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| 1 | Divergent Projection Patterns Revealed by Reconstruction of Individual Neurons in Orbitofrontal Cortex显示文摘The orbitofrontal cortex(OFC)is involved in diverse brain functions via its extensive projections to multiple target regions.There is a growing understanding of the overall outputs of the OFC at the population level,but reports of the projection patterns of individual OFC neurons across different cortical layers remain rare.Here,by combining neuronal sparse and bright labeling with a whole-brain florescence imaging system(fMOST),we obtained an uninterrupted three-dimensional whole-brain dataset and achieved the full morphological reconstruction of 25 OFC pyramidal neurons.We compared the wholebrain projection targets of these individual OFC neurons in different cortical layers as well as in the same cortical layer.We found cortical layer-dependent projections characterized by divergent patterns for information delivery.Our study not only provides a structural basis for understanding the principles of laminar organizations in the OFC,but also provides clues for future functional and behavioral studies on OFC pyramidal neurons. | Junjun Wang Pei Sun Xiaohua Lv Sen Jin Anan Li Jianxia Kuang Ning Li Yadong Gang Rui Guo Shaoqun Zeng Fuqiang Xu Yu-Hui Zhang | 2021 | Neuroscience Bulletin2021，37，4： | 5 |
| 2 | Origin and Classification of Geothermal Water from Guanzhong Basin,NW China:Geochemical and Isotopic Approach显示文摘Combined with tectonic evolution,a multi-isotopic method(δD,δ18O,87Sr/86Sr and 14C)and hydrochemistry data have been used to study the origin and classification of geothermal water in the Guanzhong Basin.The study shows that geothermal water of Xianli terrace primarily came from northwest direction when accepting recharge.A small amount supply source of geothermal water in Xi’an City is from Qinling Mountain and the principal supply source comes from the west direction,but geothermal water of Chang’an District mainly accepts supply from Qinling Mountain.Based on geothermal environment is open or not,the degree of water-rock interaction,and the origin of geothermal water,geothermal water of the study area can be divided into four types:A,geothermal water of Gushi depression,perfect closed thermal environment and significant water-rock interaction,belonged to residual sedimentary water origin;B,geothermal water of Xianyang City,good closed environment and relatively significant water-rock interaction,belonged to residual sedimentary water origin mixed with fossil leaching water;C,geothermal water of Xi’an City,half closed environment and some water-rock interaction,belonged to fossil leaching water origin;D,geothermal water of Chang’an District,open environment and mixed with modern precipitation,belonged to fossil leaching water origin. | Zhiyuan Ma Xiucheng Li Huiju Zheng Jingbin Li Bei Pei Sen Guo Xuelian Zhang | 2017 | Journal of Earth Science2017，28，4： | 4 |
| 3 | Rapid and Sparse Labeling of Neurons Based on the Mutant Virus-Like Particle of Semliki Forest Virus显示文摘Sparse labeling of neurons contributes to uncovering their morphology, and rapid expression of a fluorescent protein reduces the experiment range. To achieve the goal of rapid and sparse labeling of neurons in vivo, we established a rapid method for depicting the fine structure of neurons at 24 h post-infection based on a mutant viruslike particle of Semliki Forest virus. Approximately 0.014 fluorescent focus-forming units of the mutant virus-like particle transferred enhanced green fluorescent protein into neurons in vivo, and its affinity for neurons in vivo was stronger than for neurons in vitro and BHK21(baby hamster kidney) cells. Collectively, the mutant virus-likeparticle provides a robust and convenient way to reveal the fine structure of neurons and is expected to be a helper virus for combining with other tools to determine their connectivity. Our work adds a new tool to the approaches for rapid and sparse labeling of neurons in vivo. | Fan Jia Xutao Zhu Pei Lv Liang Hu Qing Liu Sen Jin Fuqiang Xu | 2019 | Neuroscience Bulletin2019，35，3： | 3 |
| 4 | A Study of the Key Techniques of High-Speed Optical Time Division Multiplexing Systems显示文摘 | LIU Xian bing directed by YE Pei da, ZHAO Zi sen | 2001 | The Journal of China Universities of Posts and Telecommunications2001，8，4： | 1 |
| 5 | An reproved LiftingMor- phologieal Wavelet Method and Its Application in Power Quality Dis- turbances Detection 显示文摘 | WEN Zhuowen OOYANG Sen PEI Haoju | 2012 | IEEE Transactions on Power Delivery2012，，： | 1 |
| 6 | Preparation of Electrospun PLGA-silk Fibroin Nanofibers-based Nerve Conduits and Evaluation In Vivo显示文摘 | Sen Li Hui Wu Xu-Dong Hu Chong-Qi Tu Fu-Xing Pei Guang-Lin Wang Wei Lin Hong-Song Fan | 2012 | Artificial Cells, Blood Substitutes and Biotechnology . 2012 (1-2)2012，，1： | 1 |
| 7 | Association between adverse clinical outcome in human disease caused by novel influenza A H7N9 virus and sustained viral shedding and emergence of antiviral resistance显示文摘 | Yunwen Hu Shuihua Lu Zhigang Song Wei Wang Pei Hao Jianhua Li Xiaonan Zhang Hui-Ling Yen Bisheng Shi Tao Li Wencai Guan Lei Xu Yi Liu Sen Wang Xiaoling Zhang Di Tian Zhaoqin Zhu Jing He Kai Huang Huijie Chen Lulu Zheng Xuan Li Jie Ping Bin Kang Xiuhong Xi | 2013 | The Lancet2013，，9885： | 1 |
| 8 | Divergent responses of soil carbon and nitrogen pools to short-term nitrogen addition between two plantations in Northeast China显示文摘Nitrogen(N)deposition has a profound influence on forest soil carbon(C)and N pools,but there was no consensus on the responses of different C and N components in different forest types.In this study,a two-year simulated N deposition experiment with four levels of N(NH4NO3)-addition treatments(0,50,100,and 150 kg N/hm^(2)·a)were conducted in Larix gmelinii(LG)and Quercus mongolica(QM)plantation in Northeast China,in order to investigate the C and N pool dynamics under continuously enhanced N deposition.Soil organic carbon(SOC),soil total N(STN)and their active components(readily oxidizable C,ROC;dissolved organic C,DOC;microbial biomass C,MBC,dissolved organic N,DON;microbial biomass N,MBN)of the forest soil were measured monthly from May to October 2017.C and N contents in LG were observed higher than in QM.N addition had no effect on SOC and STN of LG,but significantly increased SOC and STN of QM at low N addition level.Low N addition generally raised active C components(ROC,DOC,and MBC)in both plantations,whereas high N addition did not significantly affect these components,or even decreased ROC in LG soil.Low N addition also increased STN and MBN of QM,while no significant change in STN and MBN of LG was observed.DON was directly affected by N addition and increased significantly with elevated N addition levels.The results indicated that N addition,especially of low rate,might enhance the C sequestration capacity of the forest soils and mitigate climate change. | Yedong Li Bo Wang Sen Dou Haoyue Shen Liyong Mei Yang Zhang Ximing Zeng Yaya Zhang Yameng Pei Haoye Ren Shimin Wu | 2019 | International Journal of Agricultural and Biological Engineering2019，12，6： | 1 |
| 9 | A Survey of Urolithiasis in Young Children Fed Infant Formula Contaminated with Melamine in Two Townships of Gansu,China显示文摘Objective To determine the prevalence of urolithiasis in young children fed infant formula(IF) contaminated with melamine,and the association between IF consumption and urolithiasis.Design A total of 2 733 children ≤3 years of age on September 1,2008 in two townships of Gansu Province,China were studied.Cases of urolithiasis were diagnosed by ultrasonography.Milk product consumption was determined by their caregivers.Remaining IF samples were tested for melamine and cyanuric acid.Results Of 2 733 eligible children in the two townships,2 186(80%) were enrolled in our study.Overall,16.6%(362) of 2 186 children had urolithiasis.The prevalence was 24.6% in children exclusively fed Sanlu brand IF,9.7% in those fed other IF,and 8.5% in those fed exclusively on other milk products.For children exclusively breast-fed,no urolithiasis was found(P<0.05).The prevalence of urolithiasis was 11.4% in children fed 400 g of Sanlu IF,rising to 37.5% in children fed over 25 600 g.Of 48 Sanlu IF samples,91.7% contained melamine(median=1 800 ppm;range=45-4 700) and 66.7% contained cyanuric acid(median=1.2 ppm;range=0.4-6.3).Melamine was also detected in 22.2% of 36 other brand IF(median=27.5 ppm,range=4-50).Conclusions Urolithiasis was associated with melamine-contaminated IF.Although one product caused most morbidity,other milk products may have also contributed to the outbreak. | SHI Guo Qing WANG Zi Jun FENG Zi Jian GAO Yong Jun LIU Jian Di SHEN Tao LIMing YANG Jin XU Hai Bing JIANG Xiao Hong WANG Zhao Nan CAI Mei WANG Yu Min ZHU Ye Fan LIU Hui Hui WANG Rui XIONG Wei Yi WANG Zhu Tian YANG Wei Zhong HOU Pei Sen ZENG Guang WANG Yu | 2012 | Biomedical and Environmental Sciences2012，25，2： | 1 |
| 10 | Surgical treatment for uncinate process carcinoma of the pancreas显示文摘Objectives: To analyze the clinical features of unci-nate process carcinoma of the pancreas and to im-prove the resection rate.Methods: From January 1990 to June 1999, 10 pa-tients with pancreas uncinate process carcinoma re-ceived Whipple’s operation. Portal vein (PV) resec-tion and reanastomosis were performed in 5 patients,and the resected length varied from 2.0 to 4.2 cm.Two patients underwent PV lateral wall partial resec-tion.Results: Among the 7 patients undergoing PV resec-tion, 1 died of hepatic failure 3 days after operation.One patient suffered from postoperative chylous asci-tes. These 6 patients survived 13 to 29 months post-operatively. Among the 3 patients without PV resec-tion, 2 survived 13 months and 14 months respective-ly. One patient was alive by the end of follow-up for11. 5 months postoperatively.Conclusion: Although uncinate process carcinoma ofthe pancreas has a tendency to invade the adjacent PVand superior mesentery vein, it should not be simplyregarded as a contraindication of radical resection. | Sen Li Yong-Quan Pei Fu-Tian Du Guan-Yi Zhuang Chun-You Li Qin-Hua Song Wei Ding Jian-Li Wang the Department of Hepatobiliary Surgery, Weifang People’s Hospital, Weifang 261041, China | 2002 | Hepatobiliary & Pancreatic Diseases International2002，1，4： | 1 |
| 11 | Extended local resection for treatment of periampullary carcinoma of vater显示文摘BACKGROUND: The trauma caused by pancreatoduode- nectomy for periampullary carcinoma of vater is often se- vere and extensive. The purpose of this study was to eva- luate the effect of extended local resection in the treatment of periampullary carcinoma of vater. METHODS: The extra-hepaticobiliary tract, the confluence of the pancreatic and biliary duct, vater ampulla and duo- denal papilla were resected en bloc in 8 patients with peri- ampullary carcinoma from 1995 to 1998. RESULTS: One patient died perioperatively. Duodenal ob- struction developed postoperatively in one of 7 survived pa- tients and was relieved after reoperation. All the 7 patients were followed up for more than 6 months without recur- rence. CONCLUSION: Extended local resection fulfils the task of radical treatment of periampullary malignancy. | Sen Li, Guan-Yi Zhuang, Yong-Quan Pei,Chun-You Li, Jian-Li Wang, Wei Ding, Fu-Tian Du, Qin-Hua Song and Kai-Xiang Lin Weifang, China Department of Hepatobiliary Surgery, Weifang Peo- ple ’s Hospital, Weifang 261041 , China | 2004 | Hepatobiliary & Pancreatic Diseases International2004，3，2： | 1 |
| 12 | Searching for supersprea- ders of information in real-world social media 显示文摘 | Pei Sen Muchnik L Andrade J S | 2014 | Scientific Re- ports2014，4，00： | 1 |
| 13 | Weighted Poineare - type Inequalities for Differential Forms in L^1(μ)- averaging Domain显示文摘 | Ding Shu -sen Shi Pei - lin | 1998 | J Math Anal Appl1998，227，： | 1 |
| 14 | Association between adverse clinical outcome in human disease caused by novel influenza A H7N9 virus and sustained viral shedding and emergence of antiviral resistance显示文摘 | Yunwen Hu Shuihua Lu Zhigang Song Wei Wang Pei Hao Jianhua Li Xiaonan Zhang Hui-Ling Yen Bisheng Shi Tao Li Wencai Guan Lei Xu Yi Liu Sen Wang Xiaoling Zhang Di Tian Zhaoqin Zhu Jing He Kai Huang Huijie Chen Lulu Zheng Xuan Li Jie Ping Bin Kang Xiuhong Xi | 2013 | The Lancet2013，，9885： | 1 |
| 15 | Feasibility and physics potential of detecting ^(8)B solar neutrinos at JUNO显示文摘The Jiangmen Underground Neutrino Observatory(JUNO)features a 20 kt multi-purpose underground liquid scintillator sphere as its main detector.Some of JUNO's features make it an excellent location for^8B solar neutrino measurements,such as its low-energy threshold,high energy resolution compared with water Cherenkov detectors,and much larger target mass compared with previous liquid scintillator detectors.In this paper,we present a comprehensive assessment of JUNO's potential for detecting^8B solar neutrinos via the neutrino-electron elastic scattering process.A reduced 2 MeV threshold for the recoil electron energy is found to be achievable,assuming that the intrinsic radioactive background^(238)U and^(232)Th in the liquid scintillator can be controlled to 10^(-17)g/g.With ten years of data acquisition,approximately 60,000 signal and 30,000 background events are expected.This large sample will enable an examination of the distortion of the recoil electron spectrum that is dominated by the neutrino flavor transformation in the dense solar matter,which will shed new light on the inconsistency between the measured electron spectra and the predictions of the standard three-flavor neutrino oscillation framework.IfDelta m^(2)_(21)=4.8times10^(-5);(7.5times10^(-5))eV^(2),JUNO can provide evidence of neutrino oscillation in the Earth at approximately the 3sigma(2sigma)level by measuring the non-zero signal rate variation with respect to the solar zenith angle.Moreover,JUNO can simultaneously measureDelta m^2_(21)using^8B solar neutrinos to a precision of 20% or better,depending on the central value,and to sub-percent precision using reactor antineutrinos.A comparison of these two measurements from the same detector will help understand the current mild inconsistency between the value of Delta m^2_(21)reported by solar neutrino experiments and the KamLAND experiment. | Angel Abusleme Thomas Adam Shakeel Ahmad Sebastiano Aiello Muhammad Akram Nawab Ali Fengpeng An Guangpeng An Qi An Giuseppe Andronico Nikolay Anfimov Vito Antonelli Tatiana Antoshkina Burin Asavapibhop João Pedro Athayde Marcondes de André Didier Auguste Andrej Babic Wander Baldini Andrea Barresi Eric Baussan Marco Bellato Antonio Bergnoli Enrico Bernieri David Biare Thilo Birkenfeld Sylvie Blin David Blum Simon Blyth Anastasia Bolshakova Mathieu Bongrand Clément Bordereau Dominique Breton Augusto Brigatti Riccardo Brugnera Riccardo Bruno Antonio Budano Max Buesken Mario Buscemi Jose Busto Ilya Butorov Anatael Cabrera Hao Cai Xiao Cai Yanke Cai Zhiyan Cai Antonio Cammi Agustin Campeny Chuanya Cao Guofu Cao Jun Cao Rossella Caruso Cédric Cerna Jinfan Chang Yun Chang Pingping Chen Po-An Chen Shaomin Chen Shenjian Chen Xurong Chen Yi-Wen Chen Yixue Chen Yu Chen Zhang Chen Jie Cheng Yaping Cheng Alexander Chepurnov Davide Chiesa Pietro Chimenti Artem Chukanov Anna Chuvashova Gérard Claverie Catia Clementi Barbara Clerbaux Selma Conforti Di Lorenzo Daniele Corti Salvatore Costa Flavio Dal Corso Christophe De La Taille Jiawei Deng Zhi Deng Ziyan Deng Wilfried Depnering Marco Diaz Xuefeng Ding Yayun Ding Bayu Dirgantara Sergey Dmitrievsky Tadeas Dohnal Georgy Donchenko Jianmeng Dong Damien Dornic Evgeny Doroshkevich Marcos Dracos Frédéric Druillole Shuxian Du Stefano Dusini Martin Dvorak Timo Enqvist Heike Enzmann Andrea Fabbri Lukas Fajt Donghua Fan Lei Fan Can Fang Jian Fang Marco Fargetta Anna Fatkina Dmitry Fedoseev Vladko Fekete Li-Cheng Feng Qichun Feng Richard Ford Andrey Formozov Amélie Fournier Haonan Gan Feng Gao Alberto Garfagnini Alexandre Göttel Christoph Genster Marco Giammarchi Agnese Giaz Nunzio Giudice Franco Giuliani Maxim Gonchar Guanghua Gong Hui Gong Oleg Gorchakov Yuri Gornushkin Marco Grassi Christian Grewing Maxim Gromov Vasily Gromov Minghao Gu Xiaofei Gu Yu Gu Mengyun Guan Nunzio Guardone Maria Gul Cong Guo Jingyuan Guo Wanlei Guo Xinheng Guo Yuhang Guo Paul Hackspacher Caren Hagner Ran Han Yang Han Miao He Wei He Tobias Heinz Patrick Hellmuth Yuekun Heng Rafael Herrera Daojin Hong YuenKeung Hor Shaojing Hou Yee Hsiung Bei-Zhen Hu Hang Hu Jianrun Hu Jun Hu Shouyang Hu Tao Hu Zhuojun Hu Chunhao Huang Guihong Huang Hanxiong Huang Qinhua Huang Wenhao Huang Xingtao Huang Yongbo Huang Jiaqi Hui Wenju Huo Cédric Huss Safeer Hussain Antonio Insolia Ara Ioannisian Daniel Ioannisyan Roberto Isocrate Kuo-Lun Jen Xiaolu Ji Xingzhao Ji Huihui Jia Junji Jia Siyu Jian Di Jiang Xiaoshan Jiang Ruyi Jin Xiaoping Jing Cécile Jollet Jari Joutsenvaara Sirichok Jungthawan Leonidas Kalousis Philipp Kampmann Li Kang Michael Karagounis Narine Kazarian Amir Khan Waseem Khan Khanchai Khosonthongkee Patrick Kinz Denis Korablev Konstantin Kouzakov Alexey Krasnoperov Svetlana Krokhaleva Zinovy Krumshteyn Andre Kruth Nikolay Kutovskiy Pasi Kuusiniemi Tobias Lachenmaier Cecilia Landini Sébastien Leblanc Frederic Lefevre Liping Lei Ruiting Lei Rupert Leitner Jason Leung Demin Li Fei Li Fule Li Haitao Li Huiling Li Jiaqi Li Jin Li Kaijie Li Mengzhao Li Nan Li Nan Li Qingjiang Li Ruhui Li Shanfeng Li Shuaijie Li Tao Li Weidong Li Weiguo Li Xiaomei Li Xiaonan Li Xinglong Li Yi Li Yufeng Li Zhibing Li Ziyuan Li Hao Liang Hao Liang Jingjing Liang Jiajun Liao Daniel Liebau Ayut Limphirat Sukit Limpijumnong Guey-Lin Lin Shengxin Lin Tao Lin Jiajie Ling Ivano Lippi Fang Liu Haidong Liu Hongbang Liu Hongjuan Liu Hongtao Liu Hu Liu Hui Liu Jianglai Liu Jinchang Liu Min Liu Qian Liu Qin Liu Runxuan Liu Shuangyu Liu Shubin Liu Shulin Liu Xiaowei Liu Yan Liu Alexey Lokhov Paolo Lombardi Claudio Lombardo Kai Loo Chuan Lu Haoqi Lu Jingbin Lu Junguang Lu Shuxiang Lu Xiaoxu Lu Bayarto Lubsandorzhiev Sultim Lubsandorzhiev Livia Ludhova Fengjiao Luo Guang Luo Pengwei Luo Shu Luo Wuming Luo Vladimir Lyashuk Qiumei Ma Si Ma Xiaoyan Ma Xubo Ma Jihane Maalmi Yury Malyshkin Fabio Mantovani Francesco Manzali Xin Mao Yajun Mao Stefano MMari Filippo Marini Sadia Marium Cristina Martellini Gisele Martin-Chassard Agnese Martini Davit Mayilyan Axel Müller Ints Mednieks Yue Meng Anselmo Meregaglia Emanuela Meroni David Meyhöfer Mauro Mezzetto Jonathan Miller Lino Miramonti Salvatore Monforte Paolo Montini Michele Montuschi Nikolay Morozov Pavithra Muralidharan Massimiliano Nastasi Dmitry VNaumov Elena Naumova Igor Nemchenok Alexey Nikolaev Feipeng Ning Zhe Ning Hiroshi Nunokawa Lothar Oberauer Juan Pedro Ochoa-Ricoux Alexander Olshevskiy Domizia Orestano Fausto Ortica Hsiao-Ru Pan Alessandro Paoloni Nina Parkalian Sergio Parmeggiano Teerapat Payupol Yatian Pei Nicomede Pelliccia Anguo Peng Haiping Peng Frédéric Perrot Pierre-Alexandre Petitjean Fabrizio Petrucci Luis Felipe Piñeres Rico Oliver Pilarczyk Artyom Popov Pascal Poussot Wathan Pratumwan Ezio Previtali Fazhi Qi Ming Qi Sen Qian Xiaohui Qian Hao Qiao Zhonghua Qin Shoukang Qiu Muhammad Rajput Gioacchino Ranucci Neill Raper Alessandra Re Henning Rebber Abdel Rebii Bin Ren Jie Ren Taras Rezinko Barbara Ricci Markus Robens Mathieu Roche Narongkiat Rodphai Aldo Romani Bedřich Roskovec Christian Roth Xiangdong Ruan Xichao Ruan Saroj Rujirawat Arseniy Rybnikov Andrey Sadovsky Paolo Saggese Giuseppe Salamanna Simone Sanfilippo Anut Sangka Nuanwan Sanguansak Utane Sawangwit Julia Sawatzki Fatma Sawy Michaela Schever Jacky Schuler Cédric Schwab Konstantin Schweizer Dmitry Selivanov Alexandr Selyunin Andrea Serafini Giulio Settanta Mariangela Settimo Muhammad Shahzad Vladislav Sharov Gang Shi Jingyan Shi Yongjiu Shi Vitaly Shutov Andrey Sidorenkov FedorŠimkovic Chiara Sirignano Jaruchit Siripak Monica Sisti Maciej Slupecki Mikhail Smirnov Oleg Smirnov Thiago Sogo-Bezerra Julanan Songwadhana Boonrucksar Soonthornthum Albert Sotnikov Ondrej Sramek Warintorn Sreethawong Achim Stahl Luca Stanco Konstantin Stankevich DušanŠtefánik Hans Steiger Jochen Steinmann Tobias Sterr Matthias Raphael Stock Virginia Strati Alexander Studenikin Gongxing Sun Shifeng Sun Xilei Sun Yongjie Sun Yongzhao Sun Narumon Suwonjandee Michal Szelezniak Jian Tang Qiang Tang Quan Tang Xiao Tang Alexander Tietzsch Igor Tkachev Tomas Tmej Konstantin Treskov Andrea Triossi Giancarlo Troni Wladyslaw Trzaska Cristina Tuve Stefan van Waasen Johannes van den Boom Guillaume Vanroyen Nikolaos Vassilopoulos Vadim Vedin Giuseppe Verde Maxim Vialkov Benoit Viaud Cristina Volpe Vit Vorobel Lucia Votano Pablo Walker Caishen Wang Chung-Hsiang Wang En Wang Guoli Wang Jian Wang Jun Wang Kunyu Wang Lu Wang Meifen Wang Meng Wang Ruiguang Wang Siguang Wang Wei Wang Wenshuai Wang Xi Wang Xiangyue Wang Yangfu Wang Yaoguang Wang Yi Wang Yifang Wang Yuanqing Wang Yuman Wang Zhe Wang Zheng Wang Zhimin Wang Zongyi Wang Apimook Watcharangkool Lianghong Wei Wei Wei Yadong Wei Liangjian Wen Christopher Wiebusch Steven Chan-Fai Wong Bjoern Wonsak Diru Wu Fangliang Wu Qun Wu Wenjie Wu Zhi Wu Michael Wurm Jacques Wurtz Christian Wysotzki Yufei Xi Dongmei Xia Yuguang Xie Zhangquan Xie Zhizhong Xing Benda Xu Donglian Xu Fanrong Xu Jilei Xu Jing Xu Meihang Xu Yin Xu Yu Xu Baojun Yan Xiongbo Yan Yupeng Yan Anbo Yang Changgen Yang Huan Yang Jie Yang Lei Yang Xiaoyu Yang Yifan Yang Haifeng Yao Zafar Yasin Jiaxuan Ye Mei Ye Ugur Yegin Frédéric Yermia Peihuai Yi Xiangwei Yin Zhengyun You Boxiang Yu Chiye Yu Chunxu Yu Hongzhao Yu Miao Yu Xianghui Yu Zeyuan Yu Chengzhuo Yuan Ying Yuan Zhenxiong Yuan Ziyi Yuan Baobiao Yue Noman Zafar Andre Zambanini Pan Zeng Shan Zeng Tingxuan Zeng Yuda Zeng Liang Zhan Feiyang Zhang Guoqing Zhang Haiqiong Zhang Honghao Zhang Jiawen Zhang Jie Zhang Jingbo Zhang Peng Zhang Qingmin Zhang Shiqi Zhang Tao Zhang Xiaomei Zhang Xuantong Zhang Yan Zhang Yinhong Zhang Yiyu Zhang Yongpeng Zhang Yuanyuan Zhang Yumei Zhang Zhenyu Zhang Zhijian Zhang Fengyi Zhao Jie Zhao Rong Zhao Shujun Zhao Tianchi Zhao Dongqin Zheng Hua Zheng Minshan Zheng Yangheng Zheng Weirong Zhong Jing Zhou Li Zhou Nan Zhou Shun Zhou Xiang Zhou Jiang Zhu Kejun Zhu Honglin Zhuang Liang Zong Jiaheng Zou | 2021 | Chinese Physics C2021，45，2： | 0 |
| 16 | Biotransformation of quinoa phenolic compounds with Monascus anka to enhance the antioxidant capacity and digestive enzyme inhibitory activity显示文摘This research aims to change the phenolic fractions and the bioactivities of quinoa by solid-state fermentation(SSF)with the edible fungus Monascus anka(M.anka).The contents of protein and fat increased in the fermented product,while the carbohydrate decreased.After 6-day fermentation with M.anka,the amount of phenolic compound reached the highest level.The majority of phenolic forms in fermented quinoa were phenolic acids,mainly ferulic acid,protocatechuic acid and p-hydroxybenzoic acid.Ultrahigh-performance liquid chromatography-mass spectrometry(UHPLC-MS)results showed that SSF was an effective method to transform quinoa phenolic compounds.Free fractions could be rapidly absorbed in the small intestine,suggesting that SSF with M.anka was a useful method to enhance bioavailable antioxidants.Antioxidant ability in vitro results showed that phenolic fractions from fermented quinoa were greater than the unfermented quinoa,and a significant cellular antioxidant activity(CAA)increment of 135%was obtained in the free phenolic fraction of fermented quinoa.Moreover,α-amylase andα-glucosidase inhibition activities were enhanced with fermentation.Correlation matrix analysis revealed that most of the free phenolic compounds showed strong positive correlations with antioxidant activities and digestive enzyme activities.Consequently,fermentation with M.anka was a particularly promising method to enhance the bioactivity of quinoa. | Pei Yang Kai Huang Yu Zhang Sen Li Hongwei Cao Hongdong Song Ying Zhang Xiao Guan | 2022 | Food Bioscience2022，46，2： | 0 |
| 17 | Assessing the spread risk of COVID-19 associated with multi-mode transportation networks in China显示文摘The spatial spread of COVID-19 during early 2020 in China was primarily driven by outbound travelers leaving the epicenter,Wuhan,Hubei province.Existing studies focus on the influence of aggregated out-bound population flows originating from Wuhan;however,the impacts of different modes of transportation and the network structure of transportation systems on the early spread of COVID-19 in China are not well understood.Here,we assess the roles of the road,railway,and air transportation networks in driving the spatial spread of COVID-19 in China.We find that the short-range spread within Hubei province was dominated by ground traffic,notably,the railway transportation.In contrast,long-range spread to cities in other provinces was mediated by multiple factors,including a higher risk of case importation associated with air transportation and a larger outbreak size in hub cities located at the center of transportation networks.We further show that,although the dissemination of SARS-CoV-2 across countries and continents is determined by the worldwide air transportation network,the early geographic dispersal of COVID-19 within China is better predicted by the railway traffic.Given the recent emergence of multiple more transmissible variants of SARS-CoV-2,our findings can support a better assessment of the spread risk of those variants and improve future pandemic preparedness and responses. | Xiao-Ke Xu Xiao Fan Liu Lin Wang Ye Wu Xin Lu Xianwen Wang Sen Pei | 2023 | Fundamental Research2023，3，2： | 0 |
| 18 | A nonprofiled side-channel analysis based on variational lower bound related to mutual information显示文摘In this paper,we attempt to improve the practical performance of the nonprofiled side-channel analysis(Non SCA)with the help of neural networks.We first derive a variational lower bound related to mutual information(VLBRMI)optimized for the context of Non SCA,which possesses a set of adjustable parameters and whose maximum value linearly depends on the mutual information.Then,we propose a new Non SCA method called neural mutual information analysis(NMIA)that exploits the maximum VLBRMI as the distinguisher.We present an estimator of the maximum VLBRMI,which uses neural networks to instantiate the VLBRMI and trains the neural networks to approximate the maximum VLBRMI so that we can implement the NMIA efficiently.Finally,we evaluate the NMIA on several datasets.The experimental results show that NMIA outperforms the correlation power analysis,the mutual information analysis(MIA)based on histograms,the MIA based on kernel density estimation,and the state-of-the-art Non SCA method based on neural networks. | Chi ZHANG Xiangjun LU Pei CAO Dawu GU Zheng GUO Sen XU | 2023 | Science China(Information Sciences)2023，66，1： | 0 |
| 19 | Peripheral Coordination-Dependent Descriptor for Selective Interactions between Near-Frontier Molecular Orbitals and Single-Atom Catalysts显示文摘Selective adsorption of α,β-unsaturated aldehydes(α,β-UALs)is a prerequisite for the hydrogenation of α,β-UALs to high-value unsaturated alcohols,but a quantitative description of the interactions between the C=C/C=O bond of α,β-UALs and the catalysts is still lacking.Herein,based on comprehensive density functional theory calculations,we developed a descriptor that combines the near-frontier molecular orbitals of the C=C/C=O bonds of α,β-UALs with the fundamental physical properties of single-atom catalysts(SACs)and considers the inner/outer coordination environment.All of the parameters used in this descriptor are easily accessible and interpretable,enabling an efficient assessment of the selectivity of SACs for the C=C/C=O bonds ofα,β-UALs. | Bingqing Ge Fenfei Wei Qiang Wan Hongwei Zhang Pei Yuan Sen Lin | 2023 | Precision Chemistry2023，1，7： | 0 |
| 20 | Abrupt decrease of c-myc expression by antisense transcripts induces terminal differentiation and apoptosis in human promyelocytic leukemia HL-60 cells显示文摘This study was designed using c-myc antisense transcripts to evaluate how alteration of c-myc expression in human myeloid leukemic HL-60 cells could influence the myelomonocytic differentiation and induction of apoptosis. The recombinant plasmid pDACx expressing antisense transcripts to c-myc fragment containing a part of intron 1 and 137 nt exon 2 was constructed. pDACx was transfected into HL-60 cell line by lipofectin reagent.Cytochemical stainings including NBT reduction, peroxidase and α -NAE as well as detection of CD13 and CD33 antigens by flow cytometric analysis indicated occurrence of myelomonocytic differentiation in cells expressing antisense transcripts to c-myc. DNA degradation measured by DNA gel electrophoresis and typical morphological changes observed under electron microscope proved the switchon of apoptosis in terminally differentiating HL-60 cells. | HAO XIU JUAN PEI HSIEN TANG XIU SEN LI FEI ZI JIANG YONG ZHI XI NING MAO DE LIN DU MIN WU (Institute of Basic Medical Sciences, Beijing 100850)(National Laboratory of Molecular Oncology, In stitute of Cancer Research Beijing, Chinese Academy of Med | 1996 | Cell Research1996，6，2： | 0 |
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