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| 1 | Terrestrial carbon sinks in China and around the world and their contribution to carbon neutrality显示文摘Enhancing the terrestrial ecosystem carbon sink(referred to as terrestrial C sink) is an important way to slow down the continuous increase in atmospheric carbon dioxide(CO_(2)) concentration and to achieve carbon neutrality target.To better understand the characteristics of terrestrial C sinks and their contribution to carbon neutrality,this review summarizes major progress in terrestrial C budget researches during the past decades,clarifies spatial patterns and drivers of terrestrial C sources and sinks in China and around the world,and examines the role of terrestrial C sinks in achieving carbon neutrality target.According to recent studies,the global terrestrial C sink has been increasing from a source of (-0.2±0.9) Pg C yr^(-1)(1 Pg=1015g)in the 1960s to a sink of (1.9±1.1) Pg C yr^(-1) in the 2010s.By synthesizing the published data,we estimate terrestrial C sink of 0.20–0.25 Pg C yr^(-1) in China during the past decades,and predict it to be 0.15–0.52 Pg C yr^(-1) by 2060.The terrestrial C sinks are mainly located in the mid-and high latitudes of the Northern Hemisphere,while tropical regions act as a weak C sink or source.The C balance differs much among ecosystem types:forest is the major C sink;shrubland,wetland and farmland soil act as C sinks;and whether the grassland functions as C sink or source remains unclear.Desert might be a C sink,but the magnitude and the associated mechanisms are still controversial.Elevated atmospheric CO_(2) concentration,nitrogen deposition,climate change,and land cover change are the main drivers of terrestrial C sinks,while other factors such as fires and aerosols would also affect ecosystem C balance.The driving factors of terrestrial C sink differ among regions.Elevated CO_(2) concentration and climate change are major drivers of the C sinks in North America and Europe,while afforestation and ecological restoration are additionally important forcing factors of terrestrial C sinks in China.For future studies,we recommend the necessity for intensive and long-term ecosystem C monitoring over broad geographic scale to improve terrestrial biosphere models for accurately evaluating terrestrial C budget and its dynamics under various climate change and policy scenarios. | Yuanhe Yang Yue Shi Wenjuan Sun Jinfeng Chang Jianxiao Zhu Leiyi Chen Xin Wang Yanpei Guo Hongtu Zhang Lingfei Yu Shuqing Zhao Kang Xu Jiangling Zhu Haihua Shen Yuanyuan Wang Yunfeng Peng Xia Zhao Xiangping Wang Huifeng Hu Shiping Chen Mei Huang Xuefa Wen Shaopeng Wang Biao Zhu Shuli Niu Zhiyao Tang Lingli Liu Jingyun Fang | 2022 | Science China(Life Sciences)2022，65，5： | 32 |
| 2 | Chinese Trauma Surgeon Association for management guidelines of vacuum sealing drainage application in abdominal surgeries-Update and systematic review显示文摘Vacuum sealing drainage (VSD) is frequently used in abdominal surgeries. However, relevant guidelines are rare. Chin ese Trauma Surge on Associati on orga nized a committee composed of 28 experts across China in July 2017, aiming to provide an evidence-based recommendation for the application of VSD in abdominal surgeries.Eleven questions regarding the use of VSD in abdominal surgeries were addressed:(1) which type of materials should be respectively chosen for the intraperitoneal cavity, retroperitoneal cavity and superficial incisions?(2) Can VSD be preventively used for a high-risk abdominal incision w让h primary suture?(3) Can VSD be used in severely contaminated/infected abdominal surgical sites?(4) Can VSD be used for temporary abdominal cavity closure under some special conditions such as severe abdominal trauma, infection, liver transplantation and intra-abdominal volume increment in abdominal compartment syndrome?(5) Can VSD be used in abdominal organ inflammation, injury, or postoperative drainage?(6) Can VSD be used in the treatment of intestinal fistula and pancreatic fistula?(7) Can VSD be used in the treatment of intra-abdominal and extra-peritoneal abscess?(8) Can VSD be used in the treatment of abdominal wall wounds, wound cavity, and defects?(9) Does VSD in crease the risk of bleeding?(10) Does VSD increase the risk of intestinal wail injury?(11) Does VSD increase the risk of peritoneal adhesion? Focusing on these questions, evidence-based recommendations were given accordingly. VSD was strongly recommended regarding the questions 2-4. Weak recommendations were made regarding questions 1 and 5-11. Proper use of VSD in abdominal surgeries can lower the risk of infection in abdominal incisions with primary suture, treat severely contaminated/infected surgical sites and facilitate temporary abdominal cavity closure. | Yang Li Pei-Yuan Li Shi-Jing Sun Yuan-Zhang Yao Zhan-Fei Li Tao Liu Fan Yang Lian-Yang Zhang Xiang-Jun Bai Jing-Shan Huo Wu-Bing He Jun Ouyang Lei Peng Ping Hu Yan-An Zhu Ping Jin Qi-Feng Shao Yan-Feng Wang Rui-Wu Dai Pei-Yang Hu Hai-Ming Chen Ge-Fei Wang Yong-Gao Wang Hong-Xu Jin Chang-Ju Zhu Qi-Yong Zhang Biao Shao Xi-Guang Sang Chang-Lin Yin | 2019 | Chinese Journal of Traumatology2019，22，1： | 26 |
| 3 | Vegetation Cover Variation in the Qilian Mountains and its Response to Climate Change in 2000-2011显示文摘An understanding of variations in vegetation cover in response to climate change is critical for predicting and managing future terrestrial ecosystem dynamics. Because scientists anticipate that mountain ecosystems will be more sensitive to future climate change compared to others, our objectives were to investigate the impacts of climate change on variation in vegetation cover in the Qilian Mountains(QLM), China, between 2000 and 2011. To accomplish this, we used linear regression techniques on 250-m MODIS Normalized Difference Vegetation Index(NDVI) datasets and meteorological records to determine spatiotemporal variability in vegetation cover and climatic factors(i.e. temperature and precipitation). Our results showed that temperatures and precipitation have increased in this region during our study period. In addition, we found that growing season mean NDVI was mainly distributed in the vertical zone from 2,700 m to 3,600 m in elevation. In the study region, we observed significant positive and negative trends in vegetation cover in 26.71% and2.27% of the vegetated areas. Correlation analyses indicated that rising precipitation from May to August was responsible for increased vegetation cover in areas with positive trends in growing season mean NDVI. However, there was no similar significant correlation between growing season mean NDVI and precipitation in regions where vegetation cover declined throughout our study period. Using spatialstatistics, we found that vegetation cover frequently declined in areas within the 2,500–3,100 m vertical zone, where it has steep slope, and is on the sunny side of mountains. Here, the positive influences of increasing precipitation could not offset the drier conditions that occurred through warming trends. In contrast, in higher elevation zones(3,900–4,500 m)on the shaded side of the mountains, rising temperatures and increasing precipitation improved conditions for vegetation growth. Increased precipitation also facilitated vegetation growth in areas experiencing warming trends at lower elevations(2,000–2,400 m) and on lower slopes where water was more easily conserved. We suggest that spatial differences in variation in vegetation as the result of climate change depend on local moisture and thermal conditions, which are mainly controlled by topography(e.g. elevation, aspect, and slope), and other factors, such as local hydrology. | DENG Shao-fu YANG Tai-bao ZENG Biao ZHU Xi-fen XU Hao-jie | 2013 | Journal of Mountain Science2013，10，6： | 19 |
| 4 | Carbon budgets of three temperate forest ecosystems in Dongling Mt.,Beijing,China显示文摘There is a general agreement that forest ecosystems in the Northern Hemisphere function as signifi-cant sinks for atmospheric CO2; however, their magnitude and distribution remain large uncertainties. In this paper, we report the carbon (C) stock and its change of vegetation, forest floor detritus, and mineral soil, annual net biomass increment and litterfall production, and respiration of vegetation and soils between 1992 to 1994, for three temperate forest ecosystems, birch (Betula platyphylla) forest, oak (Quercus liaotungensis) forest and pine (Pinus tabulaeformis) plantation in Mt. Dongling, Beijing, China. We then evaluate the C budgets of these forest ecosystems. Our results indicated that total C density (organic C per hectare) of these forests ranged from 250 to 300 t C ha-1, of which 35―54 t C ha-1 from vegetation biomass C and 209―244 t C ha-1 from soil organic C (1 m depth, including forest floor detritus). Biomass C of all three forests showed a net increase, with 1.33―3.55 t C ha-1 a-1 during the study period. Litterfall production, vegetation autotrophic respiration, and soil heterotrophic respira-tion were estimated at 1.63―2.34, 2.19―6.93, and 1.81―3.49 t C ha-1 a-1, respectively. Ecosystem gross primary production fluctuated between 5.39 and 12.82 t C ha-1 a-1, about half of which (46%―59%, 3.20―5.89 t C ha-1 a-1) was converted to net primary production. Our results suggested that pine forest fixed C of 4.08 t ha-1 a-1, whereas secondary forests (birch and oak forest) were nearly in balance in CO2 exchange between the atmosphere and ecosystems. | FANG JingYun LIU GuoHua ZHU Biao WANG XiaoKe LIU ShaoHui | 2007 | Science China Earth Sciences2007，50，1： | 17 |
| 5 | ZmMs30 Encoding a Novel GDSL Lipase Is Essential for Male Fertility and Valuable for Hybrid Breeding in Maize显示文摘Genic male sterility (GMS) is very useful for hybrid vigor utilization and hybrid seed production. Although a large number of GMS genes have been identified in plants, little is known about the roles of GDSL lipase members in anther and pollen development. Here, we report a maize GMS gene, ZmMs30, which encodes a novel type of GDSL lipase with diverged catalytic residues. Enzyme kinetics and activity assays show that ZmMs30 has lipase activity and prefers to substrates with a short carbon chain. ZmMs30 is specifically expressed in maize anthers during stages 7-9. Loss of ZmMs30 function resulted in defective anther cuticle, irregular foot layer of pollen exine, and complete male sterility. Cytological and lipidomics analyses demonstrate that ZmMs30 is crucial for the aliphatic metabolic pathway required for pollen exine formation and anther cuticle development. Furthermore, we found that male sterility caused by loss of ZmMs30 function was stable in various inbred lines with different genetic background, and that it didn't show any negative effect on maize heterosis and production, suggesting that ZmMs30 is valuable for crossbreeding and hybrid seed production. We then developed a new multi-control sterility system using ZmMs30 and its mutant line, and demonstrated it is feasible for generating desirable GMS lines and valu. able for hybrid maize seed production. Taken together, our study sheds new light on the mechanisms of anther and pollen development, and provides a valuable male-sterility system for hybrid breeding maize. | Xueli An Zhenying Dong Youhui Tian Ke Xie Suowei Wu Taotao Zhu Danfeng Zhang Van Zhou Canfang Niu Biao Ma Quancan Hou Jianxi Bao Simiao Zhang Ziwen Li Yanbo Wang Tingwei Yan Xiaojing Sun Yuwen Zhang Jinping Li Xiangyuan Wan | 2019 | Molecular Plant2019，12，3： | 15 |
| 6 | Simultaneous detection of different serum pepsinogens and its primary application显示文摘AIM: To develop the simple, rapid and sensitive dual-label time-resolved fluoroimmunoassay for pepsinogens in human serum.METHODS: Based on two-site sandwich protocol, mono-clonal antibodies (McAbs) against pepsinogen Ⅰ (PG Ⅰ) and PG Ⅱ were co-coated in 96 microtitration wells, and tracer McAbs against PG Ⅰ and PG Ⅱ were labeled with europium (Eu) and samarium (Sm) chelate, respectively. Diluted serum samples of Eu3+- and Sm3+-McAbs were added into microtitration wells simultaneously. After washing, fluorescence of bound Sm3+ and Eu3+ tracers was detected. RESULTS: The detection limit was 0.2 μg/L for PG Ⅰ and 0.05 μg/L for PG Ⅱ. The assay range was 5.0-320.0 μg/Lfor PG Ⅰ and 1.0-55.0 μg/L for PG Ⅱ. The average re-covery rate was 102.7% for PG Ⅰ and 98.8% for PG Ⅱ. Sera from healthy controls and patients with gastric dis-ease were analyzed. The PG detected by dual-label as-say was in good agreement with that detected by single-label assay or by enzyme-linked immunosorbent assay. CONCLUSION: Dual-label assay can provide high-throughput serological screening for gastric diseases. | Zhang, Jue Guo, Ji-Zhong Xiao, Hua-Long Zhu, Lan Liu, Hai-Yan Zhang, Yi Huang, Biao | 2010 | World Journal of Gastroenterology2010，16，24： | 15 |
| 7 | The effects of simulated nitrogen deposition on extracellular enzyme activities of litter and soil among different-aged stands of larch显示文摘Aims Nitrogen(N)addition could affect the rate of forest litter and soil organic matter decomposition by regulating extracellular enzyme activity(EEa).The impact of N addition on EEa may differ across different age stands with different organic matter quality.We were interested in whether the impact of N addition on EEa in litter and mineral soil during the growing season was dependent on stand age of a larch plantation in North China.Methods We added three levels of N(0,20 and 50 kg N ha^(−1) year^(−1))in three age stands(11,20 and 45 years old)of Larix principis-rupprech-tii plantation in North China.We measured potential activities of β-1,4-glucosidase(b),cellobiohydrolase(Cb),β-1,4-N-acetyl-glucosaminidase(Nag)and phenol oxidase(Po)in litter(organic horizon)and mineral soil(0-10 cm)during the second growing sea-son after N amendment.We also measured C and N concentrations,microbial biomass C and N,and KCl-extractable ammonium and nitrate in both litter and mineral soil.Important Findings We observed unimodal patterns of EEa during the growing season in all three stands,consistent with the seasonal variations of soil temperature.stand age had a strong effect on EEa in both litter and mineral soil,and this effect differed between litter and mineral soil as well as between different enzymes.N addition did not significantly affect the activities of b or Cb but significantly suppressed the activity of Nag in litter.We also found stand age-specific responses of Po activity to N addition in both litter and mineral soil.N addition suppressed Po activity of the high C:N ratio litters in 20-and 45-year-old stands but had no significant effect on Po activity of the low C:N ratio litter in 11-year-old stand.moreover,N addition inhibited Po activity of the high C:N ratio soil in 20-year-old stand but had no significant impact on Po activity of the low C:N ratio soils in 11-and 45-year-old stands.overall,stand age had a greater effect on EEa in litter and mineral soil compared to 2 years of N addition.moreover,the effect of N addition on Po activity is stand age dependent,which may affect the long-term soil carbon storage in this forest. | Yuecun Ma Biao Zhu Zhenzhong Sun Chuang Zhao Yan Yang Shilong Piao | 2014 | Journal of Plant Ecology2014，7，3： | 14 |
| 8 | Dynamics of saltwater intrusion in the Modaomen Waterway of the Pearl River Estuary显示文摘Observations indicate an abnormal characteristic of saltwater intrusion in the upper Modaomen Waterway of the Pearl River Estuary,i.e.,the maximum salinity occurs during the neap tide or the coming moderate tide instead of during the spring tide.To explore the associated dynamic mechanisms,a high resolution three-dimensional numerical model was set up based on the Finite Volume Coastal Ocean Model(FVCOM),which covered the entire river network,the Pearl River Estuary,and the adjacent sea.Numerical experiments illustrated that the upper Modaomen Waterway is significantly influenced by the saltwater intrusion from the Hongwan Waterway,a narrow and shallow channel connecting the Modaomen Waterway to the sea.Specific topography,spring-neap tidal variation,local wind stress,and their interaction drive an up-estuary residual current in the Hongwan Waterway,which is much stronger during the neap tide than during the spring tide.As a result,more saltwater in the Hongwan Waterway is spilled over into the Modaomen Waterway during the neap tide or the coming moderate tide.This is the inherent dynamic mechanism why the saltwater intrusion in the upper Modaomen Waterway reaches its maximum during the neap tide or the coming moderate tide.Besides,we also found that the winter prevailing wind can pronouncedly enhance the saltwater intrusion in the Modaomen Waterway. | WANG Biao ZHU JianRong WU Hui YU FuJiang SONG XueJia | 2012 | Science China Earth Sciences2012，55，11： | 12 |
| 9 | Correlation of the occurrence of YMDD mutations with HBV genotypes,HBV-DNA levels,and HBeAg status in Chinese patients with chronic hepatitis B during lamivudine treatment显示文摘BACKGROUND:Continuous lamivudine therapy is associated with high rates of YMDD mutations,which are the main causes of drug resistance.The current study explores the association of the emergence of YMDD mutations with pretherapy HBV genotype,HBV-DNA levels,HBeAg status,and serum alanine aminotransferase(ALT) levels in Chinese patients receiving lamivudine therapy for chronic hepatitis B.METHODS:A total of 319 chronic hepatitis B patients who received lamivudine therapy for more than a year were enrolled in this study.YMDD mutations,HBV genotype,HBV-DNA levels,HBeAg status,and ALT levels were determined prior to their lamivudine treatment and every three months for a year of this therapy.RESULTS:Among the 319 patients,137(42.95%) were infected with genotype B and 182(57.05%) with genotype C.Up to 94 patients(29.47%) developed YMDD mutations within one year of lamivudine therapy.Furthermore,50 patients with HBV genotype B and 44 patients with genotype C developed YMDD mutations(36.50% vs 24.18%,P<0.05).Logistic regression analysis showed that pretherapy HBV genotype,HBV-DNA levels,and HBeAg status are independent factors for the emergence of YMDD mutations(HBV genotype:OR=2.159,95% CI 1.291-3.609,P=0.003;HBV-DNA:OR=1.653,95% CI 1.231-2.218,P=0.001;HBeAg:OR=2.021,95% CI 1.201-3.399,P=0.008).CONCLUSIONS:HBV genotype,HBV-DNA levels,and HBeAg status at baseline are the independent factors associated with the emergence of YMDD mutations among Chinese patients receiving lamivudine therapy for chronic hepatitis B.These findings are helpful to the development of therapeutic strategies for these patients. | Feng Wu,Min-Jin Wu,Xiao-Lin Zhuge,Shao-Ming Zhu and Biao Zhu Department of Chinese Pharmacy, Department of Laboratory Medicine , State Key Laboratory for Diagnosis and Treatment of Infectious Diseases , First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou 310003, China | 2012 | Hepatobiliary & Pancreatic Diseases International2012，11，2： | 11 |
| 10 | Relationship between high-sensitivity C-reactive protein level and angiographical characteristics of coronary atherosclerosis显示文摘 | JIA En-zhi YANG Zhi-jian YUAN Biao ZANG Xiao-ling WANG Rong-hu ZHU Tie-bing WANG Lian-sheng CHEN Bo CAO Ke-jiang HUANG Jun MA Wen-zhu | 2006 | Chinese Medical Journal2006，，4： | 11 |
| 11 | Synthesis of the Diverse Glycosides in Traditional Chinese Medicine显示文摘繁体中文药(TCM ) 是为现代药品的发现和发展的一件巨大的财富藏品。确实,众多的生物学上并且 pharmacologically 重要的分子从 TCM 被识别了;在他们之中,可观的部分属于 glycosides。这些 glycosides 在结构是极其多样的,由 aglycones, glycans,以及 glycosidic 连接的一个大变化组成。另外,这些 glycosides 在自然来源作为同种的物的复杂混合物经常发生。这 microheterogeneity 在可估计的数量导致同类的 glycoside 的隔离一项可怕的任务。因此,向这些自然 glycosides 的合成途径的开发收到了大注意。在这篇报道,我们总结我们在这个话题上花的 twentyyear 努力。55 代表性的 TCMrelevant glycosides 由我们的组综合了被加亮。基于 aglycone 结构,这些 glycosides 被分成三个组,即,类固醇 glycosides 和酉分的 glycosides。典型合成途径被讨论,显示出为 regio 和 glycans 和保护组的全面操作的 stereocontrolled 安装的费力的战术。这些有用、可伸缩的合成途径提供了实际选择给这些 TCM 部件并且这样的可接近性机会为他们的在里面生物的深度和药理学学习。 | Dapeng Zhu Biao Yu | 2018 | Chinese Journal of Chemistry2018，36，8： | 11 |
| 12 | Efficacy and safety of the long-acting fusion inhibitor albuvirtide in antiretroviral-experienced adults with human immunodeficiency virus-1:interim analysis of the randomized,controlled,phase 3,non-inferiority TALENT study显示文摘Background:Albuvirtide is a once-weekly injectable human immunodeficiency virus(HIV)-1 fusion inhibitor.We present interim data for a phase 3 trial assessing the safety and efficacy of albuvirtide plus lopinavir-ritonavir in HIV-1-infected adults already treated with antiretroviral drugs.Methods:We carried out a 48-week,randomized,controlled,open-label non-inferiority trial at 12 sites in China.Adults on the World Health Organization(WHO)-recommended first-line treatment for>6 months with a plasma viral load>1000 copies/mL were enrolled and randomly assigned(1:1)to receive albuvirtide(once weekly)plus ritonavir-boosted lopinavir(ABT group)or the WHO-recommended second-line treatment(NRTI group).The primary endpoint was the proportion of patients with a plasma viral load below 50 copies/mL at 48 weeks.Non-inferiority was prespecified with a margin of 12%.Results:At the time of analysis,week 24 data were available for 83 and 92 patients,and week 48 data were available for 46 and 50 patients in the albuvirtide and NRTI groups,respectively.At 48 weeks,80.4%of patients in the ABT group and 66.0%of those in the NRTI group had HIV-1 RNA levels below 50 copies/mL,meeting the criteria for non-inferiority.For the per-protocol population,the superiority of albuvirtide over NRTI was demonstrated.The frequency of grade 3 to 4 adverse events was similar in the two groups;the most common adverse events were diarrhea,upper respiratory tract infections,and grade 3 to 4 increases in triglyceride concentration.Renal function was significantly more impaired at 12 weeks in the patients of the NRTI group who received tenofovir disoproxil fumarate than in those of the ABT group.Conclusions:The TALENT study is the first phase 3 trial of an injectable long-acting HIV drug.This interim analysis indicates that once-weekly albuvirtide in combination with ritonavir-boosted lopinavir is well tolerated and non-inferior to the WHO-recommended second-line regimen in patients with first-line treatment failure.Trial registration:ClinicalTrials.gov Identifier:NCT02369965;https://www.clinicaltrials.gov.Chinese Clinical Trial Registry No.ChiCTR-TRC-14004276;http://www.chictr.org.cn/enindex.aspx. | Bin Su Cheng Yao Qing-Xia Zhao Wei-Ping Cai Min Wang Hong-Zhou Lu Yuan-Yuan Chen Li Liu Hui Wang Yun He Yu-Huang Zheng Ling-Hua Li Jin-Feng Chen Jian-Hua Yu Biao Zhu Min Zhao Yong-Tao Sun Wen-Hui Lun Wei Xia Li-Jun Sun Li-Li Dai Tai-Yi Jiang Mei-Xia Wang Qing-Shan Zheng Hai-Yan Peng Yao Wang Rong-Jian Lu Jian-Hua Hu Hui Xing Yi-Ming Shao Dong Xie Tong Zhang Fu-Jie Zhang Hao Wu TALENT Study Team | 2020 | Chinese Medical Journal2020，，24： | 10 |
| 13 | Low Root Zone Temperature Exacerbates the Ion Imbalance and Photosynthesis Inhibition and Induces Antioxidant Responses in Tomato Plants Under Salinity显示文摘The combined effects of salinity with low root zone temperature(RZT) on plant growth and photosynthesis were studied in tomato(Solanum lycopersicum) plants.The plants were exposed to two different root zone temperatures(28/20 C,12/8 C,day/night temperature) in combination with two NaCl levels(0 and 100 mmol L-1).After 2 wk of treatment,K+and Na+concentration,leaf photosynthetic gas exchange,chlorophyll fluorescence and leaf antioxidant enzyme activities were measured.Salinity significantly decreased plant biomass,net photosynthesis rate,actual quantum yield of photosynthesis and concentration of K+,but remarkably increased the concentration of Na+.These effects were more pronounced when the salinity treatments were combined with the treatment of low RZT conditions.Either salinity or low RZT individually did not affect maximal efficiency of PSII photochemistry(Fv/Fm),while a combination of these two stresses decreased Fv/Fm considerably,indicating that the photo-damage occurred under such conditions.Non-photochemical quenching was increased by salt stress in accompany with the enhancement of the de-epoxidation state of the xanthophyll cycle,in contrast,this was not the case with low RZT applied individually.Salinity stress individually increased the activities of SOD,APX,GPOD and GR,and decreased the activities of DHAR.Due to the interactive effects of salinity with low RZT,these five enzyme activities increased sharply in the combined stressed plants.These results indicate that low RZT exacerbates the ion imbalance,PSII damage and photosynthesis inhibition in tomato plants under salinity.In response to the oxidative stress under salinity in combination with low RZT,the activities of antioxidant enzymes SOD,APX,GPOD,DHAR and GR were clearly enhanced in tomato plants. | HE Yong YANG Jing ZHU Biao ZHU Zhu-jun | 2014 | Journal of Integrative Agriculture2014，13，1： | 9 |
| 14 | On fast estimation of direction of arrival for underwater acoustic target based on sparse Bayesian learning显示文摘The Direction of Arrival(DOA) estimation methods for underwater acoustic target using Temporally Multiple Sparse Bayesian Learning(TMSBL) as the reconstructing algorithm have the disadvantage of slow computing speed.To solve this problem,a fast underwater acoustic target direction of arrival estimation was proposed.Analyzing the model characteristics of block-sparse Bayesian learning framework for DOA estimation,an algorithm was proposed to obtain the value of core hyper-parameter through MacKay's fixed-point method to estimate the DOA.By this process,it will spend less time for computation and provide more superior recovery performance than TMSBL algorithm.Simulation results verified the feasibiUty and effectiveness of the proposed algorithm. | WANG Biao ZHU Zhihui DAI Yuewei | 2017 | Chinese Journal of Acoustics2017，36，1： | 9 |
| 15 | Stent-grafts for the treatment of TIPS dysfunction:Fluency stent vs Wallgraft stent显示文摘AIM:To evaluate the clinical efficacy of an expanded polytetrafluoro-ethylene-covered Fluency stent compared with that of a polyethylene terephthalate-covered Wallgraft stent for the management of transjugular intrahepatic portosystemic shunt(TIPS)dysfunction.METHODS:A retrospective review of patients who underwent TIPS revision with stent-grafts between May 2007 and June 2011 was conducted.The patients were divided into two groups according to the stentgrafts implanted:the Fluency stent(Bard Incorporated,Karlsruhe,Germany)and the Wallgraft stent(Boston Scientific,Galway,Ireland).The primary patency rates were calculated and compared using the Kaplan-Meier method.RESULTS:A total of 73 patients were evaluated in this study:33 with Fluency stents and 40 with Wallgraft stents.The primary patency rates at 12 and 24 mo were 91% and 85%,respectively,in the Fluency stent group and 78% and 63%,respectively,in the Wallgraft stent group.The primary shunt patency rates after TIPS revision were significantly better with the Fluency stent than with the Wallgraft stent(P = 0.033).CONCLUSION:TIPS revision with the Fluency stent has higher medium-term patency rates than that with the Wallgraft stent. | Xue-Feng Luo Ling Nie Zhu Wang Jiaywei Tsauo Ling-Jun Liu Yang Yu Biao Zhou Cheng-Wei Tang Xiao Li | 2013 | World Journal of Gastroenterology2013，19，30： | 9 |
| 16 | Normal Structure and Function of Endothecium Chloroplasts Maintained by ZmMs33-Mediated Lipid Biosynthesis in Tapetal Cells Are Critical for Anther Development in Maize显示文摘Genic male sterility(GMS)is critical for heterosis utilization and hybrid seed production.Although GMS mutants and genes have been studied extensively in plants,it has remained unclear whether chloroplast-associated photosynthetic and metabolic activities are involved in the regulation of anther development.In this study,we characterized the function of ZmMs33/ZmGPAT6,which encodes a member of the glycerol-3-phosphate acyltransferase(GPAT)family that catalyzes the first step of the glycerolipid synthetic pathway.We found that normal structure and function of endothecium(En)chloroplasts maintained by ZmMs33-mediated lipid biosynthesis in tapetal cells are crucial for maize anther development.ZmMs33 is expressed mainly in the tapetum at early anther developmental stages and critical for cell proliferation and expansion at late stages.Chloroplasts in En cells of wild-type anthers function as starch storage sites before stage 10 but as photosynthetic factories since stage 10 to enable starch metabolism and carbohydrate supply.Loss of ZmMs33 function inhibits the biosynthesis of glycolipids and phospholipids,which are major components of En chloroplast membranes,and disrupts the development and function of En chloroplasts,resulting in the formation of abnormal En chloroplasts containing numerous starch granules.Further analyses reveal that starch synthesis during the day and starch degradation at night are greatly suppressed in the mutant anthers,leading to carbon starvation and low energy status,as evidenced by low trehalose-6-phosphate content and a reduced ATP/AMP ratio.The energy sensor and inducer of autophagy,SnRK1,was activated to induce early and excessive autophagy,premature PCD,and metabolic reprogramming in tapetal cells,finally arresting the elongation and development of mutant anthers.Taken together,our results not only show that ZmMs33 is required for normal structure and function of En chloroplasts but also reveal that starch metabolism and photosynthetic activities of En chloroplasts at different developmental stages are essential for normal anther development.These findings provide novel insights for understanding how lipid biosynthesis in the tapetum,the structure and function of En chloroplasts,and energy and substance metabolism are coordinated to maintain maize anther development. | Taotao Zhu Ziwen Li Xueli An Yan Long Xiaofeng Xue Ke Xie Biao Ma Danfeng Zhang Yijian Guan Canfang Niu Zhenying Dong Quancan Hou Lina Zhao Suowei Wu Jinping Li Weiwei Jin Xiangyuan Wan | 2020 | Molecular Plant2020，13，11： | 9 |
| 17 | Parkin promotes proteasomal degradation of p62: implication of selective vulnerability of neuronal cells in the pathogenesis of Parkinson's disease显示文摘 | Pingping Song Shanshan Li Hao Wu Ruize Gao Guanhua Rao Dongmei Wang Ziheng Chen Biao Ma Hongxia Wang Nan Sui Haiteng Deng Zhuohua Zhang Tieshan Tang Zheng Tan Zehan Han Tieyuan Lu Yushan Zhu Quan Chen | 2016 | Protein & Cell2016，7，2： | 8 |
| 18 | Recent progress of integrated circuits and optoelectronic chips显示文摘Integrated circuits(ICs)and optoelectronic chips are the foundation stones of the modern information society.The IC industry has been driven by the so-called'Moore's law'in the past 60 years,and now has entered the post Moore's law era.In this paper,we review the recent progress of ICs and optoelectronic chips.The research status,technical challenges and development trend of devices,chips and integrated technologies of typical IC and optoelectronic chips are focused on.The main contents include the development law of IC and optoelectronic chip technology,the IC design and processing technology,emerging memory and chip architecture,brain-like chip structure and its mechanism,heterogeneous integration,quantum chip technology,silicon photonics chip technology,integrated microwave photonic chip,and optoelectronic hybrid integrated chip. | Yue HAO Shuiying XIANG Genquan HAN Jincheng ZHANG Xiaohua MA Zhangming ZHU Xingxing GUO Yahui ZHANG Yanan HAN Ziwei SONG Yan LIU Ling YANG Hong ZHOU Jiangyi SHI Wei ZHANG Min XU Weisheng ZHAO Biao PAN Yangqi HUANG Qi LIU Yimao CAI Jian ZHU Xin OU Tiangui YOU Huaqiang WU Bin GAO Zhiyong ZHANG Guoping GUO Yonghua CHEN Yong LIU Xiangfei CHEN Chunlai XUE Xingjun WANG Lixia ZHAO Xihua ZOU Lianshan YAN Ming LI | 2021 | Science China(Information Sciences)2021，64，10： | 7 |
| 19 | Development of a monocular vision system for robotic drilling显示文摘Robotic drilling for aerospace structures demands a high positioning accuracy of the robot, which is usually achieved through error measurement and compensation. In this paper, we report the development of a practical monocular vision system for measurement of the relative error between the drill tool center point(TCP) and the reference hole. First, the principle of relative error measurement with the vision system is explained, followed by a detailed discussion on the hardware components, software components, and system integration. The elliptical contour extraction algorithm is presented for accurate and robust reference hole detection. System calibration is of key importance to the measurement accuracy of a vision system. A new method is proposed for the simultaneous calibration of camera internal parameters and hand-eye relationship with a dedicated calibration board. Extensive measurement experiments have been performed on a robotic drilling system. Experimental results show that the measurement accuracy of the developed vision system is higher than 0.15 mm, which meets the requirement of robotic drilling for aircraft structures. | Wei-dong ZHU Biao MEI Guo-rui YAN Ying-lin KE | 2014 | Journal of Zhejiang University-Science C(Computers and Electronics)2014，15，8： | 7 |
| 20 | The genome of Medicago polymorpha provides insights into its edibility and nutritional value as a vegetable and forage legume显示文摘Medicago polymorpha is a nutritious and palatable forage and vegetable plant that also fixes nitrogen.Here,we reveal the chromosome-scale genome sequence of M.polymorpha using an integrated approach including Illumina,PacBio and Hi-C technologies.We combined PacBio full-length RNA-seq,metabolomic analysis,structural anatomy analysis and related physiological indexes to elucidate the important agronomic traits of M.polymorpha for forage and vegetable usage.The assembled M.polymorpha genome consisted of 457.53Mb with a long scaffold N50 of 57.72Mb,and 92.92%(441.83Mb)of the assembly was assigned to seven pseudochromosomes.Comparative genomic analysis revealed that expansion and contraction of the photosynthesis and lignin biosynthetic gene families,respectively,led to enhancement of nutritious compounds and reduced lignin biosynthesis in M.polymorpha.In addition,we found that several positively selected nitrogen metabolism-related genes were responsible for crude protein biosynthesis.Notably,the metabolomic results revealed that a large number of flavonoids,vitamins,alkaloids,and terpenoids were enriched in M.polymorpha.These results imply that the decreased lignin content but relatively high nutrient content of M.polymorpha enhance its edibility and nutritional value as a forage and vegetable.Our genomic data provide a genetic basis that will accelerate functional genomic and breeding research on M.polymorpha as well as other Medicago and legume plants. | Jiawen Cui Zhaogeng Lu Tianyi Wang Gang Chen Salma Mostafa Hailong Ren Sian Liu Chunxiang Fu Li Wang Yingfang Zhu Jinkai Lu Xiang Chen Zhenwu Wei Biao Jin | 2021 | Horticulture Research2021，8，1： | 6 |
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