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| 1 | Ubiquitylation of p62/sequestosome1 activates its autophagy receptor function and controls selective autophagy upon ubiquitin stress显示文摘在细胞的 ubiquitin (Ub ) 的改变动态平衡,作为 Ub 知道强调,展示并且影响处于多重条件的细胞的回答,然而,内在的机制不完全地被理解。这里,我们报导 autophagy 受体 p62/sequestosome-1 与结合酶, UBE2D2 和 UBE2D3 的 E2 Ub 交往。内长的 p62 在 Ub 动态平衡的 upregulation 期间经历 E2 依赖的 ubiquitylation,一个条件作为 Ub + 应力称为,那对由 bortezomib 的 Ub overexpression,热吃惊或延长 proteasomal 抑制内在,化学疗法的药。p62 的 Ubiquitylation 破坏 p62 的 UBA 领域的 dimerization,解放它的能力认出为选择 autophagy 的 polyubiquitylated 货物。我们进一步证明这机制可能为在 Ub + 压力条件之上的 autophagy 激活是批评的。机制的描述和在察觉到 Ub 应力并且控制选择 autophagy 的 p62 的规章的角色能帮助理解并且调制细胞的回答到许多内长、环境的挑战,潜在地对 autophagy 相关的病为治疗学的策略的发展打开一条新大街。 | Hong Peng Jiao Yang Guangyi Li Qing You Wen Han Tianrang Li Darning Gao Xiaoduo Xie Byung-Hoon Lee Juan Du Jian Hou Tao Zhang Hai Rao Ying Huang Qinrun Li Rong Zeng Lijian Hui Hongyan Wang Qin Xia Xuemin Zhang Yongning He Masaaki Komatsu Ivan Dikic Daniel Finley Ronggui Hu | 2017 | Cell Research2017，27，5： | 9 |
| 2 | Temperature dependence of pyro-phototronic effect on self-powered ZnO/perovskite heterostructured photodetectors显示文摘自我动力的 ZnO/perovskite heterostructured 紫外(紫外) 光电探测器(PD ) 最近作为的一个有希望的解决方案基于 pyro-phototronic 效果被报导了精力有效, ultrafast 反应,和高效的紫外 PD。在这研究,自我动力的 ZnO/perovskite heterostructured PD 的察觉到相片的表演上的 pyro-phototronic 效果的温度依赖被调查。到紫外光的这些 PD 的当前的回答被 174.1% 在 77 K 提高, 28.7% 在低温度在由于改进 pyro-phototronic 的 300 K 完成。pyro-phototronic 效果的基础被在紫外照明之上分析 chargetransfer 过程和 PD 的当前的反应的时间常数彻底地学习。这个工作在 ZnO/perovskite heterostructure 上关于 pyrophototronic 效果介绍深入的理解并且为 ultrafast 相片察觉到, optothermal 察觉,和 biocompatible optoelectronic 探针为相应光电子的设计和发展提供指导。 | Wenbo Peng Ruomeng Yu Xingfu Wang Zhaona Wang Haiyang Zou Yongning He Zhong Lin Wang | 2016 | Nano Research2016，9，12： | 5 |
| 3 | Study on pulsed laser ablation and deposition of ZnO thin films by L-MBE显示文摘ZnO,as a wide-band gap semiconductor,has recently become a new research fo-cus in the field of ultraviolet optoelectronic semiconductors. Laser molecular beam epitaxy(L-MBE) is quite useful for the unit cell layer-by-layer epitaxial growth of zinc oxide thin films from the sintered ceramic target. The ZnO ceramic target with high purity was ablated by KrF laser pulses in an ultra high vacuum to deposit ZnO thin film during the process of L-MBE. It is found that the deposition rate of ZnO thin film by L-MBE is much lower than that by conventional pulsed laser deposition(PLD) . Based on the experimental phenomena in the ZnO thin film growth process and the thermal-controlling mechanism of the nanosecond(ns) pulsed laser abla-tion of ZnO ceramic target,the suggested effective ablating time during the pulse duration can explain the very low deposition rate of the ZnO film by L-MBE. The unique dynamic mechanism for growing ZnO thin film is analyzed. Both the high energy of the deposition species and the low growth rate of the film are really beneficial for the L-MBE growth of the ZnO thin film with high crystallinity at low temperature. | HE YongNing ZHANG JingWen YANG XiaoDong XU QingAn ZHU ChangChun HOU Xun | 2007 | Science China(Technological Sciences)2007，50，3： | 3 |
| 4 | Geographic modeling and simulation systems for geographic research in the new era: Some thoughts on their development and construction显示文摘Regionality,comprehensiveness,and complexity are regarded as the basic characteristics of geography.The exploration of their core connotations is an essential way to achieve breakthroughs in geography in the new era.This paper focuses on the important method in geographic research:Geographic modeling and simulation.First,we clarify the research requirements of the said three characteristics of geography and its potential to address geo-problems in the new era.Then,the supporting capabilities of the existing geographic modeling and simulation systems for geographic research are summarized from three perspectives:Model resources,modeling processes,and operational architecture.Finally,we discern avenues for future research of geographic modeling and simulation systems for the study of regional,comprehensive and complex characteristics of geography.Based on these analyses,we propose implementation architecture of geographic modeling and simulation systems and discuss the module composition and functional realization,which could provide theoretical and technical support for geographic modeling and simulation systems to better serve the development of geography in the new era. | Min CHEN Guonian LV Chenghu ZHOU Hui LIN Zaiyang MA Songshan YUE Yongning WEN Fengyuan ZHANG Jin WANG Zhiyi ZHU Kai XU Yuanqing HE | 2021 | Science China Earth Sciences2021，64，8： | 3 |
| 5 | Prototyping an open environment for sharing geographical analysis models on cloud computing platform显示文摘The sharing of geographical analysis models is of crucial importance for simulating geographic processes and phenomena in the current geographical information systems(e.g.Digital Earth),but there remain some issues that have not been completely resolved.The challenges include,eliminating model heterogeneity and searching for suitable infrastructures to support the open sharing and effective execution of models.Taking advantage of cloud computing,this article aims to address the above issues and develop an open environment for geographical analysis model sharing.On the basis of the analysis of the applicability of cloud computing,the architecture of the open environment is proposed.More importantly,key strategies designed for heterogeneous model description,model encapsulating as well as model deploying and transparent accessing in the cloud are discussed in detail to establish such an environment.Finally,the prototype environment is implemented,and experiments were conducted to verify the environment’s feasibility to support the sharing of geographical analysis models. | Yongning Wen Min Chen Guonian Lu Hui Lin Li He Songshan Yue | 2013 | International Journal of Digital Earth2013，6，4： | 1 |
| 6 | Construction of a virtual lunar environment platform显示文摘Many of the world’s powerful and wealthy nations,including China,have devoted both large amounts of funding and considerable promotion to lunar research and exploration.The launch of Chinese Chang’e-1 satellite and the construction of the scientific observation data platform created a favourable opportunity for research into the lunar geometrical,physical and chemical environment.Based on this background,a Wide Area Network(WAN)based virtual lunar environment was constructed for observation data sharing and further exploration.The systematic architecture and framework were introduced and then strategies of mass data(e.g.lunar digital elevation model,lunar digital orthophoto map and typical thematic lunar data)organisation,integration,management and scheduling were then set up to achieve the 3D visualisation of typical lunar geomorphic features.Furthermore,the integration method of 3D lunar data and the process model of impact craters were studied;thus,the whole lunar and celestial collision process could be dynamically simulated.The results indicate that the WAN-based virtual lunar platform can be used effectively for public information sharing,scientific exploration and further to promote the development of deep space exploration in China. | Min Chen Hui Lin Yongning Wen Li He Mingyuan Hu | 2013 | International Journal of Digital Earth2013，6，5： | 1 |
| 7 | A 4 year retrospec- tive survey of strabismus surgery in Tongren Eye Centre Beijing 显示文摘 | Jie Ying Zhaoyang Xu Yongning He | 2010 | Ophthalmic and Physiological Optics2010，30，3： | 1 |
| 8 | The growth mechanism of SiC film from polyimide LB film显示文摘 | Bangkun Jin Pingsheng He Yongning Sheng etc | 2003 | Journal of Physics and Chemistry of Solids2003，，64： | 1 |
| 9 | Metabolomic analysis of the response of growing pigs to dietary l-arginine supplementation显示文摘 | Qinghua He Xiangfeng Kong Guoyao Wu Pingping Ren Huiru Tang Fuhua Hao Ruilin Huang Tiejun Li Bie Tan Peng Li Zhiru Tang Yulong Yin Yongning Wu | 2009 | Amino Acids2009，，1： | 1 |
| 10 | Metabolomic analysis of the response of growing pigs to dietary l-arginine supplementation显示文摘 | Qinghua He Xiangfeng Kong Guoyao Wu Pingping Ren Huiru Tang Fuhua Hao Ruilin Huang Tiejun Li Bie Tan Peng Li Zhiru Tang Yulong Yin Yongning Wu | 2009 | Amino Acids2009，，1： | 1 |
| 11 | Cbln1和Cbln4在结构上相似但与GluD2相互作用显著不同显示文摘文章简介本研究以参与突触形成的Cbln家族为研究对象。Cbln家族包含4个成员,其中Cbln1通过在突触间隙中结合Nrxn蛋白和δ-谷氨酸受体参与突触形成;然而,尽管Cbln4与Cbln1有高达74%的序列等同性,文献报道Cbln4不能结合Nrxn蛋白和δ-谷氨酸受体,而是DCC的配体。 | 钟琛 Jinlong Shen Huibing Zhang Guangyi Li Senlin Shen Fang Wang Kuan Hu Longxing Cao Yongning He 丁建平 | 2018 | 科学新闻2018，0，4： | 0 |
| 12 | Heteroatom anchors Fe-Mn dual-atom catalysts with bi-functional oxygen catalytic activity for low-temperature rechargeable flexible Zn-air batteries显示文摘M-N-C(M=Fe,Co,Ni,etc.) catalyst owns high catalytic activity in the oxygen catalytic reaction which is the most likely to replace the Pt-based catalysts.But it is still a challenge to further increase the active site density.This article constructs the high-efficiency FeMn-N/S-C-1000 catalyst to realize ORR/OER bifunctional catalysis by hetero-atom,bimetal(Fe,Mn) doped simultaneously strategy.When evaluated it as bi-functional electro-catalysts,FeMn-N/S-C-1000 exhibits excellent catalytic activity(E_(1/2)=0.924 V,E_(j=10)=1.617 V) in alkaline media,outperforms conventional Pt/C,RuO_(2) and most non-precious-metal catalysts reported recently,Such outstanding performance is owing to N,S co-coordinated with metal to form multi-types of single atom,dual atom active sites to carry out bi-catalysis.Importantly,nitrite poison test provides the proof that the active sites of FeMn-N/S-C are more than that of single-atom catalysts to promote catalytic reactions directly.To better understand the local structure of Fe and Mn active sites,XAS and DFT were employed to reveal that FeMn-N_5/S-C site plays the key role during catalysis.Notably,the FeMn-N/S-C-1000 based low-temperature rechargeable flexible Zn-air also exhibits superior discharge performance and extraordinary durability at-40℃.This work will provide a new idea to design diatomic catalysts applied in low-temperature rechargeable batteries. | Yuting He Hongtao Li Yi Wang Yufei Jia Yongning Liu Qiang Tan | 2024 | Journal of Energy Chemistry2024，90，3： | 0 |
| 13 | 发热通过Hsp90-α4整合素热感应信号通路促进T淋巴细胞迁移显示文摘文章简介发热是机体受到病原体感染、产生损伤或者炎症后的一种复杂的生理应激反应。发热可以促进淋巴细胞迁移到次级淋巴器官或者炎症部位而促进免疫反应,对免疫稳态维持和免疫监视非常重要,但是目前对发热调控淋巴细胞黏附和迁移的机制还不清楚。本研究中,课题组发现:发热可以通过热休克蛋白90(heat shock protein 90,Hsp90)诱导α4整合素活化并传递下游信号通路。 | 林昶东 张有华 Kun Zhang YaJuan Zheng Ling Lu HaiShuang Chang Hui Yang YanRong Yang YaoYing Wan ShiHui Wang MengYa Yuan ZhanJun Yan RongGuang Zhang YongNing He GaoXiang Ge Dianqing Wu 陈剑峰 | 2020 | 科学新闻2020，，2： | 0 |
| 14 | Hierarchical Control of DC Microgrids Robustness and Smartness显示文摘This paper investigates the hierarchical control of DC microgrids.Compared to AC microgrids,DC microgrids encounter complicated converter-level control,and simplified system-level management.To address these characteristics,a new three-level control hierarchy is introduced.The converter control level encapsulates sophisticated converter topologies and inner control loops into a black-box representation.The voltage coordination level uses DC voltage signals to coordinate both static and transient power sharing.The energy management level optimizes the power flow and power quality in a broader scope through communication.This architecture lowers the focus of control to bottom levels.More functions are allocated to the converter control and voltage coordination levels.They can maintain basic microgrid performance with fully local control,thereby ensuring reliable power supply in case of communication failures.Moreover,taking advantage of DC microgrids’simplified system-level operation patterns,the energy management level uses straightforward algorithms to achieve intelligent functions.As a result,this architecture achieves both robust and smart control by exploring DC microgrids’critical features. | Yunjie Gu Heya Yang Wei Sun Yongning Chi Wuhua Li Xiangning He | 2020 | CSEE Journal of Power and Energy Systems2020，6，2： | 0 |
| 15 | Statement on Establishment of A Provisional Health Based Guidance Value for Dietary Exposure to Cadmium in China显示文摘The National Health Commission of the People’s Republic of China and the State Administration for Market Regulation have issued the National Food Safety Standard(GB2762-2022),which delineates the maximum limits(ML)of contaminants in food.This standard will be implemented on June 30,2023.It currently maintains the ML of cadmium in rice(including unhusked rice,husked rice,polished rice)at 0.2 mg/kg,a value first established 40 years ago in GBn238-1984. | Jinfang Sun Yi Shao Gengsheng He Yongning Wu | 2023 | China CDC weekly2023，5，22： | 0 |
| 16 | Dual-mode Switching Fault Ride-through Control Strategy for Self-synchronous Wind Turbines显示文摘The installed capacity of renewable energy generation has continued to grow rapidly in recent years along with the global energy transition towards a 100%renewable-based power system.At the same time,the grid-connected large-scale renewable energy brings significant challenges to the safe and stable operation of the power system due to the loss of synchronous machines.Therefore,self-synchronous wind turbines have attracted wide attention from both academia and industry.However,the understanding of the physical operation mechanisms of self-synchronous wind turbines is not clear.In particular,the transient characteristics and dynamic processes of wind turbines are fuzzy in the presence of grid disturbances.Furthermore,it is difficult to design an adaptive fault ride-through(FRT)control strategy.Thus,a dual-mode switching FRT control strategy for self-synchronous wind turbines is developed.Two FRT control strategies are used.In one strategy,the amplitude and phase of the internal potential are directly calculated according to the voltage drop when a minor grid fault occurs.The other dual-mode switching control strategy in the presence of a deep grid fault includes three parts:vector control during the grid fault,fault recovery vector control,and self-synchronous control.The proposed control strategy can significantly mitigate transient overvoltage,overcurrent,and multifrequency oscillation,thereby resulting in enhanced transient stability.Finally,simulation results are provided to validate the proposed control strategy. | Xinshou Tian Yongning Chi Peng Cheng Wei He Yunpeng Zhou Jianzhu Hu | 2023 | Journal of Modern Power Systems and Clean Energy2023，11，2： | 0 |
| 17 | An Improved Prediction Model of Vortex Shedding Noise from Blades of Fans显示文摘The main source of the noise of an axial flow fan is the fluctuating pressure field on blade surfaces caused by the shedding of vortices at the trailing edge of blades.An analytical model to predict the vortex shedding noise generated at the trailing edge of blades of axial flow fans was proposed by Lee in 1993.In this model,for mathematical convenience,an idealized vortex street is considered.However,the agreement between the analytical results and the experimental data needs to be improved because of the simplification about the Karman vortex street in the wake of blade.In the present study,a modified model is proposed based on the prediction model by Lee.The boundary layer theory is used to analyze and calculate the boundary layer development on both the pressure and the suction sides of blades.Considering the effect of boundary layer separation on the location of noise source,the predicted overall sound pressure level compares favorably with the experimental data of an axial fan.In the calculation of A-weighted sound pressure level(La),considering the effect of static pressure on radiate energy,the predicted broadband noise with the modified model compares favorably with the experimental data of a multiblade centrifugal fan. | DOU Huashu LI Zhehong LIN Peifeng WEI Yikun CHEN Yongning CAO Wenbin HE Haijiang | 2016 | Journal of Thermal Science2016，25，6： | 0 |
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