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| 1 | Recent Advances in Dissecting Stress-Regulatory Crosstalk in Rice显示文摘关於生命、不能生活的压力在世界范围的庄稼生产率上强加严肃的限制。到应力的一种类型的优先或同时的暴露经常影响植物反应到另外的压力,显示在表明小径的压力反应之间的广泛的重叠和串音。集成大 genomic 和 proteomic 数据集合的系统生物学途径便于管理这压力规章的串音的候选人基因的鉴定。最近,我们构造了酵母在控制反应到关於生命、不能生活的压力的三米饭蛋白质附近的二混血儿的地图,也就是有免疫力的受体 XA21,授与抵抗到克否定的细菌, Xanthomonas oryzae pv。oryzae;NH1, NPR1 的米饭 ortholog,全身的获得的抵抗的一个关键管理者;并且乙烯应答的抄写因素, SUB1A,它授与公差浸没应力。这些研究结合了介绍的 transcriptional ,合作表示分析识别了在关於生命、不能生活的压力回答的接口被放的蛋白质的一间套房,包括 激活mitogen 的蛋白质 kinase 5 ( OsMPK5 ),联系墙的 kinase 25 ( WAK25 ),蔗糖 non-fermenting-1-related 蛋白质 kinase-1 ( SnRK1 ), SUB1A 绑定蛋白质 23 ( SAB23 ),并且几个 WRKY 家庭抄写因素。新兴的证据建议这些基因通过许多机制安排在关於生命、不能生活的压力之间的串音,包括细胞的精力动态平衡和在压力荷尔蒙水杨酸酸,乙烯, jasmonic 酸,和 abscisic 酸之间的 synergistic 或对抗相互作用的修正的规定。 | Rita Sharma | 2013 | Molecular Plant2013，6，2： | 9 |
| 2 | Phacoemulsification versus small incision cataract surgery in patients with uveitis显示文摘AIM: To compare the safety and efficacy of phacoemulsification and small incision cataract surgery(SICS) in patients with uveitic cataract.·METHODS: In a prospective, randomized multi-centric study, consecutive patients with uveitic cataract were randomized to receive phacoemulsification or manual SICS by either of two surgeons well versed with both the techniques. A minimum inflammation free period of 3mo(defined as less than 5 cells per high power field in anterior chamber) was a pre-requisite for eligibility for surgery. Superior scleral tunnel incisions were used for both techniques. Improvement in visual acuity post-operatively was the primary outcome measure and the rate of post-operative complications and surgical time were secondary outcome measures, respectively. Means of groups were compared using t-tests. One way analysis of variance(ANOVA) was used when there were more than two groups. Chi-square tests were used for proportions. Kaplan Meyer survival analysis was done and means for survival time was estimated at 95%confidence interval(CI). A P value of <0.05 was considered statistically significant.·RESULTS: One hundred and twenty-six of 139 patients(90.6%) completed the 6-month follow-up. Seven patients were lost in follow up and another six excluded due to either follow-up less than six months(n=1) or inability implant an intraocular lens(IOL) because of insufficient capsular support following posterior capsule rupture(n=5). There was significant improvement in vision after both the procedures(paired t-test; P <0.001). On first postoperative day, uncorrected distance visual acuity(UDVA) was 20/63 or better in 31(47%)patients in Phaco group and 26(43.3%) patients in SICS group(P=0.384). The mean surgically inducedastigmatism(SIA) was 0.86 ±0.34 dioptres(D) in the phacoemulsification group and 1.16 ±0.28 D in SICS group. The difference between the groups was significant(t-test, P =0.002). At 6mo, corrected distance visual acuity(CDVA) was 20/60 or better in 60(90.9%) patients in Phaco group and 53(88.3%) in the manual SICS group(P =0.478). The mean surgical time was significantly shorter in the manual SICS group(10.8±2.9 versus 13.2±2.6min)(P <0.001). Oral prednisolone, 1 mg/kg body weight was given 7d prior to surgery, continued post-operatively and tapered according to the inflammatory response over 4-6wk in patients with previously documented macular edema, recurrent uveitis, chronic anterior uveitis and intermediate uveitis. Rate of complications like macular edema(Chi-square, P =0.459),persistent uveitis(Chi-square, P =0.289) and posterior capsule opacification(Chi-square, P =0.474) were comparable between both the groups.·CONCLUSION: Manual SICS and phacoemulsification do not differ significantly in complication rates and final CDVA outcomes. However, manual SICS is significantly faster. It may be the preferred technique in settings where surgical volume is high and access to phacoemulsification is limited, such as in eye camps. It may also be the appropriate technique for uveitic cataract under such circumstances. | Rahul Bhargava Prachi Kumar Shiv Kumar Sharma Manoj Kumar Avinash Kaur | 2015 | International Journal of Ophthalmology(English edition)2015，8，5： | 8 |
| 3 | WISH:wavefront imaging sensor with high resolution显示文摘Wavefront sensing is the simultaneous measurement of the amplitude and phase of an incoming optical field.Traditional wavefront sensors such as Shack-Hartmann wavefront sensor(SHWFS)suffer from a fundamental tradeoff between spatial resolution and phase estimation and consequently can only achieve a resolution of a few thousand pixels.To break this tradeoff,we present a novel computational-imaging-based technique,namely,the Wavefront Imaging Sensor with High resolution(WISH).We replace the microlens array in SHWFS with a spatial light modulator(SLM)and use a computational phase-retrieval algorithm to recover the incident wavefront.This wavefront sensor can measure highly varying optical fields at more than 10-megapixel resolution with the fine phase estimation.To the best of our knowledge,this resolution is an order of magnitude higher than the current noninterferometric wavefront sensors.To demonstrate the capability of WISH,we present three applications,which cover a wide range of spatial scales.First,we produce the diffraction-limited reconstruction for long-distance imaging by combining WISH with a large-aperture,low-quality Fresnel lens.Second,we show the recovery of high-resolution images of objects that are obscured by scattering.Third,we show that WISH can be used as a microscope without an objective lens.Our study suggests that the designing principle of WISH,which combines optical modulators and computational algorithms to sense high-resolution optical fields,enables improved capabilities in many existing applications while revealing entirely new,hitherto unexplored application areas. | Yicheng Wu Manoj Kumar Sharma Ashok Veeraraghavan | 2019 | Light(Science & Applications)2019，8，1： | 6 |
| 4 | First results on ^(76)Ge neutrinoless double beta decay from CDEX-1 experiment显示文摘We report the first results on ^(76)Ge neutrinoless double beta decay from stage one of the China dark-matter experiment(CDEX).A p-type point-contact high-purity germanium detector with a mass of 994 g has been installed to detect neutrinoless double beta decay events, as well as to directly detect dark matter particles. An exposure of 304 kg d has been analyzed over a wide spectral band from 500 keV to 3 MeV. The average event rate obtained was about 0.012 counts per keV per kg per day over the 2.039 MeV energy range. The half-life of ^(76)Ge neutrinoless double beta decay derived based on this result is T^(0ν)1/2>6.4×10^(22) yr(90% C.L.). An upper limit on the effective Majorana-neutrino mass of 5.0 eV has been achieved. | Li Wang Qian Yue KeJun Kang JianPing Cheng YuanJing Li TszKing Henry Wong ShinTed Lin JianPing Chang JingHan Chen QingHao Chen YunHua Chen Zhi Deng Qiang Du Hui Gong Li He QingJu He JinWei Hu HanXiong Huang TengRui Huang LiPing Jia Hao Jiang HauBin Li Hong Li JianMin Li Jin Li Jun Li Xia Li XueQian Li YuLan Li FongKay Lin ShuKui Liu Hao Ma JingLu Ma XingYu Pan Jie Ren XiChao Ruan ManBin Shen Vivek Sharma Lakhwinder Singh Manoj Kumar Singh Manoj Kumar Singh Arun Kumar Soma ChangJian Tang WeiYou Tang ChaoHsiung Tseng JiMin Wang Qing Wang ShiYong Wu YuCheng Wu HaoYang Xing Yin Xu Tao Xue LiTao Yang SongWei Yang Nan Yi ChunXu Yu HaiJun Yu WeiHe Zeng XiongHui Zeng Zhi Zeng Lan Zhang YunHua Zhang MingGang Zhao Wei Zhao JiFang Zhou ZuYing Zhou JingJun Zhu WeiBin Zhu ZhongHua Zhu | 2017 | Science China(Physics,Mechanics & Astronomy)2017，60，7： | 3 |
| 5 | Hepatic and systemic hemodynamic derangements predict early mortality and recovery in patients with acute‐on‐chronic liver failure显示文摘 | Hitendra Garg Ashish Kumar Vishal Garg Manoj Kumar Ramesh Kumar Barjesh Chander Sharma Shiv Kumar Sarin | 2013 | J Gastroenterol Hepatol2013，，8： | 2 |
| 6 | Analysis of dose–volume parameters predicting radiation pneumonitis in patients with esophageal cancer treated with 3D-conformal radiation therapy or IMRT显示文摘 | Gaurav Kumar Sheh Rawat Abhishek Puri Manoj Kumar Sharma Pranav Chadha Anand Giri Babu Girigesh Yadav | 2012 | Japanese Journal of Radiology2012，，1： | 2 |
| 7 | Circulatory and hepatic failure at admission predicts mortality of severe scrub typhus patients: A prospective cohort study显示文摘Objective:To study the spectrum and outcome of severe scrub typhus in adult patients and to predict the hospital mortality by organ failure on admission.Methods:This was a prospective observational cohort study conducted between July 2017 and October 2020 at the medical emergency centre of PGIMER,Chandigarh,India.One hundred and twenty-six patients aged≥13 years were diagnosed with scrub typhus.Severe disease was defined as the presence of organ failure based on the Sequential Organ Failure Assessment(SOFA)score on admission.Results:About two-thirds of the patients were from geographic regions outside the endemic sub-Himalayan belt.Fever(99.21%)and dyspnea(79.36%)were the most frequent complaints.Respiratory failure(81.75%)was the most common organ failure,followed by hepatic(52.38%),coagulative(47.62%),circulatory(33.33%),renal(21.43%),and cerebral dysfunction(13.49%).The median(Q1,Q3)SOFA score was 8(6,9),and 48.41%of the patients had a quick-SOFA score≥2.Organ supports with invasive ventilation(40.48%),vasopressors(36.51%),and renal replacement therapy(7.14%)were frequently required.The in-hospital mortality was 11.90% and was independently predicted by circulatory and hepatic failures on multivariate logistic regression(OR 11.12,95%CI 1.73-71.31 and OR 8.49,95%CI 1.18-61.41,respectively).Conclusions:Most patients had pulmonary dysfunction;circulatory or hepatic failure on admission strongly predicts death. | Ashok Kumar Pannu Atul Saroch Saurabh Chandrabhan Sharda Manoj Kumar Debnath Manisha Biswal Navneet Sharma | 2021 | Asian Pacific Journal of Tropical Medicine2021，14，5： | 2 |
| 8 | 中国孕妇生育二胎的影响因素:基于医院的横断面调查显示文摘目的探索中国孕妇生育二胎的影响因素及潜在原因。设计本研究为基于医院的横断面调查。地点中国5个省的16家医院。样本2015年6月至8月。通过访谈式问卷调查法调查2345名年龄≥18岁的孕妇。主要结局指标孕妇胎次(初胎孕妇或二胎孕妇)和生育二胎的原因。结果此研究共包含1755名(74.8%)初胎孕妇以及590名(25.2%)二胎孕妇。二胎孕妇孕育二胎最常见的原因包括“为了第一个孩子好”(26.1%)、“喜欢孩子”(25.8%)、“顺应二胎政策”(11.5%)、“担心失独”(7.5%)以及“父母的建议”(7.5%)。低等教育水平[现患比(PR)1.96;95%可信区间(CI)1.62-2.36]和中等教育水平(PR1.97;95%CI1.65-2.36)的孕妇相对受过高等教育的孕妇更可能生育二胎。其中,由于“二胎政策”的影响,中等教育水平的妇女生育二胎的人数是低等教育水平的3倍。家庭人均月收入水平与二胎生育意愿呈负相关,但是失业的受调查者(PR0.79;95%CI0.66-0.951比非失业者生育二胎的可能性更小。结论研究人群中四分之一的孕妇为二胎孕妇。“为第一个孩子好”及“喜爱孩子”是促使受调查者生育二胎的主要原因。低社会经济地位和二胎生育意愿呈正相关。新出台的二胎政策将会对中国的人口结构产生影响。 | 徐祥龙 左寒晓 史祖民 饶运双 王炼炼 曾缓 张磊 Manoj Sharma Cesar Reis 赵勇 | 2017 | 英国医学杂志中文版2017，20，8： | 2 |
| 9 | The type and mysorensis forms of the Anopheles stephensi (Diptera: Culicidae) in India exhibit identical ribosomal DNA ITS2 and domain-3 sequences显示文摘 | Mohammad Tauqeer Alam Hema Bora Manoj K. Das Yagya D. Sharma | 2008 | Parasitology Research2008，，1： | 1 |
| 10 | Plants as bioreactors: Recent developments and emerging opportunities显示文摘 | Arun K. Sharma Manoj K. Sharma | 2009 | Biotechnology Advances2009，，6： | 1 |
| 11 | Stratifying Risk of Biliary Complications in Adult Living Donor Liver Transplantation by Magnetic Resonance Cholangiography显示文摘 | Randeep Kashyap Adel Bozorgzadeh Peter Abt Georgios Tsoulfas Manoj Maloo Rajeev Sharma Siddharth Patel David Dombroski Parvez Mantry Saman Safadjou Ashok Jain Mark Orloff | 2008 | Transplantation2008，，11： | 1 |
| 12 | Measuring dimensions of manufacturing flexibility显示文摘 | Lori L Koste Manoj K Malhotra Subhash Sharma | 2004 | Journal of Operations Management2004，22，2： | 1 |
| 13 | Liver Stiffness Measurements in Patients with Different Stages of Nonalcoholic Fatty Liver Disease: Diagnostic Performance and Clinicopathological Correlation显示文摘 | Ramesh Kumar Archana Rastogi Manoj Kumar Sharma Vikram Bhatia Pankaj Tyagi Praveen Sharma Hitendra Garg K. N. Chandan Kumar Chhagan Bihari Shiv Kumar Sarin | 2013 | Digestive Diseases and Sciences2013，，1： | 1 |
| 14 | Differentiating Acute Hepatitis B from the First Episode of Symptomatic Exacerbation of Chronic Hepatitis B显示文摘 | Manoj Kumar Sanjay Jain Barjesh Chander Sharma Shiv Kumar Sarin | 2006 | Digestive Diseases and Sciences2006，，3： | 1 |
| 15 | Tuberculosis of the Craniovertebral Junction: Is Surgery Necessary?显示文摘 | Sunil K. Gupta Sandeep Mohindra Bhawani S. Sharma Rahul Gupta Rajesh Chhabra Kanchan K. Mukherjee Manoj K. Tewari Ashis Pathak Niranjan Khandelwal Narain M. Suresh Virender K. Khosla | 2006 | Neurosurgery2006，，6： | 1 |
| 16 | Abstract T P344:clopidogrel resistance in stroke patients(The CRISP Trial)显示文摘 | Manoj A L Fitzsimmons P R Sharma N | 2014 | Stroke2014，45，1： | 1 |
| 17 | Often a missed type of pancreatitis: groove pancreatitis显示文摘 | Pankaj Tyagi Shalini Thaper Vikram Bhatia Manoj Sharma | 2012 | Indian Journal of Gastroenterology2012，，4： | 1 |
| 18 | Limits on light WIMPs with a 1 kg-scale germanium detector at 160 eVee physics threshold at the China Jinping Underground Laboratory显示文摘We report results of a search for light weakly interacting massive particle(WIMP) dark matter from the CDEX-1 experiment at the China Jinping Underground Laboratory(CJPL). Constraints on WIMP-nucleon spin-independent(SI) and spin-dependent(SD) couplings are derived with a physics threshold of 160 eVee, from an exposure of 737.1 kg-days. The SI and SD limits extend the lower reach of light WIMPs to 2 GeV and improve over our earlier bounds at WIMP mass less than 6 GeV. | 杨丽桃 李浩斌 岳骞 康克军 程建平 李元景 王子敬 M.Agartioglu 安海鹏 常建平 陈景瀚 陈云华 邓智 杜强 宫辉 何力 胡津纬 胡庆东 黄瀚雄 贾历平 江灏 李红 李荐民 李金 李霞 李学潜 李玉兰 林枫凯 林兴德 刘书魁 刘仲智 马豪 马菁露 潘辉 任杰 阮锡超 B.Sevda Vivek Sharma 申满斌 Lakhwinder Singh Manoj Kumar Singh 唐昌建 唐维优 田阳 王继敏 王力 王青 王轶 吴世勇 吴玉成 幸浩洋 徐音 薛涛 杨松伟 易难 喻纯旭 于海军 岳剑峰 曾雄辉 曾鸣 曾志 张云华 赵明刚 赵伟 周济芳 周祖英 朱敬军 朱忠华 | 2018 | Chinese Physics C2018，42，2： | 1 |
| 19 | Identification of Mycobacterium tuberculosis genes preferentially expressed during human infection显示文摘 | Manoj Kumar Farrah G. Khan Sandeep Sharma Rajinder Kumar Jaya Faujdar Rahul Sharma Devendra S. Chauhan Rajinder Singh Shyam K. Magotra Inshad A. Khan | 2010 | Microbial Pathogenesis2010，，1： | 1 |
| 20 | PSO Based Multi-Objective Approach for Controlling PID Controller显示文摘CSTR(Continuous stirred tank reactor)is employed in process control and chemical industries to improve response characteristics and system efficiency.It has a highly nonlinear characteristic that includes complexities in its control and design.Dynamic performance is compassionate to change in system parameterswhich need more effort for planning a significant controller for CSTR.The reactor temperature changes in either direction from the defined reference value.It is important to note that the intensity of chemical actions inside the CSTR is dependent on the various levels of temperature,and deviation from reference values may cause degradation of biomass quality.Design and implementation of an appropriate adaptive controller for such a nonlinear system are essential.In this paper,a conventional Proportional Integral Derivative(PID)controller is designed.The conventional techniques to deal with constraints suffer severe limitations like it has fixed controller parameters.Hence,A novel method is applied for computing the PID controller parameters using a swarm algorithm that overcomes the conventional controller’s limitation.In the proposed technique,PID parameters are tuned by Particle Swarm Optimization(PSO).It is not easy to choose the suitable objective function to design a PID controller using PSO to get an optimal response.In this article,a multi-objective function is proposed for PSO based controller design of CSTR. | Harsh Goud Prakash Chandra Sharma Kashif Nisar Ag.Asri Ag.Ibrahim Muhammad Reazul Haque Narendra Singh Yadav Pankaj Swarnkar Manoj Gupta Laxmi Chand | 2022 | Computers, Materials & Continua2022，，6： | 1 |
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