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    题名 作者 年代 出处 被引量
1Experimental investigation of the influence of electric field on frost layer growth under natural convection condition显示文摘直接电流(DC ) 的影响一个冷垂直盘子上的霜的厚度和团上的电场被调查。生长有或没有电场的存在被拿,并且结果的霜层的相片证明电走在霜厚度上有强烈影响。霜厚度和霜质量上的冷板温度和周围的温度的影响也与电场在自然传送对流条件下面被调查。试验性的结果证明冷板温度在霜层厚度,而是它对霜质量的影响上有很强壮的效果是次要的;对霜团的影响或周围的温度在霜厚度上是比那更明显的。ZHANG Xinhua, LIU Zhongliang, WANG Jieteng, GOU Yujun, MENG Sheng and MA Chongfang Key Laboratory of Enhanced Heat Transfer and Energy Conservation, Ministry of Education Key Laboratory of Heat Transfer and Energy Conversion, Beijing Education Commission, Beijing University of Technology, Beijing 100022, China 2006Progress in Natural Science:Materials International2006,16,4:16
2Influence of Processing Conditions on Microstructure and Mechanical Properties of Large Thin-Wall Centrifugal Ti–6Al–4V Casting显示文摘在这个工作,包括张力的静电干扰和扔的大薄墙的圆柱的 Ti-6Al-4V 的损坏忍耐性质,温度并且热均衡说的紧迫(HIPping ) 在微结构特征和机械性质上处理的模子预热的效果被学习了。试验性的结果显示出那,增加的模子预热从 673 的温度到 873K,扔的微观结构从 Widmanst 的混合物变化 ? tten 和殖民地微观结构到一个主要殖民地。厚墙节的中心比边和薄节有相对粗糙的微观结构。更低的模子预热温度引起更多的孔。HIPping 过程,它不仅有效地减少扔的毛孔而且增加优先的谷物边界结合并且变粗微观结构,对改进扔的韧性必要。由于表面上的氧污染和更好的微观结构,生气的节上的微坚硬的侧面从表面介绍一个减少的趋势给内部。为预热的不同模子的反应层的厚度温度将近一样(~ 450 畃洠捩潲 ' 跍?湩琠敨戠楬摮栠汯? 楷桴愠搠慩敭整 ? 景 ? 0?Xin Feng Jianke Qiu Yingjie Ma Jiafeng Lei Yuyou Cui Xinhua Wu Rui Yang 2016Journal of Materials Science & Technology2016,32,4:9
3Cluster observations of large-scale southward movement and dawnward-duskward flapping of Earth's magnetotail current sheet显示文摘In August 2001,Cluster satellites observed that the mid-tail current sheet(CS) moved southward continuously for almost seven hours.Meanwhile,Cluster crossed back and forth the CS repeatedly.This means that the large-scale southward movement of the CS was accompanied by a small-scale CS flapping during this period.Using the minimum-variation-analysis(MVA) method and the multi-spacecraft data,we calculated the normal vector,current density and the magnetic curvature of the CS,the results showed that the CS alternated between flattened CS and tilted CS for several times.Strong dawn-dusk oscillations were found for the tilted CS,which caused the repeated crossings of the center of CS by the satellites.This feature is obviously different from the previous observations of the vertical flapping of the CS induced by the kink instability.Two types of flapping were observed:One of them is accompanied with bursty bulk flows(BBFs) and the other is not.This suggests that in this event there was no direct relationship between the CS flapping and BBFs.DUAN AiYing CAO JinBin MA YuDuan WEI XinHua 2013Science China(Technological Sciences)2013,56,1:6
4Economic evaluation of cervical cancer screening strategies in urban China显示文摘Objective:This study evaluated the feasibility of different cervical cancer screening strategies in urban China.Methods:A Markov model was constructed to simulate a hypothetical cohort of 100,000 females aged 30-59 years in a 20-year period.Screening strategies included liquid-based cytology(LBC)every three years,human papillomavirus(HPV)DNA testing every three and five years,respectively,and a combination of HPV DNA testing and LBC(HPV+LBC)every three and five years,respectively.Model outcomes included cumulative incidence over 20 years,cumulative risk of cervical cancer,costs,life year saved(LYS),quality-adjusted life years(QALYs)and benefits.The cost-effectiveness ratios(CERs),incremental cost-effectiveness ratios(ICERs),costutility ratios(CURs),and benefit-cost ratios(BCRs)were used as outcomes in the health economic evaluation analysis.Univariate sensitivity analyses were performed to examine the stability of the results.Results:The cumulative incidence of the five screening strategies ranged from 833.02 to 1,158.07 cases per100,000 females.HPV DNA testing was most effective in reducing the cumulative risk of cervical cancer,saving life years and QALYs and gaining benefits.The CERs of HPV DNA testing every three and five years,and LBC every three years were considered to be very cost-effective if they were below China's GDP per capita.The CERs of HPV+LBC were considered to be cost-effective if they were below three times GDP per capita.The incremental cost-effectiveness analysis showed that HPV DNA testing every three and five years,LBC every three years and HPV+LBC every five years were dominant strategies.Conclusions:The findings of this study indicated that HPV DNA testing every five years or LBC every three years should be recommended in urban China.Li Ma Yuying Wang Xiaohong Gao Yi Dai Yu Zhang Zhaojing Wang Xiaoxia Wang Limin Wang Jing Jiang Xinhua Jing Chunxia Yang Fanghui Zhao Jinghe Lang Youlin Qiao 2019Chinese Journal of Cancer Research2019,31,6:4
5Effects of extracts from Chuanwu(Aconitum Carmichaelii) and Banxia(Rhizoma Pinelliae) on excisional wound healing in a rat's model显示文摘OBJEVTIVE: To investigate the effects of extracts from Chuanwu(Aconitum Carmichaelii) and Banxia(Rhizoma Pinelliae) on the excisional wound healing in a rat's model.METHODS: Rats were performed a surgical lesion with a 2.0 cm resected tissue in the dorsal fascia.Following, animals were randomly divided into model group, YNB group and APE group those were respectively treated with saline, 1 mg/mL of Yunnan Baiyao and 1 mg/mL of Chuanwu(Aconitum Carmichaelii) and Banxia(Rhizoma Pinelliae) extracts. Wound contractions in days 0, 3, 7, 14 and 21 were calculated by an image analyzer. Histological analysis was analyzed using hematoxilin and eosin.Levels of tumor necrosis factor-2(IL-2), IL-4, IL-10, transformαin(TNF-g growα), interleukinth factor-1(TGF-nd basic fibroblast growth factor(bFββ1) a-GF) were determined by real-time quantitative PCR.RESULTS: Compared with that of YNB group and APE gtoup, the skin of rats showed poor re-modeling and re-epithelization characterized by a significant decrease of neovascularization, epithelialization and fibroblast in the model group. In the APE group, levels of TNF-α-and IL-2 were significantly down-regulated and IL4 and IL-10 significantly upregulated in contrasted with that of model group.In addition, levels of TGF-roup were significantly iβ1 and bFGF in the APE gnduced compared with that of model group.CONCLUSION: The results suggest that the extracts from Chuanwu(Aconitum Carmichaelii) and Banxia(Rhizoma Pinelliae) promote wound healing in the rats, which is associated with enhancing antiinflammatory ability and inducing fibroblast formation.Xia Xichao Ma Yuhong Wang Fuan Zheng Xinhua Liu Yang Zhang Junfeng Cui Juan Shi Bingqin Li Hongwen Liu Rongzhi Zhang Yaping Cheng Zhaofei Han Xiaolong 2019Journal of Traditional Chinese Medicine2019,39,1:4
6From deep basin gas to diagenetic trap—An example from the Yulin Gas Field in the Ordos Basin显示文摘In the updip portion of the Yulin Gas Field in the Ordos Basin, there are no any structural, stratigraphic and sedimentary lithologic seals. Using thin-section petrography, ultraviolet fluorescence microscopy, micro-thermometry and Raman microspectrometry, this paper finds out the diagenetic trap and studies the diagenetic history of this field. It was revealed that three phases of diagenesis and hydrocarbon charging happened in late Triassic, late Jurassic and the end of early Cretaceous respectively. In the first two phases, acid geofluid entered the reservoir and caused dissolution and cementation. Although the porosities had been increased, further compaction accompanying re-subsidence resulted in tight sandstone and conglomerates. Till the end of the early Cretaceous, bulk of gas migrated into the tight reservoir. Cementation, however, kept on in the updip portion of this field due to low gas saturation and formed the diagenetic trap. The mechanism for gas accumulation was changed from deep basin gas to diagenetic trap, which offers a sealing condition that can retain gas for much longer time.ZHANG LiuPing LUO XiaoRong MA XinHua CHEN MengJin WU MingHui 2007Chinese Science Bulletin2007,52,21:4
7The progress and prospects of shale gas exploration and development in southern Sichuan Basin, SW China显示文摘The Ordovician Wufeng Formation-Silurian Longmaxi Formation organic-rich shales distributed widely and stably in Southern Sichuan Basin were investigated based on drilling data.Geological evaluation of wells show that the shale reservoirs have good properties in the Yibin,Weiyuan,Zigong,Changning,Luzhou,Dazu areas,with key parameters such as TOC,porosity,gas content similar to the core shale gas production zones.Moreover,these areas are stable in structure,good in preservation conditions and highly certain in resources.The shale reservoirs have a burial depth of 4 500 m or shallow,a total area of over 2×10~4 km^2 and estimated resource of over10×10^(12) m^3,so they are the most resource-rich and practical areas for shale gas exploitation in China.Through construction of the Changning-Weiyuan national demonstration region,the production and EUR of shale gas wells increased significantly,the cost of shale gas wells decreased remarkable,resulting in economic benefit better than expected.Moreover,the localized exploration and development technologies and methods are effective and repeatable,so it is the right time for accelerating shale gas exploitation.Based on the production decline pattern of horizontal wells at present and wells to be drilled in the near future,at the end of the 13th Five Year Plan,the production of shale gas in southern Sichuan Basin is expected to reach or exceed 10 billion cubic meters per year.The resources are sufficient for a stable production period at 30 billion cubic meters per year,which will make the South Sichuan basin become the largest production base of shale gas in China.MA Xinhua XIE Jun 2018Petroleum Exploration and Development2018,45,1:3
8Tagging single nucleotide polymorphisms in the PPAR-γ and RXR-α gene and type 2 diabetes risk:a case-control study of a Chinese Han population显示文摘Peroxisome proliferator-activated receptor (PPAR-γ),which is mainly involved in adipocyte differentiation, has been suggested to play an important role in the pathogenesis of insulin resistance and atherosclerosis. We investigated the frequencies of two common tagging polymorphisms of the PPAR-γ gene and two of PPAR-α with minor allele frequency (MAF)≥ 0.05 in the Chinese Han population and analyzed the correlation between the different genotypes and the risk of type 2 diabetes mellitus (T2DM). TaqMan assay was performed to test the genotypes in T2DM patients (n = 1,105) and normal controls (n = 1,107). Serum adiponectin concentration was measured by ELISA kit. The variant genotypes rs17817276GG, rs3856806CT and rs3856806CT/TT of PPAR-γ were associated with T2DM, P = 0.023,0.037 and 0.018, respectively. Furthermore, the prevalence of haplotype GT in PPAR-γ was less frequent in the case subjects (0.3%) than in the controls (1.9%) [P < 0.001,OR(95%CI)=0.13 (0.06-0.31)]. Patients with genotype TT of rs3856806 had a higher serum level of adiponectin than those with the genotype CC and CT (P = 0.031 and 0.038, respectively). There was no statistically significant difference between patients and controls in genotype distribution of rs6537944 and rs1045570 of the RXR-α gene. The present study suggests that the variant genotypes in the PPAR-γ gene could decrease the risk for the development of T2DM in the Chinese Han population.Juan Du Hui Shi Ying Lu Wencong Du Yuanyuan Cao Qian Li Jianhua Ma Xinhua Ye Jinluo Cheng Xiaofang Yu Yanqin Gao Ling Zhou 2011The Journal of Biomedical Research2011,25,1:3
9Chronic fatigue syndrome treated by the traditional Chinese proce-dure abdominal tuina:a randomized controlled clinical trial显示文摘OBJECTIVE: To evaluate the effect of the traditional Chinese procedure abdominal Tuina(AT) on chronic fatigue syndrome(CFS).METHODS: This randomized, single assessor-blinded clinical trial was carried out from May 2014 to April 2015. Eighty participants in the trial were divided randomly into two groups: experimental group and control. The experimental group(40 cases) was treated by AT and the control group(40 cases) by acupuncture. Each treatment was conducted once a day, 5 d for one course, at an interval of 2 d between each course. The whole treatment course lasted for 4 weeks. To ascertain the effect of AT and acupuncture, Fatigue Scale-14(FS-14), Self-rating Anxiety Scale(SAS) and Hamilton Rating Scale for Depression(HAMD) scores were used before and after treatment. Patients were followed up for3 months after treatment.RESULTS: After treatment for 4 weeks, 77 patients(39 cases in the experimental group and 38 cases in the control group) completed the trial. The FS-14,SAS and HAMD scores decreased(P < 0.05) significantly compared with those before treatment in both groups. The FS-14 and HAMD(P < 0.05) scores in the experimental group were much lower than those in the control group. The difference in SAS scores between the two groups was not significant.In the final follow-up, CFS in two cases in the experimental group and three in the control group recurred, but the difference was not significant. The scores for the FS-14, SAS and HAMD in the experimental group were superior to those of the control group, and the difference was significant(P < 0.05).No serious adverse events and few adverse events were observed.CONCLUSION: AT elicited a more efficacious effect than acupuncture alone on CFS.Li Huanan Wang Jingui Zhang Wei Zhao Na Hai Xinhua Sun Shiquan Sun Qing Han Yihao Zhang Runchen Ma Fei 2017Journal of Traditional Chinese Medicine2017,37,6:3
10Application of the back-error propagation artificial neural network(BPANN) on genetic variants in the PPAR-γ and RXR-α gene and risk of metabolic syndrome in a Chinese Han population显示文摘This study was aimed to explore the associations between the combined effects of several polymorphisms in the PPAR-γ and RXR-α gene and environmental factors with the risk of metabolic syndrome by back-error propagation artificial neural network(BPANN).We established the model based on data gathered from metabolic syndrome patients(n = 1012) and normal controls(n = 1069) by BPANN.Mean impact value(MIV) for each input variable was calculated and the sequence of factors was sorted according to their absolute MIVs.Generalized multifactor dimensionality reduction(GMDR) confirmed a joint effect of PPAR-γ and RXR-α based on the results from BPANN.By BPANN analysis,the sequences according to the importance of metabolic syndrome risk factors were in the order of body mass index(BMI).serum adiponectin,rs4240711,gender,rs4842194,family history of type 2 diabetes,rs2920502,physical activity,alcohol drinking,rs3856806,family history of hypertension,rsl045570,rs6537944,age,rsl7817276,family history of hyperlipidemia,smoking,rs1801282 and rs3132291.However,no polymorphism was statistically significant in multiple logistic regression analysis.After controlling for environmental factors,A_1,A_2,B_1 and B_2(rs4240711,rs4842194,rs2920502 and rs3856806) models were the best models(cross-validation consistency 10/10,P = 0.0107) with the GMDR method.In conclusion,the interaction of the PPAR-γ and RXR-α gene could play a role in susceptibility to metabolic syndrome.A more realistic model is obtained by using BPANN to screen out determinants of diseases of multiple etiologies like metabolic syndrome.Xu Zhao Kang Xu Hui Shi Jinluo Cheng Jianhua Ma Yanqin Gao Qian Li Xinhua Ye Ying Lu Xiaofang Yu Juan Du Wencong Du Qing Ye Ling Zhou 2014The Journal of Biomedical Research2014,28,2:3
11Transcriptomics and metabolomics analyses provide insights into postharvest ripening and senescence of tomato fruit under low temperature显示文摘Tomato is one of the most important vegetable crops in the world and is a model plant used to study the ripening of climacteric fleshy fruit.During the ripening process of tomato fruit,flavor and aroma metabolites,color,texture and plant hormones undergo significant changes.However,low temperatures delayed the ripening process of tomato fruit,inhibiting flavor compounds and ethylene production.Metabolomics and transcriptomics analyses of tomato fruit stored under low temperature(LT,5°C)and room temperature(RT,25°C)were carried out to investigate the effects of storage temperature on the physiological changes in tomato fruit after harvest.The results of transcriptomics changes revealed that the differentially expressed genes(DEGs)involved in tomato fruit ripening,including several kinds of transcription factors(TFs)(TCP,WRKY,MYB and bZIP),enzymes involved in cell wall metabolism[beta-galactosidase(β-GAL),pectinesterase(PE)and pectate lyase(PL),cellulose and cellulose synthase(CESA)],enzymes associated with fruit flavor and aroma[acetyltransferase(AT),malic enzyme(ME),lipoxygenase(LOX),aldehyde dehydrogenase(ALDH),alcohol dehydrogenase(ADH)and hexokinase(HK)],genes associated with heat stress protein 70 and genes involved in the production of plant hormones such as Ethylene responsive factor 1(ERF1),Auxin/indoleacetic acids protein(AUX/IAA),gibberellin regulated protein.Based on the above results,we constructed a regulatory network model of the effects of different temperatures during the fruit ripening process.According to the analysis of the metabolomics results,it was found that the contents of many metabolites in tomato fruit were greatly affected by storage temperature,including,organic acids(L-tartaric acid,a-hydroxyisobutyric acid and 4-acetamidobutyric acid),sugars(melezitose,beta-Dlactose,D-sedoheptulose 7-phosphate,2-deoxyribose 1-phosphate and raffinose)and phenols(coniferin,curcumin and feruloylputrescine).This study revealed the effects of storage temperature on postharvest tomato fruit and provided a basis for further understanding of the molecular biology and biochemistry of fruit ripening.Chunmei Bai Caie Wu Lili Ma Anzhen Fu Yanyan Zheng Jiawei Han Changbao Li Shuzhi Yuan Shufang Zheng Lipu Gao Xinhua Zhang Qing Wang Demei Meng Jinhua Zuo 2023Horticultural Plant Journal2023,9,1:3
12Key technologies and practice for gas field storage facility construction of complex geological conditions in China显示文摘In view of complex geological characteristics and alternating loading conditions associated with cyclic large amount of gas injection and withdrawal in underground gas storage(UGS) of China, a series of key gas storage construction technologies were established, mainly including UGS site selection and evaluation, key index design, well drilling and completion, surface engineering and operational risk warning and assessment, etc. The effect of field application was discussed and summarized. Firstly, trap dynamic sealing capacity evaluation technology for conversion of UGS from the fault depleted or partially depleted gas reservoirs. A key index design method mainly based on the effective gas storage capacity design for water flooded heterogeneous gas reservoirs was proposed. To effectively guide the engineering construction of UGS, the safe well drilling, high quality cementing and high pressure and large flow surface injection and production engineering optimization suitable for long-term alternate loading condition and ultra-deep and ultra-low temperature formation were developed. The core surface equipment like high pressure gas injection compressor can be manufactured by our own. Last, the full-system operational risk warning and assessment technology for UGS was set up. The above 5 key technologies have been utilized in site selection, development scheme design, engineering construction and annual operations of 6 UGS groups, e.g. the Hutubi UGS in Xinjiang. To date, designed main indexes are highly consistent with actural performance, the 6 UGS groups have the load capacity of over 7.5 billion cubic meters of working gas volume and all the storage facilities have been running efficiently and safely.MA Xinhua ZHENG Dewen SHEN Ruichen WANG Chunyan LUO Jinheng SUN Junchang 2018Petroleum Exploration and Development2018,45,3:2
13Aluminum hydride for solid-state hydrogen storage:Structure,synthesis, thermodynamics, kinetics, and regeneration显示文摘Aluminum hydride(AlH3) is a binary metal hydride that contains more than 10.1 wt% of hydrogen and possesses a high volumetric hydrogen density of 148 kg H2 m^(-3).Pristine AlH3 can readily release hydrogen at a moderate temperature below 200℃.Such high hydrogen density and low desorption temperature make AlH3 one of most promising hydrogen storage media for mobile application.This review covers the research activity on the structures,synthesis,decomposition thermodynamics and kinetics,regeneration and application validation of AlH3 over the past decades.Finally,the future research directions of AlH3 as a hydrogen storage material will be revealed.Haizhen Liu Longfei Zhang Hongyu Ma Chenglin Lu Hui Luo Xinhua Wang Xiantun Huang Zhiqiang Lan Jin Guo 2021Journal of Energy Chemistry2021,30,1:2
14Structures and Antiviral Activities of Butyrolactone Derivatives Isolated from Aspergillus terreus MXH-23显示文摘A new butyrolactone derivative, namely butyrolactone VIII(1), and six known butyrolactones(2-7) were separated from the ethyl acetate(Et OAc) extract of the fermentation broth of a fungus, Aspergillus terreus MXH-23. The chemical structures of these metabolites were identified by analyzing their nuclear magnetic resonance(NMR) and mass spectrometry(MS). Known butyrolactone derivatives contain an α,β-unsaturated γ-lactone ring with α-hydroxyl and γ-benzyl, and butyrolactone VIII(1) was the first butyrolactones contains α-benzyl and γ-hydroxyl on α,β-unsaturated lactone ring. All of the butyrolactone derivatives were tested for their anti-influenza(H1N1) effects. Derivatives 4 and 7 showed moderate antiviral activities while the newly-identified, derivative 1, did not.MA Xinhua ZHU Tianjiao GU Qianqun XI Rui WANG Wei LI Dehai 2014Journal of Ocean University of China2014,13,6:2
15“Extreme utilization”development of deep shale gas in southern Sichuan Basin,SW China显示文摘To efficiently develop deep shale gas in southern Sichuan Basin,under the guidance of“extreme utilization”theory,a basic idea and solutions for deep shale gas development are put forward and applied in practice.In view of multiple influencing factors of shale gas development,low single-well production and marginal profit of wells in this region,the basic idea is to establish“transparent geological body”of the block in concern,evaluate the factors affecting shale gas development through integrated geological-engineering research and optimize the shale gas development of wells in their whole life cycle to balance the relationship between production objectives and development costs.The solutions are as follows:(1)calculate the gold target index and pinpoint the location of horizontal well drilling target,and shale reservoirs are depicted accurately by geophysical and other means to build underground transparent geological body;(2)optimize the drilling and completion process,improve the adaptability of key tools by cooling,reducing density and optimizing the performance of drilling fluid,the“man-made gas reservoir”is built by comprehensively considering the characteristics of in-situ stress and fractures after the development well is drilled;(3)through efficient management,establishment of learning curve and optimization of drainage and production regime,the development quality and efficiency of the well are improved across its whole life cycle,to fulfil“extreme utilization”development of shale gas.The practice shows that the estimated ultimate recovery of single wells in southern Sichuan Basin increase by 10%-20%than last year.MA Xinhua WANG Hongyan ZHAO Qun LIU Yong ZHOU Shangwen HU Zhiming XIAO Yufeng 2022Petroleum Exploration and Development2022,49,6:2
16Biomarkers of aging显示文摘Aging biomarkers are a combination of biological parameters to(i)assess age-related changes,(ii)track the physiological aging process,and(iii)predict the transition into a pathological status.Although a broad spectrum of aging biomarkers has been developed,their potential uses and limitations remain poorly characterized.An immediate goal of biomarkers is to help us answer the following three fundamental questions in aging research:How old are we?Why do we get old?And how can we age slower?This review aims to address this need.Here,we summarize our current knowledge of biomarkers developed for cellular,organ,and organismal levels of aging,comprising six pillars:physiological characteristics,medical imaging,histological features,cellular alterations,molecular changes,and secretory factors.To fulfill all these requisites,we propose that aging biomarkers should qualify for being specific,systemic,and clinically relevant.Aging Biomarker Consortium Hainan Bao Jiani Cao Mengting Chen Min Chen Wei Chen Xiao Chen Yanhao Chen Yu Chen Yutian Chen Zhiyang Chen Jagadish K Chhetri Yingjie Ding Junlin Feng Jun Guo Mengmeng Guo Chuting He Yujuan Jia Haiping Jiang Ying Jing Dingfeng Li Jiaming Li Jingyi Li Qinhao Liang Rui Liang Feng Liu Xiaoqian Liu Zuojun Liu Oscar Junhong Luo Jianwei Lv Jingyi Ma Kehang Mao Jiawei Nie Xinhua Qiao Xinpei Sun Xiaoqiang Tang Jianfang Wang Qiaoran Wang Siyuan Wang Xuan Wang Yaning Wang Yuhan Wang Rimo Wu Kai Xia Fu-Hui Xiao Lingyan Xu Yingying Xu Haoteng Yan Liang Yang Ruici Yang Yuanxin Yang Yilin Ying Le Zhang Weiwei Zhang Wenwan Zhang Xing Zhang Zhuo Zhang Min Zhou Rui Zhou Qingchen Zhu Zhengmao Zhu Feng Cao Zhongwei Cao Piu Chan Chang Chen Guobing Chen Hou-Zao Chen Jun Chen Weimin Ci Bi-Sen Ding Qiurong Ding Feng Gao Jing-Dong JHan Kai Huang Zhenyu Ju Qing-Peng Kong Ji Li Jian Li Xin Li Baohua Liu Feng Liu Lin Liu Qiang Liu Qiang Liu Xingguo Liu Yong Liu Xianghang Luo Shuai Ma Xinran Ma Zhiyong Mao Jing Nie Yaojin Peng Jing Qu Jie Ren Ruibao Ren Moshi Song Zhou Songyang Yi Eve Sun Yu Sun Mei Tian Shusen Wang Si Wang Xia Wang Xiaoning Wang Yan-Jiang Wang Yunfang Wang Catherine CL Wong Andy Peng Xiang Yichuan Xiao Zhengwei Xie Daichao Xu Jing Ye Rui Yue Cuntai Zhang Hongbo Zhang Liang Zhang Weiqi Zhang Yong Zhang Yun-Wu Zhang Zhuohua Zhang Tongbiao Zhao Yuzheng Zhao Dahai Zhu Weiguo Zou Gang Pei Guang-Hui Liu 2023Science China(Life Sciences)2023,66,5:2
17Apple grading method based on neural network with ordered partitions and evidential ensemble learning显示文摘In order to improve the performance of the automatic apple grading and sorting system,in this paper,an ensemble model of ordinal classification based on neural network with ordered partitions and Dempster–Shafer theory is proposed.As a non-destructive grading method,apples are graded into three grades based on the Soluble Solids Content value,with features extracted from the preprocessed near-infrared spectrum of apple serving as model inputs.Considering the uncertainty in grading labels,mass generation approach and evidential encoding scheme for ordinal label are proposed,with uncertainty handled within the framework of Dempster–Shafer theory.Constructing neural network with ordered partitions as the base learner,the learning procedure of the Bagging-based ensemble model is detailed.Experiments on Yantai Red Fuji apples demonstrate the satisfactory grading performances of proposed evidential ensemble model for ordinal classification.Liyao Ma Peng Wei Xinhua Qu Shuhui Bi Yuan Zhou Tao Shen 2022CAAI Transactions on Intelligence Technology2022,7,4:1
18Genomic Epidemiology of Carbapenemaseproducing Klebsiella pneumoniae in China显示文摘The rapid spread of carbapenemase-producing Klebsiella pneumoniae(cpKP)poses serious threats to public health;however,the underlying genetic basis for its dissemination is still unknown.We conducted a comprehensive genomic epidemiology analysis on 420 cpKP isolates collected from 70 hospitals in 24 provinces/autonomous regions/municipalities of China during 2009–2017 by short-/long-read sequencing.The results showed that most cpKP isolates were categorized into clonal group 258(CG258),in which ST11 was the dominant clone.Phylogenetic analysis revealed three major clades including the top one of Clade 3 for CG258 cpKP isolates.Additionally,carbapenemase gene analysis indicated that blaKPC was dominant in the cpKP isolates,and most blaKPC genes were located in five major incompatibility(Inc)groups of blaKPC-harboring plasmids.Importantly,three advantageous combinations of host–blaKPC-carrying plasmid(Clade 3.1+3.2–IncFIIpHN7A8,Clade 3.1+3.2–IncFIIpHN7A8:IncR,and Clade 3.3–IncFIIpHN7A8:IncpA1763-KPC)were identified to confer cpKP isolates the advantages in both genotypes(strong correlation/coevolution)and phenotypes(resistance/growth/competition)to facilitate the nationwide spread of ST11/CG258 cpKP.Intriguingly,Bayesian skyline analysis illustrated that the three advantageous combinations might be directly associated with the strong population expansion during 2007–2008 and subsequent maintenance of the population of ST11/CG258 cpKP after 2008.We then examined drug resistance profiles of these cpKP isolates and proposed combination treatment regimens for CG258/non-CG258 cpKP infections.Thus,the findings of our systematical analysis shed light on the molecular epidemiology and genetic basis for the dissemination of ST11/CG258 cpKP in China,and much emphasis should be given to the close monitoring of advantageous cpKP–plasmid combinations.Cuidan Li Xiaoyuan Jiang Tingting Yang Yingjiao Ju Zhe Yin Liya Yue Guannan Ma Xuebing Wang Ying Jing Xinhua Luo Shuangshuang Li Xue Yang Fei Chen Dongsheng Zhou 2022Genomics, Proteomics & Bioinformatics2022,20,6:1
19Phenylspirodimanes with Anti - HIV Activity from the SongeDerived Fungus Stachybotrys chartarum MXH - X73 显示文摘Xinhua Ma 2013Natural Products2013,,:1
20Low Temperature PlasmaInitiated Precipitation Copolymerization of Styrene and Maleic Anhydride显示文摘Da Yan Xinhua Xu Guiqiu Ma 2012Journal of Applied Polymer Science2012,89,:1
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