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| 1 | Arabidopsis F-box gene FOA1 involved in ABA signaling显示文摘The expression of FOA1(F-box overexpressed/oppressed ABA signaling) in different organs of Arabidopsis,and in response to ABA and NaCl,was analyzed.The expression level of FOA1 is higher in the root and is lower in the stem,and is induced rapidly by ABA and NaCl.The phenotypes of T-DNA insertion mutant foa1 and FOA1 overexpression lines FOA1ox1 and FOA1ox2 were analyzed.The foa1 mutant exhibited a lower germination rate,shorter root length,more stomatal opening,increased proline accumulation and hypersensitivity to ABA compared with the wild type.In contrast,the overexpression lines showed lower sensitivity to ABA than the wild type.The expression levels of several ABA and stress-responsive transcription factors and genes were altered in the foa1 mutant in response to ABA.Compared with the wild type,the expression levels of ABA-responsive transcription factors were higher,but ABA and stress-responsive genes were lower in foa1 mutant.This study demonstrates that FOA1 is an ABA signaling-related gene,and may play a negative role in ABA signaling. | PENG Juan YU DaShi WANG LiQun XIE MinMin YUAN CongYing WANG Yu TANG DongYing ZHAO XiaoYing LIU XuanMing | 2012 | Science China(Life Sciences)2012，55，6： | 12 |
| 2 | Cell-free plasma hypermethylated CASZ1, CDH13 and ING2 are promising biomarkers of esophageal cancer显示文摘Identifying sensitive and specific biomarkers for early detection of cancer is immensely imperative for early diagnosis and treatment and better clinical outcome of cancer patients. This study aimed to construct a specific DNA methylation pattern of cancer suppressor genes and explore the feasibility of applying cell-free DNA based methylation as a biomarker for early diagnosis of esophageal squamous cell carcinoma(ESCC). We recruited early stage ESCC patients from Yangzhong County, China. The Illumina Infinium 450 K Methylation BeadChip was used to construct a genome-wide DNA methylation profile. Then, differentiated genes were selected for the validation study using the Sequenom MassARRAY platform. The frequency of methylation was compared between cancer tissues, matched cell-free DNAs and normal controls. The specific methylation profiles were constructed, and the sensitivity and specificity were calculated. Seven CG sites in three genes CASZ1, CDH13 and ING2 were significantly hypermethylated in ESCC as compared with normal controls. A significant correlation was found between the methylation of DNA extracted from cancer tissues and matched plasma cell-free DNA, either for individual CG site or for cumulative methylation analysis. The sensitivity and specificity reached 100% at an appropriate cut-point using these specific methylation biomarkers. This study revealed that aberrant DNA methylation is a promising biomarker for molecular diagnosis of esophageal cancer. Hypermethylation of CASZ1,CDH13 and ING2 detected in plasma cell-free DNA can be applied as a potential noninvasive biomarker for diagnosis of esophageal cancer. | Huanqiang Wang Congying Yang Siyuan Wang Tian Wang Jingling Han Kai Wei Fucun Liu Jida Xu Xianzhen Peng Jianming Wang | 2018 | The Journal of Biomedical Research2018，32，6： | 6 |
| 3 | Uniformly grown PtCo-modified C03O4 nanosheets as a highly efficient catalyst for sodium borohydride electrooxidation显示文摘 | Congying Song Dongming Zhang Bin Wang Zhuang Cai Peng Yan Yang Sun Ke Ye Dianxue Cao Kui Cheng Guiling Wang | 2016 | Nano Research2016，9，11： | 5 |
| 4 | Magnetic Fe_3O_4-Reduced Graphene Oxide Nanocomposites-Based Electrochemical Biosensing显示文摘An electrochemical biosensing platform was developed based on glucose oxidase(GOx)/Fe3O4-reduced graphene oxide(Fe3O4-RGO) nanosheets loaded on the magnetic glassy carbon electrode(MGCE).With the advantages of the magnetism, conductivity and biocompatibility of the Fe3O4-RGO nanosheets, the nanocomposites could be facilely adhered to the electrode surface by magnetically controllable assembling and beneficial to achieve the direct redox reactions and electrocatalytic behaviors of GOx immobilized into the nanocomposites. The biosensor exhibited good electrocatalytic activity, high sensitivity and stability. The current response is linear over glucose concentration ranging from 0.05 to 1.5 m M with a low detection limit of0.15 μM. Meanwhile, validation of the applicability of the biosensor was carried out by determining glucose in serum samples. The proposed protocol is simple, inexpensive and convenient, which shows great potential in biosensing application. | Lili Yu Hui Wu Beina Wu Ziyi Wang Hongmei Cao Congying Fu Nengqin Jia | 2014 | Nano-Micro Letters2014，6，3： | 4 |
| 5 | Ag@Au core/shell triangular nanoplates with dual enzyme-like properties for the colorimetric sensing of glucose显示文摘Due to the serious harm of diabetes to human health,development of sensitive assays for glucose level is of high significance for early prevention and treatment of diabetes.Currently,most conventional enzyme-based glucose sensors suffer from high cost and low stability due to the inherent defects of natural enzymes.Herein,we develop a pure nanozyme-based glucose detection method using Ag@Au core/shell triangular nanoplates(TNPs),which combines glucose oxidase(GOD)-and horseradish peroxidase(HRP)-like activities of the Au shell and inherent plasmonic properties of Ag TNPs.The sensing mechanism is based on the fact that the Au shell possessed GOD-like activity,enabling the oxidation of glucose to produce H2O2,which can further etch the silver core,leading to the decrease of absorbance at 800 nm and the color change from blue to colorless.Compared with the previous nanozymes-based glucose sensors,our method avoids the use of enzymes and organic chromogenic agent.Moreover,the stability of the Ag@Au core/shell TNPs is much better than that of Ag TNPs due to the protection by the coating of the Au shell.This method was successfully applied to the detection of urine samples from patients with diabetes,indicating its practical applicability for real sample analysis. | Ao Liu Mengmeng Li Jingxiang Wang Fan Feng Yu Zhang Zhiwei Qiu Yuzhu Chen Benjamin Edem Meteku Congying Wen Zifeng Yan Jingbin Zeng | 2020 | Chinese Chemical Letters2020，31，5： | 3 |
| 6 | Neuron stem cell NLRP6 sustains hippocampal neurogenesis to resist stress-induced depression显示文摘Neurogenesis decline in hippocampal dentate gyrus(DG)participates in stress-induced depressive-like behaviors,but the underlying mechanism remains poorly understood.Here,we observed low-expression of NOD-like receptor family pyrin domain containing 6(NLRP6)in hippocampus of stress-stimulated mice,being consistent with high corticosterone level.NLRP6 was found to be abundantly expressed in neural stem cells(NSCs)of DG.Both Nlrp6 knockout(Nlrp6^(-/-))and NSCconditional Nlrp6 knockout(Nlrp6CKO)mice were susceptible to stress,being more likely to develop depressive-like behaviors.Interestingly,NLRP6 was required for NSC proliferation in sustaining hippocampal neurogenesis and reinforcing stress resilience during growing up.Nlrp6 deficiency promoted esophageal cancer-related gene 4(ECRG4)expression and caused mitochondrial dysfunction.Corticosterone as a stress factor significantly down-regulated NLRP6 expression,damaged mitochondrial function and suppressed cell proliferation in NSCs,which were blocked by Nlrp6 overexpression.ECRG4 knockdown reversed corticosterone-induced NSC mitochondrial function and cell proliferation disorders.Pioglitazone,a well-known clinical drug,up-regulated NLRP6 expression to inhibit ECRG4 expression in its protection against corticosterone-induced NSC mitochondrial dysfunction and proliferation restriction.In conclusion,this study demonstrates that NLRP6 is essential to maintain mitochondrial homeostasis and proliferation in NSCs,and identifies NLRP6 as a promising therapeutic target for hippocampal neurogenesis decline linked to depression. | Chuanfeng Tang Qiaona Wang Jingyan Shen Congying Wang Hong Ding Shiyu Wen Fan Yang Ruiqing Jiao Xingxin Wu Jianmei Li Lingdong Kong | 2023 | Acta Pharmaceutica Sinica B2023，13，5： | 3 |
| 7 | Antioxidative and immunological effects of Cyclocarya paliurus polysaccharides on the spleen injury of diabetic rats显示文摘OBJEVTIVE:To investigate the effects of Cyclocarya paliurus(C.paliurus)polysaccharides on the spleen injury of diabetic rats.METHODS:Animals were divided into 6 groups,including normal group,model group,control group,low-dose group of C.paliurus polysaccharides treatment,middle-dose group of C.paliurus polysaccharides treatment and high-dose group of C.paliurus polysaccharides treatment.Histological analysis of spleen was analyzed using hematoxilin and eosin.Levels of biological parameters and anti-oxidative enzymes were determined by spectrophotometry.Interleukin-7(IL-7)and IL-10 were measured by enzyme-linked immunosorbent assay.RESULTS:Compared with that of model group,superoxide dismutase,catalase,glutathione peroxidase,glutathione reductase level increased 78.63%(P<0.05),51.76%(P<0.05),2.95 times(P<0.01)and 41.11%(P<0.05)in the high-dose group of C.paliurus polysaccharides treatment,respectively.IL-7 and IL-10 increase 1.66(P<0.01)and 1.21 times(P<0.01)in the high-dose group of C.paliurus polysaccharides treatment,respectively.CONCLUSION:It is suggested that C.paliurus polysaccharides may play a protecting role for spleen injury of diabetic rats by enhancing the antioxidative ability and evaluating the immunity. | XIA Xichao LI Bin QIU Ju TIAN Gang CHEN Changdong LA Ming ZHANG Ke QI Jinxu LI Yanyan GAO Huashan SHAO Xiangyang SU Congying WANG Mengqi OUYANG Jingfeng | 2021 | Journal of Traditional Chinese Medicine2021，41，5： | 2 |
| 8 | Forty-five terawatt vortex ultrashort laser pulses from a chirped-pulse amplification system显示文摘We report on a vortex laser chirped-pulse amplification(CPA)system that delivers pulses with a peak power of 45 TW.A focused intensity exceeding 1019 W/cm2 has been demonstrated for the first time by the vortex amplification scheme.Compared with other schemes of strong-field vortex generation with high energy flux but narrowband vortex-converting elements at the end of the laser,an important advantage of our scheme is that we can use a broadband but size-limited q-plate to realize broadband mode-converting in the front end of the CPA system,and achieve high-power amplification with a series of amplifiers.This method is low cost and can be easily implemented in an existing laser system.The results have verified the feasibility to obtain terawatt and even petawatt vortex laser amplification by a CPA system,which has important potential applications in strong-field laser physics,for example,generation of vortex particle beams with orbital angular momentum,fast ignition for inertial confinement fusion and simulation of the extreme astrophysical environment. | Zhenkuan Chen Shuiqin Zheng Xiaoming Lu Xinliang Wang Yi Cai Congying Wang Maijie Zheng Yuexia Ai Yuxin Leng Shixiang Xu Dianyuan Fan | 2022 | High Power Laser Science and Engineering2022，10，5： | 1 |
| 9 | Differential Detection and Analysis of Pathotypes and Differentiation against Xanthomonas oryzae pv. oryzae in Southern China显示文摘Pathogenic isolates were collected from different rice-cropping regions in southern China to dissect the pathogenic disintegration and variation of Xanthomonas oryzae pv. oryzae( Xoo). Two sets of rice-Xoo differential hosts,including Chinese system with such five cultivars as IR26,Java14,Nangeng15,Tetep and Jingang 30 and international system with a series of near-isogenic lines( NILs) including IRBB5,IRBB13,IRBB3,IRBB14,IRBB2 and IR24 carrying different known resistance genes,were used to detect pathogenic disintegration for the reaction between host and pathogen with leaf-clippingmethod at the rice booting stage. The results showed the type of the pathogen were divided intosix pathotypes,i. e.,I,II,III,IV,V and IX based on the Chinese differential system,and seven pathogenicraces including R1,R2,R3,R4,R5,R8 and R10 based on the international differential system. The pathogenicity frequency of Xoo pathotypes V and IV and pathogenic races R8 and R5 were 27. 40%,19. 30% and 44. 67%,15. 34%,which were considered to be the prevailing races in southern China.Pathogenic rates of pathotypes IV,V,IX and races R8,R5 against 500 varieties derived from southern China were 96. 40%,95. 00%,50. 40%,62. 00%,and42. 60%,respectively. Among which pathotype IX was the most virulent pathotype. The pathotype V became preponderant pathotype and the new pathotype IX grew up quickly. | Shen CHEN Congying WANG Jing SU Aiqing FENG Xiaoyuan ZHU Liexian ZENG | 2018 | Agricultural Biotechnology2018，7，1： | 1 |
| 10 | Boosting Efficient Ammonia Synthesis over Atomically Dispersed Co-Based Catalyst via the Modulation of Geometric and Electronic Structures显示文摘Ammonia(NH_(3))synthesis at mild conditions is of great significance,while the significant bottleneck of this process is the activation of N_(2) to realize the desired NH_(3) synthesis performance,which requires deep insight and rational design of active sites at the atomic level.Here,were synthesized atomically dispersed Co-based catalysts with different Co-N coordination numbers(CNs)to explore the coordination-sensitive NH_(3) synthesis reaction for the first time.Our studies showed that Co-based catalysts increased the NH_(3) synthesis rate gradually with a decrease in CN.The Co-N_(2) catalyst exhibited the highest NH_(3) synthesis rate of 85.3 mmol gCo^(−1) h^(−1) at 300℃ and 1 MPa,which outperformed most of the previously reported Co-based catalysts.Various characterizations and theoretical calculations demonstrated that atomically dispersed Co catalyst with low CN could generate more unoccupied Co 3d charges and tetrahedral cobalt(Ⅱ)sites.The unoccupied Co 3d charge,in turn,promoted the electron donation from the Co active center to the antibonding π-orbital(π*)of N_(2) and expedites N_(2) hydrogenation.Furthermore,the Co-N_(2) catalyst with more tetrahedral cobalt(II)sites could effectively facilitate the desorption of N-containing intermediate species(such as*NH_(3) and*N_(2)H_(4))to obtain a high NH_(3) synthesis rate. | Yanliang Zhou Congying Wang Xuanbei Peng Tianhua Zhang Xiuyun Wang Yafei Jiang Haifeng Qi Lirong Zheng Jianxin Lin Lilong Jiang | 2022 | CCS Chemistry2022，4，5： | 1 |
| 11 | The formation of the Dabaoshan porphyry molybdenum deposit induced by slab rollback显示文摘 | LI Congying ZHANG Hong WANG Fangyue | 2012 | Lithos2012，150，： | 1 |
| 12 | Effect of pore-size distribution on Ru/ZSM-5 catalyst for enhanced N2 activation to ammonia via dissociative mechanism显示文摘In the present study,a series of Ru/ZSM-5 catalysts with different pore-size distributions were prepared and investigated for NH3 synthesis.Our studies indicate that Ru/ZSM-5-Mic with micropore structure exhibits superior NH3 synthesis rate,which is much higher than those of Ru/ZSM-5-Mac(with macroporous structure)and Ru/ZSM-5-Mes(with mesoporous structure)catalysts.A series of TPD experiments demonstrate that pore-size distributions play an important role in N2 adsorption and activation over Ru/ZSM-5.Moreover,the addition of La significantly promotes the NH3 synthesis performance over Ru/ZSM-5-Mic.Additionally,in situ DRIFTS studies indicate that the main intermediate species over Ru/ZSM-5-Mic are-NH2,and most of the surface hydrogen species desorb following the H2O-formation pathway. | Jihui Cai Congying Wang Yi Liu Jun Ni Bingyu Lin Xiuyun Wang Jianxin Lin Lilong Jiang | 2020 | Journal of Rare Earths2020，38，8： | 1 |
| 13 | A new catalyst for urea oxidation: NiCo2S4 nanowires modified 3D carbon sponge显示文摘Urea oxidation is a significant reaction for utilizing urea-rich wastewater or human urine as sustainable power sources which can ease the water eutrophication while generate electricity. A direct urea-hydrogen peroxide fuel cell is a new kind of fuel cell employing urea as fuel and hydrogen peroxide as oxidant which possesses a larger cell voltage. Herein, this work tries to promote the kinetics process of urea oxidation by preparing low-cost and high-efficient NiCo2S4 nanowires modified carbon sponge electrode. The carbon sponge used in this work with a similar three-dimensional multi-channel structure to Ni foam, is prepared by carbonizing recycled polyurethane sponge which is also a process of recycling waste. The performance of the prepared catalyst in an alkaline solution is investigated in a three-electrode system.With the introduction of Co element to the catalyst, a reduced initial urea oxidation potential and a high performance are obtained. Furthermore, a direct urea-hydrogen peroxide fuel cell is assembled using the NiCo2S4 nanowires modified carbon sponge anode. Results indicate that the prepared catalyst provides a chance to solve the current problems that hinder the development of urea electrooxidation(high initial urea oxidation potential, low performance, and high electrode costs). | Biaopeng Li Congying Song Jianjun Rong Jing Zhao Hong-En Wang Ping Yang Ke Ye Kui Cheng Kai Zhu Jun Yan Dianxue Cao Guiling Wang | 2020 | Journal of Energy Chemistry2020，29，11： | 1 |
| 14 | The SACT Template:A Human Brain Diffusion Tensor Template for School-age Children显示文摘School-age children are in a specific development stage corresponding to juvenility,when the white matter of the brain experiences ongoing maturation.Dffusion-weighted magnetic resonance imaging(DWI),especially diffusion tensor imaging(DTI),is extensively used to characterize the maturation by assessing white matter properties in vivo.In the analysis of DWI data,spatial normalization is crucial for conducting inter-subject analyses or linking the individual space with the reference space.Using tensor-based registration with an appropriate diffusion tensor template presents high accuracy regarding spatial normalization.However,there is a lack of a standardized diffusion tensor template dedicated to school-age children with ongoing brain development.Here,we established the school-age children diffusion tensor(SACT)template by optimizing tensor reorientation on high-quality DTI data from a large sample of cognitively normal participants aged 6-12 years.With an age-balanced design,the SACT template represented the entire age range well by showing high similarity to the age-specific templates.Compared with the tensor template of adults,the SACT template revealed significantly higher spatial normalization accuracy and inter-subject coherence upon evaluation of subjects in two different datasets of schoolage children.A practical application regarding the age associations with the normalized DTI-derived data was conducted to further compare the SACT template and the adult template.Although similar spatial patterns were found,the SACT template showed significant effects on the distributions of the statistical results,which may be related to the performance of spatial normalization.Looking forward,the SACT template could contribute to future studies of white matter development in both healthy and clinical populations.The SACT template is publicly available now(tp://igshare com/aricles/dataseu'SACT_.template/14071283). | Congying Chu Haoran Guan Sangma Xie Yanpei Wang Jie Luo Gai Zhao Zhiying Pan Mingming Hu Weiwei Men Shuping Tan Jia-Hong Gao Shaozheng Qin Yong He Lingzhong Fan Qi Dong Sha Tao | 2022 | Neuroscience Bulletin2022，38，6： | 1 |
| 15 | In vitro selection of salinity tolerant variants from triploid bermudagrass (Cynodon transvaalensis?×?C. dactylon) and their physiological responses to salt and drought stress显示文摘 | Shaoyun Lu Xinxiang Peng Zhenfei Guo Gengyun Zhang Zhongcheng Wang Congying Wang Chaoshu Pang Zhen Fan Jihua Wang | 2007 | Plant Cell Reports2007，，8： | 1 |
| 16 | Isolated superior mesenteric artery rupture caused by abdominal trauma显示文摘The superior mesenteric artery(SMA)is one of the visceral branches of the abdominal aorta.It has multiple branches to supply blood and nutrition to the intestinal segment,and these form an anastomosis with each other.SMA injuries are usually classified as major visceral artery injuries,and have an incidence of<1%.The clinical manifestations of patients with SMA injuries include intra-abdominal bleeding and peritoneal irritation.The compromised blood supply can lead to intestinal ischemia and perforation.These injuries are often not diagnosed in time and have significant mortality rates of 25%-68%due to the lack of specific features(Maithel et al.,2020).Not only that,but patients with less severe trauma or no visible damage on initial examination may still have clinically significant intra-abdominal injuries(Nishijima et al.,2012).Emergency departments often encounter multiple cases that require urgent diagnosis and treatment(Li et al.,2021;Zhang et al.,2021;Zhou et al.,2021),and therefore,it is imperative to diagnose and manage these rare injuries expeditiously. | Ping WANG Congying SONG Yuanqiang LU | 2022 | Journal of Zhejiang University-Science B(Biomedicine & Biotechnology)2022，23，12： | 0 |
| 17 | Uncovering the potential pathological mechanism of acute pancreatitis in patients with COVID-19 by bioinformatics methods显示文摘Severe acute respiratory syndrome coronavirus 2(SARS-CoV-2)has posed a serious challenge to emergency departments that usually encounter emergencies and severe diseases.[1-5]Angiotensin-converting enzyme 2(ACE2),a protein that interacts with the viral spike protein(s),allows SARS-CoV-2 to penetrate epithelial cells.[6]There is mounting evidence that suggests that the digestive system may also be affected.[7]An observational study described potential patterns of pancreatic injury(elevated amylase and lipase)in patients with coronavirus disease 2019(COVID-19).[8]Additionally,sporadic case reports have described secondary pancreatitis in patients with SARS-CoV-2 infection and presented imaging evidence.[9]Moreover,a previous study showed that COVID-19 patients not only have a higher risk of developing acute pancreatitis(AP),but also have a significantly higher mortality than those without COVID-19.[10]Using bioinformatics analysis,it may be possible to reveal how COVID-19 and AP are related.In this study,two RNA-seq datasets of SARS-CoV-2 and AP were selected for analysis. | Zhaodi Wang Ping Wang Xuan Lu Congying Song Shuai Jiang Li Li Yuanqiang Lu | 2023 | World Journal of Emergency Medicine2023，14，5： | 0 |
| 18 | Resistance Analysis on Major Resistant Genes of Rice Bacterial Blight in Different Donors and Genetic Background显示文摘The different donors of eight rice bacterial blight( BB) major resistant( MR) genes,Xa3,Xa4,xa5,Xa7,Xa10,Xa11,Xa14 and Xa23,were inoculated with two Chinese Xoo strains,strain IV and strain V,respectively. The strain IV was a predominant pathotype in south China,while the strain V was a severe virulentstrain. Two susceptible sterile lines and two susceptible inbred rice were employed to study the effect of geneticbackground on expression of resistance to BB for Xa4,xa5,Xa7 and Xa23. The application value of twodominant resistant genes Xa7 and Xa23 on hybrid rice was also evaluated. The results indicated that the resistance inheritance behaviors of most of the MR genes to the Xoo strains were similar and only a few genes show contradictory reaction in different donors,which suggests that the genetic background would produce an effect on the resistant expression of some R genes. Four resistant donors,IRBB4,IRBB5,IRBB7 and CBB23,were crossed with four susceptible cultivars,WufengA,JitianA,Jingang30 and IR24,respectively,using the resistant donors as male parent. The analysis of F1 populations revealed that the recessive resistance gene xa5 and dominant resistance gene Xa23 conformed to recessive and dominant expression model,respectively,while the other two dominant resistance genes,Xa4 and Xa7,conformed to dominant expression model only in some of F1 populations but not for others. In conclusion,expression of resistance for xa5 and Xa23 was independent of genetic background,while Xa4 and Xa7 show specific behaviors of resistance related to the receptor background. This study also suggests that Xa7 is not suitable for application in hybrid rice,for the F1 generation of its cross with two male sterile lines were highly susceptible,and Xa23( CBB23) had important value in improving BB resistance of hybridrice,as the F1 generations from its cross with 4 susceptible parents,including sterile lines and inbred rice,were all show highly resistant. | Liexian ZENG Congying WANG Aqing FENG Chen SHEN Jing SU Wenjiun WANG Shengyuan WU Jianyuan YANG Xiaoyuan ZHU | 2017 | Agricultural Biotechnology2017，6，5： | 0 |
| 19 | Gut microbiota affects the estrus return of sows by regulating the metabolism of sex steroid hormones显示文摘Background Sex hormones play important roles in the estrus return of post-weaning sows.Previous studies have demonstrated a complex and bi-directional regulation between sex hormones and gut microbiota.However,the extent to which the gut microbiota affects estrus return of post-weaning sows is largely unknown.Results In this study,we first screened 207 fecal samples from well-phenotyped sows by 16S rRNA gene sequencing and identified significant associations between microbes and estrus return of post-weaning sows.Using metagenomic sequencing data from 85 fecal samples,we identified 37 bacterial species that were significantly associated with estrus return.Normally returning sows were characterized by increased abundances of L.reuteri and P.copri and decreased abundances of B.fragilis,S.suis,and B.pseudolongum.The changes in gut microbial composition significantly altered the functional capacity of steroid hormone biosynthesis in the gut microbiome.The results were confirmed in a validation cohort.Significant changes in sex steroid hormones and related compounds were found between normal and non-return sows via metabolome analysis.An integrated analysis of differential bacterial species,metagenome,and fecal metabolome provided evidence that normal return-associated bacterial species L.reuteri and Prevotella spp.participated in the degradation of pregnenolone,progesterone,and testosterone,thereby promoting estrogen biosynthesis.Furthermore,the microbial metabolites related to sow energy and nutrient supply or metabolic disorders also showed relationships with sow estrus return.Conclusions An integrated analysis of differentially abundant bacterial species,metagenome,and fecal metabolome revealed the involvement of L.reuteri and Prevotella spp.in sow estrus return.These findings provide deep insight into the role of gut microbiota in the estrus return of post-weaning sows and the complex cross-talk between gut microbiota and sex hormones,suggesting that the manipulation of the gut microbiota could be an effective strategy to improve sow estrus return after weaning. | Min Liu Jia Zhang Yunyan Zhou Shuqi Xiong Mengqing Zhou Lin Wu Qin Liu Zhe Chen Hui Jiang Jiawen Yang Yuxin Liu Yaxiang Wang Congying Chen Lusheng Huang | 2024 | Journal of Animal Science and Biotechnology2024，15，2： | 0 |
| 20 | Highly efficient subnanometer Ru-based catalyst for ammonia synthesis via an associative mechanism显示文摘The industrial manufacture of ammonia(NH_(3))using Fe-based catalyst works under rigorous conditions.For the goal of carbon-neutrality,it is highly desired to develop advanced catalyst for NH_(3)synthesis at mild conditions to reduce energy consumption and CO_(2)emissions.However,the main challenge of NH_(3)synthesis at mild conditions lies in the dissociation of steady N≡N triple bond.In this work,we report the design of subnanometer Ru clusters(0.8 nm)anchored on the hollow N-doped carbon spheres catalyst(Ru-SNCs),which effectively promotes the NH_(3)synthesis at mild conditions via an associative route.The NH_(3)synthesis rate over Ru-SNCs(0.49%(mass)Ru)reaches up to 11.7 mmol NH_(3)·(g cat)^(-1)·h^(-1) at 400℃ and 3 MPa,which is superior to that of 8.3 mmol NH_(3)·(g cat)^(-1)·h^(-1) over Ru nanoparticle catalyst(1.20%(mass)Ru).Various characterizations show that the N_(2)H_(4)species are the main intermediates for NH_(3)synthesis on Ru-SNCs catalyst.It demonstrates that Ru-SNCs catalyst can follow an associative route for N_(2)activation,which circumvents the direct dissociation of N_(2)and results in highly efficient NH_(3)synthesis at mild conditions. | Yanliang Zhou Qianjin Sai Zhenni Tan Congying Wang Xiuyun Wang Bingyu Lin Jun Ni Jianxin Lin Lilong Jiang | 2022 | Chinese Journal of Chemical Engineering2022，35，3： | 0 |
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