome(ARDS)with a high rate of death.An excessive inflammatory response,caused by virus infection,is associated with severe clinical manifestations that may lead to death of patients.1 Therefore,the blockage of virus replication and suppression of hyper-inflammatory response are beneficial for COVID-19 treatment.However,the drug targeting both virus and hyper-inflammation,as far as we know,is not available yet. | Chen Xie Yanlian Chen Dongling Luo Zhen Zhuang Heping Jin Haoxian Zhou Xiaocui Li Haijun Lin Xiaohui Zheng Jing Zhang Peihui Wang Jincun Zhao Yong Zhao Hui Huang | 2021 | Signal Transduction and Targeted Therapy2021，6，3： | 1 |
| 18 | Microstructure Evolution and Mechanical Properties of T15 High Speed Steel Prepared by Twin-atomiser Spray Forming and Thermo-mechanical Processing显示文摘 | Zhang Guoqing Yuan Hua Jiao Dongling | 2012 | Materials Science & Engineering 42012，558，15： | 1 |
| 19 | Decomposing phenol by the hidden talent of ferromagnetic nanoparticles显示文摘 | Jinbin Zhang Jie Zhuang Lizeng Gao Yu Zhang Ning Gu Jing Feng Dongling Yang Jingdong Zhu Xiyun Yan | 2008 | Chemosphere2008，，9： | 1 |
| 20 | Avian detection and monitoring using frequency-stepped chirp signal radar 显示文摘 | ZHANG Qun LUO Ying HU Dongling | 2008 | Progress in Electromagnetics Research Symposium Online2008，4，1： | 1 |
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