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| 1 | Effects of Short-Term Forest Bathing on Human Health in a Broad-Leaved Evergreen Forest in Zhejiang Province,China显示文摘Objective To investigate the effects of short-term forest bathing on human health.Methods Twenty healthy male university students participated as subjects and were randomly divided into two groups of 10.One group was sent on a two-night trip to a broad-leaved evergreen forest,and the other was sent to a city area.Serum cytokine levels reflecting inflammatory and stress response,indicators reflecting oxidative stress,the distribution of leukocyte subsets,and plasma endothelin-1 (ET-1) concentrations were measured before and after the experiment to evaluate the positive health effects of forest environments.A profile of mood states (POMS) evaluation was used to assess changes in mood states.Results No significant differences in the baseline values of the indicators were observed between the two groups before the experiment.Subjects exposed to the forest environment showed reduced oxidative stress and pro-inflammatory level,as evidenced by decreased malondialdehyde,interleukin-6,and tumor necrosis factor α levels compared with the urban group.Serum cortisol levels were also lower than in the urban group.Notably,the concentration of plasma ET-1 was much lower in subjects exposed to the forest environment.The POMS evaluation showed that after exposure to the forest environment,subjects had lower scores in the negative subscales,and the score for vigor was increased.Conclusion Forest bathing is beneficial to human health,perhaps through preventive effects related to several pathological factors. | MAO Gen Xiang LAN Xiao Guang CAO Yong Bao CHEN Zhuo Mei HE Zhi Huat LV Yuan Dong WANG Ya Zhen HU Xi Lian WANG Guo Fu YAN Jing | 2012 | Biomedical and Environmental Sciences2012，25，3： | 20 |
| 2 | Additive Benefits of Twice Forest Bathing Trips in Elderly Patients with Chronic Heart Failure显示文摘长期的心失败(CHF ) ,源于各种各样的心血管的疾病(CVD ) 的后果的临床的症候群,逐渐地正在成为病态和死亡的一个全球原因。我们更早证明了洗旅行的一个 4 天的森林能在病人上向附属治疗学的影响提供 CHF。为了进一步调查影响和森林洗澡的最佳的频率的持续时间,与 CHF 在病人摔倒,我们招募了经历了在 4 个星期以后再洗旅行的第一个森林并且也就是,随机把他们分成了二个组的那些对象城市的控制组(城市)和洗组(森林)的森林。在洗旅行的第二个 4 天的森林以后,我们象氧化应力一样在大脑 natriuretic 肽层次,心失败的 biomarker,和稀释煽动性的回答观察了稳定的衰落。因此,这探索研究表明了添加剂好处两次,森林洗澡与 CHF 在老病人摔倒,它能进一步为在 CVD 分析如此的干预的效果铺平道路。 | MAO Gen Xiang CAO Yong Bao YANG Yan CHEN Zhuo Mei DONG Jian Hua CHEN Sha Sha WU Qing LYU Xiao Ling JIA Bing Bing YAN Jing WANG Guo Fu | 2018 | Biomedical and Environmental Sciences2018，31，2： | 18 |
| 3 | High-resolution, full-color quantum dot light-emitting diode display fabricated via photolithography approach显示文摘Displays play an extremely important role in modern information society,which creates a never-ending demand for the new and better products and technologies.The latest requirements for novel display technologies focus on high resolution and high color gamut.Among emerging technologies that include organic light-emitting diode(OL ED),micro light-emiting diode(micro-LED),quantum dot light-emitting diode(QLED),laser display,holographic display and others,QLED is promising owing to its intrinsic high color gamut and the possibility to achieve high resolution with photolithography approach.However,previously demonstrated photolthography techniques suffer from reduced device performance and color Impurities in subpixels from the process.In this study,we demonstrated a sacrificial layer assisted patterming(SLAP)approach,which can be applied in conjunction with photolithography to fabricate high-resolution,full-colo quantum dot(QD)patterns.In this approach,the negative photoresist(PR)and sacrificial layer(SL)were uilized to determine the pixels for QD deposition,while at the same time the SL helps protect the QD layer and keep it intact(named PR-SL approach).To prove this method's viability for QLED display manufacture,a 500-ppi,full-color passive matrix(PM)-QLED prototype was fabricated via this process.Results show that there were no color impurities in the subpixels,and the PM-QL ED has a high color gamut of 114%National Television Standards Committee(NTSC).To the best of our knowledge,this is the first ull-olor QLED prototype with such a high resolution.We anticipate that this innovative patteming technique will open a new horizon for future display technologies and may lead to a disruptive and innovative change in display industry. | Wenhai Mei Zhenqi Zhang Aidi Zhang Dong Li Xiaoyuan Zhang Haowei Wang Zhuo Chen Yanzhao Li Xinguo Li Xiaoguang Xu | 2020 | Nano Research2020，13，9： | 6 |
| 4 | Medical Assessment on Forest Therapy Base in Zhejiang Province, China显示文摘According to the‘13^th Five-Year plan for forestry development’of State Forestry and Grassland Administration,500 forest therapy(also known as forest bathing or Shinrin-yoku in Japan)bases and 5–10 international cooperation demonstration bases will be set up in China,by 2020.So,it’s important to provide evidence about the benefits of specific forest environmental to human health,namely medical assessment on forest therapy base. | WU Qing YE Bing CHEN Zhuo Mei LYU Xiao Ling REN Xiao Xu DONG Jian Hua WANG Guo Fu | 2019 | Biomedical and Environmental Sciences2019，32，12： | 4 |
| 5 | Inhibiting Hv1 channel in peripheral sensory neurons attenuates chronic inflammatory pain and opioid side effects显示文摘Both opioids and nonsteroidal anti-inflammatory drugs(NSAIDS)produce deleterious side effects and fail to provide sustained relief in patients with chronic inflammatory pain.Peripheral neuroinflammation(PN)is critical for initiation and development of inflammatory pain.A better understanding of molecular mechanisms underlying PN would facilitate the discovery of new analgesic targets and the development of new therapeutics.Emerging evidence suggests that peripheral sensory neurons are not only responders to painful stimuli,but are also actively engaged in inflammation and immunity,whereas the intrinsic regulatory mechanism is poorly understood.Here we report the expression of proton-selective ion channel Hv1 in peripheral sensory neurons in rodents and humans,which was previously shown as selectively expressed in microglia in mammalian central nervous system.Neuronal Hv1 was up-regulated by PN or depolarizing stimulation,which in turn aggravates inflammation and nociception.Inhibiting neuronal Hv1 genetically or by a newly discovered selective inhibitor YHV98-4 reduced intracellular alkalization and ROS production in inflammatory pain,mitigated the imbalance in downstream SHP-1-pAKT signaling,and also diminished pro-inflammatory chemokine release to alleviate nociception and morphine-induced hyperalgesia and tolerance.Thus,our data reveal neuronal Hv1 as a novel target in analgesia strategy and managing opioids-related side effects. | Qiansen Zhang Yimin Ren Yiqing Mo Peipei Guo Ping Liao Yuncheng Luo Jie Mu Zhuo Chen Yang Zhang Ya Li Linghui Yang Daqing Liao Jie Fu Juwen Shen Wei Huang Xuewen Xu Yanyan Guo Lianghe Mei Yunxia Zuo Jin Liu Huaiyu Yang Ruotian Jiang | 2022 | Cell Research2022，32，5： | 3 |
| 6 | Simulation of moving boundary of the reaction shaft in a flash smelting furnace显示文摘As to solve the online monitoring of the inner temperatur e and freezing profile of the reaction shaft of flash smelting furnace, simulation of the wall in the reaction shaft in a flash smelting furnace was made through numerical computation. The computational results are very near the data got in s ite. The error of the moving boundary is approximately 3%, and that of the tempe rature is less than 5%. It is proved that the simulation software is applicable for practice to monitor the temperature and moving boundary inside the hearth on line. Based on a large number of the data computed, the relation between the cha nge of the moving boundary and inner temperature is summarized, and the great in fluence of the cooling system on the forming and stability of the moving boundar y inside the hearth is emphasized, which provide the theoretical bases for optim izing the flash smelting operation. | CHEN Zhuo 1,MEI Chi 1,CHEN Hong-rong 1,MO Jiao 2 (1 Institute on Simulation and Optimization of Pyro-installation, Central Sout h University, Changsha 410083, China 2 Science School, Beijing University of Posts and Telecommunications, Beijing 1 | 2001 | Journal of Central South University2001，13，3： | 3 |
| 7 | Biomarkers of aging显示文摘Aging biomarkers are a combination of biological parameters to(i)assess age-related changes,(ii)track the physiological aging process,and(iii)predict the transition into a pathological status.Although a broad spectrum of aging biomarkers has been developed,their potential uses and limitations remain poorly characterized.An immediate goal of biomarkers is to help us answer the following three fundamental questions in aging research:How old are we?Why do we get old?And how can we age slower?This review aims to address this need.Here,we summarize our current knowledge of biomarkers developed for cellular,organ,and organismal levels of aging,comprising six pillars:physiological characteristics,medical imaging,histological features,cellular alterations,molecular changes,and secretory factors.To fulfill all these requisites,we propose that aging biomarkers should qualify for being specific,systemic,and clinically relevant. | Aging Biomarker Consortium Hainan Bao Jiani Cao Mengting Chen Min Chen Wei Chen Xiao Chen Yanhao Chen Yu Chen Yutian Chen Zhiyang Chen Jagadish K Chhetri Yingjie Ding Junlin Feng Jun Guo Mengmeng Guo Chuting He Yujuan Jia Haiping Jiang Ying Jing Dingfeng Li Jiaming Li Jingyi Li Qinhao Liang Rui Liang Feng Liu Xiaoqian Liu Zuojun Liu Oscar Junhong Luo Jianwei Lv Jingyi Ma Kehang Mao Jiawei Nie Xinhua Qiao Xinpei Sun Xiaoqiang Tang Jianfang Wang Qiaoran Wang Siyuan Wang Xuan Wang Yaning Wang Yuhan Wang Rimo Wu Kai Xia Fu-Hui Xiao Lingyan Xu Yingying Xu Haoteng Yan Liang Yang Ruici Yang Yuanxin Yang Yilin Ying Le Zhang Weiwei Zhang Wenwan Zhang Xing Zhang Zhuo Zhang Min Zhou Rui Zhou Qingchen Zhu Zhengmao Zhu Feng Cao Zhongwei Cao Piu Chan Chang Chen Guobing Chen Hou-Zao Chen Jun Chen Weimin Ci Bi-Sen Ding Qiurong Ding Feng Gao Jing-Dong JHan Kai Huang Zhenyu Ju Qing-Peng Kong Ji Li Jian Li Xin Li Baohua Liu Feng Liu Lin Liu Qiang Liu Qiang Liu Xingguo Liu Yong Liu Xianghang Luo Shuai Ma Xinran Ma Zhiyong Mao Jing Nie Yaojin Peng Jing Qu Jie Ren Ruibao Ren Moshi Song Zhou Songyang Yi Eve Sun Yu Sun Mei Tian Shusen Wang Si Wang Xia Wang Xiaoning Wang Yan-Jiang Wang Yunfang Wang Catherine CL Wong Andy Peng Xiang Yichuan Xiao Zhengwei Xie Daichao Xu Jing Ye Rui Yue Cuntai Zhang Hongbo Zhang Liang Zhang Weiqi Zhang Yong Zhang Yun-Wu Zhang Zhuohua Zhang Tongbiao Zhao Yuzheng Zhao Dahai Zhu Weiguo Zou Gang Pei Guang-Hui Liu | 2023 | Science China(Life Sciences)2023，66，5： | 2 |
| 8 | Computer simulation model for spherical particle filled composite materials 显示文摘 | Chen Zhuo Huang Zhixiong Zhang Ming Shl Minxian Qin Yah Mei Qilin | 2011 | Key Eng Mater2011，47，： | 1 |
| 9 | Arsenic promotes angiogenesis in vitro via a heme oxygenase-1-dependent mechanism显示文摘 | Dan Meng Xin Wang Qingshan Chang Andrew Hitron Zhuo Zhang Mei Xu Gang Chen Jia Luo Binghua Jiang Jing Fang Xianglin Shi | 2010 | Toxicology and Applied Pharmacology2010，，3： | 1 |
| 10 | Fabrication of large-area uniform carbon nanotube foams as near-critical-density targets for laser–plasma experiments显示文摘Carbon nanotube foams(CNFs)have been successfully used as near-critical-density targets in the laser-driven acceleration of high-energy ions and electrons.Here we report the recent advances in the fabrication technique of such targets.With the further developed floating catalyst chemical vapor deposition(FCCVD)method,large-area(>25 cm^(2))and highly uniform CNFs are successfully deposited on nanometer-thin metal or plastic foils as double-layer targets.The density and thickness of the CNF can be controlled in the range of 1−13 mg/cm^(3)and 10−200µm,respectively,by varying the synthesis parameters.The dependence of the target properties on the synthesis parameters and the details of the target characterization methods are presented for the first time. | Pengjie Wang Guijun Qi Zhuo Pan Defeng Kong Yinren Shou Jianbo Liu Zhengxuan Cao Zhusong Mei Shirui Xu Zhipeng Liu Shiyou Chen Ying Gao Jiarui Zhao Wenjun Ma | 2021 | High Power Laser Science and Engineering2021，9，2： | 1 |
| 11 | Engineering of electrolyte ion channels in MXene/holey graphene electrodes for superior supercapacitive performances显示文摘MXene has given great promises to superca-pacitor electrode material due to its high conductivity and redox properties.However,the self-agglomeration of the MXene lamella will reduce its contact area with the elec-trolyte and generate a tortuous transportation pathway of the electrolyte ions,thereby reducing its capacitive per-formance and rate capability.In this work,we engineered the electrolyte ion channels by adjusting the MXene lamella size and inserting holey graphene(HG)nanosheets into the interlayer of the MXene flakes.The developed MXene/HG electrode can not only avoid the self-restack-ing of MXene but also provide unimpeded ion transport channels.As a result,the supercapacitive and rate perfor-mances of the small MXene lamella-based MXene/HG(S-MXene/HG)supercapacitor are prominently ameliorated.By adjusting the content of HG,the S-MXene/HG0.05 electrode exhibits excellent gravimetric capacitance of 446 F·g^(-1)and a rate capability of 77.5%.The S-MXene/HG0.05-based symmetric supercapacitor provides an impressive energy density of 14.84 Wh·kg^(-1)with excellent cyclic stability of 96%capacitance retention after 10,000 cycles.This demonstration of the engineering of the ion channels shows great potential in two-dimensional mate-rial-based supercapacitor electrodes. | Zhuo Cai Yi-Fei Ma Mei Wang A-Niu Qian Zhao-Min Tong Lian-Tuan Xiao Suo-Tang Jia Xu-Yuan Chen | 2022 | Rare Metals2022，41，6： | 1 |
| 12 | Research on Classification Effectiveness of the Novel Mamdani Fuzzy Classifier显示文摘 | Zhi Sheng Jing Ze Long Zhou Chen Mei Xiang Yong Su Zhuo Yang Yi Tao | 2014 | Applied Mechanics and Materials . 2014 (511)2014，，511： | 1 |
| 13 | Dorsomorphin induces cancer cell apoptosis and sensitizes cancer cells to HSP90 and proteasome inhibitors by reducing nuclear heat shock factor 1 levels显示文摘Objective: Heat shock factor 1(HSF1), a transcriptional regulator of heat shock proteins(HSPs), is an attractive therapeutic target for cancer. However, only a few HSF1 inhibitors have been identified so far.Methods: The mRNA and protein levels of HSF1, HSPs, cleaved PARP, and phosphorylated HSF1 were examined by real-time PCR and Western blot. Forced expression, RNA interference, and immunofluorescence assay were used for mechanistic studies.Cell viability and apoptosis were measured by WST-8 assay and flow cytometry, respectively. Xenograft studies were performed in nude mice to evaluate the effect of dorsomorphin and an HSP90 inhibitor on tumor growth.Results: Dorsomorphin suppressed multiple stimuli-induced and constitutive HSPs expression in cancer cells. Mechanistic studies revealed that dorsomorphin reduced heat-induced HSP expression independent of adenosine monophosphate activated protein kinase. Dorsomorphin reduced heat-stimulated HSF1 Ser320 phosphorylation and nuclear translocation, as well as resting nuclear HSF1 levels in cancer cells. Dorsomorphin induced cancer cell apoptosis by inhibiting HSF1 expression. A structure-activity study revealed that the 4-pyridyl at the 3-site of the pyrazolo [1, 5-a]pyrimidine ring is critical for the anti-HSF1 activities of dorsomorphin. Dorsomorphin sensitized cancer cells to HSP90 and proteasome inhibitors and inhibited HSP70 expression induced by these inhibitors in vitro. In tumor-bearing nude mice, dorsomorphin enhanced HSP90 inhibitor-induced cancer cell apoptosis, tumor growth inhibition, and HSP70 expression.Conclusions: Dorsomorphin is an HSF1 inhibitor. It induces cancer cell apoptosis, sensitizes cancer cells to both HSP90 and proteasome inhibitors, and suppresses HSP upregulation by these drugs, which may prevent the development of drug resistance.Hence, dorsomorphin and its derivates may serve as potential precursors for developing drugs against cancer. | Na Li Ting Wang Zongmeng Li Xiaoli Ye Bo Deng Shu Zhuo Pengle Yao Mengmei Yang Hong Mei Xiaofang Chen Tengfei Zhu Shiting Chen Hui Wang Jiming Wang Yingying Le | 2019 | Cancer Biology & Medicine2019，16，2： | 1 |
| 14 | Sequence Determination of Cd and Pb in Honey by Incomplete Digestion-High Resolution Continuum Source Graphite Furnace Atomic Absorption Spectrometry显示文摘 | Zhi Sheng Jing Ze Long Zhou Chen Mei Xiang Yong Su Zhuo Yang Yi Tao | 2014 | Applied Mechanics and Materials2014，，511： | 1 |
| 15 | Arthroscopy assisted mini- mally invasive surgical treatment of tibial plateau fractures in 48 pa- tients 显示文摘 | Chen Zhuo Wu Junbiao dong -mei yu | 2014 | Chinese journal of bone and joint injury2014，12，： | 1 |
| 16 | Correction to:Development of short prototype of dual aperture quadrupole magnet for CEPC ring显示文摘While typesetting the article,in the Figs.13 and 17 there were several errors introduced.The correct Figs.13 and 17 are copied below:The original article has been corrected. | Mei Yang Fu-San Chen Ya-Feng Wu Zhuo Zhang Bao-Gui Yin Bin Na Zhan-Jun Zhang | 2023 | Nuclear Science and Techniques2023，34，7： | 0 |
| 17 | Research Progress of Nuclear Astrophysics Physics:Progress of Jinping Underground Laboratory for Nuclear Astrophysics Experiment JUNA显示文摘1 Progress of this program This program is supported by the China Jinping Underground Laboratory(CJPL)and the direct measurement of stellar key reactions of(α,γ),(α,n),(p,γ)and(p,α)will be precisely carried out at the merit of current project by utilizing high stability and intensity accelerator,high efficiency detector and the shielding of extremely low background. | LIU Wei-ping LI Zhi-hong HE Jian-jun TANG Xiao-dong LIAN Gang GUO Bing AN Zhu CHEN Qing-hao CHEN Xiong-jun CHEN Yang-ping CHEN Zhi-jun CUI Bao-qun DU Xian-chao FU Chang-bo GAN Lin HAN Zhi-yu HE Guo-zhu A.Heger HOU Su-qing HUANG Han-xiong HUANG Ning JIA Bao-lu JIANG Li-yang S.Kubono LI Jian-min LI Kuo-ang LI Tao LI Xin-yue LI Yun-ju M.Lugaro LUO Xiao-bing MA Shao-bo MEI Dong-ming QIAN Yong-zhong QIN Jiu-chang REN Jie SU Jun SUN Liang-ting TAN Wan-peng I.Tanihata WANG Peng WANG You-bao WU Qi XU Shi-wei YAN Sheng-quan YANG Li-tao YU Xiang-qing YUE Qian ZENG Sheng ZHANG Huan-yu ZHANG Hui ZHANG Li-yong ZHANG Ning-tao ZHANG Qi-wei ZHANG Tao ZHANG Xiao-peng ZHANG Xue-zhen ZHANG Zi-min ZHAO Wei ZHAO Zhuo ZHOU Chao ZHOU Yong | 2015 | Annual Report of China Institute of Atomic Energy2015，，1： | 0 |
| 18 | Synchronous post-acceleration of laser-driven protons in helical coil targets by controlling the current dispersion显示文摘Post-acceleration of protons in helical coil targets driven by intense,ultrashort laser pulses can enhance ion energy by utilizing the transient current from the targets’self-discharge.The acceleration length of protons can exceed a few millimeters,and the acceleration gradient is of the order of GeV/m.How to ensure the synchronization between the accelerating electric field and the protons is a crucial problem for efficient post-acceleration.In this paper,we study how the electric field mismatch induced by current dispersion affects the synchronous acceleration of protons.We propose a scheme using a two-stage helical coil to control the current dispersion.With optimized parameters,the energy gain of protons is increased by four times.Proton energy is expected to reach 45 MeV using a hundreds-of-terawatts laser,or more than 100 MeV using a petawatt laser,by controlling the current dispersion. | Zhipeng Liu Zhusong Mei Defeng Kong Zhuo Pan Shirui Xu Ying Gao Yinren Shou Pengjie Wang Zhengxuan Cao Yulan Liang Ziyang Peng Jiarui Zhao Shiyou Chen Tan Song Xun Chen Tianqi Xu Xueqing Yan Wenjun Ma | 2023 | High Power Laser Science and Engineering2023，11，4： | 0 |
| 19 | Superconducting multipole wiggler with large magnetic gap for HEPS-TF显示文摘A 16-pole superconducting multipole wiggler with a large gap of 68 mm was designed and fabricated to serve as a multipole wiggler for HEPS-TF.The wiggler consists of 16 pairs of NbTi superconducting coils with a period length of 170 mm,and its maximum peak field is 2.6 Tesla.In magnet design,magnet poles were optimized.Furthermore,the Lorentz force on the coils and electromagnetic force between the upper and lower halves were computed and analyzed along with the stored energy and inductance at different currents.To enhance the critical current of the magnet coil,all the pole coils selected for the magnet exhibited excellent performance,and appropriate prestress derived from the coil force analysis was applied to the pole coils during magnet assembly.The entire magnet structure was immersed in 4.2-K liquid helium in the cryostat cooled solely by four two-stage cryocoolers,and the performance test of the superconducting wiggler was appropriately completed.Based on the measured results,the first and second field integrals on the axis of the superconducting wiggler were significantly improved at different field levels after the compensation of the corrector coils.Subsequently,the wiggler was successfully installed in the storage ring of BEPCII operation with beams. | Xian-Jing Sun Fu-San Chen Xiang-Chen Yang Wan Chen Xiao-Juan Bian Min-Xian Li Rui Ge Miao-Fu Xu Yao Gao Jin-Can Wang Hui-Hua Lu Jian-She Cao Zhi-Qiang Li Zhuo Zhang Rui Ye Xiang-Zhen Zhang Shuai Li Bao-Gui Yin Mei Yang Ling-Ling Gong Da-Heng Ji Lin Bian Ran Liang Ya-Jun Sun Hong Shi | 2022 | Nuclear Science and Techniques2022，33，2： | 0 |
| 20 | STUDY ON GLYCOCONJUGATE CHANGES ON CELL SURFACE IN PROGRESSIVE DEVELOPMENT OF PULMONARY TUMOR显示文摘Aim: To investigate glycoconjugate changes on the cell surface of proliferative lesions and neoplasms of mice lungs at various stages of tumorigenesis, the relation between progressive development of mouse pulmonary tumors and expression of cell surface saccharide. Materials and methods: Thirty - one male A/J strain mice at 5 weeks of age were treated intraperitoneally with a single injection of 20 - methylcholanthrene (20 - MC), 292 pulmonary lesions including 31 hyperplasias, 145 alveolar adenomas, 61 papillary adenomas, 55 papillary adenocarcinomas and their combined type were obtained. The binding affinities of cells in normal respiratory epithelia and in proliferative lesions to four peroxidases - conjugated lectins, Maclura pomifera agglutinin (MPA), Arachis hypogea agglutinin (PNA), Ricinus communis agglutinin (RCA), and wheat germ agglutinin (WGA) were examined. Results: Cells of hyperplasia and alveolar adenoma showed fairly strong affinity to all the four lectins. However, part of papillary adenoma cells and greater part of papillary adenocarcinoma cells lost their binding affinity to MPA, PNA, and RCA, but not to WGA. The bindings of MPA, PNA and RNA were detected predominently on the luminal surfaces of benign tumors but not on the luminal surfaces of malignant tumors. WGA might bind to varied types of benign and malignant tumors. Pretreated with neuraminidase, the lesions enhanced the staining intensity for the four lectins, the binding sites of WGA to malignant tumor cells were numerous. A distinct difference in lectin binding affinity between hyperplasia / alveolar adenoma/papillary adenoma and papillary adenocarcinoma was clearly shown( x2 = 46.89, P < 0.01, x2 = 36.77, P < 0.01 and x2 = 52.87, P < 0.01 ) in this experiment. The complex glycoconjugates on the cell surface of malignant and benign lesions during the development of pulmonary tumor were changed,malignant tumor cells differed from the surface of benign tumor cells, the levels of total sialic acid were higher in malignant tumor cells than in benign lesions. Conclusions: The expressions of glycoconjugates on cell surface by lectins may assist differential diagnosis of the malignant and benign lung lesions. | WANG Xiao - mei, SHAN Jun, CHEN Zhuo - huai( Department of Pathology, Shenzhen People’s Hospital of Guangdong Province, Shenzhen 518020, China Department of Radiology, Shenzhen People s Hospital, Shenzhen 518020, China) | 2002 | 中国体视学与图像分析2002，7，2： | 0 |
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